| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J M Hettasch, N Bandarenko, J L Burchette, T S Lai, J R Marks, Z A Haroon, K Peters, M W Dewhirst, J D Iglehart, C S Greenber. Tissue transglutaminase expression in human breast cancer. Laboratory investigation; a journal of technical methods and pathology. vol 75. issue 5. 1996-12-30. PMID:8941210. |
tissue transglutaminase (ttg) is postulated to play a role in apoptosis, cell adhesion, metastasis, and extracellular matrix (ecm) assembly. |
1996-12-30 |
2023-08-12 |
human |
| K Lee, B Lanske, A C Karaplis, J D Deeds, H Kohno, R A Nissenson, H M Kronenberg, G V Segr. Parathyroid hormone-related peptide delays terminal differentiation of chondrocytes during endochondral bone development. Endocrinology. vol 137. issue 11. 1996-12-17. PMID:8895385. |
terminal differentiation of chondrocytes, which was characterized by cell hypertrophy, apoptosis (dna fragmentation and decreased bcl-2 mrna expression), and matrix mineralization, was more advanced in growth cartilage of pthrp(-/-), compared with pthrp(+/+) animals. |
1996-12-17 |
2023-08-12 |
mouse |
| T C Ho, L V Del Priore, H J Kapla. En bloc transfer of extracellular matrix in vitro. Current eye research. vol 15. issue 9. 1996-12-10. PMID:8921221. |
extracellular matrix (ecm) plays a major role in the development and regeneration of various epithelial cells including retinal pigment epithelium (rpe), and attachment to ecm inhibits rpe apoptosis. |
1996-12-10 |
2023-08-12 |
human |
| C A Delaney, B Tyrberg, L Bouwens, H Vaghef, B Hellman, D L Eiziri. Sensitivity of human pancreatic islets to peroxynitrite-induced cell dysfunction and death. FEBS letters. vol 394. issue 3. 1996-11-20. PMID:8830662. |
dna strand breaks in single human and rat islet cells are detectable after acute peroxynitrite exposure, followed by a decrease in islet cell survival after 1 h and 24 h. cell death appeared to occur via a toxic cell death mechanism (necrosis) rather than apoptosis, as suggested by vital staining and ultrastructural evidence of early membrane and organelle degradation, mitochondrial swelling and loss of matrix. |
1996-11-20 |
2023-08-12 |
human |
| J A Maier, D Morelli, S Ménard, M I Colnaghi, A Balsar. Tumor-necrosis-factor-induced fibroblast growth factor-1 acts as a survival factor in a transformed endothelial cell line. The American journal of pathology. vol 149. issue 3. 1996-10-17. PMID:8780398. |
endothelial cells undergo apoptosis after withdrawal of growth factors, alterations in the extracellular matrix, or exposure to cytokines. |
1996-10-17 |
2023-08-12 |
human |
| C A Casiano, S J Martin, D R Green, E M Ta. Selective cleavage of nuclear autoantigens during CD95 (Fas/APO-1)-mediated T cell apoptosis. The Journal of experimental medicine. vol 184. issue 2. 1996-09-23. PMID:8760832. |
several of the cleaved autoantigens are involved in ensuring the integrity and proper conformation of dna in the nucleus through interactions with the nuclear matrix, suggesting the possibility that their cleavage may contribute to the collapse of nuclear structure during apoptosis. |
1996-09-23 |
2023-08-12 |
human |
| S M Frisch, K Vuori, E Ruoslahti, P Y Chan-Hu. Control of adhesion-dependent cell survival by focal adhesion kinase. The Journal of cell biology. vol 134. issue 3. 1996-09-12. PMID:8707856. |
the interactions of integrins with extracellular matrix proteins can activate focal adhesion kinase (fak) and suppress apoptosis in normal epithelial and endothelial cells; this subset of apoptosis has been termed "anoikis." |
1996-09-12 |
2023-08-12 |
mouse |
| M O Boluyt, O H Bing, E G Lakatt. The ageing spontaneously hypertensive rat as a model of the transition from stable compensated hypertrophy to heart failure. European heart journal. vol 16 Suppl N. 1996-08-21. PMID:8682057. |
research opportunities include investigation of apoptosis as a mechanism of cell loss, delineation of the regulatory roles of tgf-beta 1 and the renin-angiotensin-aldosterone system in matrix accumulation, and studies of proteinase cascades that regulate matrix remodelling. |
1996-08-21 |
2023-08-12 |
rat |
| L Borge, S Demignot, M Adolph. Type II transglutaminase expression in rabbit articular chondrocytes in culture: relation with cell differentiation, cell growth, cell adhesion and cell apoptosis. Biochimica et biophysica acta. vol 1312. issue 2. 1996-08-09. PMID:8672533. |
depending on the cell type studied, the involvement of type ii transglutaminase (tgase) has been proposed in almost any event of the cell life such as differentiation, apoptosis, growth, aging, cell morphology and adhesion, metastatic capacity or extracellular matrix stabilization. |
1996-08-09 |
2023-08-12 |
rabbit |
| S M Frisc. Reversal of malignancy by the adenovirus E1a gene. Mutation research. vol 350. issue 1. 1996-07-26. PMID:8657190. |
furthermore, epithelial cells are sensitive to a form of apoptosis - 'anoikis' - that is induced by detachment from extracellular matrix. |
1996-07-26 |
2023-08-12 |
Not clear |
| C S Williams, R N DuBoi. Prostaglandin endoperoxide synthase: why two isoforms? The American journal of physiology. vol 270. issue 3 Pt 1. 1996-07-05. PMID:8638704. |
overexpression of cox-2 in intestinal epithelial cells results in increased adhesion to extracellular matrix proteins and inhibition of apoptosis. |
1996-07-05 |
2023-08-12 |
mouse |
| H M Beere, C M Chresta, J A Hickma. Selective inhibition of topoisomerase II by ICRF-193 does not support a role for topoisomerase II activity in the fragmentation of chromatin during apoptosis of human leukemia cells. Molecular pharmacology. vol 49. issue 5. 1996-06-19. PMID:8622634. |
topoisomerase ii plays a role in the attachment of 50-kilobase domains of dna to the nuclear matrix; fragments of this size are cleaved during apoptosis. |
1996-06-19 |
2023-08-12 |
human |
| N Boudreau, Z Werb, M J Bissel. Suppression of apoptosis by basement membrane requires three-dimensional tissue organization and withdrawal from the cell cycle. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 8. 1996-06-18. PMID:8622967. |
the basement membrane (bm) extracellular matrix induces differentiation and suppresses apoptosis in mammary epithelial cells, whereas cells lacking bm lose their differentiated phenotype and undergo apoptosis. |
1996-06-18 |
2023-08-12 |
Not clear |
| S Hara, H D Halicka, S Bruno, J Gong, F Traganos, Z Darzynkiewic. Effect of protease inhibitors on early events of apoptosis. Experimental cell research. vol 223. issue 2. 1996-05-03. PMID:8601414. |
because nuclear matrix proteins and histones stabilize dna in situ, and the decrease in dna stability which occurs during apoptosis is precluded by the inhibitors, it is likely that serine proteases may degrade dna stabilizing proteins. |
1996-05-03 |
2023-08-12 |
human |
| C J Narvaez, K Vanweelden, I Byrne, J Wels. Characterization of a vitamin D3-resistant MCF-7 cell line. Endocrinology. vol 137. issue 2. 1996-04-09. PMID:8593782. |
we have previously demonstrated that 1,25-(oh)2d3 induces morphology (pyknotic nuclei, chromatin and cytoplasmic condensation, and nuclear matrix protein reorganization) consistent with the activation of apoptosis in mcf-7 cells. |
1996-04-09 |
2023-08-12 |
Not clear |
| L R Lund, J Rømer, N Thomasset, H Solberg, C Pyke, M J Bissell, K Danø, Z Wer. Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways. Development (Cambridge, England). vol 122. issue 1. 1996-03-07. PMID:8565829. |
our data support the hypothesis that there are at least two distinct phases of involution: an initial phase, characterized by induction of the apoptosis-associated genes sgp-2 and ice and apoptosis of fully differentiated mammary epithelial cells without visible degradation of the extracellular matrix, and a second phase, characterized by extracellular matrix remodeling and altered mesenchymal-epithelial interactions, followed by apoptosis of cells that are losing differentiated functions. |
1996-03-07 |
2023-08-12 |
mouse |
| M M Tinnemans, M H Lenders, G P ten Velde, F C Ramaekers, B Schutt. Alterations in cytoskeletal and nuclear matrix-associated proteins during apoptosis. European journal of cell biology. vol 68. issue 1. 1996-02-22. PMID:8549588. |
it appeared that nuclear matrix components remained detectable in cells undergoing spontaneous apoptosis. |
1996-02-22 |
2023-08-12 |
Not clear |
| M M Tinnemans, M H Lenders, G P ten Velde, F C Ramaekers, B Schutt. Alterations in cytoskeletal and nuclear matrix-associated proteins during apoptosis. European journal of cell biology. vol 68. issue 1. 1996-02-22. PMID:8549588. |
the persistence of nuclear matrix components is therefore a useful marker for the detection of apoptosis. |
1996-02-22 |
2023-08-12 |
Not clear |
| R C Bates, L F Lincz, G F Burn. Involvement of integrins in cell survival. Cancer metastasis reviews. vol 14. issue 3. 1996-02-20. PMID:8548868. |
the extracellular matrix (ecm) is known to play a regulatory role in cellular growth and differentiation, but only more recently has it been recognized as a regulator of apoptosis. |
1996-02-20 |
2023-08-12 |
Not clear |
| G J Gibson, W J Kohler, M B Schaffle. Chondrocyte apoptosis in endochondral ossification of chick sterna. Developmental dynamics : an official publication of the American Association of Anatomists. vol 203. issue 4. 1996-01-17. PMID:7496038. |
light microscopy of resorbing sterna demonstrated chondrocyte condensation at the interface with the invading vasculature and electron microscopy demonstrated a range of chondrocyte morphologies, including retraction from the pericellular matrix, cytoplasmic and nuclear condensation, and vesiculation suggestive of sequential changes characteristic of apoptosis. |
1996-01-17 |
2023-08-12 |
chicken |