| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Robert L Perlot, Irving M Shapiro, Kyle Mansfield, Christopher S Adam. Matrix regulation of skeletal cell apoptosis II: role of Arg-Gly-Asp-containing peptides. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 17. issue 1. 2002-06-17. PMID:11771671. |
results of the investigation support the view that resorption of the extracellular matrix generates peptide products that can induce apoptosis of vicinal cells. |
2002-06-17 |
2023-08-12 |
mouse |
| Norbert Schuster, Kerstin Krieglstei. Mechanisms of TGF-beta-mediated apoptosis. Cell and tissue research. vol 307. issue 1. 2002-06-12. PMID:11810309. |
transforming growth factor-beta (tgf-beta) is a multifunctional cytokine, whose numerous cell and tissue activities include cell-cycle control, the regulation of early development, differentiation, extracellular matrix formation, hematopoesis, angiogenesis, chemotaxis, immune functions, and the induction of apoptosis. |
2002-06-12 |
2023-08-12 |
Not clear |
| Inmaculada Segura, Antonio Serrano, Gonzalo González De Buitrago, Manuel A González, Jose Luis Abad, Cristina Clavería, Lucio Gómez, Antonio Bernad, Carlos Martínez-A, Hans H Ries. Inhibition of programmed cell death impairs in vitro vascular-like structure formation and reduces in vivo angiogenesis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 16. issue 8. 2002-06-07. PMID:12039865. |
caspase inhibitors blocked vegf- or bfgf-induced huvec angiogenesis on 2- or 3-d collagen gels, respectively, confirming that apoptosis was not the result of nonspecific cell death after seeding on the matrix. |
2002-06-07 |
2023-08-12 |
human |
| G Gibson, D L Lin, X Wang, L Zhan. The release and activation of transforming growth factor beta2 associated with apoptosis of chick hypertrophic chondrocytes. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 16. issue 12. 2002-06-03. PMID:11760849. |
release of tgf-beta2 by chondrocytes at a late stage of their terminal differentiation and its activation in association with apoptosis may provide a mechanism controlling the processes of vascular invasion of growth cartilage and the deposition of bone matrix on nearby cartilage remnants. |
2002-06-03 |
2023-08-12 |
chicken |
| A Mobasheri, S D Carter, P Martín-Vasallo, M Shakibae. Integrins and stretch activated ion channels; putative components of functional cell surface mechanoreceptors in articular chondrocytes. Cell biology international. vol 26. issue 1. 2002-05-20. PMID:11779216. |
in this hypothesis paper we propose a chondrocyte mechanoreceptor model incorporating key extracellular matrix macromolecules, integrins, mechanosensitive ion channels, the cytoskeleton and subcellular signal transduction pathways that maintain the chondrocyte phenotype, prevent chondrocyte apoptosis and regulate chondrocyte-specific gene expression. |
2002-05-20 |
2023-08-12 |
Not clear |
| Joseph Mattana, Sergei Kochlatyi, Nora Gibbon. Metal-catalyzed oxidation of extracellular matrix proteins promotes human mesangial cell apoptosis and is associated with enhanced expression of Bax and caspase activation. Biochemical and biophysical research communications. vol 292. issue 3. 2002-05-16. PMID:11922616. |
metal-catalyzed oxidation of extracellular matrix proteins promotes human mesangial cell apoptosis and is associated with enhanced expression of bax and caspase activation. |
2002-05-16 |
2023-08-12 |
human |
| Joseph Mattana, Sergei Kochlatyi, Nora Gibbon. Metal-catalyzed oxidation of extracellular matrix proteins promotes human mesangial cell apoptosis and is associated with enhanced expression of Bax and caspase activation. Biochemical and biophysical research communications. vol 292. issue 3. 2002-05-16. PMID:11922616. |
in this study we evaluated whether oxidation of extracellular matrix could modulate human mesangial cell apoptosis. |
2002-05-16 |
2023-08-12 |
human |
| Joseph Mattana, Sergei Kochlatyi, Nora Gibbon. Metal-catalyzed oxidation of extracellular matrix proteins promotes human mesangial cell apoptosis and is associated with enhanced expression of Bax and caspase activation. Biochemical and biophysical research communications. vol 292. issue 3. 2002-05-16. PMID:11922616. |
cells on oxidized matrix demonstrated enhanced expression of bax, increased fragmentation of parp, and diminished apoptosis in the presence of the interleukin-1 beta converting enzyme inhibitor ac-tyr-val-ala-asp-aldehyde. |
2002-05-16 |
2023-08-12 |
human |
| Joseph Mattana, Sergei Kochlatyi, Nora Gibbon. Metal-catalyzed oxidation of extracellular matrix proteins promotes human mesangial cell apoptosis and is associated with enhanced expression of Bax and caspase activation. Biochemical and biophysical research communications. vol 292. issue 3. 2002-05-16. PMID:11922616. |
these data suggest that oxidation of extracellular matrix proteins may enhance human mesangial cell apoptosis via a mechanism that appears to involve enhanced expression of bax and caspase activation. |
2002-05-16 |
2023-08-12 |
human |
| Amedeo Lonardo, Paola Lori. Of liver, whisky and plants: a requiem for colchicine in alcoholic cirrhosis? European journal of gastroenterology & hepatology. vol 14. issue 4. 2002-05-15. PMID:11943945. |
in the future, preventive/therapeutic strategies will include campaigns to decrease alcohol abuse aimed at subjects genetically prone to develop alcoholic liver injury, prevention of liver fibrosis via inhibition of the na+/h+ exchange, stimulation of apoptosis of stellate cells, antagonism of cytokines involved in liver injury, degradation of extracellular matrix, and reversal of ethanol-induced inflammatory and fibrotic changes via increased nitric oxide levels. |
2002-05-15 |
2023-08-12 |
human |
| Zane S Jackson, Avrum I Gotlieb, B Lowell Langill. Wall tissue remodeling regulates longitudinal tension in arteries. Circulation research. vol 90. issue 8. 2002-05-14. PMID:11988494. |
also, increased rates of apoptosis were indicated by degradation of dna into oligonucleosomes, and matrix remodeling was reflected in enlarged fenestrae in the internal elastic lamina and increased expression and activation of gelatinases, especially matrix metalloproteinase-2. |
2002-05-14 |
2023-08-12 |
rabbit |
| Frank R Murphy, Razao Issa, Xiaoying Zhou, Shabna Ratnarajah, Hideaki Nagase, Michael J P Arthur, Christopher Benyon, John P Iredal. Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition: implications for reversibility of liver fibrosis. The Journal of biological chemistry. vol 277. issue 13. 2002-05-10. PMID:11796725. |
inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition: implications for reversibility of liver fibrosis. |
2002-05-10 |
2023-08-12 |
Not clear |
| C C Wykoff, C W Pugh, A L Harris, P H Maxwell, P J Ratcliff. The HIF pathway: implications for patterns of gene expression in cancer. Novartis Foundation symposium. vol 240. 2002-05-09. PMID:11727931. |
in addition to known hif target genes involved in angiogenesis, glucose metabolism and vasomotor control, these new targets include examples with functions in matrix metabolism, apoptosis, carbon dioxide metabolism and secondary cascades of transcriptional control. |
2002-05-09 |
2023-08-12 |
Not clear |
| Eugene Kissin, Joseph H Kor. Apoptosis and myofibroblasts in the pathogenesis of systemic sclerosis. Current rheumatology reports. vol 4. issue 2. 2002-05-08. PMID:11890878. |
tissue fibrosis is the result of a complex series of events focusing on regulation of fibroblast proliferation, synthesis of extracellular matrix, and apoptosis. |
2002-05-08 |
2023-08-12 |
Not clear |
| Victor M Bondar, David J McConke. Anoikis is regulated by BCL-2-independent pathways in human prostate carcinoma cells. The Prostate. vol 51. issue 1. 2002-05-08. PMID:11920957. |
loss of contact with the extracellular matrix (ecm) triggers a specialized form of apoptosis known as "anoikis" in normal epithelial cells. |
2002-05-08 |
2023-08-12 |
human |
| Y Feng, L Y Wang, T Cai, J W Jin, G F Zhou, L H Cao, X L Zh. All-trans-retinoic acid increased the expression of integrin alpha5beta1 and induced "anoikis" in SMMC-7721 hepatocarcinoma cell. Journal of experimental & clinical cancer research : CR. vol 20. issue 3. 2002-05-02. PMID:11718225. |
it is extensively shown that integrin can regulate various cellular functions, including apoptosis, probably by contributing to signal transduction processes through interaction with extracellular matrix (ecm) proteins. |
2002-05-02 |
2023-08-12 |
Not clear |
| K Johnson, K Pritzker, J Goding, R Terkeltau. The nucleoside triphosphate pyrophosphohydrolase isozyme PC-1 directly promotes cartilage calcification through chondrocyte apoptosis and increased calcium precipitation by mineralizing vesicles. The Journal of rheumatology. vol 28. issue 12. 2002-05-02. PMID:11764218. |
increased chondrocyte apoptosis and expression of annexin v occur at sites of matrix calcification in degenerative arthritis, and membrane limited chondrocyte apoptotic bodies containing ntppph may promote chondrocalcinosis by acting as mineralizing matrix vesicles (mv). |
2002-05-02 |
2023-08-12 |
Not clear |
| Belgin Selam, Umit A Kayisli, Juan A Garcia-Velasco, Aydin Aric. Extracellular matrix-dependent regulation of Fas ligand expression in human endometrial stromal cells. Biology of reproduction. vol 66. issue 1. 2002-04-23. PMID:11751256. |
induction of fasl expression by adhesion of endometrial stromal cells to the extracellular matrix may take part in the development of a relative immunotolerance by inducing apoptosis of cytotoxic t lymphocytes, which will allow further development of ectopic implants. |
2002-04-23 |
2023-08-12 |
human |
| Guenadi Kouniavsky, Marat Khaikin, Isabel Zvibel, Dov Zippel, Shlomo Brill, Zamir Halpern, Moshe Pap. Stromal extracellular matrix reduces chemotherapy-induced apoptosis in colon cancer cell lines. Clinical & experimental metastasis. vol 19. issue 1. 2002-04-22. PMID:11918083. |
stromal extracellular matrix reduces chemotherapy-induced apoptosis in colon cancer cell lines. |
2002-04-22 |
2023-08-12 |
human |
| Guenadi Kouniavsky, Marat Khaikin, Isabel Zvibel, Dov Zippel, Shlomo Brill, Zamir Halpern, Moshe Pap. Stromal extracellular matrix reduces chemotherapy-induced apoptosis in colon cancer cell lines. Clinical & experimental metastasis. vol 19. issue 1. 2002-04-22. PMID:11918083. |
several studies have shown that extracellular matrix reduces chemotherapeutic drugs-induced apoptosis in small cell lung cancer cells, myelomas and gliomas. |
2002-04-22 |
2023-08-12 |
human |