| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jan Pinkas, Stuart S Martin, Philip Lede. Bcl-2-mediated cell survival promotes metastasis of EpH4 betaMEKDD mammary epithelial cells. Molecular cancer research : MCR. vol 2. issue 10. 2005-03-04. PMID:15498929. |
detachment of epithelial cells from the extracellular matrix causes disruption of the actin cytoskeleton and induces apoptosis. |
2005-03-04 |
2023-08-12 |
mouse |
| Chikako Odaka, Masatoshi Tanioka, Takeshi Ito. Matrix metalloproteinase-9 in macrophages induces thymic neovascularization following thymocyte apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 174. issue 2. 2005-03-03. PMID:15634906. |
matrix metalloproteinase-9 in macrophages induces thymic neovascularization following thymocyte apoptosis. |
2005-03-03 |
2023-08-12 |
mouse |
| Chikako Odaka, Masatoshi Tanioka, Takeshi Ito. Matrix metalloproteinase-9 in macrophages induces thymic neovascularization following thymocyte apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 174. issue 2. 2005-03-03. PMID:15634906. |
these studies demonstrate a potential role of macrophage mmp-9 in the remodeling of thymic extracellular matrix following thymocyte apoptosis. |
2005-03-03 |
2023-08-12 |
mouse |
| Rujun Gong, Abdalla Rifai, Evelyn M Tolbert, Purba Biswas, Jason N Centracchio, Lance D Dworki. Hepatocyte growth factor ameliorates renal interstitial inflammation in rat remnant kidney by modulating tubular expression of macrophage chemoattractant protein-1 and RANTES. Journal of the American Society of Nephrology : JASN. vol 15. issue 11. 2005-03-02. PMID:15504940. |
suggested mechanisms to explain this action include prevention of tubular cell apoptosis, blocking epithelial-to-mesenchymal transition, and promotion of extracellular matrix degradation. |
2005-03-02 |
2023-08-12 |
rat |
| Pauli A Puolakkainen, Rolf A Brekken, Sabeeha Muneer, E Helene Sag. Enhanced growth of pancreatic tumors in SPARC-null mice is associated with decreased deposition of extracellular matrix and reduced tumor cell apoptosis. Molecular cancer research : MCR. vol 2. issue 4. 2005-02-18. PMID:15140943. |
enhanced growth of pancreatic tumors in sparc-null mice is associated with decreased deposition of extracellular matrix and reduced tumor cell apoptosis. |
2005-02-18 |
2023-08-12 |
mouse |
| Harald Bradl, Wolfgang Schuh, Hans-Martin Jäc. CD44 is dispensable for B lymphopoiesis. Immunology letters. vol 95. issue 1. 2005-02-11. PMID:15325800. |
several studies have implicated a role for the cell surface glycoprotein cd44 in lymphocyte differentiation, adhesion to the matrix, homing, activation and apoptosis. |
2005-02-11 |
2023-08-12 |
mouse |
| Li Guo, Stephen E Moss, Robert A Alexander, Robin R Ali, Frederick W Fitzke, M Francesca Cordeir. Retinal ganglion cell apoptosis in glaucoma is related to intraocular pressure and IOP-induced effects on extracellular matrix. Investigative ophthalmology & visual science. vol 46. issue 1. 2005-02-10. PMID:15623771. |
retinal ganglion cell apoptosis in glaucoma is related to intraocular pressure and iop-induced effects on extracellular matrix. |
2005-02-10 |
2023-08-12 |
rat |
| Li Guo, Stephen E Moss, Robert A Alexander, Robin R Ali, Frederick W Fitzke, M Francesca Cordeir. Retinal ganglion cell apoptosis in glaucoma is related to intraocular pressure and IOP-induced effects on extracellular matrix. Investigative ophthalmology & visual science. vol 46. issue 1. 2005-02-10. PMID:15623771. |
to investigate the effect of iop on retinal ganglion cell (rgc) apoptosis and correlate the effects with iop-induced changes in extracellular matrix (ecm) in the retina and optic nerve head (onh) in glaucomatous rat eyes. |
2005-02-10 |
2023-08-12 |
rat |
| Moisés Selman, Annie Pard. Idiopathic pulmonary fibrosis: misunderstandings between epithelial cells and fibroblasts? Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG. vol 21. issue 3. 2005-02-07. PMID:15554072. |
active fibroblasts/myofibroblasts from these foci may in turn disturb alveolar re-epithelialization, by provoking basement membrane disruption and epithelial cell apoptosis finally resulting in exaggerated extracellular matrix accumulation. |
2005-02-07 |
2023-08-12 |
Not clear |
| Sen Rong Yan, Kusum Sapru, Andrew C Issekut. The CD11/CD18 (beta2) integrins modulate neutrophil caspase activation and survival following TNF-alpha or endotoxin induced transendothelial migration. Immunology and cell biology. vol 82. issue 4. 2005-02-04. PMID:15283855. |
thus, engagement of ligands on extracellular matrix and endothelium by the beta2 integrins mac-1 and lfa-1 plays a role in delaying apoptosis in pmn recruited in response to lps and tnf-alpha. |
2005-02-04 |
2023-08-12 |
Not clear |
| Meinhard Schiller, Delphine Javelaud, Alain Mauvie. TGF-beta-induced SMAD signaling and gene regulation: consequences for extracellular matrix remodeling and wound healing. Journal of dermatological science. vol 35. issue 2. 2005-02-02. PMID:15265520. |
members of the transforming growth factor-beta (tgf-beta) superfamily are pleiotropic cytokines that have the ability to regulate numerous cell functions, including proliferation, differentiation, apoptosis, epithelial-mesenchymal transition, and production of extracellular matrix, allowing them to play an important role during embryonic development and for maintenance of tissue homeostasis. |
2005-02-02 |
2023-08-12 |
Not clear |
| M J Martin, J C Buckland-Wrigh. Sensitivity analysis of a novel mathematical model identifies factors determining bone resorption rates. Bone. vol 35. issue 4. 2005-02-02. PMID:15454099. |
growth factors released from the matrix during phase i were assumed to cause two negative feedback effects: (1) the inhibitory effect of transforming growth factor-beta1 (tgfbeta1)-induced production of opg by marrow osteoblast stromal cells, reducing effective rankl; (2) the apoptosis of osteoclast nuclei assumed to occur at high concentrations of tgfbeta. |
2005-02-02 |
2023-08-12 |
Not clear |
| Jang-Soo Chu. Expression, activity, and regulation of MAP kinases in cultured chondrocytes. Methods in molecular medicine. vol 100. 2005-01-31. PMID:15280602. |
the map kinase subtypes are constitutively expressed in articular chondrocytes and they regulate chondrocyte function, including differentiation, apoptosis, inflammatory responses, and activation of matrix metalloproteinases. |
2005-01-31 |
2023-08-12 |
Not clear |
| Tetsuya Watanabe, Kinya Ots. [Signal transduction in heart failure]. Nihon rinsho. Japanese journal of clinical medicine. vol 62. issue 12. 2005-01-28. PMID:15597806. |
meanwhile, not only myocyte apoptosis but also myocardial interstitial changes such as extracellular matrix deposition, activation of fibroblasts, and narrowing of vessel lumens play important roles for the progression of heart failure. |
2005-01-28 |
2023-08-12 |
Not clear |
| Patricia Saravia-Otten, Teresa Frisan, Monica Thelestam, José María Gutiérre. Membrane independent activation of fibroblast proMMP-2 by snake venom: novel roles for venom proteinases. Toxicon : official journal of the International Society on Toxinology. vol 44. issue 7. 2005-01-27. PMID:15500851. |
activation of prommp-2 by snake venom proteinases, independently of the mt1-mmp/timp-2 pathway, extracellular matrix degradation or apoptosis, represents a novel mechanism in human fibroblasts. |
2005-01-27 |
2023-08-12 |
mouse |
| W Kimryn Rathmell, Michele M Hickey, Natalie A Bezman, Christie A Chmielecki, Natalie C Carraway, M Celeste Simo. In vitro and in vivo models analyzing von Hippel-Lindau disease-specific mutations. Cancer research. vol 64. issue 23. 2005-01-27. PMID:15574766. |
the vhl protein (pvhl) has been implicated in many cellular activities including the hypoxia response, cell cycle arrest, apoptosis, and extracellular matrix remodeling. |
2005-01-27 |
2023-08-12 |
mouse |
| Tracey Hanks, Brent Lee Atkinso. Comparison of cell viability on anorganic bone matrix with or without P-15 cell binding peptide. Biomaterials. vol 25. issue 19. 2005-01-25. PMID:15120530. |
two routinely utilized bone graft materials, anorganic bone matrix (abm) and abm carrying the cell binding peptide p-15 were compared for cell viability and apoptosis. |
2005-01-25 |
2023-08-12 |
human |
| Yan Zhang, Hai Lu, Paul Dazin, Yvonne Kapil. Squamous cell carcinoma cell aggregates escape suspension-induced, p53-mediated anoikis: fibronectin and integrin alphav mediate survival signals through focal adhesion kinase. The Journal of biological chemistry. vol 279. issue 46. 2005-01-21. PMID:15331608. |
resistance to anoikis, or apoptosis triggered by detachment from the extracellular matrix (ecm), lengthens the survival of malignant cells, facilitating reattachment and colonization of secondary sites. |
2005-01-21 |
2023-08-12 |
human |
| Rama Garimella, Xiahong Bi, Nancy Camacho, Joseph B Sipe, H Clarke Anderso. Primary culture of rat growth plate chondrocytes: an in vitro model of growth plate histotype, matrix vesicle biogenesis and mineralization. Bone. vol 34. issue 6. 2005-01-14. PMID:15193542. |
chondrocytes of growth plate undergo proliferation, maturation, hypertrophy, matrix vesicle (mv) biogenesis and programmed cell death (pcd, apoptosis). |
2005-01-14 |
2023-08-12 |
rat |
| A J Valentijn, N Zouq, A P Gilmor. Anoikis. Biochemical Society transactions. vol 32. issue Pt3. 2005-01-12. PMID:15157151. |
adhesion on the extracellular matrix is important to determine whether a cell is in the correct location and to delete displaced cells by apoptosis. |
2005-01-12 |
2023-08-12 |
Not clear |