| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daqian Zhou, Chao Song, Yongliang Mei, Kang Cheng, Fei Liu, Weiye Cai, Silong Gao, Zhenlong Wang, Zongchao Li. A review of Duhuo Jisheng decoction mechanisms in intervertebral disc degeneration in vitro and animal studies. Journal of orthopaedic surgery and research. vol 18. issue 1. 2023-06-15. PMID:37322524. |
at present, we found that its mechanism of action mainly involves regulation of inflammatory factors, reduction of apoptosis and pyroptosis of npcs, inhibition of extracellular matrix degradation, improvement of intestinal flora, etc. |
2023-06-15 |
2023-08-14 |
Not clear |
| Jun Gu, Xiaoyang Zhou, Lin Xi. Significance of Oxidative Stress in the Diagnosis and Subtype Classification of Intervertebral Disc Degeneration. Biochemical genetics. 2023-06-14. PMID:37314550. |
intervertebral disc degeneration (ivdd) is a common illness of aging, and its pathophysiological process is mainly manifested by cell aging and apoptosis, an imbalance in the production and catabolism of extracellular matrix, and an inflammatory response. |
2023-06-14 |
2023-08-14 |
Not clear |
| Ilaria Bernabei, Uwe Hansen, Driss Ehirchiou, Jürgen Brinckmann, Veronique Chobaz, Nathalie Busso, Sonia Nas. CD11b Deficiency Favors Cartilage Calcification via Increased Matrix Vesicles, Apoptosis, and Lysyl Oxidase Activity. International journal of molecular sciences. vol 24. issue 11. 2023-06-11. PMID:37298730. |
cd11b deficiency favors cartilage calcification via increased matrix vesicles, apoptosis, and lysyl oxidase activity. |
2023-06-11 |
2023-08-14 |
mouse |
| Ilaria Bernabei, Uwe Hansen, Driss Ehirchiou, Jürgen Brinckmann, Veronique Chobaz, Nathalie Busso, Sonia Nas. CD11b Deficiency Favors Cartilage Calcification via Increased Matrix Vesicles, Apoptosis, and Lysyl Oxidase Activity. International journal of molecular sciences. vol 24. issue 11. 2023-06-11. PMID:37298730. |
mechanistically, we found more calcification-competent matrix vesicles and more apoptosis in both cartilage and chondrocytes isolated from cd11b-deficient mice. |
2023-06-11 |
2023-08-14 |
mouse |
| Huahui Yu, Xiaolu Jiao, Yunyun Yang, Qianwen Lv, Zhiyong Du, Linyi Li, Chaowei Hu, Yunhui Du, Jing Zhang, Fan Li, Qiuju Sun, Yu Wang, Dong Chen, Xiaoping Zhang, Yanwen Qi. ANGPTL8 Deletion Attenuates Abdominal Aortic Aneurysm Formation in ApoE-/- Mice. Clinical science (London, England : 1979). 2023-06-09. PMID:37294581. |
knockout of angptl8 significantly reduced angii-induced aaa formation, elastin breaks, aortic inflammatory cytokines, matrix metalloproteinase expression, and smooth muscle cell apoptosis in apoe-/- mice. |
2023-06-09 |
2023-08-14 |
mouse |
| Ritesh Urade, Wen-Tsan Chang, Ching-Chung Ko, Ruei-Nian Li, Hui-Min Yang, Hsuan-Yu Chen, Lin-Ya Huang, Meng-Yang Chang, Chang-Yi Wu, Chien-Chih Chi. A fluorene derivative inhibits human hepatocellular carcinoma cells by ROS-mediated apoptosis, anoikis and autophagy. Life sciences. 2023-06-09. PMID:37295712. |
along with elevated ros generation and apoptosis, msdf also caused anoikis and cell death by causing cells to lose contact with their extracellular matrix. |
2023-06-09 |
2023-08-14 |
human |
| Xiaokun Zhao, Jinghong Yuan, Jingyu Jia, Jian Zhang, Jiahao Liu, Qi Chen, Tao Li, Zhiwen Wu, Hui Wu, Xinxin Miao, Tianlong Wu, Bin Li, Xigao Chen. Role of non‑coding RNAs in cartilage endplate (Review). Experimental and therapeutic medicine. vol 26. issue 1. 2023-06-05. PMID:37273754. |
in addition, a summary of the current knowledge regarding the deregulation of ncrnas in idd in relation to their actions on cep cell functions, including cell proliferation, apoptosis and extracellular matrix synthesis/degradation is presented. |
2023-06-05 |
2023-08-14 |
Not clear |
| Yuting Tang, Fangling Hong, Siyang Ding, Jiashu Yang, Ming Zhang, Yunfei Ma, Que Zheng, Dawei Yang, Yucui Jin, Changyan M. METTL3-mediated m Cell reports. vol 42. issue 6. 2023-06-04. PMID:37270777. |
overexpression of igfbp7-ot significantly inhibits chondrocyte viability, promotes chondrocyte apoptosis, and reduces extracellular matrix components, whereas igfbp7-ot knockdown has the opposite effects. |
2023-06-04 |
2023-08-14 |
Not clear |
| Hong Su, Sheng-Yong Su, Pu Yang, Yan-Jun Guo, Jing L. [Progress of research on mechanisms of acupuncture and moxibustion in the treatment of rheumatoid arthritis]. Zhen ci yan jiu = Acupuncture research. vol 48. issue 5. 2023-05-29. PMID:37247865. |
), 4) regulating related signaling pathways (suppressing nuclear factor-kb/vascular endothelial growth factor, janus tyrosine kinase-signal transducer and activator of transcription, transient receptor potential vanilloid and canonical wnt/β-catenin pathways), and activating cholinergic anti-inflammatory pathway, 5) regulating histocyte energy metabolism (improving amino acid supply and reducing negative nitrogen balance to improve immune regulation function), 6) maintaining the balance of bone cells and articular cartilage (by regulating the balance between synthesis and degradation of articular cartilage matrix, and the balance of bone cells and osteoclasts), 7) up-regulating energy metabolism gene (atp50, atp6v1b2) expression and regulating biological rhythm gene (clock, per2, rev-erb) expression, 8) regulating mirnas-mediated chondrocyte apoptosis. |
2023-05-29 |
2023-08-14 |
Not clear |
| Argen Mamazhakypov, Abdirashit Maripov, Akpay S Sarybaev, Ralph Theo Schermuly, Akylbek Sydyko. Osteopontin in Pulmonary Hypertension. Biomedicines. vol 11. issue 5. 2023-05-27. PMID:37239056. |
osteopontin modulates a plethora of cellular processes within the pulmonary vasculature, including cell proliferation, migration, apoptosis, extracellular matrix synthesis, and inflammation via binding to various receptors such as integrins and cd44. |
2023-05-27 |
2023-08-14 |
Not clear |
| Maria Teresa Rocchetti, Francesco Bellanti, Mariia Zadorozhna, Daniela Fiocco, Domenica Mangier. Multi-Faceted Role of Luteolin in Cancer Metastasis: EMT, Angiogenesis, ECM Degradation and Apoptosis. International journal of molecular sciences. vol 24. issue 10. 2023-05-27. PMID:37240168. |
thus, the purpose of this review consists in highlighting the relevant mechanisms by which luteolin inhibits tumor progression in metastasis, i.e., affecting epithelial-mesenchymal transition (emt), repressing angiogenesis and lysis of extracellular matrix (ecm), as well as inducing apoptosis. |
2023-05-27 |
2023-08-14 |
human |
| b' Krist\\xc3\\xbdna Sl\\xc3\\xa1mov\\xc3\\xa1, Jakub \\xc4\\x8cerven\\xc3\\xbd, Zuzana M\\xc3\\xa9sz\\xc3\\xa1ros, Tereza Friede, David Vrbata, Vladim\\xc3\\xadr K\\xc5\\x99en, Pavla Bojarov\\xc3\\xa. Oligosaccharide Ligands of Galectin-4 and Its Subunits: Multivalency Scores Highly. Molecules (Basel, Switzerland). vol 28. issue 10. 2023-05-27. PMID:37241779.' |
galectins are carbohydrate-binding lectins that modulate the proliferation, apoptosis, adhesion, or migration of cells by cross-linking glycans on cell membranes or extracellular matrix components. |
2023-05-27 |
2023-08-14 |
Not clear |
| Yuan Yue, Jia-Qi Yang, Sheng-Yu Lu, Jun Ge, Hong-Yun Nie, Kai-Ge Liu, Fei Liu, Hao Li, Hong-Feng Yan, Tao Zhang, Pei-Ming Sun, Hong-Wei Sun, Jian-Wu Yang, Jin-Lian Zhou, Yan Cu. Simulated microgravity altered the proliferation, apoptosis, and extracellular matrix formation of L929 fibroblasts and the transforming growth factor-β1/Smad3 signaling pathway. Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI). vol 29. issue 5. 2023-05-26. PMID:37231921. |
simulated microgravity altered the proliferation, apoptosis, and extracellular matrix formation of l929 fibroblasts and the transforming growth factor-β1/smad3 signaling pathway. |
2023-05-26 |
2023-08-14 |
Not clear |
| Wenzhao Li, Cheng Tao, Minzhi Mao, Kewei Zh. The Nrf2/HMGB1/NF-κB axis modulates chondrocyte apoptosis and extracellular matrix degradation in osteoarthritis. Acta biochimica et biophysica Sinica. 2023-05-26. PMID:37232576. |
the nrf2/hmgb1/nf-κb axis modulates chondrocyte apoptosis and extracellular matrix degradation in osteoarthritis. |
2023-05-26 |
2023-08-14 |
Not clear |
| Ye Tian, Xinxi Li, Chao Bai, Zhenwei Yang, Lei Zhang, Jun Luo, Wenbin Zhan. lncRNA MIR503HG Targets miR-191-5p/PLCD1 Axis and Negatively Modulates Apoptosis, Extracellular Matrix Disruption, and Inflammation in Abdominal Aortic Aneurysm. Mediators of inflammation. vol 2023. 2023-05-25. PMID:37228901. |
lncrna mir503hg targets mir-191-5p/plcd1 axis and negatively modulates apoptosis, extracellular matrix disruption, and inflammation in abdominal aortic aneurysm. |
2023-05-25 |
2023-08-14 |
Not clear |
| Ye Tian, Xinxi Li, Chao Bai, Zhenwei Yang, Lei Zhang, Jun Luo, Wenbin Zhan. lncRNA MIR503HG Targets miR-191-5p/PLCD1 Axis and Negatively Modulates Apoptosis, Extracellular Matrix Disruption, and Inflammation in Abdominal Aortic Aneurysm. Mediators of inflammation. vol 2023. 2023-05-25. PMID:37228901. |
as the most prevalent subtype of aortic aneurysm, abdominal aortic aneurysm (aaa) features the apoptosis, extracellular matrix (ecm) disruption, and inflammation response of vascular smooth muscle cells (vsmcs). |
2023-05-25 |
2023-08-14 |
Not clear |
| Zhuang Li, Jun L. CircRNAs in osteoarthritis: research status and prospect. Frontiers in genetics. vol 14. 2023-05-25. PMID:37229197. |
many studies have found that circrnas play an essential role in the progression of oa, including extracellular matrix metabolism, autophagy, apoptosis, the proliferation of chondrocytes, inflammation, oxidative stress, cartilage development, and chondrogenic differentiation. |
2023-05-25 |
2023-08-14 |
Not clear |
| Haoran Wang, Zhongqing Wu, Kanna X. CKLF1 interference alleviates IL‑1β‑induced inflammation, apoptosis and degradation of the extracellular matrix in chondrocytes via CCR5. Experimental and therapeutic medicine. vol 25. issue 6. 2023-05-25. PMID:37229323. |
cklf1 interference alleviates il‑1β‑induced inflammation, apoptosis and degradation of the extracellular matrix in chondrocytes via ccr5. |
2023-05-25 |
2023-08-14 |
human |
| Bo Xiong, Lihua Chen, Yue Huang, Guanyu Lu, Cai Chen, Jiao Nong, Haida Pa. ZBTB16 eases lipopolysaccharide‑elicited inflammation, apoptosis and degradation of extracellular matrix in chondrocytes during osteoarthritis by suppressing GRK2 transcription. Experimental and therapeutic medicine. vol 25. issue 6. 2023-05-19. PMID:37206562. |
zbtb16 eases lipopolysaccharide‑elicited inflammation, apoptosis and degradation of extracellular matrix in chondrocytes during osteoarthritis by suppressing grk2 transcription. |
2023-05-19 |
2023-08-14 |
human |
| Li Yin, Weilu Gao, Hao Tang, Zongsheng Yi. BASP1 knockdown suppresses chondrocyte apoptosis and extracellular matrix degradation in vivo and in vitro: A possible therapeutic approach for osteoarthritis. Experimental cell research. 2023-05-19. PMID:37207971. |
basp1 knockdown suppresses chondrocyte apoptosis and extracellular matrix degradation in vivo and in vitro: a possible therapeutic approach for osteoarthritis. |
2023-05-19 |
2023-08-14 |
mouse |