| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gunter Wolf, Sheldon Chen, Fuad N Ziyade. From the periphery of the glomerular capillary wall toward the center of disease: podocyte injury comes of age in diabetic nephropathy. Diabetes. vol 54. issue 6. 2005-08-04. PMID:15919782. |
tgf-beta1 causes an increase in mesangial matrix deposition and glomerular basement membrane (gbm) thickening and may promote podocyte apoptosis or detachment. |
2005-08-04 |
2023-08-12 |
Not clear |
| N I Kalinina, Iu A Antropova, A Agrotis, O P il'inskaia, é M Tararak, A Bobi. [Expression, regulation, and pathophysiological role of NAD(P)H oxidases in atherogenesis]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 90. issue 10. 2005-08-02. PMID:15628177. |
significant increase of reactive oxygen species production by vascular cells can lead to progression of atherosclerotic lesions and development of unstable plaques due to triggering the apoptosis of endothelial and smooth muscle cells, expression of matrix metalloproteases and inflammatory cytokines. |
2005-08-02 |
2023-08-12 |
human |
| Ashwini Kucknoor, Vasanthakrishna Mundodi, John F Alderet. Trichomonas vaginalis adherence mediates differential gene expression in human vaginal epithelial cells. Cellular microbiology. vol 7. issue 6. 2005-08-02. PMID:15888089. |
the identified genes were found to encode functional proteins with specific functions associated with cell structure maintenance and extracellular matrix components, proinflammatory molecules and apoptosis. |
2005-08-02 |
2023-08-12 |
human |
| Calogera M Simonaro, Marina D'Angelo, Mark E Haskins, Edward H Schuchma. Joint and bone disease in mucopolysaccharidoses VI and VII: identification of new therapeutic targets and biomarkers using animal models. Pediatric research. vol 57. issue 5 Pt 1. 2005-07-28. PMID:15746260. |
bromodeoxyuridine incorporation studies also revealed that mps chondrocytes proliferated up to 5-fold faster than normal chondrocytes, and released elevated levels of transforming growth factor-beta, presumably to counteract the marked chondrocyte apoptosis and matrix degradation associated with mmp expression. |
2005-07-28 |
2023-08-12 |
Not clear |
| Mélanie Bérubé, Mariève Talbot, Charles Collin, Carine Paquet-Bouchard, Lucie Germain, Sylvain L Guérin, Eric Petitcler. Role of the extracellular matrix proteins in the resistance of SP6.5 uveal melanoma cells toward cisplatin. International journal of oncology. vol 26. issue 2. 2005-07-26. PMID:15645125. |
analysis of cell death by flow cytometry demonstrated that culturing sp6.5 cells in the presence of fn, civ and lm, substantially reduced the percentage of cells undergoing apoptosis after cisplatin treatment when compared with those seeded on a non-permissive matrix. |
2005-07-26 |
2023-08-12 |
Not clear |
| Bindu Menon, Mahipal Singh, Krishna Sing. Matrix metalloproteinases mediate beta-adrenergic receptor-stimulated apoptosis in adult rat ventricular myocytes. American journal of physiology. Cell physiology. vol 289. issue 1. 2005-07-25. PMID:15728709. |
matrix metalloproteinases mediate beta-adrenergic receptor-stimulated apoptosis in adult rat ventricular myocytes. |
2005-07-25 |
2023-08-12 |
rat |
| P Imirzalioĝlu, S Uckan, E E Alaaddinoĝlu, A Haberal, D Ucka. Cigarette smoking and apoptosis. Journal of periodontology. vol 76. issue 5. 2005-07-25. PMID:15898934. |
thus we analyzed soluble fas and nuclear matrix protein (nmp) levels in the saliva of smokers (n = 13) and non-smokers (n = 14) to assess apoptosis. |
2005-07-25 |
2023-08-12 |
human |
| Tamara Tanos, Maria Julia Marinissen, Federico Coluccio Leskow, Daniel Hochbaum, Horacio Martinetto, J Silvio Gutkind, Omar A Cos. Phosphorylation of c-Fos by members of the p38 MAPK family. Role in the AP-1 response to UV light. The Journal of biological chemistry. vol 280. issue 19. 2005-07-12. PMID:15708845. |
among them, the rapid activation of genes coding for two subfamilies of proto-oncoproteins, fos and jun, which constitute the ap-1 transcription factor, plays a key role in the subsequent regulation of expression of genes involved in dna repair, cell proliferation, cell cycle arrest, death by apoptosis, and tissue and extracellular matrix remodeling proteases. |
2005-07-12 |
2023-08-12 |
Not clear |
| In-Hyuk Chung, Sook-Hwan Lee, Kyo-Won Lee, Sang-hee Park, Kwang-Yul Cha, Nam-Soon Kim, Hyang-Sook Yoo, Yong Sung Kim, Suman Le. Gene expression analysis of cultured amniotic fluid cell with Down syndrome by DNA microarray. Journal of Korean medical science. vol 20. issue 1. 2005-07-11. PMID:15716609. |
to analyze differential gene expressions in amniotic fluid (af) cells of ds, we used a dna microarray system to analyze 102 genes, which included 24 genes on chromosome 21, 28 genes related to the function of brain and muscle, 36 genes related to apoptosis, 4 genes related to extracellular matrix, 8 genes related to other molecular function and 2 house-keeping genes. |
2005-07-11 |
2023-08-12 |
human |
| Elizabeth Tafolla, Shaohui Wang, Benita Wong, Jeffrey Leong, Yvonne L Kapil. JNK1 and JNK2 oppositely regulate p53 in signaling linked to apoptosis triggered by an altered fibronectin matrix: JNK links FAK and p53. The Journal of biological chemistry. vol 280. issue 20. 2005-07-08. PMID:15778501. |
jnk1 and jnk2 oppositely regulate p53 in signaling linked to apoptosis triggered by an altered fibronectin matrix: jnk links fak and p53. |
2005-07-08 |
2023-08-12 |
Not clear |
| Elizabeth Tafolla, Shaohui Wang, Benita Wong, Jeffrey Leong, Yvonne L Kapil. JNK1 and JNK2 oppositely regulate p53 in signaling linked to apoptosis triggered by an altered fibronectin matrix: JNK links FAK and p53. The Journal of biological chemistry. vol 280. issue 20. 2005-07-08. PMID:15778501. |
the extracellular matrix regulates many cellular processes, including survival, and alterations in the matrix or in matrix survival signals can trigger apoptosis. |
2005-07-08 |
2023-08-12 |
Not clear |
| Elizabeth Tafolla, Shaohui Wang, Benita Wong, Jeffrey Leong, Yvonne L Kapil. JNK1 and JNK2 oppositely regulate p53 in signaling linked to apoptosis triggered by an altered fibronectin matrix: JNK links FAK and p53. The Journal of biological chemistry. vol 280. issue 20. 2005-07-08. PMID:15778501. |
previously, we showed that an altered fibronectin matrix triggers apoptosis in primary cells via a novel pathway regulated by transcriptionally mediated decreases in p53 and c-myc levels. |
2005-07-08 |
2023-08-12 |
Not clear |
| Eric Meyer, Jean-Yves Vollmer, Raymonde Bovey, Ivan Stamenkovi. Matrix metalloproteinases 9 and 10 inhibit protein kinase C-potentiated, p53-mediated apoptosis. Cancer research. vol 65. issue 10. 2005-07-07. PMID:15899818. |
matrix metalloproteinases 9 and 10 inhibit protein kinase c-potentiated, p53-mediated apoptosis. |
2005-07-07 |
2023-08-12 |
human |
| Krishnamurthy P Gudehithlu, Naila Ahmed, Henry Wu, Natalia O Litbarg, Sandra L Garber, Jose A L Arruda, George Dunea, Ashok K Sing. Antagonism of vascular endothelial growth factor results in microvessel attrition and disorganization of wound tissue. The Journal of laboratory and clinical medicine. vol 145. issue 4. 2005-07-07. PMID:15962838. |
after injection of the vegf receptor antagonist in the fully formed granuloma, the preexisting blood vessels in the middle layer regressed and underwent apoptosis, accompanied by expansion of the extracellular matrix (predominately collagen i) into areas normally devoid of matrix. |
2005-07-07 |
2023-08-12 |
rat |
| John J Bissler, Bradley P Dixo. A mechanistic approach to inherited polycystic kidney disease. Pediatric nephrology (Berlin, Germany). vol 20. issue 5. 2005-07-06. PMID:15719257. |
the dysregulation of renal tubular epithelial cell biology, including cell polarity, cell signaling, proliferation and apoptosis, basement membrane and matrix abnormalities, and fluid transport, has been postulated to contribute to cystogenesis. |
2005-07-06 |
2023-08-12 |
Not clear |
| Haibo Zhao, F Patrick Ross, Steven L Teitelbau. Unoccupied alpha(v)beta3 integrin regulates osteoclast apoptosis by transmitting a positive death signal. Molecular endocrinology (Baltimore, Md.). vol 19. issue 3. 2005-06-28. PMID:15591537. |
consistent with the posture that alpha(v)beta3 occupancy promotes survival, preosteoclasts plated on native collagen, a matrix not recognized by the integrin, undergo apoptosis 4-fold faster than those on the alpha(v)beta3 ligand, vitronectin. |
2005-06-28 |
2023-08-12 |
Not clear |
| Jonathan C Choy, Vivian H Y Hung, Arwen L Hunter, Paul K Cheung, Bruce Motyka, Ing Swie Goping, Tracy Sawchuk, R Chris Bleackley, Thomas J Podor, Bruce M McManus, David J Granvill. Granzyme B induces smooth muscle cell apoptosis in the absence of perforin: involvement of extracellular matrix degradation. Arteriosclerosis, thrombosis, and vascular biology. vol 24. issue 12. 2005-06-21. PMID:15472125. |
granzyme b induces smooth muscle cell apoptosis in the absence of perforin: involvement of extracellular matrix degradation. |
2005-06-21 |
2023-08-12 |
Not clear |
| Amy W Rachfal, David R Brigstoc. Structural and functional properties of CCN proteins. Vitamins and hormones. vol 70. 2005-06-21. PMID:15727802. |
the ccn family currently comprises six members (ccn1-6) that regulate diverse cell functions, including mitogenesis, adhesion, apoptosis, extracellular matrix (ecm) production, growth arrest, and migration. |
2005-06-21 |
2023-08-12 |
Not clear |
| Jolanta M Wodzinsk. Transglutaminases as targets for pharmacological inhibition. Mini reviews in medicinal chemistry. vol 5. issue 3. 2005-06-21. PMID:15777262. |
transglutaminases (tgases), a family of enzymes that catalyze the formation of epsilon-(gamma-glutamyl)lysine isopeptide linkage, play an important physiological role in hemostasis, wound healing, assembly and remodeling of the extracellular matrix, cell signaling and apoptosis. |
2005-06-21 |
2023-08-12 |
human |
| G Astrid Limb, Karl Matter, Gillian Murphy, Alison D Cambrey, Paul N Bishop, Glenn E Morris, Peng T Kha. Matrix metalloproteinase-1 associates with intracellular organelles and confers resistance to lamin A/C degradation during apoptosis. The American journal of pathology. vol 166. issue 5. 2005-06-21. PMID:15855654. |
matrix metalloproteinase-1 associates with intracellular organelles and confers resistance to lamin a/c degradation during apoptosis. |
2005-06-21 |
2023-08-12 |
Not clear |