| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Delphine Javelaud, Marie-France Poupon, Juana Wietzerbin, Françoise Besanço. Inhibition of constitutive NF-kappa B activity suppresses tumorigenicity of Ewing sarcoma EW7 cells. International journal of cancer. vol 98. issue 2. 2002-03-07. PMID:11857407. |
it causes, however, a remarkable loss of their ability to generate tumors in nude mice that correlates with both a decrease in extracellular matrix (ecm) protein secretion and an acquisition of sensitivity to murine tumor necrosis factor alpha (tnf alpha)-induced apoptosis. |
2002-03-07 |
2023-08-12 |
mouse |
| J R Berenso. Advances in the biology and treatment of myeloma bone disease. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. vol 58 Suppl 3. 2002-02-26. PMID:11757204. |
possible mechanisms include inducing apoptosis in tumor cells, inhibiting angiogenesis, and reducing adherence of cancer cells to the bone matrix. |
2002-02-26 |
2023-08-12 |
Not clear |
| E P Moiseev. Adhesion receptors of vascular smooth muscle cells and their functions. Cardiovascular research. vol 52. issue 3. 2002-02-19. PMID:11738054. |
many functions of smcs, such as adhesion, migration, proliferation, contraction, differentiation and apoptosis are determined by surface adhesion receptors involved in cell-cell binding and interactions between cells and extracellular matrix (ecm) proteins. |
2002-02-19 |
2023-08-12 |
Not clear |
| N Mitsiades, V Poulaki, C S Mitsiades, K C Anderso. Induction of tumour cell apoptosis by matrix metalloproteinase inhibitors: new tricks from a (not so) old drug. Expert opinion on investigational drugs. vol 10. issue 6. 2002-02-14. PMID:11772236. |
induction of tumour cell apoptosis by matrix metalloproteinase inhibitors: new tricks from a (not so) old drug. |
2002-02-14 |
2023-08-12 |
human |
| Z Zhang, X M Yuan, L H Li, F P Xi. Transdifferentiation of neoplastic cells. Medical hypotheses. vol 57. issue 5. 2002-02-13. PMID:11735329. |
tumor cell transdifferentiation may be influenced or determined by cellular genetic instabilities, proliferation and apoptosis, as well as by extracellular matrix and growth factors. |
2002-02-13 |
2023-08-12 |
Not clear |
| M Yasuda, Y Tanaka, K Fujii, K Yasumot. CD44 stimulation down-regulates Fas expression and Fas-mediated apoptosis of lung cancer cells. International immunology. vol 13. issue 10. 2002-02-07. PMID:11581176. |
based on these findings, we postulate a new concept--that interaction of cd44 on lung cancer cells with fragments of extracellular hyaluronan present in the surrounding extracellular matrix reduces fas expression as well as fas-mediated apoptosis of cancer cells. |
2002-02-07 |
2023-08-12 |
Not clear |
| Carla Boccaccio, Margherita Ando', Paolo M Comogli. A differentiation switch for genetically modified hepatocytes. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 16. issue 1. 2002-01-31. PMID:11709498. |
this process, defined as "branching morphogenesis," involves cell scatter and redistribution to form ramified hollow tubules within the extracellular matrix, and protection from apoptosis. |
2002-01-31 |
2023-08-12 |
mouse |
| N Yamaguchi, I R Kieba, J Korostoff, P S Howard, B J Shenker, E T Lall. Maintenance of oxidative phosphorylation protects cells from Actinobacillus actinomycetemcomitans leukotoxin-induced apoptosis. Cellular microbiology. vol 3. issue 12. 2002-01-31. PMID:11736993. |
the results indicate that ltx induces apoptosis through a mitochondrial pathway that involves decreased levels of the adp in the mitochondrial matrix, a lack of substrate for atp synthetase and arrest of oxidative phosphorylation. |
2002-01-31 |
2023-08-12 |
Not clear |
| H A Kim, D I Suh, Y W Son. Relationship between chondrocyte apoptosis and matrix depletion in human articular cartilage. The Journal of rheumatology. vol 28. issue 9. 2002-01-30. PMID:11550972. |
relationship between chondrocyte apoptosis and matrix depletion in human articular cartilage. |
2002-01-30 |
2023-08-12 |
human |
| H A Kim, D I Suh, Y W Son. Relationship between chondrocyte apoptosis and matrix depletion in human articular cartilage. The Journal of rheumatology. vol 28. issue 9. 2002-01-30. PMID:11550972. |
since matrix degradation is important in the pathology of arthritis, we investigated the effect of matrix depletion on chondrocyte apoptosis. |
2002-01-30 |
2023-08-12 |
human |
| D A Flusberg, Y Numaguchi, D E Ingbe. Cooperative control of Akt phosphorylation, bcl-2 expression, and apoptosis by cytoskeletal microfilaments and microtubules in capillary endothelial cells. Molecular biology of the cell. vol 12. issue 10. 2002-01-22. PMID:11598193. |
this ability of the cytoskeleton to control capillary endothelial cell survival may be important for understanding the relationship among extracellular matrix turnover, cell shape changes, and apoptosis during angiogenesis inhibition. |
2002-01-22 |
2023-08-12 |
Not clear |
| K M Yamada, M Arak. Tumor suppressor PTEN: modulator of cell signaling, growth, migration and apoptosis. Journal of cell science. vol 114. issue Pt 13. 2002-01-17. PMID:11559746. |
pten appears to play particularly important roles in regulating anoikis (apoptosis of cells after loss of contact with extracellular matrix) and cell migration. |
2002-01-17 |
2023-08-12 |
human |
| J Kim, H Wu, L Hawthorne, S Rafii, J Laurenc. Endothelial cell apoptotic genes associated with the pathogenesis of thrombotic microangiopathies: an application of oligonucleotide genechip technology. Microvascular research. vol 62. issue 2. 2002-01-14. PMID:11516238. |
additional differences suggest the importance of pathways related to the death receptor ligand trail, as well as a role for disruption of ec-extracellular matrix interactions in the initiation of apoptosis. |
2002-01-14 |
2023-08-12 |
human |
| Y Lu, R Zhou, S Zhang, X Jian. The cellular and molecular mechanism of laminin-glycopeptides on anti-metastasis. Chinese medical journal. vol 113. issue 5. 2002-01-14. PMID:11776108. |
to further study the anti-metastasis mechanism of laminin-glycopeptides on carcinoma cell proliferation, apoptosis and the secretion of matrix metalloproteinases. |
2002-01-14 |
2023-08-12 |
Not clear |
| K Mitan. [Disease-related gene and tumor progression]. Nihon rinsho. Japanese journal of clinical medicine. vol 59. issue 12. 2002-01-10. PMID:11766332. |
the bcr/abl fusion gene shows several functions, including inhibition of adhesion to stroma cells and extracellular matrix, activation of mitogenic signalings, inhibition of apoptosis, and degradation of inhibitory proteins, and thereby causes transformation of hematopoietic progenitors. |
2002-01-10 |
2023-08-12 |
Not clear |
| M Rabinovitc. Pathobiology of pulmonary hypertension. Extracellular matrix. Clinics in chest medicine. vol 22. issue 3. 2002-01-09. PMID:11590839. |
studies are reviewed aimed at addressing the cellular and molecular programs that regulate the production of the extracellular matrix describing new ways to arrest proliferation and migration of smooth muscle cells and to induce apoptosis. |
2002-01-09 |
2023-08-12 |
Not clear |
| E Giannopoulou, P Katsoris, M Hatziapostolou, D Kardamakis, E Kotsaki, C Polytarchou, A Parthymou, S Papaioannou, E Papadimitrio. X-rays modulate extracellular matrix in vivo. International journal of cancer. vol 94. issue 5. 2002-01-03. PMID:11745464. |
our study demonstrates that x-rays induce an early apoptosis of cam cells, modulate the synthesis and deposition of extracellular matrix (ecm) proteins involved in regulating angiogenesis and affect angiogenesis induced by tumour cells implanted onto the cam. |
2002-01-03 |
2023-08-12 |
chicken |
| J M Hock, V Krishnan, J E Onyia, J P Bidwell, J Milas, D Stanislau. Osteoblast apoptosis and bone turnover. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 16. issue 6. 2001-12-20. PMID:11393794. |
in reviewing factors regulating apoptosis in the postnatal skeleton, we discuss roles of cytokines, growth factors, members of the tnf pathway, and the extracellular matrix (ecm). |
2001-12-20 |
2023-08-12 |
Not clear |
| J Ratajczak, M Majka, J Kijowski, M Baj, Z K Pan, L A Marquez, A Janowska-Wieczorek, M Z Ratajcza. Biological significance of MAPK, AKT and JAK-STAT protein activation by various erythropoietic factors in normal human early erythroid cells. British journal of haematology. vol 115. issue 1. 2001-12-19. PMID:11722433. |
the activation of these signal transduction pathways was further correlated with various biological effects such as (i) cell proliferation, (ii) inhibition of apoptosis, (iii) activation of adhesion and (iv) secretion of the matrix metalloproteinases (mmps) mmp-9 and mmp-2, and vascular endothelial growth factor (vegf). |
2001-12-19 |
2023-08-12 |
human |
| F Kuchenbauer, U Hopfner, J Stalla, E Arzt, G K Stalla, M Páez-Pered. Extracellular matrix components regulate ACTH production and proliferation in corticotroph tumor cells. Molecular and cellular endocrinology. vol 175. issue 1-2. 2001-12-13. PMID:11325524. |
the extracellular matrix (ecm) conveys signals through membrane receptors called integrins producing changes in cell morphology, proliferation, differentiation and apoptosis. |
2001-12-13 |
2023-08-12 |
Not clear |