| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H A Multhaupt, J C Alvarez, P A Rafferty, M J Warhol, R D Lackma. Fluoroquinolone's effect on growth of human chondrocytes and chondrosarcomas. In vitro and in vivo correlation. The Journal of bone and joint surgery. American volume. vol 83-A Suppl 2. issue Pt 1. 2001-12-04. PMID:11685846. |
the treated chondrocytes showed a decrease in cell proliferation, but there was no induction of apoptosis or effect on the expression of extracellular matrix proteins. |
2001-12-04 |
2023-08-12 |
human |
| M Akdis, A Trautmann, S Klunker, K Blaser, C A Akdi. Cytokine network and dysregulated apoptosis in atopic dermatitis. Acta odontologica Scandinavica. vol 59. issue 3. 2001-11-01. PMID:11501888. |
they are protected from apoptosis by cytokines such as il-2, il-4, and il-15 and extracellular matrix components such as fibronectin and transferrin. |
2001-11-01 |
2023-08-12 |
Not clear |
| S Endo, K Inada, Y Inoue, Y Yamada, Y Fujino, M Miura, E Baba, N Sato, G Wakabayashi, H Katsuya, S Sat. Nuclear matrix protein (NMP) levels in patients with acute pancreatitis. Journal of medicine. vol 31. issue 5-6. 2001-11-01. PMID:11508325. |
nuclear matrix protein (nmp) is an index of apoptosis. |
2001-11-01 |
2023-08-12 |
Not clear |
| J P Iredal. Hepatic stellate cell behavior during resolution of liver injury. Seminars in liver disease. vol 21. issue 3. 2001-11-01. PMID:11586470. |
recovery from acute and chronic injury is characterized by apoptosis of activated hscs, which removes extracellular matrix-producing cells that are also expressing timps, thereby relieving the inhibition of matrix degradation. |
2001-11-01 |
2023-08-12 |
Not clear |
| A Fraser, U Fearon, R Reece, P Emery, D J Veal. Matrix metalloproteinase 9, apoptosis, and vascular morphology in early arthritis. Arthritis and rheumatism. vol 44. issue 9. 2001-11-01. PMID:11592363. |
matrix metalloproteinase 9, apoptosis, and vascular morphology in early arthritis. |
2001-11-01 |
2023-08-12 |
Not clear |
| A Fraser, U Fearon, R Reece, P Emery, D J Veal. Matrix metalloproteinase 9, apoptosis, and vascular morphology in early arthritis. Arthritis and rheumatism. vol 44. issue 9. 2001-11-01. PMID:11592363. |
to examine matrix metalloproteinase 9 (mmp-9) in the synovial fluid (sf) and synovial membrane (sm) in relation to vascular endothelial cell (ec) apoptosis, vascular endothelial growth factor (vegf), and sm vascular pattern. |
2001-11-01 |
2023-08-12 |
Not clear |
| K Fujii, Y Fujii, S Hubscher, Y Tanak. CD44 is the physiological trigger of Fas up-regulation on rheumatoid synovial cells. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 3. 2001-10-25. PMID:11466334. |
based on these findings, we postulate a new concept: that interaction of cd44 on ra synovial cells with hyaluronan fragments present in the surrounding extracellular matrix augments fas expression as well as fas-mediated apoptosis of synovial cells. |
2001-10-25 |
2023-08-12 |
Not clear |
| K Inoue, C G Wood, J W Slaton, T Karashima, P Sweeney, C P Dinne. Adenoviral-mediated gene therapy of human bladder cancer with antisense interleukin-8. Oncology reports. vol 8. issue 5. 2001-10-25. PMID:11496299. |
ad il-8-as therapy decreased the in vivo expression of il-8 and matrix metalloproteinase type 9 (mmp-9), reduced microvessel density, and enhanced endothelial cell apoptosis. |
2001-10-25 |
2023-08-12 |
mouse |
| K T Webe. Cardioreparation in hypertensive heart disease. Hypertension (Dallas, Tex. : 1979). vol 38. issue 3 Pt 2. 2001-10-25. PMID:11566936. |
structural homogeneity of cardiac tissue is governed by a balanced equilibrium existing between stimulator and inhibitor signals that regulate cell growth, apoptosis, phenotype, and matrix turnover. |
2001-10-25 |
2023-08-12 |
Not clear |
| R E Bachelder, M A Wendt, N Fujita, T Tsuruo, A M Mercuri. The cleavage of Akt/protein kinase B by death receptor signaling is an important event in detachment-induced apoptosis. The Journal of biological chemistry. vol 276. issue 37. 2001-10-11. PMID:11463786. |
epithelial cells undergo death receptor-dependent apoptosis when detached from matrix, a process termed anoikis. |
2001-10-11 |
2023-08-12 |
Not clear |
| H van der Kuip, A W Goetz, C Miething, J Duyster, W E Aulitzk. Adhesion to fibronectin selectively protects Bcr-Abl+ cells from DNA damage-induced apoptosis. Blood. vol 98. issue 5. 2001-10-04. PMID:11520804. |
integrin-mediated adhesion to extracellular matrix molecules is critical for the regulation of growth and apoptosis. |
2001-10-04 |
2023-08-12 |
Not clear |
| R A Nowa. Identification of new therapies for leiomyomas: what in vitro studies can tell us. Clinical obstetrics and gynecology. vol 44. issue 2. 2001-09-20. PMID:11344996. |
these growth factors not only regulate the proliferation, apoptosis, and extra-cellular matrix production of the smcs but also regulate proliferation and migration of vascular endothelial cells. |
2001-09-20 |
2023-08-12 |
Not clear |
| R Chen, O Kim, J Yang, K Sato, K M Eisenmann, J McCarthy, H Chen, Y Qi. Regulation of Akt/PKB activation by tyrosine phosphorylation. The Journal of biological chemistry. vol 276. issue 34. 2001-09-20. PMID:11445557. |
these two yf mutants fail to block forkhead transcription factor activity in 293 cells and are unable to prevent apoptosis induced by matrix detachment. |
2001-09-20 |
2023-08-12 |
Not clear |
| M Jost, T M Huggett, C Kari, U Rodec. Matrix-independent survival of human keratinocytes through an EGF receptor/MAPK-kinase-dependent pathway. Molecular biology of the cell. vol 12. issue 5. 2001-09-13. PMID:11359940. |
normal epithelial cells undergo apoptosis when they are denied contact with the extracellular matrix, in a process termed "anoikis." |
2001-09-13 |
2023-08-12 |
human |
| F Aoudjit, K Vuor. Integrin signaling inhibits paclitaxel-induced apoptosis in breast cancer cells. Oncogene. vol 20. issue 36. 2001-09-13. PMID:11526484. |
in the present study, we demonstrate that in the mda-mb-231 and mda-mb-435 breast cancer cells, ligation of beta1 integrins by their extracellular matrix ligands inhibits significantly apoptosis induced by paclitaxel and vincristine, two microtubule-directed chemotherapeutic agents that are widely used in the therapy of breast cancer. |
2001-09-13 |
2023-08-12 |
Not clear |
| J A Davies, C E Fisher, M W Barnet. Glycosaminoglycans in the study of mammalian organ development. Biochemical Society transactions. vol 29. issue Pt 2. 2001-09-06. PMID:11356147. |
gags interact with a large number of proteins and can participate in matrix organization, cell adhesion, differentiation, growth and apoptosis. |
2001-09-06 |
2023-08-12 |
mouse |
| A Lesay, J A Hickman, R M Gibso. Disruption of focal adhesions mediates detachment during neuronal apoptosis. Neuroreport. vol 12. issue 10. 2001-09-06. PMID:11447317. |
the aim of this study was to investigate the mechanisms of detachment of neuronal cells from the extracellular matrix (ecm) during apoptosis. |
2001-09-06 |
2023-08-12 |
Not clear |
| A Gemma, K Takenaka, Y Hosoya, K Matuda, M Seike, F Kurimoto, Y Ono, K Uematsu, Y Takeda, S Hibino, A Yoshimura, M Shibuya, S Kudo. Altered expression of several genes in highly metastatic subpopulations of a human pulmonary adenocarcinoma cell line. European journal of cancer (Oxford, England : 1990). vol 37. issue 12. 2001-09-06. PMID:11506965. |
this analysis in subpopulations of a lung cancer cell line indicated that the highly metastatic potential of lung cancer may be induced not by an alteration in the expression of a single gene, but by the accumulation of alterations in the expression of several genes involved in extracellular matrix (ecm) adhesion disruption, ecm degradation, escape from apoptosis, and resistance to transforming growth factor-beta(1) (tgf-beta(1)). |
2001-09-06 |
2023-08-12 |
human |
| S M O'Connor, D A Stenger, K M Shaffer, W M. Survival and neurite outgrowth of rat cortical neurons in three-dimensional agarose and collagen gel matrices. Neuroscience letters. vol 304. issue 3. 2001-08-30. PMID:11343834. |
the results suggest that collagen, because it is a major extracellular matrix constituent, suppresses apoptosis and provides a suitable substrate for neuronal survival and differentiation. |
2001-08-30 |
2023-08-12 |
rat |
| A Rangarajan, R Syal, S Selvarajah, O Chakrabarti, A Sarin, S Krishn. Activated Notch1 signaling cooperates with papillomavirus oncogenes in transformation and generates resistance to apoptosis on matrix withdrawal through PKB/Akt. Virology. vol 286. issue 1. 2001-08-23. PMID:11448155. |
activated notch1 signaling cooperates with papillomavirus oncogenes in transformation and generates resistance to apoptosis on matrix withdrawal through pkb/akt. |
2001-08-23 |
2023-08-12 |
human |