| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kosei Arimura, Naomichi Arima, Kakushi Matsushita, Hideo Ohtsubo, Hiroshi Fujiwara, Toshimasa Kukita, Atsuo Ozaki, Takafumi Hagiwara, Heiichiro Hamada, Kohichiro Yoshino, Chuwa Te. Matrix metalloproteinase inhibitor reduces apoptosis induction of bone marrow cells in MDS-RA. European journal of haematology. vol 73. issue 1. 2004-07-15. PMID:15182333. |
matrix metalloproteinase inhibitor reduces apoptosis induction of bone marrow cells in mds-ra. |
2004-07-15 |
2023-08-12 |
Not clear |
| Xiaoying Zhou, Frank R Murphy, Nitu Gehdu, Junlong Zhang, John P Iredale, R Christopher Benyo. Engagement of alphavbeta3 integrin regulates proliferation and apoptosis of hepatic stellate cells. The Journal of biological chemistry. vol 279. issue 23. 2004-07-08. PMID:15044441. |
stellate cells incubated with active recombinant matrix metalloproteinase-9 showed enhanced apoptosis, while cells treated with a synthetic inhibitor of this protease showed increased survival. |
2004-07-08 |
2023-08-12 |
human |
| Xiaoying Zhou, Frank R Murphy, Nitu Gehdu, Junlong Zhang, John P Iredale, R Christopher Benyo. Engagement of alphavbeta3 integrin regulates proliferation and apoptosis of hepatic stellate cells. The Journal of biological chemistry. vol 279. issue 23. 2004-07-08. PMID:15044441. |
degradation of alpha(v)beta(3) ligands surrounding activated stellate cells during resolution of liver fibrosis might decrease alpha(v)beta(3) integrin ligation, suppressing stellate cell proliferation and inducing a fibrolytic, matrix metalloproteinase-secreting phenotype that may prime stellate cells for apoptosis. |
2004-07-08 |
2023-08-12 |
human |
| Philip B Sugerman, Sara B Faber, Lucy M Willis, Aleksandra Petrovic, George F Murphy, Jacques Pappo, David Silberstein, Marcel R M van den Brin. Kinetics of gene expression in murine cutaneous graft-versus-host disease. The American journal of pathology. vol 164. issue 6. 2004-07-08. PMID:15161652. |
the sequential infiltration and activation of effector cells correlated with the histopathological development of cutaneous gvhd and was accompanied by up-regulated expression of many chemokines and their receptors (cxcl-1, -2, -9, and -10; ccl-2, -5, -6, -7, -8, -9, -11, and -19; ccr-1 and ccr-5), adhesion molecules (icam-1, cd18, ly69, psgl-1, vcam-1), molecules involved in antigen processing and presentation (tap1 and tap2, mhc class i and ii, cd80), regulators of apoptosis (granzyme b, caspase 7, bak1, bax, and bclii), interferon-inducible genes (stat1, irf-1, iigp, gtpi, igtp, ifi202a), stimulators of fibroblast proliferation and matrix synthesis (interleukin-1beta, transforming growth factor-beta1), and markers of keratinocyte proliferation (keratins 5 and 6), and differentiation (small proline-rich proteins 2e and 1b). |
2004-07-08 |
2023-08-12 |
mouse |
| A P Sutter, M Zeitz, H Scherüb. Recent results in understanding molecular pathways in the medical treatment of esophageal and gastric cancer. Onkologie. vol 27. issue 1. 2004-07-07. PMID:15007244. |
therapeutic strategies discussed include agents targeting the epidermal growth factor receptor (egfr) family, the mitogen-activated protein kinase (mapk) pathway, regulators of apoptosis (nf-kappab, bcl-2, and the peripheral benzodiazepine receptor), cyclooxygenase-2, the vascular-endothelial growth factor receptor and matrix metalloproteinases. |
2004-07-07 |
2023-08-12 |
Not clear |
| Rongfa Bu, Christopher W Borysenko, Yanan Li, Lihuan Cao, Afsie Sabokbar, Harry C Blai. Expression and function of TNF-family proteins and receptors in human osteoblasts. Bone. vol 33. issue 5. 2004-07-06. PMID:14623051. |
mg63 cells were resistant to apoptosis by exogenous tnfalpha except when grown in media promoting osteoblast-like growth or matrix nodules. |
2004-07-06 |
2023-08-12 |
human |
| Jong Bin Kim, Robert Stein, Mike J O'Har. Three-dimensional in vitro tissue culture models of breast cancer-- a review. Breast cancer research and treatment. vol 85. issue 3. 2004-07-01. PMID:15111767. |
three dimensional in vitro models allow the study of cell-cell and cell-extracellular matrix interactions, in addition to the influence of the microenvironment on cellular differentiation, proliferation, apoptosis and gene expression. |
2004-07-01 |
2023-08-12 |
Not clear |
| Raïd Kassis, Florence Larrous, Jérôme Estaquier, Hervé Bourh. Lyssavirus matrix protein induces apoptosis by a TRAIL-dependent mechanism involving caspase-8 activation. Journal of virology. vol 78. issue 12. 2004-06-29. PMID:15163747. |
lyssavirus matrix protein induces apoptosis by a trail-dependent mechanism involving caspase-8 activation. |
2004-06-29 |
2023-08-12 |
Not clear |
| Raïd Kassis, Florence Larrous, Jérôme Estaquier, Hervé Bourh. Lyssavirus matrix protein induces apoptosis by a TRAIL-dependent mechanism involving caspase-8 activation. Journal of virology. vol 78. issue 12. 2004-06-29. PMID:15163747. |
transfection of cells with the matrix protein induced apoptosis using pathways similar to those described in the context of viral infection. |
2004-06-29 |
2023-08-12 |
Not clear |
| Raïd Kassis, Florence Larrous, Jérôme Estaquier, Hervé Bourh. Lyssavirus matrix protein induces apoptosis by a TRAIL-dependent mechanism involving caspase-8 activation. Journal of virology. vol 78. issue 12. 2004-06-29. PMID:15163747. |
furthermore, our data suggest that the matrix protein of lyssaviruses plays a major role in the early induction of trail-mediated apoptosis by the release of a soluble, active form of trail. |
2004-06-29 |
2023-08-12 |
Not clear |
| Vito Turk, Janko Kos, Boris Tur. Cysteine cathepsins (proteases)--on the main stage of cancer? Cancer cell. vol 5. issue 5. 2004-06-28. PMID:15144947. |
cysteine cathepsins are involved in degradation of extracellular matrix, facilitating growth, invasion, and metastasis of tumor cells, in tumor angiogenesis, in apoptosis, and in events of inflammatory and immune responses. |
2004-06-28 |
2023-08-12 |
mouse |
| Neeraj Vij, Luke Roberts, Sarah Joyce, Shukti Chakravart. Lumican suppresses cell proliferation and aids Fas-Fas ligand mediated apoptosis: implications in the cornea. Experimental eye research. vol 78. issue 5. 2004-06-25. PMID:15051477. |
we further investigated the implications of lumican's proliferation and apoptosis regulatory role in the cornea where lumican is a major component of the stromal matrix. |
2004-06-25 |
2023-08-12 |
mouse |
| Rongkun Liu, Tesfahun Desta, Hongbing He, Dana T Grave. Diabetes alters the response to bacteria by enhancing fibroblast apoptosis. Endocrinology. vol 145. issue 6. 2004-06-24. PMID:15033911. |
apoptosis was evident during the peak healing period and coincided with reduced numbers of fibroblasts, diminished collagen i and iii expression, and significantly reduced formation of new connective tissue matrix in diabetic mice. |
2004-06-24 |
2023-08-12 |
mouse |
| M B Santucci, A Ciaramella, M Mattei, T Sumerska, M Frazian. Batimastat reduces Mycobacterium tuberculosis-induced apoptosis in macrophages. International immunopharmacology. vol 3. issue 12. 2004-06-14. PMID:14555290. |
in this study, we report evidences that mycobacterium tuberculosis (mtb)-induced apoptosis in macrophages is reduced by a broad-spectrum hydroxamic acid-based matrix metalloproteinase (mmp) inhibitor, batimastat (bb-94). |
2004-06-14 |
2023-08-12 |
Not clear |
| Alessandro Amore, Paola Cirina, Giovanni Conti, Franco Cerutti, Nayer Bagheri, Steven Noel Emancipator, Rosanna Copp. Amadori-configurated albumin induces nitric oxide-dependent apoptosis of endothelial cells: a possible mechanism of diabetic vasculopathy. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. vol 19. issue 1. 2004-06-08. PMID:14671039. |
since the late stage of diabetic vasculopathy is characterized by reductions in viable cells within an expanded and disorganized matrix, we tested the hypothesis that ga enhances endothelial cell (ec) apoptosis. |
2004-06-08 |
2023-08-12 |
Not clear |
| Piotr Religa, Krzysztof Bojakowski, Zbigniew Gaciong, Johan Thyberg, Ulf Hedi. Arteriosclerosis in rat aortic allografts: dynamics of cell growth, apoptosis and expression of extracellular matrix proteins. Molecular and cellular biochemistry. vol 249. issue 1-2. 2004-06-01. PMID:12956401. |
arteriosclerosis in rat aortic allografts: dynamics of cell growth, apoptosis and expression of extracellular matrix proteins. |
2004-06-01 |
2023-08-12 |
rat |
| Piotr Religa, Krzysztof Bojakowski, Zbigniew Gaciong, Johan Thyberg, Ulf Hedi. Arteriosclerosis in rat aortic allografts: dynamics of cell growth, apoptosis and expression of extracellular matrix proteins. Molecular and cellular biochemistry. vol 249. issue 1-2. 2004-06-01. PMID:12956401. |
the findings demonstrate major cellular and structural changes in the transplanted artery, including activation, proliferation and apoptosis of smcs, and an altered composition of the extracellular matrix. |
2004-06-01 |
2023-08-12 |
rat |
| Piotr Religa, Krzysztof Bojakowski, Zbigniew Gaciong, Johan Thyberg, Ulf Hedi. Arteriosclerosis in rat aortic allografts: dynamics of cell growth, apoptosis and expression of extracellular matrix proteins. Molecular and cellular biochemistry. vol 249. issue 1-2. 2004-06-01. PMID:12956401. |
possibly, the observed changes in smc phenotype, cell cycle and apoptosis during development of transplant arteriosclerosis are related to the expression of extracellular matrix proteins. |
2004-06-01 |
2023-08-12 |
rat |
| Susanne Strand, Petra Vollmer, Lothar van den Abeelen, Daniela Gottfried, Vijay Alla, Hans Heid, Jürgen Kuball, Matthias Theobald, Peter R Galle, Dennis Stran. Cleavage of CD95 by matrix metalloproteinase-7 induces apoptosis resistance in tumour cells. Oncogene. vol 23. issue 20. 2004-06-01. PMID:15077180. |
cleavage of cd95 by matrix metalloproteinase-7 induces apoptosis resistance in tumour cells. |
2004-06-01 |
2023-08-12 |
Not clear |
| Sang-Wook Jee, Shaohui Wang, Yvonne L Kapil. Specific pro-apoptotic fibronectin fragments modulate proteinase expression in periodontal ligament cells. Journal of periodontology. vol 75. issue 4. 2004-06-01. PMID:15152815. |
in periodontal ligament cells in vitro, some fragments elevate the expression of matrix metalloproteinases and serine proteinases, while others induce apoptosis through a mechanism regulated by caspase proteases and specific signaling pathways. |
2004-06-01 |
2023-08-12 |
Not clear |