Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
P K Sha. Plaque disruption and thrombosis: potential role of inflammation and infection. Cardiology in review. vol 8. issue 1. 2001-04-05. PMID:11174871. |
inflammation with accumulation of activated mononuclear cells may play a potential role in plaque disruption through the elaboration of proteases, such as matrix degrading neutral metalloproteinases and other proteases, inhibition of function and/or survival, or promotion of apoptosis of matrix synthesizing smooth muscle cells. |
2001-04-05 |
2023-08-12 |
Not clear |
D R Hurst, H Li, X Xu, V L Badisa, Y E Shi, Q X San. Development and characterization of a new polyclonal antibody specifically against tissue inhibitor of metalloproteinases 4 in human breast cancer. Biochemical and biophysical research communications. vol 281. issue 1. 2001-04-05. PMID:11178975. |
tissue inhibitors of metalloproteinases (timps) may regulate extracellular matrix turnover and cellular functions by modulating matrix metalloproteinase (mmp) activity and cell proliferation and apoptosis. |
2001-04-05 |
2023-08-12 |
human |
Y Ibuki, R Got. Suppression of apoptosis by UVB irradiation: survival signaling via PI3-kinase/Akt pathway. Biochemical and biophysical research communications. vol 279. issue 3. 2001-03-29. PMID:11162442. |
however, we report here that uvb irradiation prevents induction of apoptosis in cells detached from the extracellular matrix under serum-free conditions. |
2001-03-29 |
2023-08-12 |
cattle |
Y Ibuki, R Got. Suppression of apoptosis by UVB irradiation: survival signaling via PI3-kinase/Akt pathway. Biochemical and biophysical research communications. vol 279. issue 3. 2001-03-29. PMID:11162442. |
nih3t3 cells cultured in bovine serum albumin-coated dishes (detached from the extracellular matrix) underwent apoptosis under serum-free conditions, which was inhibited by uvb (<0.1 j/cm(2)) irradiation, keeping suspension conditions, as determined by chromatin condensation and the appearance of a subg1 dna fraction. |
2001-03-29 |
2023-08-12 |
cattle |
D J Riley, S Thakker-Varia, F J Wilson, G J Poiani, C A Tozz. Role of proteolysis and apoptosis in regression of pulmonary vascular remodeling. Physiological research. vol 49. issue 5. 2001-03-22. PMID:11191362. |
we studied whether proteolysis of extracellular matrix proteins and apoptosis occur during reversal of remodeling produced by chronic hypoxia in the rat. |
2001-03-22 |
2023-08-12 |
rat |
D J Riley, S Thakker-Varia, F J Wilson, G J Poiani, C A Tozz. Role of proteolysis and apoptosis in regression of pulmonary vascular remodeling. Physiological research. vol 49. issue 5. 2001-03-22. PMID:11191362. |
our results suggest that activation of enzymes, which degrade matrix proteins, and apoptosis play a role in resolution of vascular remodeling. |
2001-03-22 |
2023-08-12 |
rat |
E Bonfoco, W Chen, R Paul, D A Cheresh, N R Coope. beta1 integrin antagonism on adherent, differentiated human neuroblastoma cells triggers an apoptotic signaling pathway. Neuroscience. vol 101. issue 4. 2001-03-01. PMID:11113363. |
integrin receptors mediate several functions including prevention of matrix detachment-induced apoptosis (anoikis) of several adherent cell types. |
2001-03-01 |
2023-08-12 |
human |
N Mitsiades, W H Yu, V Poulaki, M Tsokos, I Stamenkovi. Matrix metalloproteinase-7-mediated cleavage of Fas ligand protects tumor cells from chemotherapeutic drug cytotoxicity. Cancer research. vol 61. issue 2. 2001-02-22. PMID:11212252. |
in the present work, we addressed the involvement of the fasl/fas signaling pathway in doxorubicin-induced apoptosis and the ability of matrix metalloproteinases (mmps) to proteolytically cleave fasl in tumor cells. |
2001-02-22 |
2023-08-12 |
Not clear |
H Ishihara, H Yoshimoto, M Fujioka, R Murakami, A Hirano, T Fujii, A Ohtsuru, H Namba, S Yamashit. Keloid fibroblasts resist ceramide-induced apoptosis by overexpression of insulin-like growth factor I receptor. The Journal of investigative dermatology. vol 115. issue 6. 2001-02-15. PMID:11121143. |
our results suggest that keloid fibroblasts overexpressing insulin-like growth factor i receptor are resistant to apoptosis, thus allowing persistent proliferation and production of excessive extracellular matrix. |
2001-02-15 |
2023-08-12 |
Not clear |
I Rahman, W MacNe. Oxidative stress and regulation of glutathione in lung inflammation. The European respiratory journal. vol 16. issue 3. 2001-02-08. PMID:11028671. |
recent findings have suggested that gsh is important in immune modulation, remodelling of the extracellular matrix, apoptosis and mitochondrial respiration. |
2001-02-08 |
2023-08-12 |
human |
K A Lozoya, J B Flore. A novel rat osteoarthrosis model to assess apoptosis and matrix degradation. Pathology, research and practice. vol 196. issue 11. 2001-02-08. PMID:11186168. |
a novel rat osteoarthrosis model to assess apoptosis and matrix degradation. |
2001-02-08 |
2023-08-12 |
rat |
K A Lozoya, J B Flore. A novel rat osteoarthrosis model to assess apoptosis and matrix degradation. Pathology, research and practice. vol 196. issue 11. 2001-02-08. PMID:11186168. |
matrix degradation and apoptosis are two crucial features of osteoarthrosis (oa), but the relationship between them needs to be clarified. |
2001-02-08 |
2023-08-12 |
rat |
K A Lozoya, J B Flore. A novel rat osteoarthrosis model to assess apoptosis and matrix degradation. Pathology, research and practice. vol 196. issue 11. 2001-02-08. PMID:11186168. |
our results suggest that apoptosis could be involved in matrix degradation and that tunel might be a good method for spotting early apoptotic changes which, combined with careful morphological examinations, provide substantial help in improving apoptosis detection. |
2001-02-08 |
2023-08-12 |
rat |
J D Not. Adherence to osteopontin via alphavbeta3 suppresses phorbol ester-mediated apoptosis in MCF-7 breast cancer cells that overexpress protein kinase C-alpha. International journal of oncology. vol 17. issue 6. 2001-02-01. PMID:11078811. |
when adhered to osteopontin, a bone matrix protein, mcf-7-pkc-alpha cells were resistant to phorbol ester mediated apoptosis. |
2001-02-01 |
2023-08-12 |
mouse |
J R Dynlacht, M Earles, J Henthorn, J D Sen. Different patterns of DNA fragmentation and degradation of nuclear matrix proteins during apoptosis induced by radiation, hyperthermia or etoposide. Radiation research. vol 154. issue 5. 2001-01-25. PMID:11025648. |
different patterns of dna fragmentation and degradation of nuclear matrix proteins during apoptosis induced by radiation, hyperthermia or etoposide. |
2001-01-25 |
2023-08-12 |
Not clear |
J R Dynlacht, M Earles, J Henthorn, J D Sen. Different patterns of DNA fragmentation and degradation of nuclear matrix proteins during apoptosis induced by radiation, hyperthermia or etoposide. Radiation research. vol 154. issue 5. 2001-01-25. PMID:11025648. |
several nuclear matrix proteins are substrates for proteolytic cleavage during apoptosis. |
2001-01-25 |
2023-08-12 |
Not clear |
J R Dynlacht, M Earles, J Henthorn, J D Sen. Different patterns of DNA fragmentation and degradation of nuclear matrix proteins during apoptosis induced by radiation, hyperthermia or etoposide. Radiation research. vol 154. issue 5. 2001-01-25. PMID:11025648. |
using western blotting, the temporal patterns of cleavage of three nuclear matrix proteins (lamin b, numa and the nucleoporin tpr) were compared in hl60 cells induced to undergo apoptosis after irradiation, heat shock or treatment with etoposide. |
2001-01-25 |
2023-08-12 |
Not clear |
R Leonardi, L Villari, C Piacentini, G Bernasconi, U Baciliero, S Traval. CD44 standard form (CD44H) expression and distribution in dysfunctional human temporomandibular joint discs. International journal of oral and maxillofacial surgery. vol 29. issue 4. 2001-01-25. PMID:11030403. |
the up-regulation of cd44h observed in some dysfunctional tmj discs seems to indicate a prevention of apoptosis in fibroblastlike cells and an important role in phenotypical change of fibrochondrocytes into chondroblastlike cells, enabling the aggregation of chondroid tissue pericellular matrix components. |
2001-01-25 |
2023-08-12 |
human |
S Schweyer, B Hemmerlein, H J Radzun, A Fayyaz. Continuous recruitment, co-expression of tumour necrosis factor-alpha and matrix metalloproteinases, and apoptosis of macrophages in gout tophi. Virchows Archiv : an international journal of pathology. vol 437. issue 5. 2001-01-25. PMID:11147175. |
continuous recruitment, co-expression of tumour necrosis factor-alpha and matrix metalloproteinases, and apoptosis of macrophages in gout tophi. |
2001-01-25 |
2023-08-12 |
Not clear |
M Varedi, E E Tredget, A Ghahary, P G Scot. Stress-relaxation and contraction of a collagen matrix induces expression of TGF-beta and triggers apoptosis in dermal fibroblasts. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 78. issue 4. 2001-01-18. PMID:11012081. |
stress-relaxation and contraction of a collagen matrix induces expression of tgf-beta and triggers apoptosis in dermal fibroblasts. |
2001-01-18 |
2023-08-12 |
human |