| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K M Yamada, M Arak. Tumor suppressor PTEN: modulator of cell signaling, growth, migration and apoptosis. Journal of cell science. vol 114. issue Pt 13. 2002-01-17. PMID:11559746. |
pten appears to play particularly important roles in regulating anoikis (apoptosis of cells after loss of contact with extracellular matrix) and cell migration. |
2002-01-17 |
2023-08-12 |
human |
| J Kim, H Wu, L Hawthorne, S Rafii, J Laurenc. Endothelial cell apoptotic genes associated with the pathogenesis of thrombotic microangiopathies: an application of oligonucleotide genechip technology. Microvascular research. vol 62. issue 2. 2002-01-14. PMID:11516238. |
additional differences suggest the importance of pathways related to the death receptor ligand trail, as well as a role for disruption of ec-extracellular matrix interactions in the initiation of apoptosis. |
2002-01-14 |
2023-08-12 |
human |
| Y Lu, R Zhou, S Zhang, X Jian. The cellular and molecular mechanism of laminin-glycopeptides on anti-metastasis. Chinese medical journal. vol 113. issue 5. 2002-01-14. PMID:11776108. |
to further study the anti-metastasis mechanism of laminin-glycopeptides on carcinoma cell proliferation, apoptosis and the secretion of matrix metalloproteinases. |
2002-01-14 |
2023-08-12 |
Not clear |
| K Mitan. [Disease-related gene and tumor progression]. Nihon rinsho. Japanese journal of clinical medicine. vol 59. issue 12. 2002-01-10. PMID:11766332. |
the bcr/abl fusion gene shows several functions, including inhibition of adhesion to stroma cells and extracellular matrix, activation of mitogenic signalings, inhibition of apoptosis, and degradation of inhibitory proteins, and thereby causes transformation of hematopoietic progenitors. |
2002-01-10 |
2023-08-12 |
Not clear |
| M Rabinovitc. Pathobiology of pulmonary hypertension. Extracellular matrix. Clinics in chest medicine. vol 22. issue 3. 2002-01-09. PMID:11590839. |
studies are reviewed aimed at addressing the cellular and molecular programs that regulate the production of the extracellular matrix describing new ways to arrest proliferation and migration of smooth muscle cells and to induce apoptosis. |
2002-01-09 |
2023-08-12 |
Not clear |
| E Giannopoulou, P Katsoris, M Hatziapostolou, D Kardamakis, E Kotsaki, C Polytarchou, A Parthymou, S Papaioannou, E Papadimitrio. X-rays modulate extracellular matrix in vivo. International journal of cancer. vol 94. issue 5. 2002-01-03. PMID:11745464. |
our study demonstrates that x-rays induce an early apoptosis of cam cells, modulate the synthesis and deposition of extracellular matrix (ecm) proteins involved in regulating angiogenesis and affect angiogenesis induced by tumour cells implanted onto the cam. |
2002-01-03 |
2023-08-12 |
chicken |
| J M Hock, V Krishnan, J E Onyia, J P Bidwell, J Milas, D Stanislau. Osteoblast apoptosis and bone turnover. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 16. issue 6. 2001-12-20. PMID:11393794. |
in reviewing factors regulating apoptosis in the postnatal skeleton, we discuss roles of cytokines, growth factors, members of the tnf pathway, and the extracellular matrix (ecm). |
2001-12-20 |
2023-08-12 |
Not clear |
| J Ratajczak, M Majka, J Kijowski, M Baj, Z K Pan, L A Marquez, A Janowska-Wieczorek, M Z Ratajcza. Biological significance of MAPK, AKT and JAK-STAT protein activation by various erythropoietic factors in normal human early erythroid cells. British journal of haematology. vol 115. issue 1. 2001-12-19. PMID:11722433. |
the activation of these signal transduction pathways was further correlated with various biological effects such as (i) cell proliferation, (ii) inhibition of apoptosis, (iii) activation of adhesion and (iv) secretion of the matrix metalloproteinases (mmps) mmp-9 and mmp-2, and vascular endothelial growth factor (vegf). |
2001-12-19 |
2023-08-12 |
human |
| F Kuchenbauer, U Hopfner, J Stalla, E Arzt, G K Stalla, M Páez-Pered. Extracellular matrix components regulate ACTH production and proliferation in corticotroph tumor cells. Molecular and cellular endocrinology. vol 175. issue 1-2. 2001-12-13. PMID:11325524. |
the extracellular matrix (ecm) conveys signals through membrane receptors called integrins producing changes in cell morphology, proliferation, differentiation and apoptosis. |
2001-12-13 |
2023-08-12 |
Not clear |
| S A Kopecky, M C Willingham, D S Lyle. Matrix protein and another viral component contribute to induction of apoptosis in cells infected with vesicular stomatitis virus. Journal of virology. vol 75. issue 24. 2001-12-13. PMID:11711608. |
matrix protein and another viral component contribute to induction of apoptosis in cells infected with vesicular stomatitis virus. |
2001-12-13 |
2023-08-12 |
Not clear |
| M L Jin, P Zhang, M X Ding, J P Yun, P F Chen, Y H Chen, Y Q Che. Altered expression of nuclear matrix proteins in etoposide induced apoptosis in HL-60 cells. Cell research. vol 11. issue 2. 2001-12-07. PMID:11453544. |
altered expression of nuclear matrix proteins in etoposide induced apoptosis in hl-60 cells. |
2001-12-07 |
2023-08-12 |
Not clear |
| J Carracedo, R Ramírez, A Martín-Malo, M Rodríguez, J A Madueño, P Aljam. Role of adhesion molecules in mononuclear cell apoptosis induced by cuprophan hemodialysis membranes. Nephron. vol 89. issue 2. 2001-12-07. PMID:11549901. |
interactions between adhesion molecules and extracellular matrix have been implicated in cell activation, proliferation, and/or apoptosis. |
2001-12-07 |
2023-08-12 |
Not clear |
| J Kijowski, M Baj-Krzyworzeka, M Majka, R Reca, L A Marquez, M Christofidou-Solomidou, A Janowska-Wieczorek, M Z Ratajcza. The SDF-1-CXCR4 axis stimulates VEGF secretion and activates integrins but does not affect proliferation and survival in lymphohematopoietic cells. Stem cells (Dayton, Ohio). vol 19. issue 5. 2001-12-07. PMID:11553854. |
we evaluated the phosphorylation of mapk p42/44, akt, and stat proteins and examined the ability of the ligands for these receptors (stromal-derived factor-1 [sdf-1] and macrophage inflammatory protein-1beta [mip-1beta]) to influence cell growth, apoptosis, adhesion, and production of vascular endothelial growth factors (vegf), matrix metalloproteinases (mmps) and their tissue inhibitors (timps) in these cell lines. |
2001-12-07 |
2023-08-12 |
human |
| D G Stupack, X S Puente, S Boutsaboualoy, C M Storgard, D A Cheres. Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins. The Journal of cell biology. vol 155. issue 3. 2001-12-07. PMID:11684710. |
here, we demonstrate that cells adherent within a three-dimensional extracellular matrix undergo apoptosis due to expression of unligated integrins, the beta subunit cytoplasmic domain, or its membrane proximal sequence kllitihdrkef. |
2001-12-07 |
2023-08-12 |
Not clear |
| B Wielockx, K Lannoy, S D Shapiro, T Itoh, S Itohara, J Vandekerckhove, C Liber. Inhibition of matrix metalloproteinases blocks lethal hepatitis and apoptosis induced by tumor necrosis factor and allows safe antitumor therapy. Nature medicine. vol 7. issue 11. 2001-12-07. PMID:11689884. |
inhibition of matrix metalloproteinases blocks lethal hepatitis and apoptosis induced by tumor necrosis factor and allows safe antitumor therapy. |
2001-12-07 |
2023-08-12 |
mouse |
| B Wielockx, K Lannoy, S D Shapiro, T Itoh, S Itohara, J Vandekerckhove, C Liber. Inhibition of matrix metalloproteinases blocks lethal hepatitis and apoptosis induced by tumor necrosis factor and allows safe antitumor therapy. Nature medicine. vol 7. issue 11. 2001-12-07. PMID:11689884. |
in a mouse model of lethal hepatitis induced by tnf, apoptosis and necrosis of hepatocytes, but also lethality, hypothermia and influx of leukocytes into the liver, are prevented by a broad-spectrum matrix metalloproteinase (mmp) inhibitor, bb-94. |
2001-12-07 |
2023-08-12 |
mouse |
| D Henrion, N Kubis, B I Lév. Physiological and pathophysiological functions of the AT(2) subtype receptor of angiotensin II: from large arteries to the microcirculation. Hypertension (Dallas, Tex. : 1979). vol 38. issue 5. 2001-12-07. PMID:11711513. |
in vitro at(2)r stimulation clearly inhibits cardiac and vascular smooth muscle growth and proliferation, stimulates apoptosis, and promotes extra cellular matrix synthesis. |
2001-12-07 |
2023-08-12 |
Not clear |
| E Seema. Unresolved issues in osteoporosis in men. Reviews in endocrine & metabolic disorders. vol 2. issue 1. 2001-12-05. PMID:11704979. |
if the reduced bone formation is most important, is this due to reduced osteoprogenitors, reduced osteoblast matrix synthesis or early osteoblast apoptosis? |
2001-12-05 |
2023-08-12 |
Not clear |
| K Rosen, M L Coll, A Li, J Filmu. Transforming growth factor-alpha prevents detachment-induced inhibition of c-Src kinase activity, Bcl-XL down-regulation, and apoptosis of intestinal epithelial cells. The Journal of biological chemistry. vol 276. issue 40. 2001-12-04. PMID:11487584. |
detachment of epithelial cells from the extracellular matrix (ecm) results in apoptosis, a phenomenon often referred to as anoikis. |
2001-12-04 |
2023-08-12 |
rat |
| H A Multhaupt, J C Alvarez, P A Rafferty, M J Warhol, R D Lackma. Fluoroquinolone's effect on growth of human chondrocytes and chondrosarcomas. In vitro and in vivo correlation. The Journal of bone and joint surgery. American volume. vol 83-A Suppl 2. issue Pt 1. 2001-12-04. PMID:11685846. |
the specimens were characterized morphologically with use of conventional light microscopy, electron microscopy, and immunohistochemistry to identify extracellular matrix, cell proliferation, and apoptosis. |
2001-12-04 |
2023-08-12 |
human |