| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Milan Tjioe, Tim Smits, Willeke A M Blokx, Peter C M van de Kerkhof, Marie-Jeanne P Gerritse. High-dose long wave visible light induces perinuclear vacuolization in vivo but does not result in early photoageing and apoptosis. Experimental dermatology. vol 12. issue 5. 2004-05-27. PMID:14705801. |
the aim of the present study was to investigate the effects of high dose visible light on the skin of healthy volunteers with focus on apoptosis, dna damage, inflammation, melanogenesis and induction of matrix metalloproteinases (mmp). |
2004-05-27 |
2023-08-12 |
human |
| M Benjamin, J R Ralph. Biology of fibrocartilage cells. International review of cytology. vol 233. 2004-05-27. PMID:15037361. |
as in hyaline cartilage, matrix metalloproteinases are important in matrix turnover and fibrocartilage cells are capable of apoptosis. |
2004-05-27 |
2023-08-12 |
Not clear |
| Arusha Oloumi, Timothy McPhee, Shoukat Dedha. Regulation of E-cadherin expression and beta-catenin/Tcf transcriptional activity by the integrin-linked kinase. Biochimica et biophysica acta. vol 1691. issue 1. 2004-05-24. PMID:15053919. |
constitutive activation of ilk in epithelial cells results in oncogenic phenotypes such as disruption of cell extracellular matrix and cell to cell interactions, suppression of suspension-induced apoptosis, and induction of anchorage independent cell growth and cell cycle progression. |
2004-05-24 |
2023-08-12 |
Not clear |
| Ruth A Roberts, Cecile Michel, Beth Coyle, Caroline Freathy, Kelvin Cain, Eric Boitie. Regulation of apoptosis by peroxisome proliferators. Toxicology letters. vol 149. issue 1-3. 2004-05-24. PMID:15093246. |
cluster a (4h) was associated with 12% apoptosis and consisted of genes mainly of the cytoskeleton and extracellular matrix such as troponin and the proteoglycan sdc4. |
2004-05-24 |
2023-08-12 |
rat |
| Dylan R Edward. TIMP-3 and endocrine therapy of breast cancer: an apoptosis connection emerges. The Journal of pathology. vol 202. issue 4. 2004-05-20. PMID:15095265. |
however, timp-3 has several unique properties that set it apart from other timps, including its ability to bind to extracellular matrix, inhibit related adamalysin metalloproteinases (adams), and induce apoptosis. |
2004-05-20 |
2023-08-12 |
human |
| Paul N Span, Raija L P Lindberg, Peggy Manders, Vivianne C G Tjan-Heijnen, Joop J T M Heuvel, Louk V A M Beex, C G J Swee. Tissue inhibitors of metalloproteinase expression in human breast cancer: TIMP-3 is associated with adjuvant endocrine therapy success. The Journal of pathology. vol 202. issue 4. 2004-05-20. PMID:15095266. |
tissue inhibitors of matrix metalloproteinase (timps) may be involved in tumour growth, apoptosis, angiogenesis, invasion, and the development of metastases. |
2004-05-20 |
2023-08-12 |
human |
| Susan M Hall, Alison A Hislop, Zhongshi Wu, Sheila G Hawort. Remodelling of the pulmonary arteries during recovery from pulmonary hypertension induced by neonatal hypoxia. The Journal of pathology. vol 203. issue 1. 2004-05-20. PMID:15095481. |
using light and electron microscopy, the pulmonary artery wall thickness, the relative contribution of smooth muscle and matrix, smooth muscle cell replication, and apoptosis were assessed after hypoxic exposure and during recovery from hypoxic exposure. |
2004-05-20 |
2023-08-12 |
Not clear |
| Susan M Hall, Alison A Hislop, Zhongshi Wu, Sheila G Hawort. Remodelling of the pulmonary arteries during recovery from pulmonary hypertension induced by neonatal hypoxia. The Journal of pathology. vol 203. issue 1. 2004-05-20. PMID:15095481. |
in elastic arteries, after 6 days' recovery in room air, a reduction in wall thickness to normal was associated with a similar reduction in proportional area of smooth muscle cells and matrix (p < 0.05), increased apoptosis (p < 0.05), and an abnormally low replication rate (p < 0.05). |
2004-05-20 |
2023-08-12 |
Not clear |
| Richard A Lockshin, Zahra Zaker. Caspase-independent cell death? Oncogene. vol 23. issue 16. 2004-05-06. PMID:15077140. |
cells frequently display activation of other proteases, including granzymes, lysosomal cathepsins, matrix metalloproteinases, and proteasomal proteases, and others display morphologies that are not fully consistent with classical apoptosis. |
2004-05-06 |
2023-08-12 |
Not clear |
| M Tjioe, M J P Gerritsen, A A Den Broeder, C A E M Van Hooijdonk, E J A Kroot, P L C M Van Riel, P Barrera, P C M Van De Kerkho. Adalimumab, a fully human anti-TNF-alpha monoclonal antibody, treatment does not influence experimental UV response in the skin of rheumatoid arthritis patients. Experimental dermatology. vol 12. issue 4. 2004-05-03. PMID:12930303. |
the aim of the present study was to investigate the effect of anti-tnf-alpha treatment on uv-induced dna damage, apoptosis, and induction of matrix metallo proteinases. |
2004-05-03 |
2023-08-12 |
human |
| Wook Kim, Seunghyi Kook, Dae Joong Kim, Carmen Teodorof, Woo Keun Son. The 31-kDa caspase-generated cleavage product of p130cas functions as a transcriptional repressor of E2A in apoptotic cells. The Journal of biological chemistry. vol 279. issue 9. 2004-05-03. PMID:14660614. |
in response to integrin receptor binding to the extracellular matrix, the multidomain docking protein p130(cas) (crk-associated substrate) activates various signaling cascades modulating such cellular processes as proliferation, migration, and apoptosis. |
2004-05-03 |
2023-08-12 |
Not clear |
| M A Karsdal, T A Andersen, L Bonewald, C Christianse. Matrix metalloproteinases (MMPs) safeguard osteoblasts from apoptosis during transdifferentiation into osteocytes: MT1-MMP maintains osteocyte viability. DNA and cell biology. vol 23. issue 3. 2004-05-03. PMID:15068585. |
matrix metalloproteinases (mmps) safeguard osteoblasts from apoptosis during transdifferentiation into osteocytes: mt1-mmp maintains osteocyte viability. |
2004-05-03 |
2023-08-12 |
mouse |
| M A Karsdal, T A Andersen, L Bonewald, C Christianse. Matrix metalloproteinases (MMPs) safeguard osteoblasts from apoptosis during transdifferentiation into osteocytes: MT1-MMP maintains osteocyte viability. DNA and cell biology. vol 23. issue 3. 2004-05-03. PMID:15068585. |
osteoblasts undergo apoptosis or differentiate into either osteocytes or bone-lining cells after termination of bone matrix synthesis. |
2004-05-03 |
2023-08-12 |
mouse |
| M A Karsdal, T A Andersen, L Bonewald, C Christianse. Matrix metalloproteinases (MMPs) safeguard osteoblasts from apoptosis during transdifferentiation into osteocytes: MT1-MMP maintains osteocyte viability. DNA and cell biology. vol 23. issue 3. 2004-05-03. PMID:15068585. |
in this study, we investigated the role of matrix metalloproteinases (mmps) in differentiation of osteoblasts, bone formation, transdifferentiation into osteocytes, and osteocyte apoptosis. |
2004-05-03 |
2023-08-12 |
mouse |
| Mohamed H Lareef, Quivo Tahin, Joon Song, Irma H Russo, Dana Mihaila, Carolyn M Slater, Binaifer Balsara, Joseph R Testa, Dominique Broccoli, Jennifer V Grobelny, Gil Mor, Andrew Cuthbert, Jose Russ. Chromosome 17p13.2 transfer reverts transformation phenotypes and Fas-mediated apoptosis in breast epithelial cells. Molecular carcinogenesis. vol 39. issue 4. 2004-04-30. PMID:15057875. |
transformation of the human breast epithelial cells (hbec) mcf-10f with the carcinogen benz(a)pyrene (bp) into bp1-e cells resulted in the loss of the chromosome 17 p13.2 locus (d17s796 marker) and formation of colonies in agar-methocel (colony efficiency (ce)), loss of ductulogenic capacity in collagen matrix, and resistance to anti-fas monoclonal antibody (mab)-induced apoptosis. |
2004-04-30 |
2023-08-12 |
mouse |
| Dietlind Zohlnhöfer, Thomas G Nührenberg, Franz-Josef Neumann, Thomas Richter, Andreas E May, Roland Schmidt, Katja Denker, Matthias A Clauss, Albert Schömig, Patrick A Baeuerl. Rapamycin effects transcriptional programs in smooth muscle cells controlling proliferative and inflammatory properties. Molecular pharmacology. vol 65. issue 4. 2004-04-21. PMID:15044617. |
in addition, we found changes in the expression of genes associated with replication, apoptosis, and extracellular matrix formation. |
2004-04-21 |
2023-08-12 |
human |
| Dietlind Zohlnhöfer, Thomas G Nührenberg, Franz-Josef Neumann, Thomas Richter, Andreas E May, Roland Schmidt, Katja Denker, Matthias A Clauss, Albert Schömig, Patrick A Baeuerl. Rapamycin effects transcriptional programs in smooth muscle cells controlling proliferative and inflammatory properties. Molecular pharmacology. vol 65. issue 4. 2004-04-21. PMID:15044617. |
the effects reported here of rapamycin on the down-regulation of genes involved in cell cycle progression, apoptosis, proliferation, and extracellular matrix formation in casmcs provide an explanation of how rapamycin reduces casmc proliferation. |
2004-04-21 |
2023-08-12 |
human |
| R D Catalano, A Yanaihara, A L Evans, D Rocha, A Prentice, S Saidi, C G Print, D S Charnock-Jones, A M Sharkey, S K Smit. The effect of RU486 on the gene expression profile in an endometrial explant model. Molecular human reproduction. vol 9. issue 8. 2004-04-16. PMID:12837923. |
endometrial biopsies from five normal fertile women at mid-secretory phase were cultured in the presence of estradiol and progesterone with or without ru486 for 12 h. cdna arrays were produced containing approximately 1000 sequence-verified clones which included genes known to be important in angiogenesis, apoptosis, cell signalling, extracellular matrix remodelling and cell cycle regulation. |
2004-04-16 |
2023-08-12 |
Not clear |
| Begoña Santiago, María Galindo, Guillermo Palao, José L Pablo. Intracellular regulation of Fas-induced apoptosis in human fibroblasts by extracellular factors and cycloheximide. Journal of immunology (Baltimore, Md. : 1950). vol 172. issue 1. 2004-04-02. PMID:14688367. |
exogenous growth factors, cytokines, and adherence to the extracellular matrix shifted the balance of flip-caspase-8 proteins and modified the susceptibility of df to fas- or fas-chx-induced apoptosis. |
2004-04-02 |
2023-08-12 |
human |
| Jiale He, Linda G Bau. Presentation of galectin-1 by extracellular matrix triggers T cell death. The Journal of biological chemistry. vol 279. issue 6. 2004-04-01. PMID:14617626. |
t cell apoptosis can be initiated by a variety of triggers, including galectin-1, a soluble, secreted lectin that binds to oligosaccharide ligands on cell surface glycoproteins, or to oligosaccharide ligands on extracellular matrix glycoproteins in tissue stroma. |
2004-04-01 |
2023-08-12 |
Not clear |