| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Emmanouil Chavakis, Stefanie Dimmele. Regulation of endothelial cell survival and apoptosis during angiogenesis. Arteriosclerosis, thrombosis, and vascular biology. vol 22. issue 6. 2002-07-03. PMID:12067894. |
in this review, we focus on the regulation of ec survival and apoptosis during angiogenesis and especially on the effects and intracellular signaling promoted by angiogenic growth factors, endogenous angiogenic inhibitors (such as angiostatin, endostatin, and thrombospondin-1), and the adhesion to the extracellular matrix. |
2002-07-03 |
2023-08-12 |
Not clear |
| Jianguo Gu, Akemi Fujibayashi, Kenneth M Yamada, Kiyotoshi Sekiguch. Laminin-10/11 and fibronectin differentially prevent apoptosis induced by serum removal via phosphatidylinositol 3-kinase/Akt- and MEK1/ERK-dependent pathways. The Journal of biological chemistry. vol 277. issue 22. 2002-07-02. PMID:11891225. |
cell adhesion to the extracellular matrix inhibits apoptosis, but the molecular mechanisms underlying the signals transduced by different matrix components are not well understood. |
2002-07-02 |
2023-08-12 |
Not clear |
| Umesh M Hanumegowda, Barbara M Judy, Wade V Welshons, Chada S Redd. Selective inhibition of murine palatal mesenchymal cell proliferation in vitro by secalonic acid D. Toxicological sciences : an official journal of the Society of Toxicology. vol 66. issue 1. 2002-06-25. PMID:11861983. |
since reduced proliferation, increased apoptosis, and/or decreased extracellular matrix (ecm) synthesis of palatal mesenchymal cells (pmc) can all contribute to smaller shelf size, the hypothesis that teratogenically relevant concentrations (0 to 120 microg/ml) of sad will have adverse effects on one or more of these cellular processes was tested, using primary murine pmc cultures. |
2002-06-25 |
2023-08-12 |
mouse |
| Lillian Shum, Glen Nuckoll. The life cycle of chondrocytes in the developing skeleton. Arthritis research. vol 4. issue 2. 2002-06-20. PMID:11879545. |
extracellular growth and differentiation factors including bone morphogenetic proteins, fibroblast growth factors, parathyroid hormone-related peptide, extracellular matrix components, and members of the hedgehog and wnt families provide important signals for the regulation of cell proliferation, differentiation and apoptosis. |
2002-06-20 |
2023-08-12 |
Not clear |
| Marc Desforges, Geneviève Despars, Stéphane Bérard, Myriam Gosselin, Margie O McKenzie, Douglas S Lyles, Pierre J Talbot, Laurent Poliqui. Matrix protein mutations contribute to inefficient induction of apoptosis leading to persistent infection of human neural cells by vesicular stomatitis virus. Virology. vol 295. issue 1. 2002-06-20. PMID:12033766. |
matrix protein mutations contribute to inefficient induction of apoptosis leading to persistent infection of human neural cells by vesicular stomatitis virus. |
2002-06-20 |
2023-08-12 |
human |
| Satohiko Araki, Shinako Masuda, Hiroki Maeda, Miao Jun Ying, Hiroshi Hayash. Involvement of specific integrins in apoptosis induced by vascular apoptosis-inducing protein 1. Toxicon : official journal of the International Society on Toxinology. vol 40. issue 5. 2002-06-18. PMID:11821125. |
since other various metalloproteases and disintegrins in snake venoms are known to influence extracellular matrix and cell adhesion, we investigated here the involvement of these adhesion molecules in vap1-induced apoptosis. |
2002-06-18 |
2023-08-12 |
Not clear |
| Satohiko Araki, Shinako Masuda, Hiroki Maeda, Miao Jun Ying, Hiroshi Hayash. Involvement of specific integrins in apoptosis induced by vascular apoptosis-inducing protein 1. Toxicon : official journal of the International Society on Toxinology. vol 40. issue 5. 2002-06-18. PMID:11821125. |
consequently, vap1 induced apoptosis without degrading extracellular matrix or inhibiting adhesion of vec. |
2002-06-18 |
2023-08-12 |
Not clear |
| Satohiko Araki, Shinako Masuda, Hiroki Maeda, Miao Jun Ying, Hiroshi Hayash. Involvement of specific integrins in apoptosis induced by vascular apoptosis-inducing protein 1. Toxicon : official journal of the International Society on Toxinology. vol 40. issue 5. 2002-06-18. PMID:11821125. |
these results suggest that integrins are involved in vap1-induced apoptosis by some specific role rather than that of adhesion to extracellular matrix. |
2002-06-18 |
2023-08-12 |
Not clear |
| Robert L Perlot, Irving M Shapiro, Kyle Mansfield, Christopher S Adam. Matrix regulation of skeletal cell apoptosis II: role of Arg-Gly-Asp-containing peptides. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 17. issue 1. 2002-06-17. PMID:11771671. |
matrix regulation of skeletal cell apoptosis ii: role of arg-gly-asp-containing peptides. |
2002-06-17 |
2023-08-12 |
mouse |
| Robert L Perlot, Irving M Shapiro, Kyle Mansfield, Christopher S Adam. Matrix regulation of skeletal cell apoptosis II: role of Arg-Gly-Asp-containing peptides. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 17. issue 1. 2002-06-17. PMID:11771671. |
results of the investigation support the view that resorption of the extracellular matrix generates peptide products that can induce apoptosis of vicinal cells. |
2002-06-17 |
2023-08-12 |
mouse |
| Norbert Schuster, Kerstin Krieglstei. Mechanisms of TGF-beta-mediated apoptosis. Cell and tissue research. vol 307. issue 1. 2002-06-12. PMID:11810309. |
transforming growth factor-beta (tgf-beta) is a multifunctional cytokine, whose numerous cell and tissue activities include cell-cycle control, the regulation of early development, differentiation, extracellular matrix formation, hematopoesis, angiogenesis, chemotaxis, immune functions, and the induction of apoptosis. |
2002-06-12 |
2023-08-12 |
Not clear |
| Inmaculada Segura, Antonio Serrano, Gonzalo González De Buitrago, Manuel A González, Jose Luis Abad, Cristina Clavería, Lucio Gómez, Antonio Bernad, Carlos Martínez-A, Hans H Ries. Inhibition of programmed cell death impairs in vitro vascular-like structure formation and reduces in vivo angiogenesis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 16. issue 8. 2002-06-07. PMID:12039865. |
caspase inhibitors blocked vegf- or bfgf-induced huvec angiogenesis on 2- or 3-d collagen gels, respectively, confirming that apoptosis was not the result of nonspecific cell death after seeding on the matrix. |
2002-06-07 |
2023-08-12 |
human |
| G Gibson, D L Lin, X Wang, L Zhan. The release and activation of transforming growth factor beta2 associated with apoptosis of chick hypertrophic chondrocytes. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 16. issue 12. 2002-06-03. PMID:11760849. |
release of tgf-beta2 by chondrocytes at a late stage of their terminal differentiation and its activation in association with apoptosis may provide a mechanism controlling the processes of vascular invasion of growth cartilage and the deposition of bone matrix on nearby cartilage remnants. |
2002-06-03 |
2023-08-12 |
chicken |
| A Mobasheri, S D Carter, P Martín-Vasallo, M Shakibae. Integrins and stretch activated ion channels; putative components of functional cell surface mechanoreceptors in articular chondrocytes. Cell biology international. vol 26. issue 1. 2002-05-20. PMID:11779216. |
in this hypothesis paper we propose a chondrocyte mechanoreceptor model incorporating key extracellular matrix macromolecules, integrins, mechanosensitive ion channels, the cytoskeleton and subcellular signal transduction pathways that maintain the chondrocyte phenotype, prevent chondrocyte apoptosis and regulate chondrocyte-specific gene expression. |
2002-05-20 |
2023-08-12 |
Not clear |
| Joseph Mattana, Sergei Kochlatyi, Nora Gibbon. Metal-catalyzed oxidation of extracellular matrix proteins promotes human mesangial cell apoptosis and is associated with enhanced expression of Bax and caspase activation. Biochemical and biophysical research communications. vol 292. issue 3. 2002-05-16. PMID:11922616. |
metal-catalyzed oxidation of extracellular matrix proteins promotes human mesangial cell apoptosis and is associated with enhanced expression of bax and caspase activation. |
2002-05-16 |
2023-08-12 |
human |
| Joseph Mattana, Sergei Kochlatyi, Nora Gibbon. Metal-catalyzed oxidation of extracellular matrix proteins promotes human mesangial cell apoptosis and is associated with enhanced expression of Bax and caspase activation. Biochemical and biophysical research communications. vol 292. issue 3. 2002-05-16. PMID:11922616. |
in this study we evaluated whether oxidation of extracellular matrix could modulate human mesangial cell apoptosis. |
2002-05-16 |
2023-08-12 |
human |
| Joseph Mattana, Sergei Kochlatyi, Nora Gibbon. Metal-catalyzed oxidation of extracellular matrix proteins promotes human mesangial cell apoptosis and is associated with enhanced expression of Bax and caspase activation. Biochemical and biophysical research communications. vol 292. issue 3. 2002-05-16. PMID:11922616. |
cells on oxidized matrix demonstrated enhanced expression of bax, increased fragmentation of parp, and diminished apoptosis in the presence of the interleukin-1 beta converting enzyme inhibitor ac-tyr-val-ala-asp-aldehyde. |
2002-05-16 |
2023-08-12 |
human |
| Joseph Mattana, Sergei Kochlatyi, Nora Gibbon. Metal-catalyzed oxidation of extracellular matrix proteins promotes human mesangial cell apoptosis and is associated with enhanced expression of Bax and caspase activation. Biochemical and biophysical research communications. vol 292. issue 3. 2002-05-16. PMID:11922616. |
these data suggest that oxidation of extracellular matrix proteins may enhance human mesangial cell apoptosis via a mechanism that appears to involve enhanced expression of bax and caspase activation. |
2002-05-16 |
2023-08-12 |
human |
| Amedeo Lonardo, Paola Lori. Of liver, whisky and plants: a requiem for colchicine in alcoholic cirrhosis? European journal of gastroenterology & hepatology. vol 14. issue 4. 2002-05-15. PMID:11943945. |
in the future, preventive/therapeutic strategies will include campaigns to decrease alcohol abuse aimed at subjects genetically prone to develop alcoholic liver injury, prevention of liver fibrosis via inhibition of the na+/h+ exchange, stimulation of apoptosis of stellate cells, antagonism of cytokines involved in liver injury, degradation of extracellular matrix, and reversal of ethanol-induced inflammatory and fibrotic changes via increased nitric oxide levels. |
2002-05-15 |
2023-08-12 |
human |
| Zane S Jackson, Avrum I Gotlieb, B Lowell Langill. Wall tissue remodeling regulates longitudinal tension in arteries. Circulation research. vol 90. issue 8. 2002-05-14. PMID:11988494. |
also, increased rates of apoptosis were indicated by degradation of dna into oligonucleosomes, and matrix remodeling was reflected in enlarged fenestrae in the internal elastic lamina and increased expression and activation of gelatinases, especially matrix metalloproteinase-2. |
2002-05-14 |
2023-08-12 |
rabbit |