| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Rosen, J Rak, T Leung, N M Dean, R S Kerbel, J Filmu. Activated Ras prevents downregulation of Bcl-X(L) triggered by detachment from the extracellular matrix. A mechanism of Ras-induced resistance to anoikis in intestinal epithelial cells. The Journal of cell biology. vol 149. issue 2. 2000-05-15. PMID:10769035. |
detachment of epithelial cells from the extracellular matrix (ecm) results in a form of apoptosis often referred to as anoikis. |
2000-05-15 |
2023-08-12 |
human |
| S Y Cho, R L Klemk. Extracellular-regulated kinase activation and CAS/Crk coupling regulate cell migration and suppress apoptosis during invasion of the extracellular matrix. The Journal of cell biology. vol 149. issue 1. 2000-05-11. PMID:10747099. |
extracellular-regulated kinase activation and cas/crk coupling regulate cell migration and suppress apoptosis during invasion of the extracellular matrix. |
2000-05-11 |
2023-08-12 |
Not clear |
| S Y Cho, R L Klemk. Extracellular-regulated kinase activation and CAS/Crk coupling regulate cell migration and suppress apoptosis during invasion of the extracellular matrix. The Journal of cell biology. vol 149. issue 1. 2000-05-11. PMID:10747099. |
extracellular-regulated kinase (erk) activation and molecular coupling of the adaptor proteins p130 crk-associated substrate (cas) and c-crkii (crk) represent two distinct pathways that induce cell invasion and protect cells from apoptosis in a three-dimensional collagen matrix. |
2000-05-11 |
2023-08-12 |
Not clear |
| S C Riley, C J Webb, R Leask, F M McCaig, D C How. Involvement of matrix metalloproteinases 2 and 9, tissue inhibitor of metalloproteinases and apoptosis in tissue remodelling in the sheep placenta. Journal of reproduction and fertility. vol 118. issue 1. 2000-05-09. PMID:10793622. |
involvement of matrix metalloproteinases 2 and 9, tissue inhibitor of metalloproteinases and apoptosis in tissue remodelling in the sheep placenta. |
2000-05-09 |
2023-08-12 |
Not clear |
| S C Riley, C J Webb, R Leask, F M McCaig, D C How. Involvement of matrix metalloproteinases 2 and 9, tissue inhibitor of metalloproteinases and apoptosis in tissue remodelling in the sheep placenta. Journal of reproduction and fertility. vol 118. issue 1. 2000-05-09. PMID:10793622. |
it is suggested that digestion of supporting extracellular matrix may trigger apoptosis and in some way increase the branching pattern in the villi. |
2000-05-09 |
2023-08-12 |
Not clear |
| L A Salamonsen, G T Kovacs, J K Findla. Current concepts of the mechanisms of menstruation. Bailliere's best practice & research. Clinical obstetrics & gynaecology. vol 13. issue 2. 2000-05-04. PMID:10755035. |
particular emphasis is placed on the roles of steroids, prostaglandins, endothelin, lysosomal enzymes and matrix metalloproteinases, and the involvement of the fibrinolytic system and apoptosis. |
2000-05-04 |
2023-08-12 |
Not clear |
| A K La. Molecular biology of esophageal squamous cell carcinoma. Critical reviews in oncology/hematology. vol 33. issue 2. 2000-04-24. PMID:10737369. |
the recent development includes research in etiopathogenesis (viruses and cancer susceptibility genes), keratins, tumor related genes (oncogenes, tumor suppressor genes, genes involved in metastasis and apoptosis genes), proliferation-related factors (nuclear proteins, flow cytometry/morphometry, argyrophilic nucleolar organizer region) and factors related to metastases (cell adhesion molecules and enzymes related to degradation of extracellular matrix). |
2000-04-24 |
2023-08-12 |
Not clear |
| S Kook, S R Shim, S J Choi, J Ahnn, J I Kim, S H Eom, Y K Jung, S G Paik, W K Son. Caspase-mediated cleavage of p130cas in etoposide-induced apoptotic Rat-1 cells. Molecular biology of the cell. vol 11. issue 3. 2000-04-14. PMID:10712510. |
apoptosis causes characteristic morphological changes in cells, including membrane blebbing, cell detachment from the extracellular matrix, and loss of cell-cell contacts. |
2000-04-14 |
2023-08-12 |
Not clear |
| W E Stehben. The significance of programmed cell death or apoptosis and matrix vesicles in atherogenesis. Cellular and molecular biology (Noisy-le-Grand, France). vol 46. issue 1. 2000-04-13. PMID:10726976. |
the significance of programmed cell death or apoptosis and matrix vesicles in atherogenesis. |
2000-04-13 |
2023-08-12 |
Not clear |
| W E Stehben. The significance of programmed cell death or apoptosis and matrix vesicles in atherogenesis. Cellular and molecular biology (Noisy-le-Grand, France). vol 46. issue 1. 2000-04-13. PMID:10726976. |
evaluation of apoptosis must take into account the concomitant changes in the whole vessel wall and its matrix. |
2000-04-13 |
2023-08-12 |
Not clear |
| T Di Matola, F Mueller, G Fenzi, G Rossi, M Bifulco, L A Marzano, M Vital. Serum withdrawal-induced apoptosis in thyroid cells is caused by loss of fibronectin-integrin interaction. The Journal of clinical endocrinology and metabolism. vol 85. issue 3. 2000-03-30. PMID:10720060. |
in some cell types, including a fetal thyroid cell line, denial of adhesion to extracellular matrix induces a type of apoptosis called anoikis. |
2000-03-30 |
2023-08-12 |
human |
| T Di Matola, F Mueller, G Fenzi, G Rossi, M Bifulco, L A Marzano, M Vital. Serum withdrawal-induced apoptosis in thyroid cells is caused by loss of fibronectin-integrin interaction. The Journal of clinical endocrinology and metabolism. vol 85. issue 3. 2000-03-30. PMID:10720060. |
because serum can stimulate cells to produce some components of the extracellular matrix, it was of interest to determine the role of the matrix in the apoptosis induced by serum withdrawal in normal human thyroid cells in primary culture. |
2000-03-30 |
2023-08-12 |
human |
| S Kook, S R Shim, J I Kim, J H Ahnn, Y K Jung, S G Paik, W K Son. Degradation of focal adhesion proteins during nocodazole-induced apoptosis in rat-1 cells. Cell biochemistry and function. vol 18. issue 1. 2000-03-29. PMID:10686577. |
during nocodazole-induced apoptosis, normally flat cells became rounded in shape and detached from the extracellular matrix. |
2000-03-29 |
2023-08-12 |
Not clear |
| G Feldmann, D Haouzi, A Moreau, A M Durand-Schneider, A Bringuier, A Berson, A Mansouri, D Fau, D Pessayr. Opening of the mitochondrial permeability transition pore causes matrix expansion and outer membrane rupture in Fas-mediated hepatic apoptosis in mice. Hepatology (Baltimore, Md.). vol 31. issue 3. 2000-03-15. PMID:10706558. |
opening of the mitochondrial permeability transition pore causes matrix expansion and outer membrane rupture in fas-mediated hepatic apoptosis in mice. |
2000-03-15 |
2023-08-12 |
mouse |
| W Ahmad, A A Panteleyev, A M Christian. The molecular basis of congenital atrichia in humans and mice: mutations in the hairless gene. The journal of investigative dermatology. Symposium proceedings. vol 4. issue 3. 2000-03-14. PMID:10674375. |
in hairless mice, the hair matrix cells appear to undergo a premature and massive apoptosis, together with a concomitant decline in bcl-2 expression, a loss of ncam positivity, and a disconnection with the overlying epithelial sheath essential for the movement of the dermal papilla. |
2000-03-14 |
2023-08-12 |
mouse |
| Y G Liang, A G Jorgensen, C G Kaestel, A K Wiencke, G M Lui, M H la Cour, C H Röpke, M H Nisse. Bcl-2, Bax, and c-Fos expression correlates to RPE cell apoptosis induced by UV-light and daunorubicin. Current eye research. vol 20. issue 1. 2000-03-08. PMID:10611712. |
the aim of this study was to determine the role of bcl-2, bcl-x l, bax, and c-fos in regulation of apoptosis, induced by ultraviolet-light a (uv-a) and daunorubicin (dnr), in retinal pigment epithelium (rpe) cells grown on bovine extracellular matrix (ecm)-coated or uncoated plastic dishes. |
2000-03-08 |
2023-08-12 |
cattle |
| X Cai, Y L Shen, Q Zhu, P M Jia, Y Yu, L Zhou, Y Huang, J W Zhang, S M Xiong, S J Chen, Z Y Wang, Z Chen, G Q Che. Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia. Leukemia. vol 14. issue 2. 2000-03-02. PMID:10673743. |
1.0 microm as2o3-induced apoptosis was associated with condensation of the mitochondrial matrix, disruption of mitochondrial transmembrane potentials (deltapsim) and activation of caspase-3 in acute promyelocytic leukemia (apl) cells regardless of their sensitivity to all-trans retinoic acid (atra). |
2000-03-02 |
2023-08-12 |
Not clear |
| S M Frisc. Evidence for a function of death-receptor-related, death-domain-containing proteins in anoikis. Current biology : CB. vol 9. issue 18. 2000-02-14. PMID:10508612. |
normal epithelial cells undergo apoptosis if integrinmediated matrix contacts are lost, in a process termed 'anoikis'. |
2000-02-14 |
2023-08-12 |
Not clear |
| M Rytömaa, L M Martins, J Downwar. Involvement of FADD and caspase-8 signalling in detachment-induced apoptosis. Current biology : CB. vol 9. issue 18. 2000-02-14. PMID:10508619. |
detachment of most untransformed adherent cells from the extracellular matrix promotes apoptosis, in a process termed anoikis [1] [2]. |
2000-02-14 |
2023-08-12 |
human |
| T Furui, R LaPushin, M Mao, H Khan, S R Watt, M A Watt, Y Lu, X Fang, S Tsutsui, Z H Siddik, R C Bast, G B Mill. Overexpression of edg-2/vzg-1 induces apoptosis and anoikis in ovarian cancer cells in a lysophosphatidic acid-independent manner. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 5. issue 12. 2000-02-14. PMID:10632375. |
when cells were separated from the extracellular matrix, they underwent a specialized form of apoptosis called anoikis, which is particularly important in survival of cells in the circulation during metastasis. |
2000-02-14 |
2023-08-12 |
Not clear |