| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ewa M Koźma, Andrzej Głowacki, Krystyna Olczyk, Magdalena Cieciersk. Dermatan sulfate remodeling associated with advanced Dupuytren's contracture. Acta biochimica Polonica. vol 54. issue 4. 2008-08-21. PMID:18066404. |
thus, dupuytren's contracture associated ds remodeling may promote the phenomena typical for advanced disease: apoptosis and reduction in cell number as well as the appearance of dense pseudotendinous collagen matrix. |
2008-08-21 |
2023-08-12 |
Not clear |
| Claudia Ulbrich, Kriss Westphal, Sarah Baatout, Markus Wehland, Johann Bauer, Burkhard Flick, Manfred Infanger, Reinhold Kreutz, Sonia Vadrucci, Marcel Egli, Augusto Cogoli, Hanane Derradji, Jessica Pietsch, Martin Paul, Daniela Grim. Effects of basic fibroblast growth factor on endothelial cells under conditions of simulated microgravity. Journal of cellular biochemistry. vol 104. issue 4. 2008-08-20. PMID:18253936. |
microgravity induced early and late apoptosis, extracellular matrix proteins, endothelin-1 (et-1) and tgf-beta(1) expression. |
2008-08-20 |
2023-08-12 |
Not clear |
| Dong Hee Choi, Eun-Mee Kim, Hyo Jin Son, Tong H Joh, Yoon Seong Kim, Donghou Kim, M Flint Beal, Onyou Hwan. A novel intracellular role of matrix metalloproteinase-3 during apoptosis of dopaminergic cells. Journal of neurochemistry. vol 106. issue 1. 2008-08-19. PMID:18397366. |
a novel intracellular role of matrix metalloproteinase-3 during apoptosis of dopaminergic cells. |
2008-08-19 |
2023-08-12 |
Not clear |
| Dong Hee Choi, Eun-Mee Kim, Hyo Jin Son, Tong H Joh, Yoon Seong Kim, Donghou Kim, M Flint Beal, Onyou Hwan. A novel intracellular role of matrix metalloproteinase-3 during apoptosis of dopaminergic cells. Journal of neurochemistry. vol 106. issue 1. 2008-08-19. PMID:18397366. |
we have previously demonstrated that the active form of matrix metalloproteinase-3 (actmmp-3) is released from dopamine(da)rgic neurons undergoing apoptosis. |
2008-08-19 |
2023-08-12 |
Not clear |
| Catherine C Park, Hui J Zhang, Evelyn S Yao, Chong J Park, Mina J Bissel. Beta1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts. Cancer research. vol 68. issue 11. 2008-08-15. PMID:18519702. |
we previously showed that beta(1) integrin inhibitory antibodies (e.g., aiib2) enhance apoptosis and decrease growth in human breast cancer cells in three-dimensional laminin-rich extracellular matrix (lrecm) cultures and in vivo. |
2008-08-15 |
2023-08-12 |
mouse |
| Ana Paula Sassá Benedete, Ana Paula Veras Sobral, Dirce Mary Correia Lima, Leonardo Kamibeppu, Fernando Augusto Soares, Silvia Vanessa Lourenç. Expression of transforming growth factor-beta 1, -beta 2, and -beta 3 in human developing teeth: immunolocalization according to the odontogenesis phases. Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. vol 11. issue 3. 2008-08-12. PMID:18078367. |
transforming growth factor-beta (tgf-beta) is a multifunctional growth factor that has several biological effects in vivo, including control of cell growth and differentiation, cell migration, lineage determination, motility, adhesion, apoptosis, and synthesis and degradation of extracellular matrix, and tgf-beta plays an important role in regulating tissue repair and regeneration. |
2008-08-12 |
2023-08-12 |
human |
| Anke Hartmann, Jennifer Quist, Henning Hamm, Eva-Bettina Bröcker, Peter Fried. Transplantation of autologous keratinocyte suspension in fibrin matrix to chronic venous leg ulcers: improved long-term healing after removal of the fibrin carrier. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. vol 34. issue 7. 2008-08-12. PMID:18384617. |
parallel in vitro culture was used to validate keratinocyte survival and apoptosis in fibrin compared to collagen matrix carrier. |
2008-08-12 |
2023-08-12 |
Not clear |
| Martha R Watson, Karen Wallace, Roben G Gieling, Derek M Manas, Ellis Jaffray, Ronald T Hay, Derek A Mann, Fiona Oakle. NF-kappaB is a critical regulator of the survival of rodent and human hepatic myofibroblasts. Journal of hepatology. vol 48. issue 4. 2008-08-07. PMID:18279996. |
hepatic myofibroblast apoptosis is associated with remodelling of fibrotic extracellular matrix and regression of fibrosis. |
2008-08-07 |
2023-08-12 |
human |
| Brent E Bobick, William M Kuly. Regulation of cartilage formation and maturation by mitogen-activated protein kinase signaling. Birth defects research. Part C, Embryo today : reviews. vol 84. issue 2. 2008-08-06. PMID:18546337. |
endochondral ossification is a highly regulated, multistep cell specification program involving the initial differentiation of prechondrogenic mesenchymal cells into hyaline chondrocytes, terminal differentiation of hyaline chondrocytes into hypertrophic chondrocytes, and finally, apoptosis of hypertrophic chondrocytes followed by bone matrix deposition. |
2008-08-06 |
2023-08-12 |
Not clear |
| Tomasz Skorsk. BCR/ABL, DNA damage and DNA repair: implications for new treatment concepts. Leukemia & lymphoma. vol 49. issue 4. 2008-08-04. PMID:18398719. |
bcr/abl regulates numerous proteins involved in apoptosis, proliferation and cell - cell or cell - extracellular matrix interactions. |
2008-08-04 |
2023-08-12 |
Not clear |
| Nilly Shimony, Idit Avrahami, Raphael Gorodetsky, Gregory Elkin, Keren Tzukert, Lior Zangi, Lilia Levdansky, Lina Krasny, Yosef S Havi. A 3D rotary renal and mesenchymal stem cell culture model unveils cell death mechanisms induced by matrix deficiency and low shear stress. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. vol 23. issue 6. 2008-07-31. PMID:18344240. |
in epithelial and endothelial cells, detachment from the matrix results in anoikis, a form of apoptosis, whereas stromal and cancer cells are often anchorage independent. |
2008-07-31 |
2023-08-12 |
Not clear |
| Murray C H Clarke, Trevor D Littlewood, Nichola Figg, Janet J Maguire, Anthony P Davenport, Martin Goddard, Martin R Bennet. Chronic apoptosis of vascular smooth muscle cells accelerates atherosclerosis and promotes calcification and medial degeneration. Circulation research. vol 102. issue 12. 2008-07-31. PMID:18497329. |
in addition, vsmc apoptosis induced medial expansion, associated with increased elastic lamina breaks, and abnormal matrix deposition reminiscent of cystic medial necrosis in humans. |
2008-07-31 |
2023-08-12 |
mouse |
| Hongwei Shao, Yaohong Tan, Darwin Eton, Zhe Yang, M Georgina Uberti, Sen Li, Andrew Schulick, Hong Y. Statin and stromal cell-derived factor-1 additively promote angiogenesis by enhancement of progenitor cells incorporation into new vessels. Stem cells (Dayton, Ohio). vol 26. issue 5. 2008-07-28. PMID:18308946. |
in vitro mono-treatment with either fluvastatin (100 nm) or sdf-1 (100 ng/ml) facilitated epc proliferation and migration, inhibited epc apoptosis, enhanced expression of matrix metalloproteinase-2 (mmp-2) and -9 (mmp-9), and increased akt phosphorylation and nitric oxide production. |
2008-07-28 |
2023-08-12 |
mouse |
| Alexander Carpinteiro, Claudia Dumitru, Marcus Schenck, Erich Gulbin. Ceramide-induced cell death in malignant cells. Cancer letters. vol 264. issue 1. 2008-07-24. PMID:18353542. |
stimuli that trigger a release of ceramide to mediate apoptosis include cd95, tnf-receptor, dr5, gamma-irradiation, cytotoxic drugs, uv-light, bacteria, viruses, some forms of developmental death, anti-cd20 and disruption of the cell's contact with its matrix, to name a few. |
2008-07-24 |
2023-08-12 |
Not clear |
| H Wang, X M Jiang, J H Xu, J Xu, J X Tong, Y W Wan. The profile of gene expression and role of nuclear factor kappa B on glomerular injury in rats with Thy-1 nephritis. Clinical and experimental immunology. vol 152. issue 3. 2008-07-22. PMID:18422731. |
concomitantly, at 40 min and on day 7, the up-regulation of 341 genes and 250 genes were observed, while 392 genes and 119 genes were down-regulated in thy-1 n. expression of interleukin (il)-1beta, il-6, proliferating cell nuclear antigen, alpha-smooth muscle actin, collagen type iv and excretion of urinary protein was increased in rats with thy-1 n and decreased in pyrrolidine dithiocarbamate-treated rats with thy-1 n. these data indicated that the significant changes in the gene profile were coupled with the pathological changes of thy-1 n, and activation of nf-kappab may contribute to the pathogenesis of gmcs apoptosis, proliferation, extracelluar matrix accumulation and proteinuria in thy-1 n. |
2008-07-22 |
2023-08-12 |
rat |
| Chiara Cenciarelli, Caterina Tanzarella, Ilio Vitale, Claudio Pisano, Pasqualina Crateri, Stefania Meschini, Giuseppe Arancia, Antonio Antocci. The tubulin-depolymerising agent combretastatin-4 induces ectopic aster assembly and mitotic catastrophe in lung cancer cells H460. Apoptosis : an international journal on programmed cell death. vol 13. issue 5. 2008-07-16. PMID:18386182. |
overall, our findings suggest that the maintenance of microtubular integrity plays a relevant role in stabilising the pericentriolar matrix, whose dismantling can be associated with apoptosis after exposure to microtubule depolymerising agents. |
2008-07-16 |
2023-08-12 |
Not clear |
| K N Syrigos, A Zalonis, E Kotteas, Muhammad Wasif Sai. Targeted therapy for oesophageal cancer: an overview. Cancer metastasis reviews. vol 27. issue 2. 2008-07-15. PMID:18224295. |
these agents have targeted mechanisms of action such as: (1) inhibitors of the erbb receptor family, (2) vascular endothelial growth factor (vegf) inhibitors, (3) selective inhibitors of cycloxygenase-2, (4) matrix metalloproteinase inhibitors, (5) cell-cycle regulators, and (6) promoters of apoptosis. |
2008-07-15 |
2023-08-12 |
Not clear |
| Amparo Garcia-Lopez, Lidon Monferrer, Irma Garcia-Alcover, Marta Vicente-Crespo, M Carmen Alvarez-Abril, Ruben D Arter. Genetic and chemical modifiers of a CUG toxicity model in Drosophila. PloS one. vol 3. issue 2. 2008-07-15. PMID:18270582. |
these genes identify putative cellular processes unknown to be altered by cug repeat rna, and they include mrna export factor aly, apoptosis inhibitor thread, chromatin remodelling factor nurf-38, and extracellular matrix structural component viking. |
2008-07-15 |
2023-08-12 |
human |
| Paula Kuvaja, Anne Talvensaari-Mattila, Taina Turpeenniemi-Hujane. High preoperative plasma TIMP-1 is prognostic for early relapse in primary breast carcinoma. International journal of cancer. vol 123. issue 4. 2008-07-15. PMID:18506691. |
in addition to its capacity to inhibit matrix degradation, timp-1 has been shown to promote cell growth and inhibit apoptosis. |
2008-07-15 |
2023-08-12 |
Not clear |
| Bokyung Sung, Manoj K Pandey, Kwang Seok Ahn, Tingfang Yi, Madan M Chaturvedi, Mingyao Liu, Bharat B Aggarwa. Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-kappaBalpha kinase, leading to potentiation of apoptosis. Blood. vol 111. issue 10. 2008-07-10. PMID:18349320. |
we found that this salicylic acid potentiated the apoptosis induced by cytokine and chemotherapeutic agents, which correlated with the down-regulation of various gene products that mediate proliferation (cyclin d1 and cyclooxygenase-2), survival (bcl-2, bcl-xl, cflip, ciap-1, and survivin), invasion (matrix metalloproteinase-9 and intercellular adhesion molecule-1), and angiogenesis (vascular endothelial growth factor), all known to be regulated by the nf-kappab. |
2008-07-10 |
2023-08-12 |
Not clear |