| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Aoudjit, K Vuor. Matrix attachment regulates Fas-induced apoptosis in endothelial cells: a role for c-flip and implications for anoikis. The Journal of cell biology. vol 152. issue 3. 2001-05-24. PMID:11157988. |
these studies identify matrix attachment as a survival factor against death receptor-mediated apoptosis and provide a molecular mechanism for anoikis and previously observed fas resistance in endothelial cells. |
2001-05-24 |
2023-08-12 |
Not clear |
| A Schulze, K Lehmann, H B Jefferies, M McMahon, J Downwar. Analysis of the transcriptional program induced by Raf in epithelial cells. Genes & development. vol 15. issue 8. 2001-05-24. PMID:11316792. |
some of the most strongly induced genes encoded growth factors of the egf family: autocrine activation of the egf receptor was shown to be responsible for the ability of raf activation to protect these cells from apoptosis induced by detachment of cells from extracellular matrix (anoikis), which is a critical component of the transformed phenotype. |
2001-05-24 |
2023-08-12 |
human |
| G Pogány, F Timár, J Oláh, R Harisi, G Polony, S Paku, J Bocsi, A Jeney, G W Lauri. Role of the basement membrane in tumor cell dormancy and cytotoxic resistance. Oncology. vol 60. issue 3. 2001-05-24. PMID:11340380. |
to determine whether both are influenced by the extracellular milieu in which tumors reside, ht1080 human fibrosarcoma, mcf-7 breast carcinoma and oscort osteosarcoma cell proliferation, viability, apoptosis and cytoreductive-treatment-induced death were investigated in the presence or absence of extracellular matrix (ecm). |
2001-05-24 |
2023-08-12 |
human |
| Y H Kang, S J Chung, I J Kang, J H Park, R Bünge. Intramitochondrial pyruvate attenuates hydrogen peroxide-induced apoptosis in bovine pulmonary artery endothelium. Molecular and cellular biochemistry. vol 216. issue 1-2. 2001-05-21. PMID:11216862. |
since alpha-cyano-3-hydroxycinnamate re-distributed medium pyruvate and l-lactate consistent with selective blockade of pyruvate uptake into the mitochondria, the findings support the hypothesis that pyruvate protection against h2o2 apoptosis is mediated in part via the mitochondrial matrix compartment. |
2001-05-21 |
2023-08-12 |
cattle |
| S E Miller, R B Veal. Environmental modulation of alpha(v), alpha(2) and beta(1) integrin subunit expression in human oesophageal squamous cell carcinomas. Cell biology international. vol 25. issue 1. 2001-05-21. PMID:11237409. |
ectopic expression of integrins, characteristic of transformed cells, is instrumental in differentiation, proliferation, apoptosis, angiogenesis, matrix degradation and migration. |
2001-05-21 |
2023-08-12 |
human |
| X Han, Y Sun, S Scott, D Bleic. Tissue inhibitor of metalloproteinase-1 prevents cytokine-mediated dysfunction and cytotoxicity in pancreatic islets and beta-cells. Diabetes. vol 50. issue 5. 2001-05-21. PMID:11334407. |
in addition to inhibiting matrix metalloproteinase-2 and matrix metalloproteinase-9 activity, recent studies suggest that tissue inhibitor of metalloproteinase (timp)-1 may inhibit apoptosis in various cell lines. |
2001-05-21 |
2023-08-12 |
mouse |
| G Gazzanelli, F Luchetti, S Burattini, F Mannello, E Falcieri, S Pap. Matrix metalloproteinases expression in HL-60 promyelocytic leukemia cells during apoptosis. Apoptosis : an international journal on programmed cell death. vol 5. issue 2. 2001-05-03. PMID:11232244. |
matrix metalloproteinases expression in hl-60 promyelocytic leukemia cells during apoptosis. |
2001-05-03 |
2023-08-12 |
human |
| G Gazzanelli, F Luchetti, S Burattini, F Mannello, E Falcieri, S Pap. Matrix metalloproteinases expression in HL-60 promyelocytic leukemia cells during apoptosis. Apoptosis : an international journal on programmed cell death. vol 5. issue 2. 2001-05-03. PMID:11232244. |
these results suggest that in hl-60 cells the expression/release of matrix metalloproteases can be down-regulated in the presence of the apoptotic-induced alterations, and that the decreased matrix-degrading capacity of this leukemic cell line during apoptosis may reduce its invasive potential. |
2001-05-03 |
2023-08-12 |
human |
| C Daniel, J Duffield, T Brunner, K Steinmann-Niggli, N Lods, H P Mart. Matrix metalloproteinase inhibitors cause cell cycle arrest and apoptosis in glomerular mesangial cells. The Journal of pharmacology and experimental therapeutics. vol 297. issue 1. 2001-05-03. PMID:11259528. |
matrix metalloproteinase inhibitors cause cell cycle arrest and apoptosis in glomerular mesangial cells. |
2001-05-03 |
2023-08-12 |
rat |
| C Daniel, J Duffield, T Brunner, K Steinmann-Niggli, N Lods, H P Mart. Matrix metalloproteinase inhibitors cause cell cycle arrest and apoptosis in glomerular mesangial cells. The Journal of pharmacology and experimental therapeutics. vol 297. issue 1. 2001-05-03. PMID:11259528. |
we hypothesized that these features may be ameliorated by induction of cell cycle arrest and apoptosis as result of therapy with matrix metalloproteinase (mmp) inhibitors. |
2001-05-03 |
2023-08-12 |
rat |
| Z H Wang, D Yu, H K Li, V W Chow, C C Ng, H B Chan, S B Cheng, E C Che. Alteration of nuclear matrix protein composition of neuroblastoma cells after arsenic trioxide treatment. Anticancer research. vol 21. issue 1A. 2001-05-03. PMID:11299786. |
as early as 24 hours after as2o3 treatment, we began to observe the alteration of nuclear matrix proteins and apoptosis in tumor cells by tunel assay but not by dna ladder. |
2001-05-03 |
2023-08-12 |
mouse |
| Z H Wang, D Yu, H K Li, V W Chow, C C Ng, H B Chan, S B Cheng, E C Che. Alteration of nuclear matrix protein composition of neuroblastoma cells after arsenic trioxide treatment. Anticancer research. vol 21. issue 1A. 2001-05-03. PMID:11299786. |
our results also showed that before a mass range of apoptosis occurred, the composition of nuclear matrix proteins had altered. |
2001-05-03 |
2023-08-12 |
mouse |
| Z H Wang, D Yu, H K Li, V W Chow, C C Ng, H B Chan, S B Cheng, E C Che. Alteration of nuclear matrix protein composition of neuroblastoma cells after arsenic trioxide treatment. Anticancer research. vol 21. issue 1A. 2001-05-03. PMID:11299786. |
hence the alteration of nuclear matrix proteins, such as increased expression of hsc, may be a sensitive indicator for the detection of early apoptosis. |
2001-05-03 |
2023-08-12 |
mouse |
| C Jiang, Z Wang, H Ganther, J L. Caspases as key executors of methyl selenium-induced apoptosis (anoikis) of DU-145 prostate cancer cells. Cancer research. vol 61. issue 7. 2001-05-03. PMID:11306488. |
this process therefore resembled "anoikis," a special mode of apoptosis induction in which adherent cells lose contact with the extracellular matrix. |
2001-05-03 |
2023-08-12 |
human |
| C Wild-Bode, M Weller, A Rimner, J Dichgans, W Wic. Sublethal irradiation promotes migration and invasiveness of glioma cells: implications for radiotherapy of human glioblastoma. Cancer research. vol 61. issue 6. 2001-04-26. PMID:11289157. |
this hitherto unknown biological effect of irradiation is p53 independent, involves enhanced alphavbeta3 integrin expression, an altered profile of matrix metalloproteinase-2 and matrix metalloproteinase-9 (mmp-2 and mmp-9) expression and activity, altered membrane type 1 mmp and tissue inhibitor of metalloproteinases-2 expression, and an altered bcl-2/bax rheostat favoring resistance to apoptosis. |
2001-04-26 |
2023-08-12 |
human |
| F Silvestris, M Tucci, P Cafforio, F Dammacc. Fas-L up-regulation by highly malignant myeloma plasma cells: role in the pathogenesis of anemia and disease progression. Blood. vol 97. issue 5. 2001-04-19. PMID:11222356. |
these results strongly suggest that the deregulated apoptosis in myeloma clones plays an active role in the progressive destruction of the erythroid matrix by a cytotoxic mechanism based on up-regulation of fas-l. |
2001-04-19 |
2023-08-12 |
Not clear |
| A Reichert, N Heisterkamp, G Q Daley, J Groffe. Treatment of Bcr/Abl-positive acute lymphoblastic leukemia in P190 transgenic mice with the farnesyl transferase inhibitor SCH66336. Blood. vol 97. issue 5. 2001-04-19. PMID:11222386. |
this increase in activity leads to malignant transformation by interference with basic cellular functions such as the control of proliferation, adherence to stroma and extracellular matrix, and apoptosis. |
2001-04-19 |
2023-08-12 |
mouse |
| Y Zhao, M Wu, Y Shen, Z Zha. Analysis of nuclear apoptotic process in a cell-free system. Cellular and molecular life sciences : CMLS. vol 58. issue 2. 2001-04-19. PMID:11289311. |
we confirmed the results using whole-mount electron microscopy, and found that although the nuclear lamina was destroyed early, the nuclear matrix largely remained intact during the course of apoptosis. |
2001-04-19 |
2023-08-12 |
mouse |
| A W Eberhardt, A Yeager-Jones, H C Blai. Regional trabecular bone matrix degeneration and osteocyte death in femora of glucocorticoid- treated rabbits. Endocrinology. vol 142. issue 3. 2001-04-12. PMID:11181552. |
we conclude that exposure of bone matrix permeability and that regional cell death consistent with apoptosis is an early event in glucocorticoid-induced bone damage. |
2001-04-12 |
2023-08-12 |
Not clear |
| M X Wang, T B Gray, W C Park, P Prabhasawat, W Culbertson, R Forster, K Hanna, S C Tsen. Reduction in corneal haze and apoptosis by amniotic membrane matrix in excimer laser photoablation in rabbits. Journal of cataract and refractive surgery. vol 27. issue 2. 2001-04-12. PMID:11226800. |
reduction in corneal haze and apoptosis by amniotic membrane matrix in excimer laser photoablation in rabbits. |
2001-04-12 |
2023-08-12 |
human |