| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Masanori Ii, Hiroyuki Yamamoto, Yasushi Adachi, Yumiko Maruyama, Yasuhisa Shinomur. Role of matrix metalloproteinase-7 (matrilysin) in human cancer invasion, apoptosis, growth, and angiogenesis. Experimental biology and medicine (Maywood, N.J.). vol 231. issue 1. 2006-02-16. PMID:16380641. |
role of matrix metalloproteinase-7 (matrilysin) in human cancer invasion, apoptosis, growth, and angiogenesis. |
2006-02-16 |
2023-08-12 |
human |
| Philippe Clézardi. Anti-tumour activity of zoledronic acid. Cancer treatment reviews. vol 31 Suppl 3. 2006-02-14. PMID:16225995. |
they not only inhibit proliferation and induce apoptosis in cultured cancer cells, but additionally interfere with adhesion of cancer cells to the bone matrix and inhibit cell migration and invasion. |
2006-02-14 |
2023-08-12 |
Not clear |
| J Tabernero, T Macarulla, F J Ramos, J Baselg. Novel targeted therapies in the treatment of gastric and esophageal cancer. Annals of oncology : official journal of the European Society for Medical Oncology. vol 16. issue 11. 2006-02-09. PMID:15980157. |
these therapeutic strategies include egfr inhibitors, antiangiogenic agents, cell cycle inhibitors, apoptosis promoters and matrix metalloproteinases inhibitors. |
2006-02-09 |
2023-08-12 |
Not clear |
| Sandra L Merklinger, Peter L Jones, Eliana C Martinez, Marlene Rabinovitc. Epidermal growth factor receptor blockade mediates smooth muscle cell apoptosis and improves survival in rats with pulmonary hypertension. Circulation. vol 112. issue 3. 2006-02-09. PMID:16027270. |
we showed in pulmonary artery (pa) organ culture that the mechanism by which elastase inhibitors induce smc apoptosis involves repression of matrix metalloproteinase (mmp) activity and subsequent signaling through alphavbeta3-integrins and epidermal growth factor receptors (egfrs). |
2006-02-09 |
2023-08-12 |
rat |
| Marco Rossi, Andrew M Sharkey, Paola Viganò, Giovina Fiore, Rob Furlong, Pasquale Florio, Guido Ambrosini, Stephen K Smith, Felice Petragli. Identification of genes regulated by interleukin-1beta in human endometrial stromal cells. Reproduction (Cambridge, England). vol 130. issue 5. 2006-02-09. PMID:16264101. |
these cdna arrays were produced containing 15 164 sequence-verified clones, which included genes known to be important in angiogenesis, immune modulators, apoptosis, cell signalling, extra-cellular matrix (ecm) remodelling and cell cycle regulation. |
2006-02-09 |
2023-08-12 |
human |
| Sita Aggarwal, Haruyo Ichikawa, Yasunari Takada, Santosh K Sandur, Shishir Shishodia, Bharat B Aggarwa. Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation. Molecular pharmacology. vol 69. issue 1. 2006-02-07. PMID:16219905. |
such tnf-induced nf-kappab-regulated gene products involved in cellular proliferation [cyclooxygenase-2 (cox-2), cyclin d1, and c-myc], antiapoptosis [inhibitor of apoptosis protein (iap)1, iap2, x-chromosome-linked iap, bcl-2, bcl-x(l), bfl-1/a1, tnf receptor-associated factor 1, and cellular fas-associated death domain protein-like interleukin-1beta-converting enzyme inhibitory protein-like inhibitory protein], and metastasis (vascular endothelial growth factor, matrix metalloproteinase-9, and intercellular adhesion molecule-1) were also down-regulated by curcumin. |
2006-02-07 |
2023-08-12 |
Not clear |
| Suk Keun Lee, Yeon Sook Kim, Sang Shin Lee, Young Joon Lee, In Sun Song, Sang Chul Park, Je Geun Chi, Soo Il Chun. Antisense inhibition of transglutaminase 2 affects development of mouse embryo submandibular gland in organ culture. Archives of oral biology. vol 50. issue 9. 2006-02-03. PMID:15970210. |
tissue transglutaminase (tgase 2) has been implicated in numerous cellular functions, i.e., apoptosis, differentiation, extracellular matrix protein cross-linking and organogenesis. |
2006-02-03 |
2023-08-12 |
mouse |
| Gabriele A Losa, Christian Castell. Nuclear patterns of human breast cancer cells during apoptosis: characterisation by fractal dimension and co-occurrence matrix statistics. Cell and tissue research. vol 322. issue 2. 2006-02-03. PMID:16059703. |
nuclear patterns of human breast cancer cells during apoptosis: characterisation by fractal dimension and co-occurrence matrix statistics. |
2006-02-03 |
2023-08-12 |
human |
| Gabriele A Losa, Christian Castell. Nuclear patterns of human breast cancer cells during apoptosis: characterisation by fractal dimension and co-occurrence matrix statistics. Cell and tissue research. vol 322. issue 2. 2006-02-03. PMID:16059703. |
an analytical strategy combining fractal geometry and grey-level co-occurrence matrix (glcm) statistics was devised to investigate ultrastructural changes in oestrogen-insensitive sk-br3 human breast cancer cells undergoing apoptosis in vitro. |
2006-02-03 |
2023-08-12 |
human |
| Koichi Kozak. [Current concepts of vascular calcification]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics. vol 42. issue 6. 2006-01-31. PMID:16408509. |
besides apoptosis and pi uptake, such proteins as osteoprotegerin (opg), matrix gla protein (mgp), klotho, fetuin-a, and apoe have been shown to negatively affect vascular calcification. |
2006-01-31 |
2023-08-12 |
human |
| Bindu Menon, Mahipal Singh, Robert S Ross, Jennifer N Johnson, Krishna Sing. beta-Adrenergic receptor-stimulated apoptosis in adult cardiac myocytes involves MMP-2-mediated disruption of beta1 integrin signaling and mitochondrial pathway. American journal of physiology. Cell physiology. vol 290. issue 1. 2006-01-27. PMID:16148033. |
recently, we have shown that inhibition of matrix metalloproteinase-2 (mmp-2) inhibits beta-ar-stimulated apoptosis and that the apoptotic effects of mmp-2 are possibly mediated via its interaction with beta1 integrins. |
2006-01-27 |
2023-08-12 |
human |
| Jeremy S Duffield, Peter G Tipping, Tiina Kipari, Jean-François Cailhier, Spike Clay, Richard Lang, Joseph V Bonventre, Jeremy Hughe. Conditional ablation of macrophages halts progression of crescentic glomerulonephritis. The American journal of pathology. vol 167. issue 5. 2006-01-26. PMID:16251406. |
in the presence of macrophages, interstitial myofibroblasts exhibited increased levels of both proliferation and apoptosis, suggesting that macrophages act to support a population of renal myofibroblasts in a high turnover state and in matrix deposition. |
2006-01-26 |
2023-08-12 |
mouse |
| Katja Breitkopf, Stephan Haas, Eliza Wiercinska, Manfred V Singer, Steven Doole. Anti-TGF-beta strategies for the treatment of chronic liver disease. Alcoholism, clinical and experimental research. vol 29. issue 11 Suppl. 2006-01-26. PMID:16344596. |
in parallel, tgf-beta triggers hepatocytes that are strongly responsive for this cytokine, to undergo apoptosis, thereby providing space for hsc proliferation and generation of a collagenous matrix. |
2006-01-26 |
2023-08-12 |
human |
| Viktor Todorovic, Chih-Chiun Chen, Nissim Hay, Lester F La. The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts. The Journal of cell biology. vol 171. issue 3. 2006-01-24. PMID:16275757. |
the matrix protein ccn1 (cyr61) induces apoptosis in fibroblasts. |
2006-01-24 |
2023-08-12 |
Not clear |
| Viktor Todorovic, Chih-Chiun Chen, Nissim Hay, Lester F La. The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts. The Journal of cell biology. vol 171. issue 3. 2006-01-24. PMID:16275757. |
contrary to this paradigm, we show that fibroblast adhesion to the angiogenic matrix protein ccn1 (cyr61) induces apoptosis, whereas endothelial cell adhesion to ccn1 promotes cell survival. |
2006-01-24 |
2023-08-12 |
Not clear |
| Viktor Todorovic, Chih-Chiun Chen, Nissim Hay, Lester F La. The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts. The Journal of cell biology. vol 171. issue 3. 2006-01-24. PMID:16275757. |
these results show that cellular interaction with a specific matrix protein can either induce or suppress apoptosis in a cell type-specific manner and that integrin alpha6beta1-hspgs can function as receptors to induce p53-dependent apoptosis. |
2006-01-24 |
2023-08-12 |
Not clear |
| Jean-Christophe Copin, Marie-Christelle Goodyear, Jeffrey M Gidday, Aarti R Shah, Eduardo Gascon, Alexandre Dayer, Denis M Morel, Yvan Gasch. Role of matrix metalloproteinases in apoptosis after transient focal cerebral ischemia in rats and mice. The European journal of neuroscience. vol 22. issue 7. 2006-01-23. PMID:16197500. |
role of matrix metalloproteinases in apoptosis after transient focal cerebral ischemia in rats and mice. |
2006-01-23 |
2023-08-12 |
mouse |
| Jean-Christophe Copin, Marie-Christelle Goodyear, Jeffrey M Gidday, Aarti R Shah, Eduardo Gascon, Alexandre Dayer, Denis M Morel, Yvan Gasch. Role of matrix metalloproteinases in apoptosis after transient focal cerebral ischemia in rats and mice. The European journal of neuroscience. vol 22. issue 7. 2006-01-23. PMID:16197500. |
the involvement of matrix metalloproteinases (mmps) in cerebral ischemia-induced apoptosis was investigated in a model of transient focal cerebral ischemia in rats treated intracerebroventricularly (i.c.v.) |
2006-01-23 |
2023-08-12 |
mouse |
| Mehdi Shakibaei, Gundula Schulze-Tanzil, Thilo John, Ali Mobasher. Curcumin protects human chondrocytes from IL-l1beta-induced inhibition of collagen type II and beta1-integrin expression and activation of caspase-3: an immunomorphological study. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. vol 187. issue 5-6. 2006-01-23. PMID:16320828. |
at the cellular level, il-1beta activates matrix degrading enzymes, down-regulates expression of matrix components and induces chondrocyte apoptosis. |
2006-01-23 |
2023-08-12 |
human |
| Sergey G Kuznetsov, Thomas C G Bosc. Self/nonself recognition in Cnidaria: contact to allogeneic tissue does not result in elimination of nonself cells in Hydra vulgaris. Zoology (Jena, Germany). vol 106. issue 2. 2006-01-23. PMID:16351896. |
in a previous paper (kuznetsov et al., 2002) we described that cells which accumulate in the contact region of these interspecies grafts are apoptotic and that apoptosis is induced by impaired cell matrix contact. |
2006-01-23 |
2023-08-12 |
Not clear |