| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eleonora Olivotto, Roberta Vitellozzi, Patricia Fernandez, Elisabetta Falcieri, Michela Battistelli, Sabrina Burattini, Annalisa Facchini, Flavio Flamigni, Spartaco Santi, Andrea Facchini, Rosa Maria Borzi\. Chondrocyte hypertrophy and apoptosis induced by GROalpha require three-dimensional interaction with the extracellular matrix and a co-receptor role of chondroitin sulfate and are associated with the mitochondrial splicing variant of cathepsin B. Journal of cellular physiology. vol 210. issue 2. 2007-02-09. PMID:17096385. |
chondrocyte hypertrophy and apoptosis induced by groalpha require three-dimensional interaction with the extracellular matrix and a co-receptor role of chondroitin sulfate and are associated with the mitochondrial splicing variant of cathepsin b. cxcr2 ligands contribute to chondrocyte hypertrophy and apoptosis, important determinants in cartilage pathophysiology. |
2007-02-09 |
2023-08-12 |
human |
| Gillian E Begg, Lyle Carrington, Philippa H Stokes, Jacqueline M Matthews, Merridee A Wouters, Ahsan Husain, Laszlo Lorand, Siiri E Iismaa, Robert M Graha. Mechanism of allosteric regulation of transglutaminase 2 by GTP. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 52. 2007-02-08. PMID:17179049. |
here, we investigated the allosteric mechanism by which gtp inhibits cross-linking activity of transglutaminase 2 (tg2), a multifunctional protein, with postulated roles in receptor signaling, extracellular matrix assembly, and apoptosis. |
2007-02-08 |
2023-08-12 |
Not clear |
| Gisela Schieren, Brigitta Rumberger, Marinella Klein, Clemens Kreutz, Jochen Wilpert, Marcel Geyer, Daniel Faller, Jens Timmer, Ivo Quack, Lars Christian Rump, Gerd Walz, Johannes Donaue. Gene profiling of polycystic kidneys. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. vol 21. issue 7. 2007-02-01. PMID:16520345. |
fluid secretion with cyst expansion and reactive changes in the extracellular matrix composition combined with increased apoptosis and proliferation rates have been implicated in cystogenesis. |
2007-02-01 |
2023-08-12 |
Not clear |
| Kelly A Harradine, Rosemary J Akhurs. Mutations of TGFbeta signaling molecules in human disease. Annals of medicine. vol 38. issue 6. 2007-01-30. PMID:17008304. |
the transforming growth factor beta (tgfbeta) signaling pathway regulates several biological processes including cellular proliferation, differentiation, apoptosis, migration, and extracellular matrix deposition. |
2007-01-30 |
2023-08-12 |
human |
| Inka Brockhausen, Xiaojing Yang, Mark Harriso. Analysis of the glycodynamics of primary osteoblasts and bone cancer cells. Methods in molecular biology (Clifton, N.J.). vol 347. 2007-01-30. PMID:17072013. |
bone cells produce a variety of glycoproteins that contribute to bone health, and function in cell adhesion, stabilizing the extracellular matrix, promoting growth and differentiation, and the induction of apoptosis. |
2007-01-30 |
2023-08-12 |
Not clear |
| Y Yang, T Ikezoe, C Nishioka, K Bandobashi, T Takeuchi, Y Adachi, M Kobayashi, S Takeuchi, H P Koeffler, H Taguch. NFV, an HIV-1 protease inhibitor, induces growth arrest, reduced Akt signalling, apoptosis and docetaxel sensitisation in NSCLC cell lines. British journal of cancer. vol 95. issue 12. 2007-01-30. PMID:17133272. |
hiv-1 protease inhibitor (pi), nelfinavir (nfv) induced growth arrest and apoptosis of nci-h460 and -h520, a549, ebc-1 and abc-1 non-small-cell lung cancer (nsclc) cells in association with upregulation of p21waf1, p27kip1 and p53, and downregulation of bcl-2 and matrix metalloproteinase (mmp)-2 proteins. |
2007-01-30 |
2023-08-12 |
mouse |
| Cory J Xian, Johanna C Cool, Tim Pyragius, Bruce K Foste. Damage and recovery of the bone growth mechanism in young rats following 5-fluorouracil acute chemotherapy. Journal of cellular biochemistry. vol 99. issue 6. 2007-01-23. PMID:16888818. |
therefore, 5-fu chemotherapy affects bone growth directly by inducing apoptosis and inhibiting proliferation at growth plate cartilage and metaphyseal bone; after the acute damage, bone growth mechanism can recover, which is associated with upregulated expression of matrix proteins and growth factors. |
2007-01-23 |
2023-08-12 |
rat |
| Diane Proudfoot, Catherine M Shanaha. Molecular mechanisms mediating vascular calcification: role of matrix Gla protein. Nephrology (Carlton, Vic.). vol 11. issue 5. 2007-01-18. PMID:17014561. |
it potentially acts in several ways to regulate calcium deposition including: (i) binding calcium ions and crystals; (ii) antagonizing bone morphogenetic protein and altering cell differentiation; (iii) binding to extracellular matrix components; and (iv) regulating apoptosis. |
2007-01-18 |
2023-08-12 |
Not clear |
| Paolo Raggi, Cecilia Giachelli, Antonio Bellas. Interaction of vascular and bone disease in patients with normal renal function and patients undergoing dialysis. Nature clinical practice. Cardiovascular medicine. vol 4. issue 1. 2007-01-16. PMID:17180147. |
imbalances of bone mineral metabolism, bone matrix secretion and vascular smooth-muscle-cell apoptosis seem involved in the ossification of the arterial wall in chronic kidney disease, and could explain some of the complex interactions between bone and vascular disease in renal failure. |
2007-01-16 |
2023-08-12 |
Not clear |
| Annarosa Arcangeli, Andrea Becchett. Complex functional interaction between integrin receptors and ion channels. Trends in cell biology. vol 16. issue 12. 2007-01-08. PMID:17064899. |
integrin receptors mediate adhesion of the cell to the extracellular matrix and thereby regulate cell motility, proliferation, differentiation and apoptosis. |
2007-01-08 |
2023-08-12 |
Not clear |
| Z Liu, H Li, X Wu, B H Yoo, S R Yan, A W Stadnyk, T Sasazuki, S Shirasawa, E C LaCasse, R G Korneluk, K V Rose. Detachment-induced upregulation of XIAP and cIAP2 delays anoikis of intestinal epithelial cells. Oncogene. vol 25. issue 59. 2007-01-04. PMID:16799641. |
detachment of normal epithelial cells from the extracellular matrix triggers apoptosis, a phenomenon called anoikis. |
2007-01-04 |
2023-08-12 |
Not clear |
| Hiroyuki Tsutsui, Tomomi Ide, Shintaro Kinugaw. Mitochondrial oxidative stress, DNA damage, and heart failure. Antioxidants & redox signaling. vol 8. issue 9-10. 2007-01-04. PMID:16987026. |
reactive oxygen species induce myocyte hypertrophy, apoptosis, and interstitial fibrosis by activating matrix metalloproteinases. |
2007-01-04 |
2023-08-12 |
Not clear |
| b' Ma\\xc5\\x82gorzata Krzystek-Korpacka, Ma\\xc5\\x82gorzata Matusiewicz, Teresa Bana\\xc5\\x9. [Structure and function of midkine, a novel heparin-binding growth factor]. Postepy higieny i medycyny doswiadczalnej (Online). vol 60. 2006-12-28. PMID:17115009.' |
the paper presents up-to-date views on the biological activity of midkine both at the cellular (mitogenic properties, participation in apoptosis, and cellular migration, adhesion, morphological differentiation, and chemokine synthesis stimulation) and tissue levels (participation in organogenesis, tissue regeneration and protection and in the formation and degradation of extracellular matrix). |
2006-12-28 |
2023-08-12 |
Not clear |
| André S Bachmann, James P Howard, Carl-Wilhelm Voge. Actin-binding protein filamin A is displayed on the surface of human neuroblastoma cells. Cancer science. vol 97. issue 12. 2006-12-19. PMID:16999820. |
our findings suggest new biological functions for filamins, including a role as mediators in anti-nb igm-induced apoptosis, and they add to the growing body of evidence of the interaction of cytoskeletal proteins with the extracellular matrix. |
2006-12-19 |
2023-08-12 |
human |
| M V Patrushev, V E Patrusheva, V A Kasymov, E V Evdokimovskiĭ, T E Ushakova, A I Gazie. [Release of mtDNA from mitochondria and activation of its replication in tissues of irradiated mice]. Tsitologiia. vol 48. issue 8. 2006-12-18. PMID:17147261. |
a sharp decrease in the amount of mtdna copies in the mitochondrial matrix of spleen cells on the first day after irradiation may be considered as apoptosis development. |
2006-12-18 |
2023-08-12 |
mouse |
| Rong-Ping Guo, Chong Zhong, Ming Shi, Chang-Qing Zhang, Wei Wei, Ya-Qi Zhang, Jin-Qing L. Clinical value of apoptosis and angiogenesis factors in estimating the prognosis of hepatocellular carcinoma. Journal of cancer research and clinical oncology. vol 132. issue 9. 2006-12-15. PMID:16763805. |
whereas some studies have indicated that the prognosis of hepatocellular carcinoma (hcc) was correlated to some apoptosis and angiogenesis factors: p53, survivin, matrix metalloproteinases (mmps, including mmp-2 and mmp-9) and vascular endothelial growth factor (vegf), other studies have failed to confirm this. |
2006-12-15 |
2023-08-12 |
Not clear |
| Zi-hui Wang, Ding Yu, Jie Zheng, Yan Che. [Proteome analysis of nuclear matrix proteins during arsenic trioxide induced apoptosis in K562 cells]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences. vol 37. issue 2. 2006-12-12. PMID:15841146. |
[proteome analysis of nuclear matrix proteins during arsenic trioxide induced apoptosis in k562 cells]. |
2006-12-12 |
2023-08-12 |
Not clear |
| Richard Seonghun Nho, Hong Xia, Deanna Diebold, Judy Kahm, Jill Kleidon, Eric White, Craig A Henk. PTEN regulates fibroblast elimination during collagen matrix contraction. The Journal of biological chemistry. vol 281. issue 44. 2006-12-11. PMID:16963781. |
replicating physiologic apoptosis associated with tissue repair, fibroblasts incorporated into type i collagen matrices undergo apoptosis in response to collagen matrix contraction. |
2006-12-11 |
2023-08-12 |
Not clear |
| Richard Seonghun Nho, Hong Xia, Deanna Diebold, Judy Kahm, Jill Kleidon, Eric White, Craig A Henk. PTEN regulates fibroblast elimination during collagen matrix contraction. The Journal of biological chemistry. vol 281. issue 44. 2006-12-11. PMID:16963781. |
however, during subsequent collagen matrix contraction, the level of phosphorylated akt progressively declines, triggering apoptosis. |
2006-12-11 |
2023-08-12 |
Not clear |
| Richard Seonghun Nho, Hong Xia, Deanna Diebold, Judy Kahm, Jill Kleidon, Eric White, Craig A Henk. PTEN regulates fibroblast elimination during collagen matrix contraction. The Journal of biological chemistry. vol 281. issue 44. 2006-12-11. PMID:16963781. |
here we show that pten phosphatase becomes activated during collagen matrix contraction and is responsible for antagonizing phosphatidylinositol 3-kinase activity and promoting a decline in phosphorylated akt and fibroblast apoptosis in response to collagen contraction. |
2006-12-11 |
2023-08-12 |
Not clear |