| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Feng, P Precht, R Balakir, W E Horto. Evidence of a direct role for Bcl-2 in the regulation of articular chondrocyte apoptosis under the conditions of serum withdrawal and retinoic acid treatment. Journal of cellular biochemistry. vol 71. issue 2. 1998-12-22. PMID:9779827. |
apoptosis was accompanied by decreased expression of aggrecan, a chondrocyte specific matrix protein. |
1998-12-22 |
2023-08-12 |
human |
| D Haas-Kogan, N Shalev, M Wong, G Mills, G Yount, D Stoko. Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC. Current biology : CB. vol 8. issue 21. 1998-12-09. PMID:9799739. |
we explored the role of the phosphatidylinositol (pi) 3-kinase signal transduction pathway in glioblastomas, as this pathway has been shown to inhibit apoptosis induced by cytokine withdrawal and the detachment of cells from the extracellular matrix [2]. |
1998-12-09 |
2023-08-12 |
human |
| Y R Mahida, A Galvin, S Makh, S Hyde, L Sanfilippo, S P Borriello, H F Sewel. Effect of Clostridium difficile toxin A on human colonic lamina propria cells: early loss of macrophages followed by T-cell apoptosis. Infection and immunity. vol 66. issue 11. 1998-11-23. PMID:9784558. |
because these cells require adhesion-dependent signalling from the extracellular matrix for survival, their detachment from the basement membrane by other means also induces apoptosis. |
1998-11-23 |
2023-08-12 |
human |
| D Ilić, E A Almeida, D D Schlaepfer, P Dazin, S Aizawa, C H Damsk. Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis. The Journal of cell biology. vol 143. issue 2. 1998-11-12. PMID:9786962. |
extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis. |
1998-11-12 |
2023-08-12 |
Not clear |
| M Vitale, T Di Matola, G Fenzi, M Illario, G Ross. Fibronectin is required to prevent thyroid cell apoptosis through an integrin-mediated adhesion mechanism. The Journal of clinical endocrinology and metabolism. vol 83. issue 10. 1998-11-05. PMID:9768683. |
apoptosis or programmed cell death occurs in a wide variety of cell types when adhesion to extracellular matrix (ecm) is denied. |
1998-11-05 |
2023-08-12 |
Not clear |
| M Vitale, T Di Matola, G Fenzi, M Illario, G Ross. Fibronectin is required to prevent thyroid cell apoptosis through an integrin-mediated adhesion mechanism. The Journal of clinical endocrinology and metabolism. vol 83. issue 10. 1998-11-05. PMID:9768683. |
these results suggest that the tad-2 cell line is a good model to study thyroid cell-ecm interaction, that fn, assembled into insoluble matrix, is required for cytoskeletal organization and to prevent thyroid cell apoptosis, and that integrin-mediated adhesion is involved in this process. |
1998-11-05 |
2023-08-12 |
Not clear |
| P Bianco, F D Cancedda, M Riminucci, R Cancedd. Bone formation via cartilage models: the "borderline" chondrocyte. Matrix biology : journal of the International Society for Matrix Biology. vol 17. issue 3. 1998-11-03. PMID:9707341. |
hypertrophic chondrocytes located in different cartilage areas are exposed to an inappropriate matrix and endocrine/paracrine environment, cannot differentiate to osteoblast-like cells and therefore undergo apoptosis. |
1998-11-03 |
2023-08-12 |
Not clear |
| M Delcommenne, C Tan, V Gray, L Rue, J Woodgett, S Dedha. Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 19. 1998-10-26. PMID:9736715. |
overexpression of ilk in epithelial cells disrupts cell-extracellular matrix as well as cell-cell interactions, suppresses suspension-induced apoptosis (also called anoikis), and stimulates anchorage-independent cell cycle progression. |
1998-10-26 |
2023-08-12 |
Not clear |
| P C Singhal, P Sharma, R Loona, N Gibbons, N Franki, P E Klotma. Enhanced proliferation, apoptosis, and matrix accumulation by mesangial cells derived from HIV-1 transgenic mice. Journal of investigative medicine : the official publication of the American Federation for Clinical Research. vol 46. issue 6. 1998-10-19. PMID:9737092. |
enhanced proliferation, apoptosis, and matrix accumulation by mesangial cells derived from hiv-1 transgenic mice. |
1998-10-19 |
2023-08-12 |
mouse |
| P C Singhal, P Sharma, R Loona, N Gibbons, N Franki, P E Klotma. Enhanced proliferation, apoptosis, and matrix accumulation by mesangial cells derived from HIV-1 transgenic mice. Journal of investigative medicine : the official publication of the American Federation for Clinical Research. vol 46. issue 6. 1998-10-19. PMID:9737092. |
we evaluated the proliferation, apoptosis, and matrix accumulation by mesangial cells derived from mice transgenic for hiv-1 genes as well as from nontransgenic mice. |
1998-10-19 |
2023-08-12 |
mouse |
| N N Khodarev, I A Sokolova, A T Vaugha. Association between DNA cleavage during apoptosis and regions of chromatin replication. Journal of cellular biochemistry. vol 70. issue 4. 1998-10-15. PMID:9712157. |
it is proposed that these fragments contain a subset of replicon dna that is excised during apoptosis through recognition of their weak attachment to the nuclear matrix within the replication domain. |
1998-10-15 |
2023-08-12 |
Not clear |
| J J Feige, M Keramidas, E M Chamba. Hormonally regulated components of the adrenocortical cell environment and the control of adrenal cortex homeostasis. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 30. issue 6-7. 1998-10-13. PMID:9694573. |
in the adrenal cortex, five main biological functions are potentially regulated by components of the extracellular matrix : stem cell commitment into the adrenocyte differentiation pathway, terminal differentiation toward the three distinct adrenocyte phenotypes, centripetal migration, apoptosis and the formation of the capillary network. |
1998-10-13 |
2023-08-12 |
cattle |
| A L Boral, S Dessain, B A Chabne. Clinical evaluation of biologically targeted drugs: obstacles and opportunities. Cancer chemotherapy and pharmacology. vol 42 Suppl. 1998-10-07. PMID:9750025. |
these processes include cell cycle control, signal transduction pathways, apoptosis, telomere stability, angiogenesis, and interactions with the extracellular matrix. |
1998-10-07 |
2023-08-12 |
Not clear |
| Y Yamada, S Endo, T Kasai, S Koike, T Takakuwa, Y Inoue, M Niimi, Y Endo, G Wakabayashi, K Inad. Nuclear matrix protein, tumor necrosis factor-alpha, and nitrite/nitrate levels in patients with multiple organ dysfunction syndrome. Research communications in molecular pathology and pharmacology. vol 100. issue 1. 1998-09-16. PMID:9644723. |
nuclear matrix protein (nmp), an indicator of apoptosis, was analyzed in patients with multiple organ dysfunction syndrome (mods). |
1998-09-16 |
2023-08-12 |
Not clear |
| R Banjerdpongchai, P Wilairat, S Fucharoen, A Bunyaratve. Morphological alterations and apoptosis of endothelial cells induced by thalassemic serum in vitro. The Southeast Asian journal of tropical medicine and public health. vol 28 Suppl 3. 1998-09-14. PMID:9640618. |
such treated ecs presented morphological characteristics of apoptosis as shown by the appearance of compact cytosol, membrane blebbing, margination of nuclear matrix, condensed nuclei, and fragmented bodies. |
1998-09-14 |
2023-08-12 |
human |
| J P Iredale, R C Benyon, J Pickering, M McCullen, M Northrop, S Pawley, C Hovell, M J Arthu. Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors. The Journal of clinical investigation. vol 102. issue 3. 1998-08-26. PMID:9691091. |
we suggest that apoptosis of activated hsc may vitally contribute to resolution of fibrosis by acting as a mechanism for removing the cell population responsible for both producing fibrotic neomatrix and protecting this matrix from degradation via their production of timps. |
1998-08-26 |
2023-08-12 |
rat |
| F Fukai, M Mashimo, K Akiyama, T Goto, S Tanuma, T Katayam. Modulation of apoptotic cell death by extracellular matrix proteins and a fibronectin-derived antiadhesive peptide. Experimental cell research. vol 242. issue 1. 1998-08-10. PMID:9665806. |
cell adhesion to the extracellular matrix (ecm) has been implicated in apoptosis in anchorage-dependent cell types. |
1998-08-10 |
2023-08-12 |
human |
| F G Gervais, N A Thornberry, S C Ruffolo, D W Nicholson, S Ro. Caspases cleave focal adhesion kinase during apoptosis to generate a FRNK-like polypeptide. The Journal of biological chemistry. vol 273. issue 27. 1998-08-06. PMID:9642276. |
it suppresses apoptosis by transducing survival signals that emanate from focal adhesions via the clustering of transmembrane integrins by components of the extracellular matrix. |
1998-08-06 |
2023-08-12 |
Not clear |
| A R Amin, S B Abramso. The role of nitric oxide in articular cartilage breakdown in osteoarthritis. Current opinion in rheumatology. vol 10. issue 3. 1998-08-03. PMID:9608331. |
in vitro, nitric oxide exerts detrimental effects on chondrocyte functions, including the inhibition of collagen and proteoglycan synthesis, enhanced apoptosis, and an inhibition of b1 integrin-dependent adhesion to the extra-cellular matrix. |
1998-08-03 |
2023-08-12 |
Not clear |
| W E Stehben. Apoptosis and matrix vesicles in the genesis of arterial aneurysms of cerebral arteries. Stroke. vol 29. issue 7. 1998-07-30. PMID:9660409. |
apoptosis and matrix vesicles in the genesis of arterial aneurysms of cerebral arteries. |
1998-07-30 |
2023-08-12 |
Not clear |