| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R S Fife, B Stott, R E Car. Effects of a selective cyclooxygenase-2 inhibitor on cancer cells in vitro. Cancer biology & therapy. vol 3. issue 2. 2004-11-19. PMID:14726667. |
we now report on the effects of a selective cox-2 inhibitor, celecoxib, on cell proliferation, matrix metalloproteinase (mmp) concentration, angiogenesis using an in vitro assay, and apoptosis in several human cancer cell lines. |
2004-11-19 |
2023-08-12 |
human |
| M Mandel, M Gurevich, R Pauzner, N Kaminski, A Achiro. Autoimmunity gene expression portrait: specific signature that intersects or differentiates between multiple sclerosis and systemic lupus erythematosus. Clinical and experimental immunology. vol 138. issue 1. 2004-11-19. PMID:15373920. |
the autoimmune signature included genes that encode proteins involved in apoptosis, cell cycle, inflammation and regulation of matrix metalloproteinase pathways. |
2004-11-19 |
2023-08-12 |
human |
| b' Nevena Grdovi\\xc4\\x87, Goran Poznanovi\\xc4\\x8. Characterization of an Mg2+-dependent endonucleolytic activity of the rat hepatocyte nuclear matrix. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. vol 136. issue 3. 2004-11-16. PMID:14602157.' |
in view of its properties and preferential localization on the nuclear matrix, the endonuclease described herein could be a possible candidate that brings about initial dna cleavage during apoptosis. |
2004-11-16 |
2023-08-12 |
rat |
| Laura Hertel, Edward S Mocarsk. Global analysis of host cell gene expression late during cytomegalovirus infection reveals extensive dysregulation of cell cycle gene expression and induction of Pseudomitosis independent of US28 function. Journal of virology. vol 78. issue 21. 2004-11-16. PMID:15479839. |
cmv infection resulted in lower levels of transcripts encoding cytoskeletal, extracellular matrix, and adhesion proteins, together with small gtpases and apoptosis regulators, and in higher levels of transcripts encoding cell cycle, dna replication, energy production, and inflammation-related gene products. |
2004-11-16 |
2023-08-12 |
human |
| B Wappenschmidt, E Wardelmann, A Gehrig, T Schöndorf, N Maass, G Bonatz, A-M Gassel, T Pietsch, P Mallmann, B H F Weber, R K Schmutzle. PTEN mutations do not cause nuclear beta-catenin accumulation in endometrial carcinomas. Human pathology. vol 35. issue 10. 2004-11-10. PMID:15492994. |
pten encodes a dual-specificity phosphatase with lipid phosphatase and protein tyrosine phosphatase activities that regulate both apoptosis and interactions with the extracellular matrix. |
2004-11-10 |
2023-08-12 |
Not clear |
| D Kumar, D W Lundgren, R M Moore, R J Silver, J J Moor. Hydrogen peroxide induced apoptosis in amnion-derived WISH cells is not inhibited by vitamin C. Placenta. vol 25. issue 4. 2004-11-06. PMID:15028418. |
hp induced apoptosis in wish cells; as assessed by cytochrome-c release from mitochondria, poly-(adp-ribose)-polymerase (parp) cleavage, nuclear matrix protein (nmp) release and dna fragmentation analysis. |
2004-11-06 |
2023-08-12 |
Not clear |
| Yingpei Zhang, Catherine Haskins, Marisa Lopez-Cruzan, Jianhua Zhang, Victoria E Centonze, Brian Herma. Detection of mitochondrial caspase activity in real time in situ in live cells. Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. vol 10. issue 4. 2004-11-01. PMID:15327705. |
using a mitochondrially targeted cfp-caspase 3 substrate-yfp construct (mc3y), we demonstrate for the first time that there is caspase-3-like activity in the mitochondrial matrix of some cells at very late stage of apoptosis. |
2004-11-01 |
2023-08-12 |
Not clear |
| Paul S Brookes, Yisang Yoon, James L Robotham, M W Anders, Shey-Shing She. Calcium, ATP, and ROS: a mitochondrial love-hate triangle. American journal of physiology. Cell physiology. vol 287. issue 4. 2004-10-28. PMID:15355853. |
for example, mitochondrial matrix ca(2+) overload can lead to enhanced generation of reactive oxygen species, triggering of the permeability transition pore, and cytochrome c release, leading to apoptosis. |
2004-10-28 |
2023-08-12 |
Not clear |
| Soo-Mi Kweon, Zee-Won Lee, Sun-Ju Yi, Young-Myeong Kim, Jeong-A Han, Sang-Gi Paik, Skwon-Soo H. Protective role of tissue transglutaminase in the cell death induced by TNF-alpha in SH-SY5Y neuroblastoma cells. Journal of biochemistry and molecular biology. vol 37. issue 2. 2004-10-28. PMID:15469694. |
tissue transglutaminase (ttgase) regulates various biological processes, including extracellular matrix organization, cellular differentiation, and apoptosis. |
2004-10-28 |
2023-08-12 |
human |
| Se-Jin Chung, Se-Hee Lee, Yong-Jin Lee, Hyoung-Sook Park, Rolf Bünger, Young-Hee Kan. Pyruvate protection against endothelial cytotoxicity induced by blockade of glucose uptake. Journal of biochemistry and molecular biology. vol 37. issue 2. 2004-10-28. PMID:15469702. |
we have previously demonstrated that the redox reactant pyruvate prevents apoptosis in the oxidant model of bovine pulmonary artery endothelial cells (bpaec), and that the anti-apoptotic mechanism of pyruvate is mediated in part via the mitochondrial matrix compartment. |
2004-10-28 |
2023-08-12 |
cattle |
| E Sivridis, A Giatromanolak. New insights into the normal menstrual cycle-regulatory molecules. Histology and histopathology. vol 19. issue 2. 2004-10-25. PMID:15024712. |
at the same time, other proteins promote endometrial cell survival by preventing extracellular matrix degradation and apoptosis. |
2004-10-25 |
2023-08-12 |
Not clear |
| Natsuko Horiguchi, Kei-ichiro Arimoto, Atsushi Mizutani, Yoko Endo-Ichikawa, Hiroshi Nakada, Shigeru Taketan. Galectin-1 induces cell adhesion to the extracellular matrix and apoptosis of non-adherent human colon cancer Colo201 cells. Journal of biochemistry. vol 134. issue 6. 2004-10-21. PMID:14769876. |
galectin-1 induces cell adhesion to the extracellular matrix and apoptosis of non-adherent human colon cancer colo201 cells. |
2004-10-21 |
2023-08-12 |
human |
| Anastasios Tahmatzopoulos, Randall G Rowland, Natasha Kypriano. The role of alpha-blockers in the management of prostate cancer. Expert opinion on pharmacotherapy. vol 5. issue 6. 2004-10-21. PMID:15163273. |
specifically, doxazosin and terazosin can induce apoptosis, inhibit invasion and migration of prostate cancer and endothelial cells, and reduce their adhesion potential to extracellular matrix components, thus enhancing their susceptibility to anoikis. |
2004-10-21 |
2023-08-12 |
Not clear |
| Thomas Pietri, Olivier Eder, Marie Anne Breau, Piotr Topilko, Martine Blanche, Cord Brakebusch, Reinhard Fässler, Jean-Paul Thiery, Sylvie Dufou. Conditional beta1-integrin gene deletion in neural crest cells causes severe developmental alterations of the peripheral nervous system. Development (Cambridge, England). vol 131. issue 16. 2004-10-21. PMID:15253938. |
integrins are transmembrane receptors that are known to interact with the extracellular matrix and to be required for migration, proliferation, differentiation and apoptosis. |
2004-10-21 |
2023-08-12 |
mouse |
| N Philips, D Burchill, D O'Donoghue, T Keller, S Gonzale. Identification of benzene metabolites in dermal fibroblasts as nonphenolic: regulation of cell viability, apoptosis, lipid peroxidation and expression of matrix metalloproteinase 1 and elastin by benzene metabolites. Skin pharmacology and physiology. vol 17. issue 3. 2004-10-19. PMID:15087594. |
identification of benzene metabolites in dermal fibroblasts as nonphenolic: regulation of cell viability, apoptosis, lipid peroxidation and expression of matrix metalloproteinase 1 and elastin by benzene metabolites. |
2004-10-19 |
2023-08-12 |
Not clear |
| Pekka Koistinen, Matti Ahonen, Veli-Matti Kähäri, Jyrki Hein. alphaV integrin promotes in vitro and in vivo survival of cells in metastatic melanoma. International journal of cancer. vol 112. issue 1. 2004-10-19. PMID:15305376. |
in cell culture experiments, the depletion of alphav integrins detached cells from extracellular matrix and induced apoptosis. |
2004-10-19 |
2023-08-12 |
mouse |
| A Mirshafiey, D T Ngoc Dzung, J W Murphy, M R Khorramizadeh, F Saadat, F Mehrabian, P Larsso. Tolerability and anti-inflammatory effects of glucuronoxylomannan in collagen-induced arthritis. Scandinavian journal of immunology. vol 60. issue 3. 2004-10-14. PMID:15320878. |
the wehi-164 cell line was used for assaying tolerability, matrix metalloproteinase type 2 (mmp-2) activity and apoptosis. |
2004-10-14 |
2023-08-12 |
rat |
| Jun Luo, Shang-Tian Yan. Effects of three-dimensional culturing in a fibrous matrix on cell cycle, apoptosis, and MAb production by hybridoma cells. Biotechnology progress. vol 20. issue 1. 2004-10-08. PMID:14763857. |
effects of three-dimensional culturing in a fibrous matrix on cell cycle, apoptosis, and mab production by hybridoma cells. |
2004-10-08 |
2023-08-12 |
Not clear |
| Jun Luo, Shang-Tian Yan. Effects of three-dimensional culturing in a fibrous matrix on cell cycle, apoptosis, and MAb production by hybridoma cells. Biotechnology progress. vol 20. issue 1. 2004-10-08. PMID:14763857. |
the effects of culturing hybridoma cells in a three-dimensional (3-d) poly(ethylene terephthalate) (pet) fibrous matrix on cell cycle, apoptosis, metabolism, and monoclonal antibody (mab) production were evaluated by comparing with two-dimensional (2-d) culturing on microcarrier and multiwell plate surfaces. |
2004-10-08 |
2023-08-12 |
Not clear |
| Jun Luo, Shang-Tian Yan. Effects of three-dimensional culturing in a fibrous matrix on cell cycle, apoptosis, and MAb production by hybridoma cells. Biotechnology progress. vol 20. issue 1. 2004-10-08. PMID:14763857. |
these results suggested that the 3-d fibrous matrix contributed to growth arrest, protected cells to better resist low-serum environments, and reduced apoptosis, all of which contributed to the high viable cell density and volumetric mab productivity in the long-term 3-d culture. |
2004-10-08 |
2023-08-12 |
Not clear |