| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jeffrey C Horowitz, David S Rogers, Richard H Simon, Thomas H Sisson, Victor J Thannicka. Plasminogen activation induced pericellular fibronectin proteolysis promotes fibroblast apoptosis. American journal of respiratory cell and molecular biology. vol 38. issue 1. 2008-02-05. PMID:17656680. |
plasminogen, which was activated to plasmin by fibroblasts, also induced fibronectin proteolysis and fibroblast apoptosis, both of which were blocked by alpha2-antiplasmin but not by inhibition of matrix metalloproteinase activity. |
2008-02-05 |
2023-08-12 |
mouse |
| Ian J Frew, Wilhelm Kre. Multitasking by pVHL in tumour suppression. Current opinion in cell biology. vol 19. issue 6. 2008-02-05. PMID:18006292. |
however, growing evidence indicates that tumour suppression by pvhl also involves the control of a wide variety of hifalpha-independent processes including microtubule dynamics, primary cilium maintenance, cell proliferation, neuronal apoptosis, extracellular matrix deposition and responses to dna damage. |
2008-02-05 |
2023-08-12 |
Not clear |
| Ahmed Ashour Ahmed, Anthony D Mills, Ashraf E K Ibrahim, Jillian Temple, Cherie Blenkiron, Maria Vias, Charlie E Massie, N Gopalakrishna Iyer, Adam McGeoch, Robin Crawford, Barbara Nicke, Julian Downward, Charles Swanton, Stephen D Bell, Helena M Earl, Ronald A Laskey, Carlos Caldas, James D Brento. The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel. Cancer cell. vol 12. issue 6. 2008-02-05. PMID:18068629. |
the extracellular matrix (ecm) can induce chemotherapy resistance via akt-mediated inhibition of apoptosis. |
2008-02-05 |
2023-08-12 |
Not clear |
| Mark A Carlson, Amy K Prall, Jeremiah J Gum. RNA interference in human foreskin fibroblasts within the three-dimensional collagen matrix. Molecular and cellular biochemistry. vol 306. issue 1-2. 2008-01-29. PMID:17657589. |
consistent with prediction, knockdown of fak induced apoptosis in the fibroblast-populated collagen matrix. |
2008-01-29 |
2023-08-12 |
human |
| Maneli Mozaffarieh, Josef Flamme. Is there more to glaucoma treatment than lowering IOP? Survey of ophthalmology. vol 52 Suppl 2. 2008-01-29. PMID:17998043. |
inhibition of matrix metalloproteinase-9 inhibits apoptosis of retinal ganglion cells and tissue remodeling. |
2008-01-29 |
2023-08-12 |
Not clear |
| Takashi Miyake, Motokuni Aoki, Hisao Masaki, Tomio Kawasaki, Masako Oishi, Kazusaburo Kataoka, Toshio Ogihara, Yasufumi Kaneda, Ryuichi Morishit. Regression of abdominal aortic aneurysms by simultaneous inhibition of nuclear factor kappaB and ets in a rabbit model. Circulation research. vol 101. issue 11. 2008-01-25. PMID:17885220. |
interestingly, significant preservation of elastic fibers was observed with chimeric decoy odn treatment, accompanied by a reduction of matrix metalloproteinase-2 and -9 and induction of macrophage apoptosis. |
2008-01-25 |
2023-08-12 |
human |
| Ling Yang, Denise McBurney, Shou-Ching Tang, Sara G Carlson, Walter E Horto. A novel role for Bcl-2 associated-athanogene-1 (Bag-1) in regulation of the endoplasmic reticulum stress response in mammalian chondrocytes. Journal of cellular biochemistry. vol 102. issue 3. 2008-01-17. PMID:17546604. |
chondrocytes respond to endoplasmic reticulum (er) stress with decreased expression of extracellular matrix proteins, and prolonged er stress leads to chondrocyte apoptosis. |
2008-01-17 |
2023-08-12 |
Not clear |
| Rod A Rahimi, Edward B Leo. TGF-beta signaling: a tale of two responses. Journal of cellular biochemistry. vol 102. issue 3. 2008-01-17. PMID:17729308. |
transforming growth factor-beta (tgf-beta) regulates a wide variety of cellular processes including cell growth, apoptosis, differentiation, migration, and extracellular matrix production among others. |
2008-01-17 |
2023-08-12 |
Not clear |
| Ramkumar Menon, Stephen J Fortunat. Infection and the role of inflammation in preterm premature rupture of the membranes. Best practice & research. Clinical obstetrics & gynaecology. vol 21. issue 3. 2008-01-10. PMID:17448730. |
in this chapter we review the role of inflammatory mediators (cytokines and matrix metalloproteinases), and programmed cell death (apoptosis) in preterm labor with no rom and preterm labor with pprom to delineate the differences in pathways between the two conditions. |
2008-01-10 |
2023-08-12 |
Not clear |
| Anne M Goodwi. In vitro assays of angiogenesis for assessment of angiogenic and anti-angiogenic agents. Microvascular research. vol 74. issue 2-3. 2008-01-08. PMID:17631914. |
means of quantifying endothelial cell matrix degradation, migration, proliferation, apoptosis and morphogenesis are discussed, as are embryoid body, aortic ring and metatarsal assays of vessel outgrowth. |
2008-01-08 |
2023-08-12 |
Not clear |
| Kerstin Foitzik, Edo Hoting, Thomas Förster, Paolo Pertile, Ralf Pau. L-carnitine-L-tartrate promotes human hair growth in vitro. Experimental dermatology. vol 16. issue 11. 2008-01-07. PMID:17927577. |
also, ct prolonged the duration of anagen vi, down regulated apoptosis (as measured by tunel assay) and up regulated proliferation (as measured by ki67 immunohistology) of hair matrix keratinocytes (p < 0.5). |
2008-01-07 |
2023-08-12 |
human |
| Amit Verma, Kapil Meht. Tissue transglutaminase-mediated chemoresistance in cancer cells. Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy. vol 10. issue 4-5. 2008-01-03. PMID:17662645. |
tg2 is the most diverse and ubiquitous member of the transglutaminase family of proteins that is implicated to play a role in apoptosis, wound healing, cell migration, cell attachment, cell growth, angiogenesis, and matrix assembly. |
2008-01-03 |
2023-08-12 |
Not clear |
| b' M Magaraggia, L Marigo, A Pagnan, G Jori, A Vison\\xc3\\xa. Porphyrin-photosensitized processes: their applications in the prevention of arterial restenosis. Cardiovascular & hematological agents in medicinal chemistry. vol 5. issue 4. 2008-01-03. PMID:17979690.' |
extension of these investigations to an in vivo rabbit model showed that znpc mainly accumulated in the media layer, where pdt induces the main damage through cellular depletion due to apoptosis of smc, changes in the extracellular matrix with generation of a barrier to cellular migration, and acceleration of re-endothelization. |
2008-01-03 |
2023-08-12 |
rabbit |
| Hye-Ryun Kang, Chun Geun Lee, Robert J Homer, Jack A Elia. Semaphorin 7A plays a critical role in TGF-beta1-induced pulmonary fibrosis. The Journal of experimental medicine. vol 204. issue 5. 2008-01-02. PMID:17485510. |
tgf-beta(1) stimulated sema 7a via a largely smad 3-independent mechanism and stimulated sema 7a receptors, matrix proteins, ccn proteins, fibroblast growth factor 2, interleukin 13 receptor components, proteases, antiprotease, and apoptosis regulators via smad 2/3-independent and sema 7a-dependent mechanisms. |
2008-01-02 |
2023-08-12 |
Not clear |
| Sahin Coban, Osman Yüksel, Muhammed Cem Koçkar, Seyfettin Köklü, Omer Basar, Hüseyin Tutkak, Necati Ormec. The significance of serum transforming growth factor beta 1 in detecting of gastric and colon cancers. Hepato-gastroenterology. vol 54. issue 77. 2007-12-27. PMID:17708279. |
tgf-beta1 is a growth factor with wide ranging effects on proliferation, differentiation, immune suppression, apoptosis and matrix remodeling. |
2007-12-27 |
2023-08-12 |
Not clear |
| Gretchen A Repasky, Yixing Zhou, Staeci Morita, Channing J De. Ras-mediated intestinal epithelial cell transformation requires cyclooxygenase-2-induced prostaglandin E2 signaling. Molecular carcinogenesis. vol 46. issue 12. 2007-12-20. PMID:17477350. |
finally, we found that pge2 stimulated the activation of ras and erk, but not akt, and reduced matrix deprivation-induced apoptosis, in untransformed epithelial cells. |
2007-12-20 |
2023-08-12 |
Not clear |
| Alex Y Hui, Scott L Friedma. Molecular basis of hepatic fibrosis. Expert reviews in molecular medicine. vol 5. issue 5. 2007-12-18. PMID:14987408. |
major advances include: (1) elucidation of the effects (and signalling pathways) of key cytokines on hscs; (2) understanding the transcriptional regulation of hsc activation; (3) characterisation of matrix proteases and their inhibitors; (4) demonstration of apoptosis as an important event in the resolution of hepatic fibrosis, and identification of its mediators;(5) elucidation of the complex and dynamic interaction between hscs and matrix; and (6) understanding the role of other cellular elements in hepatic fibrosis and their interaction with hscs. |
2007-12-18 |
2023-08-12 |
Not clear |
| William Macne. Pathogenesis of chronic obstructive pulmonary disease. Clinics in chest medicine. vol 28. issue 3. 2007-12-18. PMID:17720039. |
other processes, such as failure to resolve inflammation, abnormal cell repair, apoptosis, abnormal cellular maintenance programs, extracellular matrix destruction (protease/antiprotease imbalance), and oxidative stress (oxidant/antioxidant imbalance) also have a role. |
2007-12-18 |
2023-08-12 |
Not clear |
| Mei G Sun, James Williams, Cristina Munoz-Pinedo, Guy A Perkins, Joshua M Brown, Mark H Ellisman, Douglas R Green, Terrence G Fre. Correlated three-dimensional light and electron microscopy reveals transformation of mitochondria during apoptosis. Nature cell biology. vol 9. issue 9. 2007-12-17. PMID:17721514. |
we have identified a remodelling of the inner mitochondrial membrane into many separate vesicular matrix compartments that accompanies release of proteins; however, this remodelling is not required for efficient release of cytochrome c. swelling occurs only late in apoptosis after release of cytochrome c and loss of the mitochondrial membrane potential. |
2007-12-17 |
2023-08-12 |
Not clear |
| E Zeldich, R Koren, M Dard, C Nemcovsky, M Weinre. Enamel matrix derivative protects human gingival fibroblasts from TNF-induced apoptosis by inhibiting caspase activation. Journal of cellular physiology. vol 213. issue 3. 2007-12-14. PMID:17607712. |
enamel matrix derivative protects human gingival fibroblasts from tnf-induced apoptosis by inhibiting caspase activation. |
2007-12-14 |
2023-08-12 |
human |