| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alexander V Ovechkin, Neetu Tyagi, Walter E Rodriguez, Melvin R Hayden, Karni S Moshal, Suresh C Tyag. Role of matrix metalloproteinase-9 in endothelial apoptosis in chronic heart failure in mice. Journal of applied physiology (Bethesda, Md. : 1985). vol 99. issue 6. 2006-01-05. PMID:16081621. |
role of matrix metalloproteinase-9 in endothelial apoptosis in chronic heart failure in mice. |
2006-01-05 |
2023-08-12 |
mouse |
| Alexander V Ovechkin, Neetu Tyagi, Walter E Rodriguez, Melvin R Hayden, Karni S Moshal, Suresh C Tyag. Role of matrix metalloproteinase-9 in endothelial apoptosis in chronic heart failure in mice. Journal of applied physiology (Bethesda, Md. : 1985). vol 99. issue 6. 2006-01-05. PMID:16081621. |
although ventricular remodeling is accompanied by increased matrix metalloproteinase (mmp)-9 activity, it is unclear whether mmp-9 plays a role in endothelial apoptosis in chronic volume overload congestive heart failure. |
2006-01-05 |
2023-08-12 |
mouse |
| Alexander V Ovechkin, Neetu Tyagi, Walter E Rodriguez, Melvin R Hayden, Karni S Moshal, Suresh C Tyag. Role of matrix metalloproteinase-9 in endothelial apoptosis in chronic heart failure in mice. Journal of applied physiology (Bethesda, Md. : 1985). vol 99. issue 6. 2006-01-05. PMID:16081621. |
we tested the hypothesis that, in chronic volume overload, myocardial dysfunction involves endocardial endothelial (ee) apoptosis in response to mmp-9 activation, extracellular matrix accumulation, and endothelium-myocytes uncoupling. |
2006-01-05 |
2023-08-12 |
mouse |
| Yi-Xin Wang, Baby Martin-McNulty, Valdeci da Cunha, Jon Vincelette, Xiangru Lu, Qingping Feng, Meredith Halks-Miller, Mithra Mahmoudi, Miriam Schroeder, Babu Subramanyam, Jih-Lie Tseng, Gary D Deng, Sabine Schirm, Anthony Johns, Katalin Kauser, William P Dole, David R Ligh. Fasudil, a Rho-kinase inhibitor, attenuates angiotensin II-induced abdominal aortic aneurysm in apolipoprotein E-deficient mice by inhibiting apoptosis and proteolysis. Circulation. vol 111. issue 17. 2005-12-27. PMID:15851596. |
in this study, we tested the hypothesis that fasudil, a rho-kinase inhibitor, could attenuate ang ii-induced aaa formation by inhibiting vascular wall apoptosis and extracellular matrix proteolysis. |
2005-12-27 |
2023-08-12 |
mouse |
| Barbara G Heerdt, Michele A Houston, Leonard H Augenlich. The intrinsic mitochondrial membrane potential of colonic carcinoma cells is linked to the probability of tumor progression. Cancer research. vol 65. issue 21. 2005-12-22. PMID:16267009. |
subcloned cell lines with higher deltapsim were more likely to exhibit elevated steady-state levels of vascular endothelial growth factor and matrix metalloproteinase 7, and increased invasive behavior (properties associated with tumor progression), than cells with lower intrinsic deltapsim, whereas cells with lower deltapsim were more likely to respond to the chemopreventive activities of butyrate, including deltapsim dissipation, growth arrest, and apoptosis, than cells with higher deltapsim. |
2005-12-22 |
2023-08-12 |
human |
| Arturo Garcia-Touchard, Timothy D Henry, Giuseppe Sangiorgi, Luigi Giusto Spagnoli, Alessandro Mauriello, Cheryl Conover, Robert S Schwart. Extracellular proteases in atherosclerosis and restenosis. Arteriosclerosis, thrombosis, and vascular biology. vol 25. issue 6. 2005-12-21. PMID:15802622. |
in addition to their matrix degradation capabilities, they have other less well known biologic functions that include angiogenesis, growth factor bioavailability, cytokine modulation, receptor shedding, enhancing cell migration, proliferation, invasion, and apoptosis. |
2005-12-21 |
2023-08-12 |
Not clear |
| John M Stewart, Lajos Gera, Daniel C Chan, Eunice J York, Vitalija Simkeviciene, Paul A Bunn, Laimute Taraseviciene-Stewar. Combination cancer chemotherapy with one compound: pluripotent bradykinin antagonists. Peptides. vol 26. issue 8. 2005-12-21. PMID:15878795. |
these promising multitargeted anti-cancer compounds selectively stimulate apoptosis in cancers and also inhibit both angiogenesis and matrix metalloprotease (mmp) action in treated lung and prostate tumors in nude mice. |
2005-12-21 |
2023-08-12 |
mouse |
| Alexander G Marneros, Thomas Krie. Keloids--clinical diagnosis, pathogenesis, and treatment options. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. vol 2. issue 11. 2005-12-20. PMID:16281608. |
experiments with cells derived from keloid tissue revealed a number of abnormalities in cellular functions, such as in proliferation, apoptosis, or expression of growth factors and extracellular matrix proteins. |
2005-12-20 |
2023-08-12 |
Not clear |
| Anna Trauzold, Christian Röder, Bence Sipos, Kristin Karsten, Alexander Arlt, Ping Jiang, Jose Ignacio Martin-Subero, Daniela Siegmund, Susanne Müerköster, Laia Pagerols-Raluy, Reiner Siebert, Harald Wajant, Holger Kalthof. CD95 and TRAF2 promote invasiveness of pancreatic cancer cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 19. issue 6. 2005-12-14. PMID:15670977. |
introduction of a traf2 expression vector in cd95-sensitive colo357 cells resulted in (i) resistance to cd95-induced apoptosis; (ii) increased constitutive nf-kappab and ap-1 activity; and (iii) higher basal secretion of matrix metalloproteinases (mmps), urokinase-type plasminogen activator (upa), and il-8, leading to increased invasiveness. |
2005-12-14 |
2023-08-12 |
Not clear |
| G Anumanthan, S K Halder, H Osada, T Takahashi, P P Massion, D P Carbone, P K Datt. Restoration of TGF-beta signalling reduces tumorigenicity in human lung cancer cells. British journal of cancer. vol 93. issue 10. 2005-12-14. PMID:16251876. |
members of the transforming growth factor-beta (tgf-beta) family regulate a wide range of biological processes including cell proliferation, migration, differentiation, apoptosis, and extracellular matrix deposition. |
2005-12-14 |
2023-08-12 |
mouse |
| Gillian Hughes, Michael P Murphy, Elizabeth C Ledgerwoo. Mitochondrial reactive oxygen species regulate the temporal activation of nuclear factor kappaB to modulate tumour necrosis factor-induced apoptosis: evidence from mitochondria-targeted antioxidants. The Biochemical journal. vol 389. issue Pt 1. 2005-12-12. PMID:15727562. |
mitovit e {[2-(3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2h-1-benzopyran-2-yl)ethyl]triphenylphosphonium bromide} (vitamin e attached to a lipophilic cation that facilitates accumulation of the antioxidant in the mitochondrial matrix) enhanced tnf-induced apoptosis of u937 cells. |
2005-12-12 |
2023-08-12 |
Not clear |
| Gillian Hughes, Michael P Murphy, Elizabeth C Ledgerwoo. Mitochondrial reactive oxygen species regulate the temporal activation of nuclear factor kappaB to modulate tumour necrosis factor-induced apoptosis: evidence from mitochondria-targeted antioxidants. The Biochemical journal. vol 389. issue Pt 1. 2005-12-12. PMID:15727562. |
tnf caused maximal nuclear translocation of nf-kappab within 15 min, compared with 1 h in cells pretreated with mitovit e. thus the accumulation of an antioxidant within the mitochondrial matrix enhances tnf-induced apoptosis by decreasing or delaying the expression of the protective antiapoptotic proteins. |
2005-12-12 |
2023-08-12 |
Not clear |
| Simone Monika Blattner, Matthias Kretzle. Integrin-linked kinase in renal disease: connecting cell-matrix interaction to the cytoskeleton. Current opinion in nephrology and hypertension. vol 14. issue 4. 2005-12-09. PMID:15931012. |
cellular functions like proliferation, differentiation, migration, morphogenesis and apoptosis are modulated by the extracellular matrix. |
2005-12-09 |
2023-08-12 |
Not clear |
| Chikako Odaka, Shinji Izumiyam. Expression of stromelysin-3 (matrix metalloproteinase-11) in macrophages of murine thymus following thymocyte apoptosis. Cellular immunology. vol 235. issue 1. 2005-12-05. PMID:16165118. |
expression of stromelysin-3 (matrix metalloproteinase-11) in macrophages of murine thymus following thymocyte apoptosis. |
2005-12-05 |
2023-08-12 |
mouse |
| Lesley Ann Smyth, Hugh J M Brad. cMet and Fas receptor interaction inhibits death-inducing signaling complex formation in endothelial cells. Hypertension (Dallas, Tex. : 1979). vol 46. issue 1. 2005-11-29. PMID:15911745. |
endothelial cells undergoing cell matrix detachment, anoikis, are sensitive to fas-mediated apoptosis. |
2005-11-29 |
2023-08-12 |
human |
| Begoña Diosdado, Erica van Oort, Cisca Wijmeng. "Coelionomics": towards understanding the molecular pathology of coeliac disease. Clinical chemistry and laboratory medicine. vol 43. issue 7. 2005-11-22. PMID:16207126. |
four mechanisms, namely apoptosis, oxidative stress, matrix metalloproteinases and dysregulation of proliferation and differentiation, are thought to play a role in the pathophysiology of cd. |
2005-11-22 |
2023-08-12 |
Not clear |
| E Arendt, U Ueberham, R Bittner, R Gebhardt, E Ueberha. Enhanced matrix degradation after withdrawal of TGF-beta1 triggers hepatocytes from apoptosis to proliferation and regeneration. Cell proliferation. vol 38. issue 5. 2005-11-21. PMID:16202037. |
enhanced matrix degradation after withdrawal of tgf-beta1 triggers hepatocytes from apoptosis to proliferation and regeneration. |
2005-11-21 |
2023-08-12 |
mouse |
| S Lísová, J Ehrmann, A Kolek, E Sedláková, Z Kolá. [Immunohistochemical study of the apoptotic and proliferative mechanisms in the intestinal mucosa during coeliac disease]. Ceskoslovenska patologie. vol 41. issue 3. 2005-11-08. PMID:16161453. |
mechanisms leading to morphological changes of the small intestine during coeliac disease are not yet completely recognized, however, two main processes have been suggested recently: remodelling of mucosa by matrix metalloproteinases, and mucosal atrophy by apoptosis. |
2005-11-08 |
2023-08-12 |
Not clear |
| Hossein Ardehali, Brian O'Rourk. Mitochondrial K(ATP) channels in cell survival and death. Journal of molecular and cellular cardiology. vol 39. issue 1. 2005-11-07. PMID:15978901. |
since the discovery of the mitochondrial atp-sensitive potassium channel (mitok(atp)) more than 13 years ago, it has been implicated in the processes of ischemic preconditioning (ipc), apoptosis and mitochondrial matrix swelling. |
2005-11-07 |
2023-08-12 |
Not clear |
| Xuemei Lian, Cong Yan, Yulin Qin, Lana Knox, Tingyu Li, Hong D. Neutral lipids and peroxisome proliferator-activated receptor-{gamma} control pulmonary gene expression and inflammation-triggered pathogenesis in lysosomal acid lipase knockout mice. The American journal of pathology. vol 167. issue 3. 2005-11-07. PMID:16127159. |
among changed genes, matrix metalloproteinase (mmp)-12, apoptosis inhibitor 6 (api-6), erythroblast transformation-specific domain (ets) transcription factor family member spi-c, and oncogene mafb were increased 100-, 70-, 40-, and 10-fold, respectively, in lal-/- lungs versus the wild-type lungs. |
2005-11-07 |
2023-08-12 |
mouse |