| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Varedi, E E Tredget, A Ghahary, P G Scot. Stress-relaxation and contraction of a collagen matrix induces expression of TGF-beta and triggers apoptosis in dermal fibroblasts. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 78. issue 4. 2001-01-18. PMID:11012081. |
these results show that alterations in the mechanical properties of matrix can induce the expression of tgf-beta and trigger apoptosis in dermal fibroblasts. |
2001-01-18 |
2023-08-12 |
human |
| M T Santini, G Rainaldi, P L Indovin. Apoptosis, cell adhesion and the extracellular matrix in the three-dimensional growth of multicellular tumor spheroids. Critical reviews in oncology/hematology. vol 36. issue 2-3. 2001-01-09. PMID:11033298. |
apoptosis, cell adhesion and the extracellular matrix in the three-dimensional growth of multicellular tumor spheroids. |
2001-01-09 |
2023-08-12 |
Not clear |
| M T Santini, G Rainaldi, P L Indovin. Apoptosis, cell adhesion and the extracellular matrix in the three-dimensional growth of multicellular tumor spheroids. Critical reviews in oncology/hematology. vol 36. issue 2-3. 2001-01-09. PMID:11033298. |
in the last few years, it has become increasingly apparent that cell survival and death, especially apoptosis, strongly depend on cell adhesion and the extracellular matrix. |
2001-01-09 |
2023-08-12 |
Not clear |
| M T Santini, G Rainaldi, P L Indovin. Apoptosis, cell adhesion and the extracellular matrix in the three-dimensional growth of multicellular tumor spheroids. Critical reviews in oncology/hematology. vol 36. issue 2-3. 2001-01-09. PMID:11033298. |
in the present review, after a general overview of the current knowledge regarding apoptosis, cell adhesion and the extracellular matrix, the results obtained utilizing multicellular tumor spheroids in these types of studies are discussed. |
2001-01-09 |
2023-08-12 |
Not clear |
| O Ouda. Spheroids: relation between tumour and endothelial cells. Critical reviews in oncology/hematology. vol 36. issue 2-3. 2001-01-09. PMID:11033300. |
indeed cell-cell and cell-extracellular matrix contacts are necessary for much cellular function such as differentiation, proliferation, cell death, apoptosis and angiogenesis. |
2001-01-09 |
2023-08-12 |
Not clear |
| N N Khodarev, T Bennett, N Shearing, I Sokolova, J Koudelik, S Walter, M Villalobos, A T Vaugha. LINE L1 retrotransposable element is targeted during the initial stages of apoptotic DNA fragmentation. Journal of cellular biochemistry. vol 79. issue 3. 2001-01-05. PMID:10972985. |
these data indicate that the site of chromatin loop formation at the nuclear matrix may be a specific target for early dna fragmentation events during apoptosis. |
2001-01-05 |
2023-08-12 |
human |
| L E Goldfinger, L Jiang, S B Hopkinson, M S Stack, J C Jone. Spatial regulation and activity modulation of plasmin by high affinity binding to the G domain of the alpha 3 subunit of laminin-5. The Journal of biological chemistry. vol 275. issue 45. 2001-01-04. PMID:10956663. |
cells in complex tissues contact extracellular matrix that interacts with integrin receptors to influence gene expression, proliferation, apoptosis, adhesion, and motility. |
2001-01-04 |
2023-08-12 |
Not clear |
| A Fayyazi, S Schweyer, B Eichmeyer, J Herms, B Hemmerlein, H J Radzun, H Berge. Expression of IFNgamma, coexpression of TNFalpha and matrix metalloproteinases and apoptosis of T lymphocytes and macrophages in granuloma annulare. Archives of dermatological research. vol 292. issue 8. 2001-01-04. PMID:10994772. |
expression of ifngamma, coexpression of tnfalpha and matrix metalloproteinases and apoptosis of t lymphocytes and macrophages in granuloma annulare. |
2001-01-04 |
2023-08-12 |
Not clear |
| S S Nadadur, M C Schladweiler, U P Kodavant. A pulmonary rat gene array for screening altered expression profiles in air pollutant-induced lung injury. Inhalation toxicology. vol 12. issue 12. 2001-01-03. PMID:11114790. |
pulmonary tissue injury and repair processes involve complex and coordinated cellular events such as necrosis, inflammation, cell growth/differentiation, apoptosis, and remodeling of extracellular matrix. |
2001-01-03 |
2023-08-12 |
rat |
| M E Cho. Mechanism of transforming growth factor-beta1 signaling:. Kidney international. Supplement. vol 77. 2001-01-02. PMID:10997691. |
transforming growth factor-beta1 (tgf-beta1) regulates diverse biologic activities including cell growth, cell death or apoptosis, cell differentiation, and extracellular matrix (ecm) synthesis. |
2001-01-02 |
2023-08-12 |
Not clear |
| H Makino, H Sugiyama, N Kashihar. Apoptosis and extracellular matrix-cell interactions in kidney disease. Kidney international. Supplement. vol 77. 2001-01-02. PMID:10997693. |
our recent study indicated that basement membrane matrix (a model for normal ecm components) prevented cultured mc from undergoing apoptosis after serum deprivation, thus promoting their survival, compared with type i collagen matrix (a model for abnormal ecm components). |
2001-01-02 |
2023-08-12 |
rat |
| P J Best, A Lerma. Endothelin in cardiovascular disease: from atherosclerosis to heart failure. Journal of cardiovascular pharmacology. vol 35. issue 4 Suppl 2. 2000-12-22. PMID:10976784. |
this peptide not only alters vascular tone and cardiac hemodynamics, but also has a substantial role in the regulation of cellular proliferation and apoptosis, activation of monocytes and cellular matrix production. |
2000-12-22 |
2023-08-12 |
Not clear |
| C M Ferguson, E M Schwarz, P R Reynolds, J E Puzas, R N Rosier, R J O'Keef. Smad2 and 3 mediate transforming growth factor-beta1-induced inhibition of chondrocyte maturation. Endocrinology. vol 141. issue 12. 2000-12-22. PMID:11108288. |
transforming growth factor-beta (tgf-beta) is a multifunctional regulator of a variety of cellular functions, including proliferation, differentiation, matrix synthesis, and apoptosis. |
2000-12-22 |
2023-08-12 |
Not clear |
| E Tonner, G J Allan, D J Flin. Hormonal control of plasmin and tissue-type plasminogen activator activity in rat milk during involution of the mammary gland. The Journal of endocrinology. vol 167. issue 2. 2000-12-15. PMID:11054640. |
since alpha(s2)-casein also binds plasminogen and tissue-type plasminogen activator (t-pa), resulting in the conversion of plasminogen to plasmin, and since igfbp-5 binds to plasminogen activator inhibitor-1 (pai-1), we investigated whether apoptosis and extracellular matrix (ecm) degradation might be coordinately controlled by gh and prl possibly acting through igfbp-5. |
2000-12-15 |
2023-08-12 |
rat |
| M R Piano, S D Kim, C Jarvi. Cellular events linked to cardiac remodeling in heart failure: targets for pharmacologic intervention. The Journal of cardiovascular nursing. vol 14. issue 4. 2000-11-21. PMID:10902101. |
rather, the syndrome of heart failure is more complex and is characterized by abnormal myocyte growth, proliferation of cells in the extracellular matrix, and myocyte cell loss (apoptosis)--all of which culminate in significant structural remodeling of the heart and loss of ventricular function. |
2000-11-21 |
2023-08-12 |
Not clear |
| G Arrode, C Boccaccio, J Lulé, S Allart, N Moinard, J P Abastado, A Alam, C Davrinch. Incoming human cytomegalovirus pp65 (UL83) contained in apoptotic infected fibroblasts is cross-presented to CD8(+) T cells by dendritic cells. Journal of virology. vol 74. issue 21. 2000-11-20. PMID:11024130. |
in this study, we show that infection by hcmv ad169 induced sensitization of mrc5 fibroblasts to tumor necrosis factor alpha-mediated apoptosis very early after virus inoculation and that pp65 contained in apoptotic cells came from the delivery of the matrix protein into the cell. |
2000-11-20 |
2023-08-12 |
human |
| M C Warren, E A Bump, D Medeiros, S J Braunhu. Oxidative stress-induced apoptosis of endothelial cells. Free radical biology & medicine. vol 29. issue 6. 2000-11-17. PMID:11025197. |
analysis of the events leading up to the first peak of apoptosis indicated that specific matrix metalloproteinases (mmps) were activated, suggesting that mmps may be involved in initiating the apoptotic process. |
2000-11-17 |
2023-08-12 |
Not clear |
| A M Mirza, A D Kohn, R A Roth, M McMaho. Oncogenic transformation of cells by a conditionally active form of the protein kinase Akt/PKB. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. vol 11. issue 6. 2000-11-02. PMID:10910095. |
consistent with these observations, activation of m+ akt:er* suppressed the apoptosis of rat1 cells that occurs after the detachment of these cells from extracellular matrix. |
2000-11-02 |
2023-08-12 |
Not clear |
| A M Loening, I E James, M E Levenston, A M Badger, E H Frank, B Kurz, M E Nuttall, H H Hung, S M Blake, A J Grodzinsky, M W Lar. Injurious mechanical compression of bovine articular cartilage induces chondrocyte apoptosis. Archives of biochemistry and biophysics. vol 381. issue 2. 2000-10-31. PMID:11032407. |
a bovine cartilage explant system was used to evaluate the effects of injurious compression on chondrocyte apoptosis and matrix biochemical and biomechanical properties within intact cartilage. |
2000-10-31 |
2023-08-12 |
cattle |
| A M Loening, I E James, M E Levenston, A M Badger, E H Frank, B Kurz, M E Nuttall, H H Hung, S M Blake, A J Grodzinsky, M W Lar. Injurious mechanical compression of bovine articular cartilage induces chondrocyte apoptosis. Archives of biochemistry and biophysics. vol 381. issue 2. 2000-10-31. PMID:11032407. |
while chondrocyte apoptosis may therefore be one of the earliest responses to tissue injury, it is currently unclear whether this initial cellular response subsequently drives cartilage matrix degradation and changes in the biomechanical properties of the tissue. |
2000-10-31 |
2023-08-12 |
cattle |