| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Richard Seonghun Nho, Hong Xia, Judy Kahm, Jill Kleidon, Deanna Diebold, Craig A Henk. Role of integrin-linked kinase in regulating phosphorylation of Akt and fibroblast survival in type I collagen matrices through a beta1 integrin viability signaling pathway. The Journal of biological chemistry. vol 280. issue 28. 2005-09-12. PMID:15905178. |
here, we show that ilk activity decreased in response to collagen matrix contraction, which correlated with akt dephosphorylation and induction of fibroblast apoptosis. |
2005-09-12 |
2023-08-12 |
Not clear |
| Richard Seonghun Nho, Hong Xia, Judy Kahm, Jill Kleidon, Deanna Diebold, Craig A Henk. Role of integrin-linked kinase in regulating phosphorylation of Akt and fibroblast survival in type I collagen matrices through a beta1 integrin viability signaling pathway. The Journal of biological chemistry. vol 280. issue 28. 2005-09-12. PMID:15905178. |
in contrast, enforced activation of beta1 integrin by activating antibody preserved ilk and akt activity during collagen matrix contraction, and this is associated with protection from collagen contraction-induced apoptosis. |
2005-09-12 |
2023-08-12 |
Not clear |
| Robert F Foronjy, Becky A Mercer, Mark W Maxfield, Charles A Powell, Jeanine D'Armiento, Yasunori Okad. Structural emphysema does not correlate with lung compliance: lessons from the mouse smoking model. Experimental lung research. vol 31. issue 6. 2005-09-07. PMID:16019987. |
the smoking model generated significant emphysema in a/j mice in the absence of changes in compliance, lung matrix, or apoptosis. |
2005-09-07 |
2023-08-12 |
mouse |
| Ramya Sundararajan, Guanghua Chen, Chandreyee Mukherjee, Eileen Whit. Caspase-dependent processing activates the proapoptotic activity of deleted in breast cancer-1 during tumor necrosis factor-alpha-mediated death signaling. Oncogene. vol 24. issue 31. 2005-09-01. PMID:15824730. |
overexpression of an amino-terminal truncated dbc-1, resembling p120 dbc-1, caused mitochondrial clustering, mitochondrial matrix condensation, and sensitized cells to tnf-alpha-mediated apoptosis. |
2005-09-01 |
2023-08-12 |
human |
| Wei Qiu, Su-Xia Bai, Mei-Rong Zhao, Xiao-Qiu Wu, Yun-Ge Zhao, Qing-Xiang Amy Sang, Yan-Ling Wan. Spatio-temporal expression of matrix metalloproteinase-26 in human placental trophoblasts and fetal red cells during normal placentation. Biology of reproduction. vol 72. issue 4. 2005-08-30. PMID:15601912. |
the processes of implantation and placentation involve the degradation and remodeling of extracellular matrix, cellular proliferation, apoptosis, and differentiation. |
2005-08-30 |
2023-08-12 |
human |
| F Vasaturo, C Malacrino, E Sallusti, G Coppotelli, P Birarelli, A Giuffrida, L Albonici, L Simonelli, A Modesti, M Modesti, S Scarp. Role of extracellular matrix in regulation of staurosporine-induced apoptosis in breast cancer cells. Oncology reports. vol 13. issue 4. 2005-08-26. PMID:15756452. |
role of extracellular matrix in regulation of staurosporine-induced apoptosis in breast cancer cells. |
2005-08-26 |
2023-08-12 |
human |
| F Vasaturo, C Malacrino, E Sallusti, G Coppotelli, P Birarelli, A Giuffrida, L Albonici, L Simonelli, A Modesti, M Modesti, S Scarp. Role of extracellular matrix in regulation of staurosporine-induced apoptosis in breast cancer cells. Oncology reports. vol 13. issue 4. 2005-08-26. PMID:15756452. |
finally, a partial loss of function mutant ras protein that activated only raf pathway, was expressed in mcf7, in order to identify whether the increase of apoptosis induced by extracellular matrix involved the raf/map kinase pathway. |
2005-08-26 |
2023-08-12 |
human |
| R Curi, C J Lagranha, S Q Doi, D F Sellitti, J Procopio, T C Pithon-Curi, M Corless, P Newsholm. Molecular mechanisms of glutamine action. Journal of cellular physiology. vol 204. issue 2. 2005-08-25. PMID:15795900. |
glutamine is the most abundant free amino acid in the body and is known to play a regulatory role in several cell specific processes including metabolism (e.g., oxidative fuel, gluconeogenic precursor, and lipogenic precursor), cell integrity (apoptosis, cell proliferation), protein synthesis, and degradation, contractile protein mass, redox potential, respiratory burst, insulin resistance, insulin secretion, and extracellular matrix (ecm) synthesis. |
2005-08-25 |
2023-08-12 |
Not clear |
| Judith Sendzik, Mehdi Shakibaei, Monika Schäfer-Korting, Ralf Stahlman. Fluoroquinolones cause changes in extracellular matrix, signalling proteins, metalloproteinases and caspase-3 in cultured human tendon cells. Toxicology. vol 212. issue 1. 2005-08-25. PMID:15890441. |
furthermore, time- and concentration-dependent increases of matrix metalloproteinases as well as of the apoptosis marker activated caspase-3 were found. |
2005-08-25 |
2023-08-12 |
human |
| Farshid Saadat, Mohammad Reza Khorramizadeh, Abbas Mirshafie. Apoptotic efficacy and inhibitory effect of dexamethasone on matrix metalloproteinase. Medical science monitor : international medical journal of experimental and clinical research. vol 11. issue 7. 2005-08-25. PMID:15990687. |
there is now accumulating evidence that matrix metalloproteinases and apoptosis may play an important role in inflammation processes. |
2005-08-25 |
2023-08-12 |
Not clear |
| Farshid Saadat, Mohammad Reza Khorramizadeh, Abbas Mirshafie. Apoptotic efficacy and inhibitory effect of dexamethasone on matrix metalloproteinase. Medical science monitor : international medical journal of experimental and clinical research. vol 11. issue 7. 2005-08-25. PMID:15990687. |
this study was undertaken to determine the effect of dexamethasone on apoptosis and matrix metalloproteinase 2 (mmp-2) activity compared with two nonsteroidal anti-inflammatory drugs (nsaids), piroxicam and diclofenac. |
2005-08-25 |
2023-08-12 |
Not clear |
| DeeAnn M Rivera, Brian D Lowe. Molecular remodeling in the failing human heart. Current heart failure reports. vol 2. issue 1. 2005-08-25. PMID:16036045. |
these changes in gene expression are complex and involve contractile proteins, ion channels, ca++ handling, apoptosis, cell metabolism, the extracellular matrix, signal transduction pathways, and growth factors. |
2005-08-25 |
2023-08-12 |
human |
| Robert Zivadino. Steroids and brain atrophy in multiple sclerosis. Journal of the neurological sciences. vol 233. issue 1-2. 2005-08-22. PMID:15882880. |
it has been shown that chronic use of high dose intravenous methylprednisolone (ivmp) in patients with ms may limit brain atrophy progression over the long-term via different immunological mechanisms, including downregulation of adhesion molecule expression on endothelial cells, decreased cytokine and matrix metalloproteinase secretion, decreased autoreactive t-cell-mediated inflammation and t-cell apoptosis induction, blood-brain barrier closure, demyelination inhibition and, possibly, remyelination promotion. |
2005-08-22 |
2023-08-12 |
Not clear |
| Yi-Xun Liu, Fei Gao, Peng Wei, Xin-Lei Chen, Hong-Juan Gao, Ru-Jin Zou, Li-Juan Siao, Fu-Hua Xu, Qing Feng, Kui Liu, Zhao-Yuan H. Involvement of molecules related to angiogenesis, proteolysis and apoptosis in implantation in rhesus monkey and mouse. Contraception. vol 71. issue 4. 2005-08-18. PMID:15792644. |
we have established the well-defined cycling, pseudo-pregnant and pregnant rhesus monkey models, and used these to analyze expression of the common molecules specifically related to angiogenesis, apoptosis or proteolysis, such as vascular endothelial growth factor (vegf) and its receptors kdr, flt-1, flt-4 and flk-1, basic fibroblast growth factor (bfgf) and its receptors flg, transforming growth factor-alpha and beta1 (tgf-a/beta1), and tgf-beta1 receptor type i (tbetar-i) and type ii (tbetar-ii), as well as steroidogenic acute regulatory protein (star), tissue type plasminogen activator/urokinase plasminogen activator/plasminogen activator inhibitor type 1 (tpa/upa/pai-1) and matrix matalloproteinase type 1, -3/tissue inhibitor matalloproteinase type 1, -2, -3 (mmp-1, -3/timp-1, -2, -3), fas/fasl, bcl-2/bax, in the corpus luteum (cl), in the functional layer of the endometrium and in the materno-fetal boundary of the implantation site. |
2005-08-18 |
2023-08-12 |
rat |
| Daryl T-Y Lau, Bruce A Luxon, Shu-Yuan Xiao, Michael R Beard, Stanley M Lemo. Intrahepatic gene expression profiles and alpha-smooth muscle actin patterns in hepatitis C virus induced fibrosis. Hepatology (Baltimore, Md.). vol 42. issue 2. 2005-08-18. PMID:15986378. |
transcripts with increased abundance in stages 1 and 2 fibrosis were associated with oxidative stress, apoptosis, inflammation, proliferation, and matrix degradation, whereas transcripts increased in stages 3 and 4 were associated with fibrogenesis and cellular proliferation. |
2005-08-18 |
2023-08-12 |
Not clear |
| Jian-Jun Li, Yuan-Lin Guo, Yue-Jin Yan. Enhancing anti-inflammatory cytokine IL-10 may be beneficial for acute coronary syndrome. Medical hypotheses. vol 65. issue 1. 2005-08-16. PMID:15893126. |
interluekine-10 (il-10), which is produced by various inflammatory cells, especially macrophages, has multifaceted anti-inflammatory properties, including inhibition of the prototypic pro-inflammatory transcription factor nuclear factor-kappab, leading to suppressed cytokine production, inhibition of matrix degrading metalloproteinase production, reduction of tissue factor expression, inhibition of apoptosis of macrophages and monocytes after infection, and promotion of the phenotypic switch of lymphocytes into the th2 phenotype. |
2005-08-16 |
2023-08-12 |
Not clear |
| Chada S Redd. Protein kinase C and chemical-induced abnormal palate development. Human & experimental toxicology. vol 24. issue 4. 2005-08-11. PMID:15957537. |
the protein kinase c (pkc) family of proteins mediates the action of growth factors and other ligands by activating a network of transcription factors that bind to tre sequences in the promoters of many genes that regulate cell proliferation, differentiation, extracellular matrix synthesis, apoptosis and others in a cell type-, isozyme- and context-specific manner. |
2005-08-11 |
2023-08-12 |
Not clear |
| S Mukaratirw. Prognostic and predictive markers in canine tumours: rationale and relevance. A review. The veterinary quarterly. vol 27. issue 2. 2005-08-10. PMID:16022341. |
the markers are allocated to four groups according to their function: (i) proliferation markers, (ii) apoptosis, (iii) extracellular matrix and cell adhesion molecules, (iv) angiogenesis and (v) cell cycle regulators. |
2005-08-10 |
2023-08-12 |
Not clear |
| Asa Nilsdotter-Augustinsson, Carina Claesson, Per-Eric Lindgren, Helen Lundqvist-Gustafsson, Lena Ohma. Adherence of Staphylococcus epidermidis to extracellular matrix proteins and effects of fibrinogen-bound bacteria on oxidase activity and apoptosis in neutrophils. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. vol 113. issue 5. 2005-08-09. PMID:16011663. |
adherence of staphylococcus epidermidis to extracellular matrix proteins and effects of fibrinogen-bound bacteria on oxidase activity and apoptosis in neutrophils. |
2005-08-09 |
2023-08-12 |
Not clear |
| Haruyo Ichikawa, Yasunari Takada, Akira Murakami, Bharat B Aggarwa. Identification of a novel blocker of I kappa B alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of NF-kappa B-regulated gene products. Journal of immunology (Baltimore, Md. : 1950). vol 174. issue 11. 2005-08-08. PMID:15905586. |
consequently, aca suppressed the expression of tnf-induced nf-kappab-regulated proliferative (e.g., cyclin d1 and c-myc), antiapoptotic (survivin, inhibitor of apoptosis protein-1 (iap1), iap2, x-chromosome-linked iap, bcl-2, bcl-x(l), bfl-1/a1, and flip), and metastatic (cyclooxygenase-2, icam-1, vascular endothelial growth factor, and matrix metalloprotease-9) gene products. |
2005-08-08 |
2023-08-12 |
Not clear |