| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eric Meyer, Jean-Yves Vollmer, Raymonde Bovey, Ivan Stamenkovi. Matrix metalloproteinases 9 and 10 inhibit protein kinase C-potentiated, p53-mediated apoptosis. Cancer research. vol 65. issue 10. 2005-07-07. PMID:15899818. |
matrix metalloproteinases 9 and 10 inhibit protein kinase c-potentiated, p53-mediated apoptosis. |
2005-07-07 |
2023-08-12 |
human |
| Krishnamurthy P Gudehithlu, Naila Ahmed, Henry Wu, Natalia O Litbarg, Sandra L Garber, Jose A L Arruda, George Dunea, Ashok K Sing. Antagonism of vascular endothelial growth factor results in microvessel attrition and disorganization of wound tissue. The Journal of laboratory and clinical medicine. vol 145. issue 4. 2005-07-07. PMID:15962838. |
after injection of the vegf receptor antagonist in the fully formed granuloma, the preexisting blood vessels in the middle layer regressed and underwent apoptosis, accompanied by expansion of the extracellular matrix (predominately collagen i) into areas normally devoid of matrix. |
2005-07-07 |
2023-08-12 |
rat |
| John J Bissler, Bradley P Dixo. A mechanistic approach to inherited polycystic kidney disease. Pediatric nephrology (Berlin, Germany). vol 20. issue 5. 2005-07-06. PMID:15719257. |
the dysregulation of renal tubular epithelial cell biology, including cell polarity, cell signaling, proliferation and apoptosis, basement membrane and matrix abnormalities, and fluid transport, has been postulated to contribute to cystogenesis. |
2005-07-06 |
2023-08-12 |
Not clear |
| Haibo Zhao, F Patrick Ross, Steven L Teitelbau. Unoccupied alpha(v)beta3 integrin regulates osteoclast apoptosis by transmitting a positive death signal. Molecular endocrinology (Baltimore, Md.). vol 19. issue 3. 2005-06-28. PMID:15591537. |
consistent with the posture that alpha(v)beta3 occupancy promotes survival, preosteoclasts plated on native collagen, a matrix not recognized by the integrin, undergo apoptosis 4-fold faster than those on the alpha(v)beta3 ligand, vitronectin. |
2005-06-28 |
2023-08-12 |
Not clear |
| Jonathan C Choy, Vivian H Y Hung, Arwen L Hunter, Paul K Cheung, Bruce Motyka, Ing Swie Goping, Tracy Sawchuk, R Chris Bleackley, Thomas J Podor, Bruce M McManus, David J Granvill. Granzyme B induces smooth muscle cell apoptosis in the absence of perforin: involvement of extracellular matrix degradation. Arteriosclerosis, thrombosis, and vascular biology. vol 24. issue 12. 2005-06-21. PMID:15472125. |
granzyme b induces smooth muscle cell apoptosis in the absence of perforin: involvement of extracellular matrix degradation. |
2005-06-21 |
2023-08-12 |
Not clear |
| Amy W Rachfal, David R Brigstoc. Structural and functional properties of CCN proteins. Vitamins and hormones. vol 70. 2005-06-21. PMID:15727802. |
the ccn family currently comprises six members (ccn1-6) that regulate diverse cell functions, including mitogenesis, adhesion, apoptosis, extracellular matrix (ecm) production, growth arrest, and migration. |
2005-06-21 |
2023-08-12 |
Not clear |
| Jolanta M Wodzinsk. Transglutaminases as targets for pharmacological inhibition. Mini reviews in medicinal chemistry. vol 5. issue 3. 2005-06-21. PMID:15777262. |
transglutaminases (tgases), a family of enzymes that catalyze the formation of epsilon-(gamma-glutamyl)lysine isopeptide linkage, play an important physiological role in hemostasis, wound healing, assembly and remodeling of the extracellular matrix, cell signaling and apoptosis. |
2005-06-21 |
2023-08-12 |
human |
| G Astrid Limb, Karl Matter, Gillian Murphy, Alison D Cambrey, Paul N Bishop, Glenn E Morris, Peng T Kha. Matrix metalloproteinase-1 associates with intracellular organelles and confers resistance to lamin A/C degradation during apoptosis. The American journal of pathology. vol 166. issue 5. 2005-06-21. PMID:15855654. |
matrix metalloproteinase-1 associates with intracellular organelles and confers resistance to lamin a/c degradation during apoptosis. |
2005-06-21 |
2023-08-12 |
Not clear |
| Gwénola Boulday, Juliette Fitau, Stéphanie Coupel, Jean-Paul Soulillou, Béatrice Charrea. Exogenous tissue inhibitor of metalloproteinase-1 promotes endothelial cell survival through activation of the phosphatidylinositol 3-kinase/Akt pathway. Annals of the New York Academy of Sciences. vol 1030. 2005-06-16. PMID:15659777. |
in addition to inhibiting matrix metalloproteinase activity, it has been suggested by recent studies that the tissue inhibitor of metalloproteinase (timp)-1 may inhibit apoptosis in various cell types. |
2005-06-16 |
2023-08-12 |
human |
| Wei Li, Xi-Ming Yua. Increased expression and translocation of lysosomal cathepsins contribute to macrophage apoptosis in atherogenesis. Annals of the New York Academy of Sciences. vol 1030. 2005-06-16. PMID:15659826. |
the increased macrophage apoptosis and nuclear and matrix degradation by lysosomal enzymes in atheroma may play important roles in plaque development and rupture. |
2005-06-16 |
2023-08-12 |
mouse |
| Nobuko Sakai, Ken Iseki, Shigeo Suzuki, Tetsuji Mori, Seita Hagino, Yuxiang Zhang, Sachihiko Yokoya, Yukihiko Kawasaki, Junzo Suzuki, Masato Isome, Ikuo Wada, Yoshimi Homma, Hitoshi Suzuk. Uninephrectomy induces progressive glomerulosclerosis and apoptosis in anti-Thy1 glomerulonephritis. Pathology international. vol 55. issue 1. 2005-06-14. PMID:15660699. |
it is suggested that apoptosis and extracellular matrix accumulation play an important role in the development of glomerulosclerosis. |
2005-06-14 |
2023-08-12 |
human |
| Yasunori Fujimoto, Shuichi Izumoto, Tsuyoshi Suzuki, Manabu Kinoshita, Naoki Kagawa, Kouichi Wada, Naoya Hashimoto, Motohiko Maruno, Yuji Nakatsuji, Toshiki Yoshimin. Ganglioside GM3 inhibits proliferation and invasion of glioma. Journal of neuro-oncology. vol 71. issue 2. 2005-06-14. PMID:15690123. |
gm3, the simplest ganglioside, modulates cell adhesion, proliferation and differentiation in the central nervous system and exogenously added gm3 regulates cell-cell and cell-extracellular matrix adhesion and induces apoptosis. |
2005-06-14 |
2023-08-12 |
rat |
| Laimute Taraseviciene-Stewart, Robertas Scerbavicius, Kang-Hyeon Choe, Melissa Moore, Andrew Sullivan, Mark R Nicolls, Andrew P Fontenot, Rubin M Tuder, Norbert F Voelke. An animal model of autoimmune emphysema. American journal of respiratory and critical care medicine. vol 171. issue 7. 2005-06-08. PMID:15563631. |
immunization with ecs also leads to alveolar septal cell apoptosis and activation of matrix metalloproteases mmp-9 and mmp-2. |
2005-06-08 |
2023-08-12 |
mouse |
| F Mannello, F Luchetti, E Falcieri, S Pap. Multiple roles of matrix metalloproteinases during apoptosis. Apoptosis : an international journal on programmed cell death. vol 10. issue 1. 2005-06-06. PMID:15711919. |
multiple roles of matrix metalloproteinases during apoptosis. |
2005-06-06 |
2023-08-12 |
Not clear |
| Jarrod Bailey, Alison J Tyson-Capper, Kate Gilmore, Stephen C Robson, G Nicholas Europe-Finne. Identification of human myometrial target genes of the cAMP pathway: the role of cAMP-response element binding (CREB) and modulator (CREMalpha and CREMtau2alpha) proteins. Journal of molecular endocrinology. vol 34. issue 1. 2005-06-02. PMID:15691874. |
genes involved in regulation of cell death and apoptosis, growth and maintenance, signal transduction, physiological and developmental processes, protein kinase cascades, extracellular matrix, cytoskeleton, cell-cycle regulation, transport, and a variety of enzymes, intracellular components and nucleic acid-binding proteins have been described, many of which are involved in the modulation of myometrial activity during pregnancy and parturition. |
2005-06-02 |
2023-08-12 |
human |
| Paul M Coussens, Chas B Pudrith, Kerstin Skovgaard, Xiaoning Ren, Steven P Suchyta, Judith R Stabel, Peter M H Heegaar. Johne's disease in cattle is associated with enhanced expression of genes encoding IL-5, GATA-3, tissue inhibitors of matrix metalloproteinases 1 and 2, and factors promoting apoptosis in peripheral blood mononuclear cells. Veterinary immunology and immunopathology. vol 105. issue 3-4. 2005-06-01. PMID:15808302. |
johne's disease in cattle is associated with enhanced expression of genes encoding il-5, gata-3, tissue inhibitors of matrix metalloproteinases 1 and 2, and factors promoting apoptosis in peripheral blood mononuclear cells. |
2005-06-01 |
2023-08-12 |
cattle |
| Paul M Coussens, Chas B Pudrith, Kerstin Skovgaard, Xiaoning Ren, Steven P Suchyta, Judith R Stabel, Peter M H Heegaar. Johne's disease in cattle is associated with enhanced expression of genes encoding IL-5, GATA-3, tissue inhibitors of matrix metalloproteinases 1 and 2, and factors promoting apoptosis in peripheral blood mononuclear cells. Veterinary immunology and immunopathology. vol 105. issue 3-4. 2005-06-01. PMID:15808302. |
our results indicate that t cells within pbmcs from m. paratuberculosis-infected cows have adopted a predominant th 2-like phenotype (enhanced expression of il-5, gata 3, and possibly il-4 mrna), that cells within infected cow pbmcs may exhibit tissue remodeling deficiencies through higher expression of tissue inhibitor of matrix metalloproteinase (timp) 1 and timp2 rna and lower expression of matrix metalloproteinase (mmp) 14 rna than similar cells from healthy controls, and that cells within the pbmc population of m. paratuberculosis-infected cows are likely poised for rapid apoptosis (upregulation of cide-a, bad, tnfri, and fas). |
2005-06-01 |
2023-08-12 |
cattle |
| Shulin Xiang, Weihong Pan, Abba J Kasti. Strategies to create a regenerating environment for the injured spinal cord. Current pharmaceutical design. vol 11. issue 10. 2005-05-25. PMID:15853683. |
the strategies are classified into the following categories: penetration of the blood-brain barrier; modulation of caspase activity to reduce apoptosis; stem cells and tissue implantation; administration of neurotrophic factors, including viral vector-mediated delivery; and modulation of the extracellular matrix. |
2005-05-25 |
2023-08-12 |
Not clear |
| Filiberto Rodriguez, Frank Langer, Katherine B Harrington, Allen Cheng, George T Daughters, John C Criscione, Neil B Ingels, D Craig Mille. Alterations in transmural strains adjacent to ischemic myocardium during acute midcircumflex occlusion. The Journal of thoracic and cardiovascular surgery. vol 129. issue 4. 2005-05-19. PMID:15821645. |
normal cardiac microstructure and strains are optimized; deviations could result in apoptosis and deleterious matrix remodeling, which degenerates into global cardiomyopathy. |
2005-05-19 |
2023-08-12 |
Not clear |
| Oscar Gonzalez-Moreno, Alfonso Calvo, Bharat H Joshi, Ibane Abasolo, Pamela Leland, Zhou Wang, Luis Montuenga, Raj K Puri, Jeffrey E Gree. Gene expression profiling identifies IL-13 receptor alpha 2 chain as a therapeutic target in prostate tumor cells overexpressing adrenomedullin. International journal of cancer. vol 114. issue 6. 2005-05-16. PMID:15609296. |
examples of such genes include many involved in the formation of the cytoskeleton, cell adhesion and the extracellular matrix, as well as regulators of the cell cycle and apoptosis, cytokines and transcription factors. |
2005-05-16 |
2023-08-12 |
human |