| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Peter V N Bodine, Barry S Kom. Wnt signaling and osteoblastogenesis. Reviews in endocrine & metabolic disorders. vol 7. issue 1-2. 2007-05-22. PMID:16960757. |
studies of knockout and transgenic mouse models for wnt pathway components like wnt-10b, lrp-5/6, secreted frizzled-related protein-1, dickkopf-2, axin-2 and beta-catenin have demonstrated that canonical signaling modulates most aspects of osteoblast physiology including proliferation, differentiation, bone matrix formation/mineralization and apoptosis as well as coupling to osteoclastogenesis and bone resorption. |
2007-05-22 |
2023-08-12 |
mouse |
| R Zaragozá, A Gimeno, V J Miralles, E R García-Trevijano, R Carmena, C García, M Mata, I R Puertes, L Torres, J R Viñ. Retinoids induce MMP-9 expression through RARalpha during mammary gland remodeling. American journal of physiology. Endocrinology and metabolism. vol 292. issue 4. 2007-05-21. PMID:17164434. |
the aim of this paper was to study the role of ra during weaning, which consists of three events: apoptosis of the secretory cells, degradation of the extracellular matrix, and adipogenesis. |
2007-05-21 |
2023-08-12 |
rat |
| T John, P F Stahel, S J Morgan, G Schulze-Tanzi. Impact of the complement cascade on posttraumatic cartilage inflammation and degradation. Histology and histopathology. vol 22. issue 7. 2007-05-17. PMID:17455152. |
the local inflammatory response contributes to the pathogenesis of osteoarthritis by inducing chondrocyte apoptosis and the de-regulation of chondrocyte matrix remodelling. |
2007-05-17 |
2023-08-12 |
Not clear |
| Oxana Ibraghimov-Beskrovnaya, Nikolay O Bukano. In vitro cystogenesis: the search for drugs antagonizing cyst development. Nephrologie & therapeutique. vol 2 Suppl 2. 2007-05-14. PMID:17373209. |
autosomal dominant polycystic kidney disease (adpkd) cystogenesis has been extensively studied and major characteristic abnormalities were identified including increased proliferation, apoptosis, changes in cellular polarity, abnormal matrix composition and fluid secretion. |
2007-05-14 |
2023-08-12 |
Not clear |
| Wa Xian, Kathryn L Schwertfeger, Jeffrey M Rose. Distinct roles of fibroblast growth factor receptor 1 and 2 in regulating cell survival and epithelial-mesenchymal transition. Molecular endocrinology (Baltimore, Md.). vol 21. issue 4. 2007-05-07. PMID:17284663. |
in contrast, ifgfr2 activation induced cell apoptosis even in the cells in direct contact with the extracellular matrix. |
2007-05-07 |
2023-08-12 |
mouse |
| Pier Paolo Piccaluga, Claudio Agostinelli, Andrea Califano, Maura Rossi, Katia Basso, Simonetta Zupo, Philip Went, Ulf Klein, Pier Luigi Zinzani, Michele Baccarani, Riccardo Dalla Favera, Stefano A Piler. Gene expression analysis of peripheral T cell lymphoma, unspecified, reveals distinct profiles and new potential therapeutic targets. The Journal of clinical investigation. vol 117. issue 3. 2007-05-04. PMID:17304354. |
when compared with normal t cells, ptcls/u display deregulation of functional programs often involved in tumorigenesis (e.g., apoptosis, proliferation, cell adhesion, and matrix remodeling). |
2007-05-04 |
2023-08-12 |
Not clear |
| Muhammad G Kibriya, Farzana Jasmine, Maria Argos, Wendy J Verret, Muhammad Rakibuz-Zaman, Alauddin Ahmed, Faruque Parvez, Habibul Ahsa. Changes in gene expression profiles in response to selenium supplementation among individuals with arsenic-induced pre-malignant skin lesions. Toxicology letters. vol 169. issue 2. 2007-05-03. PMID:17293063. |
when mapped to a biological association network, many of the differentially expressed genes were found to regulate functional classes such as fibroblast growth factor, collagenase, matrix metalloproteinase and stromelysin-1, and thus, considered to affect cellular processes like apoptosis, proliferation and others. |
2007-05-03 |
2023-08-12 |
human |
| Tobias Schmelzle, Arnaud A Mailleux, Michael Overholtzer, Jason S Carroll, Nicole L Solimini, Eric S Lightcap, Ole P Veiby, Joan S Brugg. Functional role and oncogene-regulated expression of the BH3-only factor Bmf in mammary epithelial anoikis and morphogenesis. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 10. 2007-04-24. PMID:17360431. |
the formation of a lumen in three-dimensional mammary epithelial acinar structures in vitro involves selective apoptosis of centrally localized cells that lack matrix attachment. |
2007-04-24 |
2023-08-12 |
mouse |
| Tobias Schmelzle, Arnaud A Mailleux, Michael Overholtzer, Jason S Carroll, Nicole L Solimini, Eric S Lightcap, Ole P Veiby, Joan S Brugg. Functional role and oncogene-regulated expression of the BH3-only factor Bmf in mammary epithelial anoikis and morphogenesis. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 10. 2007-04-24. PMID:17360431. |
similarly, apoptosis is induced by forced detachment of mammary epithelial cells from matrix, a process referred to as anoikis. |
2007-04-24 |
2023-08-12 |
mouse |
| James R Berenson, Lakshmi Rajdev, Michael Brode. Treatment strategies for skeletal complications of cancer. Cancer biology & therapy. vol 5. issue 9. 2007-04-20. PMID:16969118. |
these agents are potent inhibitors of osteoclast activity that bind to the bone matrix, are released during bone resorption, and are subsequently internalized by osteoclasts, where they interfere with biochemical pathways and induce osteoclast apoptosis. |
2007-04-20 |
2023-08-12 |
Not clear |
| Ilpo Koskivirta, Otto Rahkonen, Mikko Mäyränpää, Sari Pakkanen, Michael Husheem, Annele Sainio, Harri Hakovirta, Jukka Laine, Eero Jokinen, Eero Vuorio, Petri Kovanen, Hannu Järveläine. Tissue inhibitor of metalloproteinases 4 (TIMP4) is involved in inflammatory processes of human cardiovascular pathology. Histochemistry and cell biology. vol 126. issue 3. 2007-04-10. PMID:16521002. |
in advanced atherosclerotic lesions, timp4 was detected around necrotic lipid cores, whereas timp3 and caspase 3 resided within and around the core regions, indicating different roles for timp3 and timp4 in inflammation-induced apoptosis and in matrix turnover. |
2007-04-10 |
2023-08-12 |
human |
| F Hess, D Estrugo, A Fischer, C Belka, N Corde. Integrin-linked kinase interacts with caspase-9 and -8 in an adhesion-dependent manner for promoting radiation-induced apoptosis in human leukemia cells. Oncogene. vol 26. issue 10. 2007-04-10. PMID:16936772. |
integrin-mediated adhesion of leukemia cells to extracellular matrix proteins reduces apoptosis following radiation-induced genotoxic injury. |
2007-04-10 |
2023-08-12 |
human |
| James S Forrester, Peter Libb. The inflammation hypothesis and its potential relevance to statin therapy. The American journal of cardiology. vol 99. issue 5. 2007-04-10. PMID:17317382. |
these mediators, including tumor necrosis factor, interleukins, and matrix metalloproteinases and transforming growth factor-beta are also prominent in other chronic progressive diseases characterized by cell apoptosis and tissue fibrosis. |
2007-04-10 |
2023-08-12 |
Not clear |
| Chia-Ning Shen, Anita Marguerie, Chiao-Yun Chien, Clive Dickson, Jonathan M W Slack, David Tos. All-trans retinoic acid suppresses exocrine differentiation and branching morphogenesis in the embryonic pancreas. Differentiation; research in biological diversity. vol 75. issue 1. 2007-04-03. PMID:17244022. |
in contrast, the suppressive effect of ra on exocrine differentiation may be due to a combination of two mechanisms (i) up-regulation of the extracellular matrix component laminin and (ii) enhancement of apoptosis. |
2007-04-03 |
2023-08-12 |
mouse |
| Miao Y Lai, Henry Wing C Leung, Wen H Yang, Wen H Chen, Hong Z Le. Up-regulation of matrix metalloproteinase family gene involvement in ursolic acid-induced human lung non-small carcinoma cell apoptosis. Anticancer research. vol 27. issue 1A. 2007-03-29. PMID:17352226. |
up-regulation of matrix metalloproteinase family gene involvement in ursolic acid-induced human lung non-small carcinoma cell apoptosis. |
2007-03-29 |
2023-08-12 |
human |
| Miao Y Lai, Henry Wing C Leung, Wen H Yang, Wen H Chen, Hong Z Le. Up-regulation of matrix metalloproteinase family gene involvement in ursolic acid-induced human lung non-small carcinoma cell apoptosis. Anticancer research. vol 27. issue 1A. 2007-03-29. PMID:17352226. |
in this study, there was a significant increase in the gene expression of matrix metalloproteinase (mmp)-1, -2 -3, -9 and -10 in h460 cells after treatment with 10 microm ursolic acid for 24 h. under these experimental conditions, it was found that ursolic acid induced h460 cell apoptosis. |
2007-03-29 |
2023-08-12 |
human |
| Miao Y Lai, Henry Wing C Leung, Wen H Yang, Wen H Chen, Hong Z Le. Up-regulation of matrix metalloproteinase family gene involvement in ursolic acid-induced human lung non-small carcinoma cell apoptosis. Anticancer research. vol 27. issue 1A. 2007-03-29. PMID:17352226. |
these results indicated that matrix metalloproteinase family members are involved not only in invasion, but also in apoptosis of cancer cells. |
2007-03-29 |
2023-08-12 |
human |
| Xiaojuan Lin, Xiancheng Chen, Yuquan Wei, Jumei Zhao, Linyu Fan, Yanjun Wen, Hongbo Wu, Xia Zha. Efficient inhibition of intraperitoneal human ovarian cancer growth and prolonged survival by gene transfer of vesicular stomatitis virus matrix protein in nude mice. Gynecologic oncology. vol 104. issue 3. 2007-03-27. PMID:17112567. |
vesicular stomatitis virus (vsv) matrix protein (mp) has been reported to be capable of inducing apoptosis in vitro in the absence of other viral components. |
2007-03-27 |
2023-08-12 |
mouse |
| Catherine C Net. Cranberry and its phytochemicals: a review of in vitro anticancer studies. The Journal of nutrition. vol 137. issue 1 Suppl. 2007-03-27. PMID:17182824. |
possible chemopreventive mechanisms of action by cranberry phytochemicals include induction of apoptosis in tumor cells, reduced ornithine decarboxylase activity, decreased expression of matrix metalloproteinases associated with prostate tumor metastasis, and antiinflammatory activities including inhibition of cyclooxygenases. |
2007-03-27 |
2023-08-12 |
Not clear |
| Céline Van Themsche, Isabelle Mathieu, Sophie Parent, Eric Asseli. Transforming growth factor-beta3 increases the invasiveness of endometrial carcinoma cells through phosphatidylinositol 3-kinase-dependent up-regulation of X-linked inhibitor of apoptosis and protein kinase c-dependent induction of matrix metalloproteinase-9. The Journal of biological chemistry. vol 282. issue 7. 2007-03-26. PMID:17150964. |
transforming growth factor-beta3 increases the invasiveness of endometrial carcinoma cells through phosphatidylinositol 3-kinase-dependent up-regulation of x-linked inhibitor of apoptosis and protein kinase c-dependent induction of matrix metalloproteinase-9. |
2007-03-26 |
2023-08-12 |
human |