| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Guelaguetza Vazquez-Ortiz, Patricia Pina-Sanchez, Karla Vazquez, Alfonso Duenas, Lucia Taja, Patricia Mendoza, José A Garcia, Mauricio Salced. Overexpression of cathepsin F, matrix metalloproteinases 11 and 12 in cervical cancer. BMC cancer. vol 5. 2006-03-27. PMID:15989693. |
matrix metalloproteinases (mmps) and cathepsins play a central role on the enhancement of tumor-induced angiogenesis, cell migration, proliferation, apoptosis and connective tissue degradation. |
2006-03-27 |
2023-08-12 |
Not clear |
| Orla M Casey, Dermot G Morris, Richard Powell, Joseph M Sreenan, Richard Fitzpatric. Analysis of gene expression in non-regressed and regressed bovine corpus luteum tissue using a customized ovarian cDNA array. Theriogenology. vol 64. issue 9. 2006-03-23. PMID:15953631. |
the differentially expressed genes encoded enzymes involved in steroid biosynthesis and oxygen radical metabolism and proteins involved in extracellular matrix remodeling, apoptosis and cell structure. |
2006-03-23 |
2023-08-12 |
cattle |
| Orla M Casey, Dermot G Morris, Richard Powell, Joseph M Sreenan, Richard Fitzpatric. Analysis of gene expression in non-regressed and regressed bovine corpus luteum tissue using a customized ovarian cDNA array. Theriogenology. vol 64. issue 9. 2006-03-23. PMID:15953631. |
results for five of the differentially expressed genes including matrix gla protein and collagen alpha1(i) (extracellular matrix), glutathione-s-transferase alpha i (oxygen metabolism), clusterin (apoptosis) and scavenger receptor bi (steroid biosynthesis) were confirmed by northern blot analysis and found to be significantly different (p<0.01) between non-regressed and regressed cl tissue. |
2006-03-23 |
2023-08-12 |
cattle |
| Catherine M Robertson, R Todd Allen, Andrew T Pennock, William D Bugbee, David Amie. Upregulation of apoptotic and matrix-related gene expression during fresh osteochondral allograft storage. Clinical orthopaedics and related research. vol 442. 2006-03-23. PMID:16394770. |
loss of chondrocytes via apoptosis is likely a key determinant of osteochondral allograft viability during storage, whereas extracellular matrix degeneration may occur at a later stage. |
2006-03-23 |
2023-08-12 |
human |
| Hesham A Al-Mashat, Suneel Kandru, Rongkun Liu, Yugal Behl, Tesfahun Desta, Dana T Grave. Diabetes enhances mRNA levels of proapoptotic genes and caspase activity, which contribute to impaired healing. Diabetes. vol 55. issue 2. 2006-03-23. PMID:16443785. |
inhibiting apoptosis significantly improved several parameters of healing, including fibroblast density, enhanced mrna levels of collagen i and iii, and increased matrix formation. |
2006-03-23 |
2023-08-12 |
mouse |
| Mark E Obrenovich, Vincent M Monnie. Apoptotic killing of fibroblasts by matrix-bound advanced glycation endproducts. Science of aging knowledge environment : SAGE KE. vol 2005. issue 4. 2006-03-15. PMID:15673817. |
recently reported that cml-rich collagen, representing an artifically aged matrix protein, induces apoptosis in vivo and in fibroblasts. |
2006-03-15 |
2023-08-12 |
Not clear |
| Irving M Shapiro, Christopher S Adams, Theresa Freeman, Vickram Sriniva. Fate of the hypertrophic chondrocyte: microenvironmental perspectives on apoptosis and survival in the epiphyseal growth plate. Birth defects research. Part C, Embryo today : reviews. vol 75. issue 4. 2006-03-15. PMID:16425255. |
with respect to agents that mediate apoptosis, at the chondro-osseous junction, solubilization of mineral and hydrolysis of organic matrix constituents by septoclasts generates high local concentrations of ions, peptides, and glycans, and secreted matrix metalloproteins. |
2006-03-15 |
2023-08-12 |
Not clear |
| U Müller-Ladner, T Pa. [Pathogenesis of RA: more than just immune cells]. Zeitschrift fur Rheumatologie. vol 64. issue 6. 2006-03-14. PMID:16184347. |
in contrast to normal synovial fibroblasts or fibroblasts from patients with osteoarthritis, ra synovial fibroblasts show an upregulation of proto-oncogenes and transcription factors, which in a self-perpetuating manner mediate the expression of adhesion molecules and matrix degrading enzymes, and result in alterations in apoptosis. |
2006-03-14 |
2023-08-12 |
Not clear |
| Christophe F Chantrain, Patrick Henriet, Sonata Jodele, Hervé Emonard, Olivier Feron, Pierre J Courtoy, Yves A DeClerck, Etienne Marbai. Mechanisms of pericyte recruitment in tumour angiogenesis: a new role for metalloproteinases. European journal of cancer (Oxford, England : 1990). vol 42. issue 3. 2006-03-09. PMID:16406506. |
here, we discuss the possibility for mmps to contribute to pericyte recruitment at six levels: (1) direct promotion of pericyte invasion by extracellular matrix degradation; (2) stimulation of pericyte proliferation and protection against apoptosis by modification of the ecm; (3) activation of pericytes through the release of growth factor bound to the ecm; (4) transactivation of angiogenic cell surface receptor; (5) propagation of angiogenic signalling as cofactor; and (6) recruitment of bone marrow-derived stem cells. |
2006-03-09 |
2023-08-12 |
Not clear |
| Neveen Said, Kouros Motame. Absence of host-secreted protein acidic and rich in cysteine (SPARC) augments peritoneal ovarian carcinomatosis. The American journal of pathology. vol 167. issue 6. 2006-03-08. PMID:16314484. |
immunohistochemical analysis of tumor nodules from sparc-null mice revealed higher proliferation and lower apoptosis indices with minimal staining for major extracellular matrix constituents. |
2006-03-08 |
2023-08-12 |
mouse |
| Soraya Labied, Takeshi Kajihara, Patricia A Madureira, Luca Fusi, Marius C Jones, Jenny M Higham, Rana Varshochi, Julia M Francis, Georgia Zoumpoulidou, Abdelkader Essafi, Silvia Fernandez de Mattos, Eric W-F Lam, Jan J Brosen. Progestins regulate the expression and activity of the forkhead transcription factor FOXO1 in differentiating human endometrium. Molecular endocrinology (Baltimore, Md.). vol 20. issue 1. 2006-03-07. PMID:16123151. |
this breakdown of the endometrium in response to falling ovarian progesterone levels is a complex process, characterized by local leukocyte infiltration, expression and activation of matrix metalloproteinases, and apoptosis. |
2006-03-07 |
2023-08-12 |
human |
| Gerhard Fritz, Bernd Kain. Rho GTPases: promising cellular targets for novel anticancer drugs. Current cancer drug targets. vol 6. issue 1. 2006-03-07. PMID:16475973. |
members of the rho family of small gtpases are key regulators of actin reorganization, cell motility, cell-cell and cell-extracellular matrix (ecm) adhesion as well as of cell cycle progression, gene expression and apoptosis. |
2006-03-07 |
2023-08-12 |
Not clear |
| Zezong Gu, Jiankun Cui, Stephen Brown, Rafael Fridman, Shahriar Mobashery, Alex Y Strongin, Stuart A Lipto. A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 27. 2006-02-28. PMID:16000631. |
a highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia. |
2006-02-28 |
2023-08-12 |
mouse |
| Zezong Gu, Jiankun Cui, Stephen Brown, Rafael Fridman, Shahriar Mobashery, Alex Y Strongin, Stuart A Lipto. A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 27. 2006-02-28. PMID:16000631. |
the aberrant, excessive activity of matrix metalloproteinases (mmps), especially mmp-9, contributes directly to neuron apoptosis and brain damage (rosenberg et al., 1996; asahi et al., 2001; gu et al., 2002; horstmann et al., 2003). |
2006-02-28 |
2023-08-12 |
mouse |
| Zezong Gu, Jiankun Cui, Stephen Brown, Rafael Fridman, Shahriar Mobashery, Alex Y Strongin, Stuart A Lipto. A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 27. 2006-02-28. PMID:16000631. |
we determined that mmp-9 degrades the extracellular matrix protein laminin and that this degradation induces neuronal apoptosis in a transient focal cerebral ischemia model in mice. |
2006-02-28 |
2023-08-12 |
mouse |
| Qing Lu, Elizabeth O Harrington, Sharon Round. Apoptosis and lung injury. The Keio journal of medicine. vol 54. issue 4. 2006-02-27. PMID:16452828. |
we have determined that adenosine/homocysteine causes lung vascular endothelial cell apoptosis by inhibition of carboxyl methylation of the small gtpase, ras, through inhibition of isoprenylcysteine carboxyl methyltransferase(icmt) activity, leading to inactivation of ras and the subsequent disruption of focal adhesion complexes, resulting in cell-extracellular matrix detachment and anoikis. |
2006-02-27 |
2023-08-12 |
Not clear |
| Gabriela Rennebeck, Matthew Martelli, Natasha Kypriano. Anoikis and survival connections in the tumor microenvironment: is there a role in prostate cancer metastasis? Cancer research. vol 65. issue 24. 2006-02-23. PMID:16357123. |
normal epithelial and endothelial cells can undergo apoptosis when detached from the extracellular matrix (ecm), via the anoikis phenomenon. |
2006-02-23 |
2023-08-12 |
Not clear |
| Danielle Paixão-Cavalcante, Carmen W van den Berg, Matheus de Freitas Fernandes-Pedrosa, Rute M Gonçalves de Andrade, Denise V Tambourg. Role of matrix metalloproteinases in HaCaT keratinocytes apoptosis induced by loxosceles venom sphingomyelinase D. The Journal of investigative dermatology. vol 126. issue 1. 2006-02-23. PMID:16417218. |
role of matrix metalloproteinases in hacat keratinocytes apoptosis induced by loxosceles venom sphingomyelinase d. envenomation by the spider loxosceles (brown spider) can result in dermonecrosis and severe ulceration. |
2006-02-23 |
2023-08-12 |
human |
| Jianing He, Yiming King, Jin Jiang, Kamran E Safavi, Larz S W Spångberg, Qiang Zh. Enamel matrix derivative inhibits TNF-alpha-induced apoptosis in osteoblastic MC3T3-E1 cells. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. vol 99. issue 6. 2006-02-21. PMID:15897865. |
enamel matrix derivative inhibits tnf-alpha-induced apoptosis in osteoblastic mc3t3-e1 cells. |
2006-02-21 |
2023-08-12 |
Not clear |
| Jianing He, Yiming King, Jin Jiang, Kamran E Safavi, Larz S W Spångberg, Qiang Zh. Enamel matrix derivative inhibits TNF-alpha-induced apoptosis in osteoblastic MC3T3-E1 cells. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. vol 99. issue 6. 2006-02-21. PMID:15897865. |
the purpose of this study was to examine the effect of enamel matrix derivative (emd) on tnf-alpha-induced apoptosis in osteoblastic mc3t3-e1 cells. |
2006-02-21 |
2023-08-12 |
Not clear |