| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N I Kozlova, G E Morozevich, A N Chubukina, A E Berma. Integrin alphavbeta3 promotes anchorage-dependent apoptosis in human intestinal carcinoma cells. Oncogene. vol 20. issue 34. 2001-08-23. PMID:11498793. |
this finding suggested that alphav-integrin generates a signal stimulating apoptosis of caco-2 cells upon their detachment from the extracellular matrix. |
2001-08-23 |
2023-08-12 |
human |
| M Jüllig, S Eriksso. Apoptosis induces efflux of the mitochondrial matrix enzyme deoxyguanosine kinase. The Journal of biological chemistry. vol 276. issue 26. 2001-08-16. PMID:11294860. |
apoptosis induces efflux of the mitochondrial matrix enzyme deoxyguanosine kinase. |
2001-08-16 |
2023-08-12 |
human |
| M Jüllig, S Eriksso. Apoptosis induces efflux of the mitochondrial matrix enzyme deoxyguanosine kinase. The Journal of biological chemistry. vol 276. issue 26. 2001-08-16. PMID:11294860. |
the redistribution of dgk from the mitochondria to the cytosol may be of importance for the activation of apoptotic purine nucleoside cofactors such as datp and demonstrates that mitochondrial matrix proteins may selectively leak out during apoptosis. |
2001-08-16 |
2023-08-12 |
human |
| Y Nakamura, K Sato, N Wakimoto, F Kimura, A Okuyama, K Motoyosh. A new matrix metalloproteinase inhibitor SI-27 induces apoptosis in several human myeloid leukemia cell lines and enhances sensitivity to TNF alpha-induced apoptosis. Leukemia. vol 15. issue 8. 2001-08-16. PMID:11480563. |
a new matrix metalloproteinase inhibitor si-27 induces apoptosis in several human myeloid leukemia cell lines and enhances sensitivity to tnf alpha-induced apoptosis. |
2001-08-16 |
2023-08-12 |
human |
| J Bode, C Benham, E Ernst, A Knopp, R Marschalek, R Strick, P Strisse. Fatal connections: when DNA ends meet on the nuclear matrix. Journal of cellular biochemistry. Supplement. vol Suppl 35. 2001-08-09. PMID:11389527. |
then we review the different dna targets of recombination, and present recent evidence implicating the nuclear matrix in processes which can induce either repair, translocation, deletion, or apoptosis. |
2001-08-09 |
2023-08-12 |
human |
| b' V Lallemand-Breitenbach, J Zhu, F Puvion, M Koken, N Honor\\xc3\\xa9, A Doubeikovsky, E Duprez, P P Pandolfi, E Puvion, P Freemont, H de Th\\xc3\\xa. Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation. The Journal of experimental medicine. vol 193. issue 12. 2001-08-09. PMID:11413191.' |
promyelocytic leukemia (pml) is the organizer of nuclear matrix domains, pml nuclear bodies (nbs), with a proposed role in apoptosis control. |
2001-08-09 |
2023-08-12 |
Not clear |
| R Snoeck, G Andrei, E De Clerc. Cidofovir in the treatment of HPV-associated lesions. Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie. vol 63. issue 2. 2001-08-02. PMID:11436421. |
different parameters of apoptosis, i.e., (i) induction of cpp32 (caspase-3) protease activity, (ii) translocation of phosphatidylserine (ps) from the inner part of the plasma membrane to the outer layer, (iii) disintegration of the nuclear matrix protein (nmp), (iv) dna fragmentation, (v) number of cells in apoptotic phase following cell cycle analysis, showed that the mechanism of cell death following treatment with cdv is based on apoptosis. |
2001-08-02 |
2023-08-12 |
human |
| H Tohge, K Tsutsui, K Sano, S Isik, K Tsutsu. High incidence of antinuclear antibodies that recognize the matrix attachment region. Biochemical and biophysical research communications. vol 285. issue 1. 2001-08-02. PMID:11437373. |
recent studies suggest that nuclear matrix is altered in the process of apoptosis and presented to the immune system, leading to the production of autoantibodies against its protein components. |
2001-08-02 |
2023-08-12 |
human |
| D Proudfoot, J N Skepper, L Hegyi, A Farzaneh-Far, C M Shanahan, P L Weissber. The role of apoptosis in the initiation of vascular calcification. Zeitschrift fur Kardiologie. vol 90 Suppl 3. 2001-07-26. PMID:11374032. |
these observations suggest that apoptosis is involved in the development of vsmc calcification and that vsmc-derived abs have similarities with matrix vesicles. |
2001-07-26 |
2023-08-12 |
human |
| M Poppe, C Reimertz, H Düssmann, A J Krohn, C M Luetjens, D Böckelmann, A L Nieminen, D Kögel, J H Preh. Dissipation of potassium and proton gradients inhibits mitochondrial hyperpolarization and cytochrome c release during neural apoptosis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 13. 2001-07-26. PMID:11426445. |
our data suggest two distinct mechanisms for mitochondrial cytochrome c release: (1) active cytochrome c release associated with early mitochondrial hyperpolarization, leading to neuronal apoptosis, and (2) passive cytochrome c release secondary to mitochondrial depolarization and matrix swelling. |
2001-07-26 |
2023-08-12 |
human |
| R R Fogelholm, A V Alh. Smoking and intervertebral disc degeneration. Medical hypotheses. vol 56. issue 4. 2001-07-19. PMID:11339862. |
ischemia, apoptosis, faulty synthesis of disc macromolecules, and an imbalance between disc matrix proteinases and their inhibitors may be involved in the pathogenesis of disc degeneration. |
2001-07-19 |
2023-08-12 |
Not clear |
| J Dimberg, A Hugander, A Sirsj. Decreased levels of precursor transforming growth factor beta1 in human colorectal cancer. International journal of molecular medicine. vol 7. issue 6. 2001-07-19. PMID:11351271. |
transforming growth factor (tgf) beta1 is a growth factor with wide-ranging effects on proliferation, differentiation, immunosuppression, apoptosis and matrix remodelling. |
2001-07-19 |
2023-08-12 |
human |
| T L Woodward, A S Mienaltowski, R R Modi, J M Bennett, S Z Hasla. Fibronectin and the alpha(5)beta(1) integrin are under developmental and ovarian steroid regulation in the normal mouse mammary gland. Endocrinology. vol 142. issue 7. 2001-07-19. PMID:11416044. |
extracellular matrix (ecm) proteins have been shown to regulate mammary epithelial cell proliferation, differentiation, and apoptosis in vitro. |
2001-07-19 |
2023-08-12 |
mouse |
| C S Adams, K Mansfield, R L Perlot, I M Shapir. Matrix regulation of skeletal cell apoptosis. Role of calcium and phosphate ions. The Journal of biological chemistry. vol 276. issue 23. 2001-07-12. PMID:11278303. |
matrix regulation of skeletal cell apoptosis. |
2001-07-12 |
2023-08-12 |
Not clear |
| C S Adams, K Mansfield, R L Perlot, I M Shapir. Matrix regulation of skeletal cell apoptosis. Role of calcium and phosphate ions. The Journal of biological chemistry. vol 276. issue 23. 2001-07-12. PMID:11278303. |
previously, we noted that inorganic phosphate (p(i)), a major component of bone extracellular matrix, induced osteoblast apoptosis (meleti, z., shapiro, i. m., and adams, c. s. (2000) bone (ny) 27, 359-366). |
2001-07-12 |
2023-08-12 |
Not clear |
| A Frankel, K Rosen, J Filmus, R S Kerbe. Induction of anoikis and suppression of human ovarian tumor growth in vivo by down-regulation of Bcl-X(L). Cancer research. vol 61. issue 12. 2001-07-12. PMID:11406560. |
normal or immortal epithelial cells are sensitive to a form of apoptosis, commonly referred to as anoikis, which is induced by detachment from the extracellular matrix (ecm). |
2001-07-12 |
2023-08-12 |
mouse |
| S J Fortunato, R Meno. Distinct molecular events suggest different pathways for preterm labor and premature rupture of membranes. American journal of obstetrics and gynecology. vol 184. issue 7. 2001-07-12. PMID:11408859. |
this study was designed to determine differences between preterm labor and preterm premature rupture of membranes by using molecular markers of extracellular matrix degradation and apoptosis. |
2001-07-12 |
2023-08-12 |
Not clear |
| M H Barcellos-Hoff, K B Ewa. Transforming growth factor-beta and breast cancer: Mammary gland development. Breast cancer research : BCR. vol 2. issue 2. 2001-07-05. PMID:11250698. |
transforming growth factor (tgf)-beta1 is a pluripotent cytokine that profoundly inhibits epithelial proliferation, induces apoptosis, and influences morphogenesis by mediating extracellular matrix deposition and remodeling. |
2001-07-05 |
2023-08-12 |
Not clear |
| K Hishikawa, B S Oemar, T Nakak. Static pressure regulates connective tissue growth factor expression in human mesangial cells. The Journal of biological chemistry. vol 276. issue 20. 2001-07-05. PMID:11278731. |
high levels of ctgf in turn enhance extracellular matrix production and induce apoptosis in mesangial cells, and may contribute to remodeling of mesangium and ultimately glomerulosclerosis. |
2001-07-05 |
2023-08-12 |
human |
| S Niland, A Cremer, J Fluck, J A Eble, T Krieg, S Sollber. Contraction-dependent apoptosis of normal dermal fibroblasts. The Journal of investigative dermatology. vol 116. issue 5. 2001-07-05. PMID:11348456. |
further, apoptosis in a mechanically relaxed collagen matrix could be abrogated by depolymerization of f-actin using cytochalasin d and also by disturbing actin-myosin interaction using 2,3-butanedione monoxime, indicating a possible dependence of apoptosis on mechanical forces and/or cell shape. |
2001-07-05 |
2023-08-12 |
human |