| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Sethi, R C Rintoul, S M Moore, A C MacKinnon, D Salter, C Choo, E R Chilvers, I Dransfield, S C Donnelly, R Strieter, C Haslet. Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo. Nature medicine. vol 5. issue 6. 1999-07-01. PMID:10371505. |
extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo. |
1999-07-01 |
2023-08-12 |
Not clear |
| A Solovey, L Gui, S Ramakrishnan, M H Steinberg, R P Hebbe. Sickle cell anemia as a possible state of enhanced anti-apoptotic tone: survival effect of vascular endothelial growth factor on circulating and unanchored endothelial cells. Blood. vol 93. issue 11. 1999-06-24. PMID:10339489. |
we studied whether apoptosis is occurring in circulating endothelial cells (cec) that have lost the survival signals derived from anchorage to extracellular matrix. |
1999-06-24 |
2023-08-12 |
Not clear |
| A Solovey, L Gui, S Ramakrishnan, M H Steinberg, R P Hebbe. Sickle cell anemia as a possible state of enhanced anti-apoptotic tone: survival effect of vascular endothelial growth factor on circulating and unanchored endothelial cells. Blood. vol 93. issue 11. 1999-06-24. PMID:10339489. |
in vitro experiments showed that vegf inhibits apoptosis for cultured endothelial cells that are kept unanchored and not allowed to re-establish attachment to extracellular matrix, thus demonstrating that vegf provides survival signals independent of its ability to promote matrix reattachment. |
1999-06-24 |
2023-08-12 |
Not clear |
| N Farrelly, Y J Lee, J Oliver, C Dive, C H Streul. Extracellular matrix regulates apoptosis in mammary epithelium through a control on insulin signaling. The Journal of cell biology. vol 144. issue 6. 1999-06-14. PMID:10087274. |
extracellular matrix regulates apoptosis in mammary epithelium through a control on insulin signaling. |
1999-06-14 |
2023-08-12 |
Not clear |
| C M Perks, P V Newcomb, M R Norman, J M Holl. Effect of insulin-like growth factor binding protein-1 on integrin signalling and the induction of apoptosis in human breast cancer cells. Journal of molecular endocrinology. vol 22. issue 2. 1999-06-09. PMID:10194517. |
furthermore, after 24 h both peptides caused detachment from the matrix and the induction of apoptosis. |
1999-06-09 |
2023-08-12 |
human |
| S A Cente. Chronic liver disease: current concepts of disease mechanisms. The Journal of small animal practice. vol 40. issue 3. 1999-06-08. PMID:10200920. |
secondarily, cells and mediators associated with inflammation, pathological expression of major histocompatibility foci on hepatocytes and biliary epithelia, aberrant initiation of apoptosis, modification of the extracellular matrix, and depletion of natural antioxidants can each play pivotal roles. |
1999-06-08 |
2023-08-12 |
Not clear |
| S Hess, R Gulati, J J Pelus. Hepatocyte growth factor induces rat ovarian surface epithelial cell mitosis or apoptosis depending on the presence or absence of an extracellular matrix. Endocrinology. vol 140. issue 6. 1999-06-03. PMID:10342884. |
hepatocyte growth factor induces rat ovarian surface epithelial cell mitosis or apoptosis depending on the presence or absence of an extracellular matrix. |
1999-06-03 |
2023-08-12 |
rat |
| S J Watton, J Downwar. Akt/PKB localisation and 3' phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction. Current biology : CB. vol 9. issue 8. 1999-06-01. PMID:10226029. |
adhesion of epithelial cells to extracellular matrix leads to protection from apoptosis via the activation of phosphoinositide (pi) 3-kinase and akt/pkb through an unknown mechanism [3] [4]. |
1999-06-01 |
2023-08-12 |
Not clear |
| M Kruidering, B van de Water, Y Zhan, J J Baelde, E Heer, G J Mulder, J L Stevens, J F Nagelkerk. Cisplatin effects on F-actin and matrix proteins precede renal tubular cell detachment and apoptosis in vitro. Cell death and differentiation. vol 5. issue 7. 1999-05-27. PMID:10200515. |
cisplatin effects on f-actin and matrix proteins precede renal tubular cell detachment and apoptosis in vitro. |
1999-05-27 |
2023-08-12 |
Not clear |
| M Kruidering, B van de Water, Y Zhan, J J Baelde, E Heer, G J Mulder, J L Stevens, J F Nagelkerk. Cisplatin effects on F-actin and matrix proteins precede renal tubular cell detachment and apoptosis in vitro. Cell death and differentiation. vol 5. issue 7. 1999-05-27. PMID:10200515. |
overexpression of bcl-2 also prevented apoptosis, but did not prevent damage to the f-actin skeleton or the reduction of mrna expression of the matrix proteins. |
1999-05-27 |
2023-08-12 |
Not clear |
| S E Wilson, J J Liu, R R Moha. Stromal-epithelial interactions in the cornea. Progress in retinal and eye research. vol 18. issue 3. 1999-05-25. PMID:10192515. |
il-1 appears to be a master regulator of corneal wound healing that modulates functions such as matrix metalloproteinase production, hgf and kgf production, and apoptosis of keratocyte cells following injury. |
1999-05-25 |
2023-08-12 |
Not clear |
| F Grinnell, M Zhu, M A Carlson, J M Abram. Release of mechanical tension triggers apoptosis of human fibroblasts in a model of regressing granulation tissue. Experimental cell research. vol 248. issue 2. 1999-05-25. PMID:10222153. |
studies on the mechanism regulating apoptosis under these conditions established that the apoptotic response does not require differentiation of cells into myofibroblasts but is governed by a combination of mechanical tension and growth factors in the collagen matrix. |
1999-05-25 |
2023-08-12 |
human |
| K C Fang, P J Wolters, M Steinhoff, A Bidgol, J L Blount, G H Caughe. Mast cell expression of gelatinases A and B is regulated by kit ligand and TGF-beta. Journal of immunology (Baltimore, Md. : 1950). vol 162. issue 9. 1999-05-20. PMID:10228034. |
the profibrotic cytokine tgf-beta virtually abolishes the gelatinase b mrna signal and also attenuates kit ligand-mediated induction of gelatinase b expression, suggesting that an excess of tgf-beta in inflamed or injured tissues may alter mast cell expression of gelatinase b, which is implicated in extracellular matrix degradation, angiogenesis, and apoptosis. |
1999-05-20 |
2023-08-12 |
dog |
| C Köhler, A Gahm, T Noma, A Nakazawa, S Orrenius, B Zhivotovsk. Release of adenylate kinase 2 from the mitochondrial intermembrane space during apoptosis. FEBS letters. vol 447. issue 1. 1999-05-17. PMID:10218571. |
however, three isozymes, ak1, ak2 and ak3, have been characterized in mammalian cells and shown to be localized in the cytosol, mitochondrial intermembrane space and mitochondrial matrix, respectively, and it is unknown which one of these isozymes accumulates in the cytosol during apoptosis. |
1999-05-17 |
2023-08-12 |
Not clear |
| K Mansfield, R Rajpurohit, I M Shapir. Extracellular phosphate ions cause apoptosis of terminally differentiated epiphyseal chondrocytes. Journal of cellular physiology. vol 179. issue 3. 1999-05-13. PMID:10228946. |
results of this study suggest that pi is a stage-specific inducer of apoptosis in maturing chondrocytes and that this role may be linked to chondrocyte maturation and mineralization of the extracellular matrix. |
1999-05-13 |
2023-08-12 |
Not clear |
| A A Amato, C E Jackson, S Lampkin, K Kagan-Halle. Myofibrillar myopathy: no evidence of apoptosis by TUNEL. Neurology. vol 52. issue 4. 1999-04-30. PMID:10078743. |
muscle biopsy specimens demonstrate increased expression of cell cycle regulatory proteins as well as the ectopic expression of lamin b and nuclear matrix protein in the cytoplasm, suggesting the possibility of apoptosis. |
1999-04-30 |
2023-08-12 |
Not clear |
| S Baize, E M Leroy, M C Georges-Courbot, M Capron, J Lansoud-Soukate, P Debré, S P Fisher-Hoch, J B McCormick, A J George. Defective humoral responses and extensive intravascular apoptosis are associated with fatal outcome in Ebola virus-infected patients. Nature medicine. vol 5. issue 4. 1999-04-29. PMID:10202932. |
dna fragmentation in blood leukocytes and release of 41/7 nuclear matrix protein in plasma indicated that massive intravascular apoptosis proceeded relentlessly during the last 5 days of life. |
1999-04-29 |
2023-08-12 |
Not clear |
| L Borradori, A Sonnenber. Structure and function of hemidesmosomes: more than simple adhesion complexes. The Journal of investigative dermatology. vol 112. issue 4. 1999-04-21. PMID:10201522. |
it has become clear that the alpha6beta4 integrin, a major component of hemidesmosomes, is able to transduce signals from the extracellular matrix to the interior of the cell, that critically modulate the organization of the cytoskeleton, proliferation, apoptosis, and differentiation. |
1999-04-21 |
2023-08-12 |
Not clear |
| R Kettritz, Y X Xu, T Kerren, P Quass, J B Klein, F C Luft, H Halle. Extracellular matrix regulates apoptosis in human neutrophils. Kidney international. vol 55. issue 2. 1999-04-15. PMID:9987080. |
extracellular matrix regulates apoptosis in human neutrophils. |
1999-04-15 |
2023-08-12 |
human |
| B Valentinis, A Morrione, F Peruzzi, M Prisco, K Reiss, R Baserg. Anti-apoptotic signaling of the IGF-I receptor in fibroblasts following loss of matrix adhesion. Oncogene. vol 18. issue 10. 1999-04-13. PMID:10086337. |
we have investigated igf-ir signaling in cells in anoikis, a form of apoptosis that occurs when cells are denied attachment to the extra-cellular matrix. |
1999-04-13 |
2023-08-12 |
mouse |