| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qi Fu Li, Yan Bin Zheng, Hai Bo Yang, Song Lin Shi, Zhen Li Zhao, Jin An Che. [Changes of nuclear matrix proteins during apoptosis of human osteosarcoma MG-63 cells induced by curcumin]. Fen zi xi bao sheng wu xue bao = Journal of molecular cell biology. vol 41. issue 6. 2009-03-17. PMID:19137819. |
this study suggests that the induced apoptosis of carcinoma cells is accompanied with changes of nuclear matrix proteins, and confirms the presence of some specific nuclear matrix proteins associated with carcinoma cell growth, apoptosis and the associated signal transduction pathways in induced apoptosis of carcinoma cells. |
2009-03-17 |
2023-08-12 |
human |
| Qi Fu Li, Yan Bin Zheng, Hai Bo Yang, Song Lin Shi, Zhen Li Zhao, Jin An Che. [Changes of nuclear matrix proteins during apoptosis of human osteosarcoma MG-63 cells induced by curcumin]. Fen zi xi bao sheng wu xue bao = Journal of molecular cell biology. vol 41. issue 6. 2009-03-17. PMID:19137819. |
it provides proofs and a new way to study the mechanisms of gene expression carcinogenesis which reveal the relationship between configuration and composition of nuclear matrix and cell apoptosis. |
2009-03-17 |
2023-08-12 |
human |
| Ruta Aldonyte, Aldonyte Ruta, Mark Brantly, Brantly Mark, Edward Block, Block Edward, Jawaharlal Patel, Patel Jawaharlal, Jianliang Zhang, Zhang Jianlian. Nuclear localization of active matrix metalloproteinase-2 in cigarette smoke-exposed apoptotic endothelial cells. Experimental lung research. vol 35. issue 1. 2009-03-12. PMID:19191105. |
this suggests a novel function of mmp-2 in the degradation of the nuclear matrix in cs-induced endothelial apoptosis. |
2009-03-12 |
2023-08-12 |
Not clear |
| Aurea Gomez-Duran, Jose M Carvajal-Gonzalez, Sonia Mulero-Navarro, Belen Santiago-Josefat, Alvaro Puga, Pedro M Fernandez-Salguer. Fitting a xenobiotic receptor into cell homeostasis: how the dioxin receptor interacts with TGFbeta signaling. Biochemical pharmacology. vol 77. issue 4. 2009-03-06. PMID:18812170. |
transforming growth factor beta (tgfbeta) is an extracellular cytokine that regulates such critical cellular responses as proliferation, apoptosis, differentiation, angiogenesis and migration, and it is assumed that the latency-associated protein ltbp-1 plays a relevant role in tgfbeta targeting and activation in the extracellular matrix (ecm). |
2009-03-06 |
2023-08-12 |
human |
| Frank Y Ma, Jian Liu, A Richard Kitching, Carl L Manthey, David J Nikolic-Paterso. Targeting renal macrophage accumulation via c-fms kinase reduces tubular apoptosis but fails to modify progressive fibrosis in the obstructed rat kidney. American journal of physiology. Renal physiology. vol 296. issue 1. 2009-03-06. PMID:18987110. |
complete inhibition of renal macrophage accumulation prevented upregulation of the macrophage-associated proinflammatory mediators, tumor necrosis factor (tnf)-alpha and matrix metalloproteinase-12, and significantly reduced tubular apoptosis. |
2009-03-06 |
2023-08-12 |
rat |
| Nathaniel B Goldstein, Widya U Johannes, Agnessa V Gadeliya, Matthew R Green, Mayumi Fujita, David A Norris, Yiqun G Shellma. Active N-Ras and B-Raf inhibit anoikis by downregulating Bim expression in melanocytic cells. The Journal of investigative dermatology. vol 129. issue 2. 2009-02-27. PMID:18668139. |
in this study, we investigated how n-ras(q61k) and b-raf(v600e) contribute to melanoma's resistance to apoptosis induced by detachment from the extracellular matrix (anoikis). |
2009-02-27 |
2023-08-12 |
Not clear |
| b' Bal\\xc3\\xa1zs I T\\xc3\\xb3th, Tam\\xc3\\xa1s G\\xc3\\xa9czy, Zolt\\xc3\\xa1n Griger, Anik\\xc3\\xb3 D\\xc3\\xb3zsa, Holger Seltmann, L\\xc3\\xa1szl\\xc3\\xb3 Kov\\xc3\\xa1cs, L\\xc3\\xa1szl\\xc3\\xb3 Nagy, Christos C Zouboulis, Ralf Paus, Tam\\xc3\\xa1s B\\xc3\\xadr\\xc3\\xb. Transient receptor potential vanilloid-1 signaling as a regulator of human sebocyte biology. The Journal of investigative dermatology. vol 129. issue 2. 2009-02-27. PMID:18769453.' |
in human pilosebaceous units, we had shown that trpv1 stimulation inhibits hair shaft elongation and matrix keratinocyte proliferation, and induces premature hair follicle regression and keratinocyte apoptosis. |
2009-02-27 |
2023-08-12 |
human |
| Fang Liu, Chih-Chang Wei, Shyh-Jong Wu, Isabelle Chenier, Shao-Ling Zhang, Janos G Filep, Julie R Ingelfinger, John S D Cha. Apocynin attenuates tubular apoptosis and tubulointerstitial fibrosis in transgenic mice independent of hypertension. Kidney international. vol 75. issue 2. 2009-02-27. PMID:18923387. |
untreated transgenic mice had significant elevations of their systolic blood pressure, albuminuria, reactive oxygen species production, nadph oxidase activity, tubular apoptosis, active caspase-3, bax, transforming growth factor-beta1, plasminogen activator inhibitor-1, extracellular matrix proteins, collagen type iv, and phosphorylated p47phox expression compared to untreated non-transgenic mice. |
2009-02-27 |
2023-08-12 |
mouse |
| Wenjie Jiao, Jing Xu, Jinsheng Zheng, Yi Shen, Lesheng Lin, Jian L. Elevation of circulating big endothelin-1: an independent prognostic factor for tumor recurrence and survival in patients with esophageal squamous cell carcinoma. BMC cancer. vol 8. 2009-02-20. PMID:19014602. |
endothelin(et) axis plays a key role in many tumor progression and metastasis via various mechanisms such as angiogenesis, mediating extracellular matrix degradation and inhibition of apoptosis. |
2009-02-20 |
2023-08-12 |
Not clear |
| Arnaud Carpentier, Filoména Conti, Matthieu Carrière, Lynda Aoudjehane, Céline Miroux, Olivier Moralès, Yvon Calmus, Hervé Groux, Claude Auriault, Véronique Pancré, Nadira Delhem, Philippe Podevi. Analysis of gene transcription in sera during chronic hepatitis C infection. Journal of medical virology. vol 81. issue 3. 2009-02-16. PMID:19152403. |
a comparison of gene transcription by gene involved in t- and b-cell markers, adhesion molecules, apoptosis, liver matrix turnover and inflammation, revealed comparable, significant correlations between serum and liver, (r(2) = 0.30, r(2) = 0.60, r(2) = 0.51, r(2) = 0.51, r(2) = 0.26, and r(2) = 0.61 respectively). |
2009-02-16 |
2023-08-12 |
Not clear |
| Fuad N Ziyadeh, Gunter Wol. Pathogenesis of the podocytopathy and proteinuria in diabetic glomerulopathy. Current diabetes reviews. vol 4. issue 1. 2009-02-13. PMID:18220694. |
decreased podocyte number and/or density as a result of apoptosis or detachment, gbm thickening with altered matrix composition, and a reduction in nephrin protein in the slit diaphragm with podocyte foot process effacement, all comprise the principal features of diabetic podocytopathy that clinically manifests as albuminuria and proteinuria. |
2009-02-13 |
2023-08-12 |
Not clear |
| John F Lechner, Rashmeet K Reen, Alan A Dombkowski, Daniela Cukovic, Sridevi Salagrama, Li-Shu Wang, Gary D Stone. Effects of a black raspberry diet on gene expression in the rat esophagus. Nutrition and cancer. vol 60 Suppl 1. 2009-02-12. PMID:19003582. |
among the upregulated genes are genes associated with cellular matrix, signaling cascades, transcription regulation, apoptosis, metabolism, and intriguingly, contraction. |
2009-02-12 |
2023-08-12 |
rat |
| Matti Laaksonen, Juho Suojanen, Sini Nurmenniemi, Esa Läärä, Timo Sorsa, Tuula Sal. The enamel matrix derivative (Emdogain) enhances human tongue carcinoma cells gelatinase production, migration and metastasis formation. Oral oncology. vol 44. issue 8. 2009-02-05. PMID:18061521. |
emd had no effect on hsc-3 cell proliferation or apoptosis and only a limited effect on cell attachment to various extracellular matrix components. |
2009-02-05 |
2023-08-12 |
mouse |
| Tomohiro Aoki, Hiroharu Kataoka, Ryota Ishibashi, Kazuhiko Nozaki, Nobuo Hashimot. Gene expression profile of the intima and media of experimentally induced cerebral aneurysms in rats by laser-microdissection and microarray techniques. International journal of molecular medicine. vol 22. issue 5. 2009-02-03. PMID:18949379. |
these data suggest that cerebral aneurysmal formation and progression are closely related to vascular inflammation, degeneration of extracellular matrix and apoptosis. |
2009-02-03 |
2023-08-12 |
rat |
| Rong-Guo Wang, Wei Zhou, Yong-Dong Zhan. [Study on the progress of the mechanism of TGF-beta in the scarring and the effect of TCM]. Zhongguo gu shang = China journal of orthopaedics and traumatology. vol 21. issue 2. 2009-01-28. PMID:19105500. |
tgf-beta is a member of cytokine family, involving cell proliferation, migration, differentiation and apoptosis, which subsequently trigger extracellular matrix (ecm) deposite and collagen overproduction. |
2009-01-28 |
2023-08-12 |
Not clear |
| Eva Fischer-Fodor, Natalia Moldovan, Piroska Virag, Olga Soritau, Ioana Brie, Peter Lönnecke, Evamarie Hey-Hawkins, Luminita Silaghi-Dumitresc. The CellScan technology for in vitro studies on novel platinum complexes with organoarsenic ligands. Dalton transactions (Cambridge, England : 2003). issue 45. 2009-01-26. PMID:19002325. |
the detection of cell viability and apoptosis is possible, based on the transformations that occur in the cytoplasm matrix of tumour cells influenced by cytotoxic compounds. |
2009-01-26 |
2023-08-12 |
Not clear |
| Vitaly Balan, Pratima Nangia-Makker, Ann G Schwartz, Young Suk Jung, Larry Tait, Victor Hogan, Tirza Raz, Yi Wang, Zeng Quan Yang, Gen Sheng Wu, Yongjun Guo, Huixiang Li, Judith Abrams, Fergus J Couch, Wilma L Lingle, Ricardo V Lloyd, Stephen P Ethier, Michael A Tainsky, Avraham Ra. Racial disparity in breast cancer and functional germ line mutation in galectin-3 (rs4644): a pilot study. Cancer research. vol 68. issue 24. 2009-01-15. PMID:19074869. |
we report a functional germline mutation (polymorphism) in the galectin-3 gene at position 191 (rs4644) substituting proline with histidine (p64h), which results in susceptibility to matrix metalloproteinase cleavage and acquisition of resistance to drug-induced apoptosis. |
2009-01-15 |
2023-08-12 |
Not clear |
| Nadine Rohwer, Martina Welzel, Katjana Daskalow, David Pfander, Bertram Wiedenmann, Katharina Detjen, Thorsten Crame. Hypoxia-inducible factor 1alpha mediates anoikis resistance via suppression of alpha5 integrin. Cancer research. vol 68. issue 24. 2009-01-15. PMID:19074877. |
the ability of transformed epithelial cells to initiate the metastatic cascade relies on their ability to escape anoikis, a default program of apoptosis induction following loss of integrin anchoring to the extracellular matrix. |
2009-01-15 |
2023-08-12 |
human |
| Herman Yee, Ting-An Yie, Judith Goldberg, Kam Meng Tchou Wong, William N Ro. Immunohistochemical study of fibrosis and adenocarcinoma in dominant-negative p53 transgenic mice exposed to chrysotile asbestos and benzo(a)pyrene. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. vol 27. issue 4. 2009-01-13. PMID:19105532. |
immunostains for proteins related to apoptosis, fibrogenesis, matrix remodeling and inflammation were performed. |
2009-01-13 |
2023-08-12 |
mouse |
| Steven B Abramso. Nitric oxide in inflammation and pain associated with osteoarthritis. Arthritis research & therapy. vol 10 Suppl 2. 2009-01-12. PMID:19007427. |
experiments have demonstrated that no plays a catabolic role in the development of oa and mediates the inflammatory response, is involved in the degradation of matrix metalloproteinases, inhibits the synthesis of both collagen and proteoglycans, and helps to mediate apoptosis. |
2009-01-12 |
2023-08-12 |
human |