| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Liezhen Fu, Akihiro Tomita, Hua Wang, Daniel R Buchholz, Yun-Bo Sh. Transcriptional regulation of the Xenopus laevis Stromelysin-3 gene by thyroid hormone is mediated by a DNA element in the first intron. The Journal of biological chemistry. vol 281. issue 25. 2006-08-11. PMID:16606608. |
the matrix metalloproteinase (mmp) stromelysin-3 (st3) (mmp11) was first isolated as a breast cancer-associated gene and is expressed in diverse human carcinomas and various developmental processes involving apoptosis. |
2006-08-11 |
2023-08-12 |
human |
| Min-Huey Chen, Jue-Long Wang, Chi-Yin Wong, Chung-Chen Yao, Yi-Jane Chen, Ching-Chuan Jian. Relationship of chondrocyte apoptosis to matrix degradation and swelling potential of osteoarthritic cartilage. Journal of the Formosan Medical Association = Taiwan yi zhi. vol 104. issue 4. 2006-08-01. PMID:15909064. |
relationship of chondrocyte apoptosis to matrix degradation and swelling potential of osteoarthritic cartilage. |
2006-08-01 |
2023-08-12 |
Not clear |
| Min-Huey Chen, Jue-Long Wang, Chi-Yin Wong, Chung-Chen Yao, Yi-Jane Chen, Ching-Chuan Jian. Relationship of chondrocyte apoptosis to matrix degradation and swelling potential of osteoarthritic cartilage. Journal of the Formosan Medical Association = Taiwan yi zhi. vol 104. issue 4. 2006-08-01. PMID:15909064. |
the purpose of this study was to investigate the correlation of chondrocyte apoptosis, matrix degradation, and the corruption of collagen architecture in the development of severe swelling of osteoarthritic cartilage. |
2006-08-01 |
2023-08-12 |
Not clear |
| Karin von Wnuck Lipinski, Petra Keul, Nicola Ferri, Susann Lucke, Gerd Heusch, Jens W Fischer, Bodo Levka. Integrin-mediated transcriptional activation of inhibitor of apoptosis proteins protects smooth muscle cells against apoptosis induced by degraded collagen. Circulation research. vol 98. issue 12. 2006-08-01. PMID:16728660. |
apoptosis of smooth muscle cells (smc) and degradation of the extracellular matrix (ecm) have both been implicated in atherosclerotic plaque rupture. |
2006-08-01 |
2023-08-12 |
Not clear |
| Wei-Shu Wang, Po-Min Chen, Huann-Sheng Wang, Wen-Yih Liang, Yeu S. Matrix metalloproteinase-7 increases resistance to Fas-mediated apoptosis and is a poor prognostic factor of patients with colorectal carcinoma. Carcinogenesis. vol 27. issue 5. 2006-07-31. PMID:16474169. |
matrix metalloproteinase-7 increases resistance to fas-mediated apoptosis and is a poor prognostic factor of patients with colorectal carcinoma. |
2006-07-31 |
2023-08-12 |
Not clear |
| L-J Guo, X-H Luo, H Xie, H-D Zhou, L-Q Yuan, M Wang, E-Y Lia. Tissue inhibitor of matrix metalloproteinase-1 suppresses apoptosis of mouse bone marrow stromal cell line MBA-1. Calcified tissue international. vol 78. issue 5. 2006-07-27. PMID:16691494. |
tissue inhibitor of matrix metalloproteinase-1 suppresses apoptosis of mouse bone marrow stromal cell line mba-1. |
2006-07-27 |
2023-08-12 |
mouse |
| Pierre H Vacho. [Cell survival: differences and differentiation]. Medecine sciences : M/S. vol 22. issue 4. 2006-07-25. PMID:16597413. |
the same complex nature applies with regards to anoikis, a form of apoptosis that is largely regulated by integrin-mediated, cell-extracellular matrix interactions. |
2006-07-25 |
2023-08-12 |
human |
| Allen Cheng, Frank Langer, Tom C Nguyen, Marcin Malinowski, Daniel B Ennis, George T Daughters, Neil B Ingels, D Craig Mille. Transmural left ventricular shear strain alterations adjacent to and remote from infarcted myocardium. The Journal of heart valve disease. vol 15. issue 2. 2006-07-25. PMID:16607903. |
alterations in transmural strains could be a trigger for this process, as these changes can produce apoptosis and extracellular matrix disruption. |
2006-07-25 |
2023-08-12 |
Not clear |
| C Burrows, J M P Holly, N J Laurence, E G Vernon, J V Carter, M A Clark, J McIntosh, C McCaig, Z E Winters, C M Perk. Insulin-like growth factor binding protein 3 has opposing actions on malignant and nonmalignant breast epithelial cells that are each reversible and dependent upon cholesterol-stabilized integrin receptor complexes. Endocrinology. vol 147. issue 7. 2006-07-24. PMID:16614079. |
consistent with this we have demonstrated that although igfbp-3 and a non-igf-binding fragment (serine phosphorylation domain peptide) reduced attachment and enhanced apoptosis of hs578t breast cancer cells cultured on collagen or laminin, it promoted their attachment and survival on fibronectin, which is abundant in the matrix of aggressive tumors. |
2006-07-24 |
2023-08-12 |
Not clear |
| Robert A Gatenby, Edward T Gawlinski, Arthur F Gmitro, Brant Kaylor, Robert J Gillie. Acid-mediated tumor invasion: a multidisciplinary study. Cancer research. vol 66. issue 10. 2006-07-18. PMID:16707446. |
this chronic exposure of peritumoral normal tissue to an acidic microenvironment produces toxicity by: (a) normal cell death caused by the collapse of the transmembrane h(+) gradient inducing necrosis or apoptosis and (b) extracellular matrix degradation through the release of cathepsin b and other proteolytic enzymes. |
2006-07-18 |
2023-08-12 |
Not clear |
| Irfan Rahman, Iain Kilt. Antioxidant therapeutic targets in COPD. Current drug targets. vol 7. issue 6. 2006-07-14. PMID:16787173. |
oxidative stress has important consequences for several elements of lung physiology and for the pathogenesis of copd, including oxidative inactivation of antiproteases and surfactants, mucus hypersecretion, membrane lipid peroxidation, alveolar epithelial injury, remodeling of extracellular matrix, and apoptosis. |
2006-07-14 |
2023-08-12 |
Not clear |
| H A Golpon, N F Voelke. The vasculature as a target in the treatment of pulmonary emphysema. Current drug targets. vol 7. issue 6. 2006-07-14. PMID:16787175. |
the interplay between inflammation, matrix proteolysis, oxidative stress and apoptosis might account for the irreversible progression of the disease. |
2006-07-14 |
2023-08-12 |
Not clear |
| M E Taube, X-W Liu, R Fridman, H-R C Ki. TIMP-1 regulation of cell cycle in human breast epithelial cells via stabilization of p27(KIP1) protein. Oncogene. vol 25. issue 21. 2006-07-07. PMID:16407831. |
increasing evidence suggests that tissue inhibitor of metalloproteinases-1 (timp-1) can directly regulate cell growth and apoptosis independent of its matrix metalloproteinases (mmps)-inhibitory activity. |
2006-07-07 |
2023-08-12 |
human |
| Zaiping Liu, Hongbing Li, Mathieu Derouet, Alexander Berezkin, Takehiko Sasazuki, Senji Shirasawa, Kirill Rose. Oncogenic Ras inhibits anoikis of intestinal epithelial cells by preventing the release of a mitochondrial pro-apoptotic protein Omi/HtrA2 into the cytoplasm. The Journal of biological chemistry. vol 281. issue 21. 2006-07-07. PMID:16461771. |
resistance of cancer cells to anoikis, apoptosis induced by cell detachment from the extracellular matrix, is thought to represent a critical feature of the malignant phenotype. |
2006-07-07 |
2023-08-12 |
Not clear |
| Nicola Normanno, William J Gullic. Epidermal growth factor receptor tyrosine kinase inhibitors and bone metastases: different mechanisms of action for a novel therapeutic application? Endocrine-related cancer. vol 13. issue 1. 2006-07-06. PMID:16601275. |
anti-egfr agents have a direct activity on tumour cells in which they produce growth inhibition, apoptosis, and reduced invasive capacity through the inhibition of molecules associated with tissue invasion such as urokinase-type plasminogen activator (upa) and matrix metalloproteinase (mmp)-9. |
2006-07-06 |
2023-08-12 |
Not clear |
| Xiong Zhi Wu, Dan Chen, Guang Ru Xi. Extracellular matrix remodeling in hepatocellular carcinoma: effects of soil on seed? Medical hypotheses. vol 66. issue 6. 2006-06-29. PMID:16504415. |
on the other hand, hepatocarcinoma cells create a permissive soil by extracellular matrix remodeling, result in high proliferation, low differentiation, apoptosis block, invasion and metastasis. |
2006-06-29 |
2023-08-12 |
Not clear |
| Francesco De Luc. Impaired growth plate chondrogenesis in children with chronic illnesses. Pediatric research. vol 59. issue 5. 2006-06-23. PMID:16627871. |
growth plate chondrocyte proliferation, hypertrophy/differentiation, apoptosis, and cartilage matrix synthesis all contribute to chondrogenesis or cartilage formation, a process tightly coupled to the simultaneous remodeling of the cartilage into bone at the metaphyseal border of the growth plate. |
2006-06-23 |
2023-08-12 |
Not clear |
| Francesco Gorreta, Timothy P Runfola, Amy J VanMeter, Dagania Barzaghi, Vikas Chandhoke, Luca Del Giacc. Identification of thioredoxin reductase 1-regulated genes using small interference RNA and cDNA microarray. Cancer biology & therapy. vol 4. issue 10. 2006-06-22. PMID:16096367. |
we identified trxr1-dependent genes with functions related to several cellular processes such as apoptosis (sox4), ubiquitination (ubiquitin d, f-box protein 25), organization of cytoskeletal/extracellular matrix (keratin 19, fibronectin 1) and transport (cystine/glutamate transporter). |
2006-06-22 |
2023-08-12 |
Not clear |
| Ya-Huey Chen, Hua-Lin Wu, Ching Li, Yi-Hsien Huang, Chi-Wu Chiang, Ming-Ping Wu, Li-Wha W. Anti-angiogenesis mediated by angiostatin K1-3, K1-4 and K1-4.5. Involvement of p53, FasL, AKT and mRNA deregulation. Thrombosis and haemostasis. vol 95. issue 4. 2006-06-22. PMID:16601838. |
more than 70% of these genes participate in growth, inflammation, apoptosis, migration and extracellular matrix. |
2006-06-22 |
2023-08-12 |
human |
| Juan Antonio Marchal, Fernando Rodríguez-Serrano, Joaquín Campos, Roberto Madeddu, Houria Boulaiz, Antonio Martínez-Amat, Esmeralda Carrillo, Octavio Caba, José C Prados, Celia Vélez, Consolación Melguizo, Andrea Montella, Antonia Aráneg. Differentiation: an encouraging approach to anticancer therapy. Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia. vol 111. issue 1. 2006-06-22. PMID:16736717. |
cancer is a process in which changes in regulating circuits are produced, such as proliferation control, the balance between cellular survival and programmed cellular death (apoptosis), the communication with neighbouring cells and with the extracellular matrix, angiogenesis, and finally, the migration of the tumoural cell, the invasion and metastasic dissemination. |
2006-06-22 |
2023-08-12 |
Not clear |