| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Robert Sidbury, Nicole Neuschler, Erin Neuschler, Ping Sun, Xiao-qi Wang, Richard Miller, Mark Tomai, Elena Puscasiu, Sajiv Gugneja, Amy S Palle. Topically applied imiquimod inhibits vascular tumor growth in vivo. The Journal of investigative dermatology. vol 121. issue 5. 2004-01-22. PMID:14708627. |
imiquimod-treated tumors showed decreased tumor cell proliferation, increased tumor apoptosis, and increased expression of tissue inhibitor of matrix metalloproteinase-1 with decreased activity of matrix metalloproteinase-9. |
2004-01-22 |
2023-08-12 |
mouse |
| Yasuyoshi Miyata, Shigehiko Koga, Shigeru Kanda, Masaharu Nishikido, Tomayoshi Hayashi, Hiroshi Kanetak. Expression of cyclooxygenase-2 in renal cell carcinoma: correlation with tumor cell proliferation, apoptosis, angiogenesis, expression of matrix metalloproteinase-2, and survival. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 9. issue 5. 2004-01-12. PMID:12738729. |
expression of cyclooxygenase-2 in renal cell carcinoma: correlation with tumor cell proliferation, apoptosis, angiogenesis, expression of matrix metalloproteinase-2, and survival. |
2004-01-12 |
2023-08-12 |
Not clear |
| Kenn Holmbeck, Paolo Bianco, Kali Chrysovergis, Susan Yamada, Henning Birkedal-Hanse. MT1-MMP-dependent, apoptotic remodeling of unmineralized cartilage: a critical process in skeletal growth. The Journal of cell biology. vol 163. issue 3. 2004-01-12. PMID:14610065. |
membrane-type 1 matrix metalloproteinase (mt1-mmp)-dependent dissolution of unmineralized cartilages, coupled with apoptosis of nonhypertrophic chondrocytes, mediates remodeling of these cartilages into other tissues. |
2004-01-12 |
2023-08-12 |
Not clear |
| Kenn Holmbeck, Paolo Bianco, Kali Chrysovergis, Susan Yamada, Henning Birkedal-Hanse. MT1-MMP-dependent, apoptotic remodeling of unmineralized cartilage: a critical process in skeletal growth. The Journal of cell biology. vol 163. issue 3. 2004-01-12. PMID:14610065. |
the coordinated apoptosis and matrix metalloproteinase-directed cartilage dissolution is akin to metamorphosis and may thus represent its evolutionary legacy in mammals. |
2004-01-12 |
2023-08-12 |
Not clear |
| Sergey G Kuznetsov, Friederike Anton-Erxleben, Thomas C G Bosc. Epithelial interactions in Hydra: apoptosis in interspecies grafts is induced by detachment from the extracellular matrix. The Journal of experimental biology. vol 205. issue Pt 24. 2004-01-09. PMID:12432005. |
epithelial interactions in hydra: apoptosis in interspecies grafts is induced by detachment from the extracellular matrix. |
2004-01-09 |
2023-08-12 |
Not clear |
| Sergey G Kuznetsov, Friederike Anton-Erxleben, Thomas C G Bosc. Epithelial interactions in Hydra: apoptosis in interspecies grafts is induced by detachment from the extracellular matrix. The Journal of experimental biology. vol 205. issue Pt 24. 2004-01-09. PMID:12432005. |
we therefore suggest that in interspecies grafts, apoptosis is induced by the detachment of epithelial cells from the extracellular matrix (anoikis) and not by a discriminative allorecognition system. |
2004-01-09 |
2023-08-12 |
Not clear |
| R Tracy Ballock, Regis J O'Keef. Physiology and pathophysiology of the growth plate. Birth defects research. Part C, Embryo today : reviews. vol 69. issue 2. 2004-01-06. PMID:12955857. |
through a sequential process of cell proliferation, extracellular matrix synthesis, cellular hypertrophy, matrix mineralization, vascular invasion, and eventually apoptosis, the cartilage model is continually replaced by bone as length increases. |
2004-01-06 |
2023-08-12 |
human |
| Ju Hong Jeon, Chai Wan Kim, Dong Myung Shin, Kyu il Kim, Sung Yup Cho, Joon Cheol Kwon, Kyung Ho Choi, Heun Soo Kang, In Gyu Ki. Differential incorporation of biotinylated polyamines by transglutaminase 2. FEBS letters. vol 534. issue 1-3. 2004-01-05. PMID:12527383. |
polyamine incorporation or cross-linking of proteins, post-translational modifications mediated by transglutaminase 2 (tgase 2), have been implicated in a variety of physiological functions including cell adhesion, extracellular matrix formation and apoptosis. |
2004-01-05 |
2023-08-12 |
Not clear |
| Antonio Pacifico, Philip D Henr. Structural pathways and prevention of heart failure and sudden death. Journal of cardiovascular electrophysiology. vol 14. issue 7. 2004-01-05. PMID:12930259. |
the microscopic myocardial anatomy of scd is incompletely defined but may include prevalent changes of advanced myocardial disease, including cardiomyocyte hypertrophy, cardiomyocyte apoptosis, fibroblast hyperplasia, diffuse and focal matrix protein accumulation, and recruitment of inflammatory cells. |
2004-01-05 |
2023-08-12 |
Not clear |
| C S Adams, I M Shapir. Mechanisms by which extracellular matrix components induce osteoblast apoptosis. Connective tissue research. vol 44 Suppl 1. 2004-01-05. PMID:12952203. |
mechanisms by which extracellular matrix components induce osteoblast apoptosis. |
2004-01-05 |
2023-08-12 |
Not clear |
| C S Adams, I M Shapir. Mechanisms by which extracellular matrix components induce osteoblast apoptosis. Connective tissue research. vol 44 Suppl 1. 2004-01-05. PMID:12952203. |
the aim of the current investigation is to elucidate the mechanism by which these extracellular matrix components induce bone cell apoptosis. |
2004-01-05 |
2023-08-12 |
Not clear |
| C S Adams, I M Shapir. Mechanisms by which extracellular matrix components induce osteoblast apoptosis. Connective tissue research. vol 44 Suppl 1. 2004-01-05. PMID:12952203. |
the observation that two such pathways exist lends strength to the notion that apoptosis is carefully regulated in bone and that signals from both matrix components act together to trigger the remodeling process. |
2004-01-05 |
2023-08-12 |
Not clear |
| Yoshihiro Taniyama, Kathy K Griendlin. Reactive oxygen species in the vasculature: molecular and cellular mechanisms. Hypertension (Dallas, Tex. : 1979). vol 42. issue 6. 2004-01-05. PMID:14581295. |
these include cell growth, apoptosis, migration, inflammatory gene expression, and matrix regulation. |
2004-01-05 |
2023-08-12 |
Not clear |
| Vinitha Ramachandran, Lora Talley Watts, Shivani Kaushal Maffi, Juanjuan Chen, Steven Schenker, George Henderso. Ethanol-induced oxidative stress precedes mitochondrially mediated apoptotic death of cultured fetal cortical neurons. Journal of neuroscience research. vol 74. issue 4. 2003-12-23. PMID:14598302. |
cells exposed to ethanol (2.5 mg/ml) remained attached to their polylysine matrix during a 24-hr exposure, but they exhibited distinct signs of oxidative stress, decreased viability, and apoptosis. |
2003-12-23 |
2023-08-12 |
rat |
| Debabrata Saha, Konjeti R Sekhar, Carolyn Cao, Jason D Morrow, Hak Choy, Michael L Freema. The antiangiogenic agent SU5416 down-regulates phorbol ester-mediated induction of cyclooxygenase 2 expression by inhibiting nicotinamide adenine dinucleotide phosphate oxidase activity. Cancer research. vol 63. issue 20. 2003-12-22. PMID:14583492. |
increased expression of cyclooxygenase (cox) 2 and the production of pgs appear to provide a survival advantage to transformed cells through the inhibition of apoptosis, increased attachment to extracellular matrix, increased invasiveness and the stimulation of angiogenesis. |
2003-12-22 |
2023-08-12 |
Not clear |
| Antonio Di Sabatino, Rachele Ciccocioppo, Ombretta Luinetti, Laura Ricevuti, Raffaele Morera, Maria Grazia Cifone, Enrico Solcia, Gino Roberto Corazz. Increased enterocyte apoptosis in inflamed areas of Crohn's disease. Diseases of the colon and rectum. vol 46. issue 11. 2003-12-18. PMID:14605569. |
because increased enterocyte apoptosis has been associated with the pathogenesis of several chronic inflammatory diseases, the aim of our study was to investigate epithelial cell death in crohn's disease and the possible role of the fas-fas ligand system, e-cadherin, and matrix metalloproteinase-1 in modulating enterocyte apoptosis in this condition. |
2003-12-18 |
2023-08-12 |
Not clear |
| Mary E Gerritsen, Robert Soriano, Suya Yang, Constance Zlot, Gladys Ingle, Karen Toy, P Mickey William. Branching out: a molecular fingerprint of endothelial differentiation into tube-like structures generated by Affymetrix oligonucleotide arrays. Microcirculation (New York, N.Y. : 1994). vol 10. issue 1. 2003-12-16. PMID:12610664. |
in the present study, we discuss the identified genes that could be assigned to major functional classes: apoptosis, cytoskeleton, proteases, matrix, and matrix turnover, pumps and transporters, membrane lipid turnover, and junctional molecules or adhesion proteins. |
2003-12-16 |
2023-08-12 |
human |
| Karen Meerovitch, Frédéric Bergeron, Lorraine Leblond, Brigitte Grouix, Cathy Poirier, Monica Bubenik, Laval Chan, Henriette Gourdeau, Terry Bowlin, Giorgio Attard. A novel RGD antagonist that targets both alphavbeta3 and alpha5beta1 induces apoptosis of angiogenic endothelial cells on type I collagen. Vascular pharmacology. vol 40. issue 2. 2003-12-15. PMID:12646396. |
experiments using the matrix metalloproteinase (mmp) inhibitor gm 6001 revealed that cleavage of col was not required for the ability of bch-15046 to induce apoptosis. |
2003-12-15 |
2023-08-12 |
chicken |
| Claudia Seelenmeyer, Sabine Wegehingel, Johannes Lechner, Walter Nicke. The cancer antigen CA125 represents a novel counter receptor for galectin-1. Journal of cell science. vol 116. issue Pt 7. 2003-12-05. PMID:12615972. |
here, we establish a functional link between ca125 and beta-galactoside-binding, cell-surface lectins, which are components of the extracellular matrix implicated in the regulation of cell adhesion, apoptosis, cell proliferation and tumor progression. |
2003-12-05 |
2023-08-12 |
human |
| Fiona Oakley, Nathan Trim, Christothea M Constandinou, Weilan Ye, Alane M Gray, Gretchen Frantz, Kenneth Hillan, Tim Kendall, R Christopher Benyon, Derek A Mann, John P Iredal. Hepatocytes express nerve growth factor during liver injury: evidence for paracrine regulation of hepatic stellate cell apoptosis. The American journal of pathology. vol 163. issue 5. 2003-12-05. PMID:14578185. |
a key feature of recovery from liver fibrosis is hepatic stellate cell (hsc) apoptosis, which serves the dual function of removing the major source of neomatrix and tissue inhibitors of metalloproteinases thereby facilitating matrix degradation. |
2003-12-05 |
2023-08-12 |
cat |