| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mariusz Koda, Mariola Sulkowska, Luiza Kanczuga-Koda, Katarzyna Jarzabek, Stanislaw Sulkowsk. Expression of leptin and its receptor in female breast cancer in relation with selected apoptotic markers. Folia histochemica et cytobiologica. vol 45 Suppl 1. 2008-10-10. PMID:18292831. |
furthermore, leptin induced growth of malignant cells, counteracted apoptosis and stimulated cell migration as well as overexpression of angiogenic factors and degrading enzymes that split network of intercellular matrix. |
2008-10-10 |
2023-08-12 |
human |
| Catherine C Neto, Jon W Amoroso, Anne M Libert. Anticancer activities of cranberry phytochemicals: an update. Molecular nutrition & food research. vol 52 Suppl 1. 2008-10-09. PMID:18504707. |
possible chemopreventive mechanisms of action by cranberry phytochemicals include induction of apoptosis in tumor cells, reduced ornithine decarboxylase activity, decreased expression of matrix metalloproteinases associated with prostate tumor metastasis, and anti-inflammatory activities including inhibition of cyclooxygenases. |
2008-10-09 |
2023-08-12 |
Not clear |
| Ri-ichiroh Manabe, Ko Tsutsui, Tomiko Yamada, Mina Kimura, Itsuko Nakano, Chisei Shimono, Noriko Sanzen, Yutaka Furutani, Tomohiko Fukuda, Yasuko Oguri, Keiko Shimamoto, Daiji Kiyozumi, Yuya Sato, Yoshikazu Sado, Haruki Senoo, Shohei Yamashina, Shiro Fukuda, Jun Kawai, Nobuo Sugiura, Koji Kimata, Yoshihide Hayashizaki, Kiyotoshi Sekiguch. Transcriptome-based systematic identification of extracellular matrix proteins. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 35. 2008-10-06. PMID:18757743. |
extracellular matrix (ecm), which provides critical scaffolds for all adhesive cells, regulates proliferation, differentiation, and apoptosis. |
2008-10-06 |
2023-08-12 |
mouse |
| F Bertucci, B Orsetti, V Nègre, P Finetti, C Rougé, J-C Ahomadegbe, F Bibeau, M-C Mathieu, I Treilleux, J Jacquemier, L Ursule, A Martinec, Q Wang, J Bénard, A Puisieux, D Birnbaum, C Theille. Lobular and ductal carcinomas of the breast have distinct genomic and expression profiles. Oncogene. vol 27. issue 40. 2008-09-30. PMID:18490921. |
supervised analysis identified a 75-gene expression signature that discriminated ilcs from idcs, with many genes involved in cell adhesion, motility, apoptosis, protein folding, extracellular matrix and protein phosphorylation. |
2008-09-30 |
2023-08-12 |
Not clear |
| L B Bondarenko, T T Volodin. [Polyamines and collagenes interaction in different processes of extracellular matrix production and functioning in norm and with pathology]. Ukrains'kyi biokhimichnyi zhurnal (1999 ). vol 79. issue 6. 2008-09-30. PMID:18712107. |
consequences of such tight interaction of collagenes, polyamines, enzymes of their metabolisms during formation and functioning of extracellular matrix are realised not only at a cellular level (proliferation, differentiation, adhesion, apoptosis), but also at the level of the whole organism (immunity, connective tissues and skeleton formation, tumors). |
2008-09-30 |
2023-08-12 |
Not clear |
| D Maixnerová, M Merta, J Reiterová, J Stekrová, R Rysavá, O Viklický, H Obeidová, V Tesa. The influence of two megsin polymorphisms on the progression of IgA nephropathy. Folia biologica. vol 54. issue 2. 2008-09-24. PMID:18498720. |
megsin plays a role in the regulation of a wide variety of processes in mesangial cells, such as matrix metabolism, cell proliferation, and apoptosis. |
2008-09-24 |
2023-08-12 |
human |
| Sylvia Heeneman, Esther Lutgens, Kitty B Schapira, Mat J A P Daemen, Erik A L Biesse. Control of atherosclerotic plaque vulnerability: insights from transgenic mice. Frontiers in bioscience : a journal and virtual library. vol 13. 2008-09-19. PMID:18508661. |
here, we will discuss how atherosclerosis is modified by manipulations in apoptosis, lesional lipid metabolism, inflammatory pathways, matrix remodeling and thrombotic pathways in genetically-engineered mice, emphasizing the insights that have been gained from these studies for the control of plaque vulnerability. |
2008-09-19 |
2023-08-12 |
mouse |
| Shinya Mizuno, Kunio Matsumoto, Toshikazu Nakamur. HGF as a renotrophic and anti-fibrotic regulator in chronic renal disease. Frontiers in bioscience : a journal and virtual library. vol 13. 2008-09-19. PMID:18508717. |
for myofibroblasts, a key cell type in tissue fibrosis, hgf exerted biological activities, including (i) inhibition of growth, (ii) suppression of fibrogenic cytokine expression, and (iii) enhancement of matrix metalloproteinases involved in subsequent apoptosis. |
2008-09-19 |
2023-08-12 |
mouse |
| N E Joo, T Watanabe, C Chen, M Chekenya, W B Stallcup, Y L Kapil. NG2, a novel proapoptotic receptor, opposes integrin alpha4 to mediate anoikis through PKCalpha-dependent suppression of FAK phosphorylation. Cell death and differentiation. vol 15. issue 5. 2008-09-18. PMID:18292781. |
disruption of cell-matrix interactions can lead to anoikis - apoptosis due to loss of matrix contacts. |
2008-09-18 |
2023-08-12 |
human |
| N E Joo, T Watanabe, C Chen, M Chekenya, W B Stallcup, Y L Kapil. NG2, a novel proapoptotic receptor, opposes integrin alpha4 to mediate anoikis through PKCalpha-dependent suppression of FAK phosphorylation. Cell death and differentiation. vol 15. issue 5. 2008-09-18. PMID:18292781. |
ng2 overexpression alone induced apoptosis and, by reducing fak phosphorylation, increased anoikis induced by an altered matrix. |
2008-09-18 |
2023-08-12 |
human |
| M Vogler, D Dinsdale, X-M Sun, K W Young, M Butterworth, P Nicotera, M J S Dyer, G M Cohe. A novel paradigm for rapid ABT-737-induced apoptosis involving outer mitochondrial membrane rupture in primary leukemia and lymphoma cells. Cell death and differentiation. vol 15. issue 5. 2008-09-18. PMID:18309326. |
surprisingly, abt-737 also induces mitochondrial inner membrane permeabilization (mimp) resulting in mitochondrial matrix swelling and rupture of the outer mitochondrial membrane (omm), so permitting the rapid efflux of cytochrome c from mitochondrial cristae and facilitating rapid caspase activation and apoptosis. |
2008-09-18 |
2023-08-12 |
Not clear |
| Galina Gabriely, Thomas Wurdinger, Santosh Kesari, Christine C Esau, Julja Burchard, Peter S Linsley, Anna M Krichevsk. MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. Molecular and cellular biology. vol 28. issue 17. 2008-09-09. PMID:18591254. |
we demonstrate that mir-21 regulates multiple genes associated with glioma cell apoptosis, migration, and invasiveness, including the reck and timp3 genes, which are suppressors of malignancy and inhibitors of matrix metalloproteinases (mmps). |
2008-09-09 |
2023-08-12 |
mouse |
| Yiwen Niu, Ting Xie, Kui Ge, Yuan Lin, Shuliang L. Effects of extracellular matrix glycosylation on proliferation and apoptosis of human dermal fibroblasts via the receptor for advanced glycosylated end products. The American Journal of dermatopathology. vol 30. issue 4. 2008-09-09. PMID:18645306. |
effects of extracellular matrix glycosylation on proliferation and apoptosis of human dermal fibroblasts via the receptor for advanced glycosylated end products. |
2008-09-09 |
2023-08-12 |
human |
| Yiwen Niu, Ting Xie, Kui Ge, Yuan Lin, Shuliang L. Effects of extracellular matrix glycosylation on proliferation and apoptosis of human dermal fibroblasts via the receptor for advanced glycosylated end products. The American Journal of dermatopathology. vol 30. issue 4. 2008-09-09. PMID:18645306. |
glycosylated matrix induced cell cycle arrest and apoptosis of cultured dermal fibroblasts, whereas application of rage-blocking antibodies redressed these changes. |
2008-09-09 |
2023-08-12 |
human |
| Nadja M Meindl-Beinker, Steven Doole. Transforming growth factor-beta and hepatocyte transdifferentiation in liver fibrogenesis. Journal of gastroenterology and hepatology. vol 23 Suppl 1. 2008-08-29. PMID:18336655. |
currently, hepatic stellate cells (hsc) are thought to be the major fibrotic precursor cells that transdifferentiate to fibrogenic, extracellular matrix producing myofibroblasts in inflammatory liver tissue upon transforming growth factor-beta (tgf-beta) signaling, whereas hepatocytes are thought to respond with apoptosis to this cytokine. |
2008-08-29 |
2023-08-12 |
mouse |
| Nicholas S Heaton, Randal A Wolff, Rita L Malinowski, Debra A Hullett, John R Hoc. Antisense to transforming growth factor-beta(1) facilitates the apoptosis of macrophages in rat vein grafts. Journal of vascular research. vol 45. issue 5. 2008-08-28. PMID:18354256. |
transforming growth factor (tgf)-beta(1) has effects on cell proliferation, apoptosis and extracellular matrix synthesis. |
2008-08-28 |
2023-08-12 |
rat |
| Sateesh Kunigal, Sajani S Lakka, Pushpa Joseph, Norman Estes, Jasti S Ra. Matrix metalloproteinase-9 inhibition down-regulates radiation-induced nuclear factor-kappa B activity leading to apoptosis in breast tumors. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 14. issue 11. 2008-08-28. PMID:18519796. |
matrix metalloproteinase-9 inhibition down-regulates radiation-induced nuclear factor-kappa b activity leading to apoptosis in breast tumors. |
2008-08-28 |
2023-08-12 |
Not clear |
| Dominik Lipka, Janusz Boratyńsk. [Metalloproteinases. Structure and function]. Postepy higieny i medycyny doswiadczalnej (Online). vol 62. 2008-08-26. PMID:18614970. |
they are one of the most important proteolitic enzymes which digest components of the extracellular matrix and abundant macromolecules on cell surface and take part in many physiological processes, such as apoptosis or angiogenesis. |
2008-08-26 |
2023-08-12 |
Not clear |
| Xiaohua Shi, Hong Qu, Matthias Kretzler, Chuanyue W. Roles of PINCH-2 in regulation of glomerular cell shape change and fibronectin matrix deposition. American journal of physiology. Renal physiology. vol 295. issue 1. 2008-08-25. PMID:18480182. |
the pinch-1-integrin-linked kinase (ilk)-alpha-parvin (pip) complex plays important roles in the regulation of glomerular cell behavior, including podocyte shape change, apoptosis, and mesangial fibronectin matrix deposition. |
2008-08-25 |
2023-08-12 |
Not clear |
| Gautam Sethi, Kwang Seok Ahn, Bokyung Sung, Bharat B Aggarwa. Pinitol targets nuclear factor-kappaB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis. Molecular cancer therapeutics. vol 7. issue 6. 2008-08-22. PMID:18566231. |
the inhibition of nf-kappab activation thereby led to down-regulation of gene products involved in inflammation (cyclooxygenase-2), proliferation (cyclin d1 and c-myc), invasion (matrix metalloproteinase-9), angiogenesis (vascular endothelial growth factor), and cell survival (ciap1, ciap2, x-linked inhibitor apoptosis protein, bcl-2, and bcl-xl). |
2008-08-22 |
2023-08-12 |
Not clear |