| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Di Sabatino, K M Pickard, D Rampton, L Kruidenier, L Rovedatti, N A B Leakey, G R Corazza, G Monteleone, T T MacDonal. Blockade of transforming growth factor beta upregulates T-box transcription factor T-bet, and increases T helper cell type 1 cytokine and matrix metalloproteinase-3 production in the human gut mucosa. Gut. vol 57. issue 5. 2008-05-13. PMID:18178611. |
the effect of tgfbeta blockade in normal intestinal biopsies grown ex vivo and lamina propria mononuclear cells (lpmcs) on t-bet, a t-box transcription factor required for t helper cell type (th)1 differentiation, interferon gamma (ifn gamma) production, t cell apoptosis and matrix metalloproteinase (mmp)-3 production has therefore been tested. |
2008-05-13 |
2023-08-12 |
human |
| Alireza Gholami, Raïd Kassis, Eléonore Real, Olivier Delmas, Stéphanie Guadagnini, Florence Larrous, Dorothée Obach, Marie-Christine Prevost, Yves Jacob, Hervé Bourh. Mitochondrial dysfunction in lyssavirus-induced apoptosis. Journal of virology. vol 82. issue 10. 2008-05-13. PMID:18321977. |
previous observations have indicated that the matrix proteins (m) of some lyssaviruses induce strong neuronal apoptosis. |
2008-05-13 |
2023-08-12 |
Not clear |
| Haibo Liu, Ru Yang, Babben Tinner, Annam Choudhry, Norbert Schutze, Brahim Chaqou. Cysteine-rich protein 61 and connective tissue growth factor induce deadhesion and anoikis of retinal pericytes. Endocrinology. vol 149. issue 4. 2008-05-06. PMID:18187544. |
inhibition of matrix metalloproteinase-2 had, at least in part, a protective effect against cyr61- and ctgf-induced apoptosis. |
2008-05-06 |
2023-08-12 |
rat |
| F Renò, V Traina, S Gatti, E Battistella, M Canna. Functionalization of a poly(D,L)lactic acid surface with galactose to improve human keratinocyte behavior for artificial epidermis. Biotechnology and bioengineering. vol 100. issue 1. 2008-04-28. PMID:18080343. |
gal is a disaccharide present in the extracellular matrix (ecm) and it is bind by galectines, a family of cell receptors whose activation regulate the cell-matrix interaction and cell growth and apoptosis. |
2008-04-28 |
2023-08-12 |
human |
| Lawrence H Las. Mitochondrial GSH transport and intestinal cell injury: a commentary on "Contribution of mitochondrial GSH transport to matrix GSH status and colonic epithelial cell apoptosis". Free radical biology & medicine. vol 44. issue 5. 2008-04-24. PMID:18036569. |
mitochondrial gsh transport and intestinal cell injury: a commentary on "contribution of mitochondrial gsh transport to matrix gsh status and colonic epithelial cell apoptosis". |
2008-04-24 |
2023-08-12 |
Not clear |
| Magdalena L Circu, Cynthia Rodriguez, Ronald Maloney, Mary Pat Moyer, Tak Yee A. Contribution of mitochondrial GSH transport to matrix GSH status and colonic epithelial cell apoptosis. Free radical biology & medicine. vol 44. issue 5. 2008-04-24. PMID:18267208. |
contribution of mitochondrial gsh transport to matrix gsh status and colonic epithelial cell apoptosis. |
2008-04-24 |
2023-08-12 |
Not clear |
| Vincenzo Sollazzo, Annalisa Palmieri, Furio Pezzetti, Antonio Scarano, Marcella Martinelli, Luca Scapoli, Leo Massari, Giorgio Brunelli, Elisabetta Caramelli, Francesco Carinc. Genetic effect of anatase on osteoblast-like cells. Journal of biomedical materials research. Part B, Applied biomaterials. vol 85. issue 1. 2008-04-15. PMID:17696146. |
they cover a broad range of functional activities: signaling transduction, immunity, cell cycle regulation, lysosomes composition and vesicular transport, cell adhesion, cytoskeleton and extracellular matrix components, proliferation, and apoptosis. |
2008-04-15 |
2023-08-12 |
Not clear |
| Hironobu Suzuki, Norio Amizuka, Kimimitsu Oda, Masaki Noda, Hayato Ohshima, Takeyasu Maed. Involvement of the klotho protein in dentin formation and mineralization. Anatomical record (Hoboken, N.J. : 2007). vol 291. issue 2. 2008-04-15. PMID:18085632. |
the present study aimed to elucidate the altered histology of incisors of klotho-deficient mice-comparing the findings with those from their wild-type littermates, by using immunohistochemistry for alkaline phosphatase (alp), osteopontin, and dentin matrix protein-1 (dmp-1), terminal deoxynucleotidyl transferase-mediated deoxyuridinetriphosphate nick end-labeling (tunel) detection for apoptosis, and electron probe microanalyzer (epma) analysis on calcium (ca), phosphate (p), and magnesium (mg). |
2008-04-15 |
2023-08-12 |
mouse |
| Philip Y Wai, Paul C Ku. Osteopontin: regulation in tumor metastasis. Cancer metastasis reviews. vol 27. issue 1. 2008-04-11. PMID:18049863. |
studies demonstrate that osteopontin mediates the molecular mechanisms which determine metastatic spread, such as prevention of apoptosis, extracellular matrix proteolysis and remodeling, cell migration, evasion of host-immune cells and neovascularization. |
2008-04-11 |
2023-08-12 |
Not clear |
| Shigeru Kobayashi, Adam Meir, Jill Urba. Effect of cell density on the rate of glycosaminoglycan accumulation by disc and cartilage cells in vitro. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 26. issue 4. 2008-04-08. PMID:17985391. |
although gag production can be increased somewhat by use of higher cell densities, the consequent fall in concentration of oxygen and other nutrients in the center of three-dimensional constructs slows metabolism and leads to apoptosis and cell death, which again limits the rate that the cells can produce matrix. |
2008-04-08 |
2023-08-12 |
Not clear |
| T M Järvinen, P Kanninen, L Jeskanen, S Koskenmies, J Panelius, T Hasan, A Ranki, U Saarialho-Ker. Matrix metalloproteinases as mediators of tissue injury in different forms of cutaneous lupus erythematosus. The British journal of dermatology. vol 157. issue 5. 2008-04-07. PMID:17854363. |
matrix metalloproteinases (mmps) contribute to tissue destruction, regeneration, inflammation and apoptosis and several of them are upregulated by ultraviolet (uv) radiation in skin. |
2008-04-07 |
2023-08-12 |
Not clear |
| Thimios A Mitsiadis, Cosimo De Bari, Imad Abou. Apoptosis in developmental and repair-related human tooth remodeling: a view from the inside. Experimental cell research. vol 314. issue 4. 2008-04-07. PMID:18054913. |
apoptosis is a key phenomenon in the regulation of the life span of odontoblasts, which are responsible for dentin matrix production of the teeth. |
2008-04-07 |
2023-08-12 |
human |
| Ka Chen, Yizeng Tu, Yongjun Zhang, Harry C Blair, Lin Zhang, Chuanyue W. PINCH-1 regulates the ERK-Bim pathway and contributes to apoptosis resistance in cancer cells. The Journal of biological chemistry. vol 283. issue 5. 2008-04-02. PMID:18063582. |
we report here that pinch-1, a cytoplasmic component of cell-extracellular matrix adhesions, is required for protection of multiple types of cancer cells from apoptosis. |
2008-04-02 |
2023-08-12 |
Not clear |
| Linda Gombos, József Kardos, András Patthy, Péter Medveczky, László Szilágyi, András Málnási-Csizmadia, László Grá. Probing conformational plasticity of the activation domain of trypsin: the role of glycine hinges. Biochemistry. vol 47. issue 6. 2008-04-01. PMID:18193894. |
trypsin-like serine proteases play essential roles in diverse physiological processes such as hemostasis, apoptosis, signal transduction, reproduction, immune response, matrix remodeling, development, and differentiation. |
2008-04-01 |
2023-08-12 |
Not clear |
| Götz von Wichert, Denis Krndija, Heidrun Schmid, Georg von Wichert, Georg Haerter, Guido Adler, Thomas Seufferlein, Michael P Sheet. Focal adhesion kinase mediates defects in the force-dependent reinforcement of initial integrin-cytoskeleton linkages in metastatic colon cancer cell lines. European journal of cell biology. vol 87. issue 1. 2008-03-28. PMID:17904248. |
micro-environmental clues, including the biophysical interpretation of the extracellular matrix, are critical to proliferation, apoptosis and migration. |
2008-03-28 |
2023-08-12 |
human |
| Karin Jäger, Heinz Fischer, Erwin Tschachler, Leopold Eckhar. Terminal differentiation of nail matrix keratinocytes involves up-regulation of DNase1L2 but is independent of caspase-14 expression. Differentiation; research in biological diversity. vol 75. issue 10. 2008-03-27. PMID:17490414. |
nail matrix keratinocytes lacked processed caspase-3, a marker of apoptosis, and did not express caspase-14, a protease up-regulated during terminal differentiation of epidermal keratinocytes. |
2008-03-27 |
2023-08-12 |
Not clear |
| Alirio J Melende. Sphingosine kinase signalling in immune cells: potential as novel therapeutic targets. Biochimica et biophysica acta. vol 1784. issue 1. 2008-03-27. PMID:17913601. |
binding of s1p to these receptors trigger an wide range of cellular responses including proliferation, enhanced extracellular matrix assembly, stimulation of adherent junctions, formation of actin stress fibres, and inhibition of apoptosis induced by either ceramide or growth factor withdrawal. |
2008-03-27 |
2023-08-12 |
Not clear |
| B Espina, M Liang, R G G Russell, P A Hulle. Regulation of bim in glucocorticoid-mediated osteoblast apoptosis. Journal of cellular physiology. vol 215. issue 2. 2008-03-25. PMID:18064628. |
bim was also upregulated in osteoblasts undergoing apoptosis in response to serum deprivation and matrix detachment. |
2008-03-25 |
2023-08-12 |
human |
| Judit Marsillach, Natàlia Ferré, Jordi Camps, Francesc Riu, Anna Rull, Jorge Jove. Moderately high folic acid supplementation exacerbates experimentally induced liver fibrosis in rats. Experimental biology and medicine (Maywood, N.J.). vol 233. issue 1. 2008-03-17. PMID:18156304. |
in some of the time periods analyzed, alterations were observed in the expression of genes related to apoptosis (b-cell leukemia/lymphoma 2, inhibitor of apoptosis 2) and to fibrosis (procollagen i, matrix metalloproteinase 7). |
2008-03-17 |
2023-08-12 |
rat |
| Feijun Luo, Rifat Hamoudi, David G Brooks, Charles E Patek, Mark J Arend. Stem cell gene expression changes induced specifically by mutated K-ras. Gene expression. vol 14. issue 2. 2008-03-12. PMID:18257393. |
these expression data may explain, at least in part, some neoplasia-related aspects of the phenotypic changes brought about in this es cell line by mutated k-ras, in that upregulation of cell growth-related proteins and dna-associated proteins is consistent with increased proliferation; upregulation of certain apoptosis-related proteins is consistent with a greater susceptibility to dna damage-induced apoptosis; and downregulation of structural proteins, extracellular matrix components, secretory proteins and receptors is consistent with a less differentiated phenotype. |
2008-03-12 |
2023-08-12 |
mouse |