| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gillian Murphy, Hideaki Nagas. Progress in matrix metalloproteinase research. Molecular aspects of medicine. vol 29. issue 5. 2008-11-24. PMID:18619669. |
they are involved in modifying matrix structure, growth factor availability and the function of cell surface signalling systems, with consequent effects on cellular differentiation, proliferation and apoptosis. |
2008-11-24 |
2023-08-12 |
Not clear |
| Masao Koda, Yukio Someya, Yutaka Nishio, Ryo Kadota, Chikato Mannoji, Tomohiro Miyashita, Akihiko Okawa, Atsushi Murata, Masashi Yamazak. Brain-derived neurotrophic factor suppresses anoikis-induced death of Schwann cells. Neuroscience letters. vol 444. issue 2. 2008-11-18. PMID:18672025. |
anoikis is a type of apoptosis due to the detachment from the extracellular matrix and neighboring cells. |
2008-11-18 |
2023-08-12 |
rat |
| Benita Krivicka-Uzkurele, Mara Pilmane, Ilze Akot. Barx1, growth factors and apoptosis in facial tissue of children with clefts. Stomatologija. vol 10. issue 2. 2008-11-18. PMID:18708738. |
growth factors and genes play an important role in tissue growth, differentiation and induction and upregulation of growth factors, apoptosis and matrix metalloproteinases might be involved in pathogenesis of facial clefts. |
2008-11-18 |
2023-08-12 |
Not clear |
| Anthony N Imudia, Sanjeev Kumar, Ghassan M Saed, Michael P Diamon. Pathogenesis of Intra-abdominal and pelvic adhesion development. Seminars in reproductive medicine. vol 26. issue 4. 2008-11-18. PMID:18756406. |
major pathways that play significant roles in the healing process of peritoneal damage leading to adhesion development are the fibrinolytic system, extracellular matrix deposition, growth factor and cytokines, cell adhesion molecules, angiogenesis, apoptosis and proliferation, and remesothelialization. |
2008-11-18 |
2023-08-12 |
Not clear |
| L Oslejsková, M Grigorian, S Gay, M Neidhart, L Senol. The metastasis associated protein S100A4: a potential novel link to inflammation and consequent aggressive behaviour of rheumatoid arthritis synovial fibroblasts. Annals of the rheumatic diseases. vol 67. issue 11. 2008-11-12. PMID:18056757. |
cancer promoting properties for s100a4 have been demonstrated, particularly through its regulation of cell motility, proliferation and apoptosis, as well as by stimulation of angiogenesis and remodelling of the extracellular matrix. |
2008-11-12 |
2023-08-12 |
Not clear |
| b' H K Ea, V Monceau, E Camors, M Cohen-Solal, D Charlemagne, F Liot\\xc3\\xa. Annexin 5 overexpression increased articular chondrocyte apoptosis induced by basic calcium phosphate crystals. Annals of the rheumatic diseases. vol 67. issue 11. 2008-11-12. PMID:18218665.' |
in advanced osteoarthritis, cartilage shows chondrocyte apoptosis, overexpression of annexin 5 (a5) and bcp crystal deposition within matrix vesicles. |
2008-11-12 |
2023-08-12 |
Not clear |
| Ajaikumar B Kunnumakkara, Haruyo Ichikawa, Preetha Anand, Chiramel J Mohankumar, Padmanabhan S Hema, Mangalam S Nair, Bharat B Aggarwa. Coronarin D, a labdane diterpene, inhibits both constitutive and inducible nuclear factor-kappa B pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis. Molecular cancer therapeutics. vol 7. issue 10. 2008-11-12. PMID:18852134. |
coronarin d also inhibited the nf-kappab-regulated gene products involved in cell survival (inhibitor of apoptosis protein 1, bcl-2, survivin, and tumor necrosis factor receptor-associated factor-2), proliferation (c-myc, cyclin d1, and cyclooxygenase-2), invasion (matrix metalloproteinase-9), and angiogenesis (vascular endothelial growth factor). |
2008-11-12 |
2023-08-12 |
Not clear |
| Chen Huang, Li-Ying Liu, Zong-Fang Li, Pei Wang, Lei Ni, Li-Ping Song, De-Hui Xu, Tu-Sheng Son. Effects of small interfering RNAs targeting MAPK1 on gene expression profile in HeLa cells as revealed by microarray analysis. Cell biology international. vol 32. issue 9. 2008-11-10. PMID:18539490. |
the results showed that expressions of 181 genes were altered by sirna-2 and were divided into two groups: (i) one group showed downregulation by sirna-2, including the proliferation associated genes, small g protein, cytoskeleton associated protein and extracellular matrix associated protein; and (ii) the other group showed upregulation by sirna-2, including interferon response genes, oas family, trim family and apoptosis associated genes. |
2008-11-10 |
2023-08-12 |
Not clear |
| Jean-François Cailhier, Isabelle Sirois, Patrick Laplante, Stéphanie Lepage, Marc-André Raymond, Nathalie Brassard, Alexandre Prat, Renato V Iozzo, Alexey V Pshezhetsky, Marie-Josée Héber. Caspase-3 activation triggers extracellular cathepsin L release and endorepellin proteolysis. The Journal of biological chemistry. vol 283. issue 40. 2008-11-04. PMID:18658137. |
we showed previously that extracellular matrix proteolysis is triggered by the apoptosis of endothelial cells (ec), resulting in the release of an anti-apoptotic c-terminal fragment of endorepellin (lg3). |
2008-11-04 |
2023-08-12 |
Not clear |
| C Britt Carlson, Kristin A Gunderson, Deane F Moshe. Mutations targeting intermodular interfaces or calcium binding destabilize the thrombospondin-2 signature domain. The Journal of biological chemistry. vol 283. issue 40. 2008-11-04. PMID:18682400. |
thrombospondins (thbss) are a family of secreted calcium-binding glycoproteins with roles in angiogenesis, cell motility, apoptosis, cytoskeletal organization, and extracellular matrix organization. |
2008-11-04 |
2023-08-12 |
Not clear |
| Paul W M Feda. Paracrine effects of cell transplantation: modifying ventricular remodeling in the failing heart. Seminars in thoracic and cardiovascular surgery. vol 20. issue 2. 2008-11-04. PMID:18707639. |
these paracrine signals may provide beneficial effects by stimulating angiogenesis, limiting matrix disruption, and preventing apoptosis. |
2008-11-04 |
2023-08-12 |
Not clear |
| Michelle J Nyhan, Gerald C O'Sullivan, Sharon L McKenn. Role of the VHL (von Hippel-Lindau) gene in renal cancer: a multifunctional tumour suppressor. Biochemical Society transactions. vol 36. issue Pt 3. 2008-11-03. PMID:18481984. |
additional functions of pvhl that may be important in preventing ccrcc tumorigenesis have been identified, including primary cilium maintenance, assembly of the extracellular matrix and roles in the stabilization of p53 and jade-1 (gene for apoptosis and differentiation in epithelia). |
2008-11-03 |
2023-08-12 |
Not clear |
| Amy M Boddy, Guy M Lenk, John H Lillvis, Jennifer Nischan, Yoshiki Kyo, Helena Kuivaniem. Basic research studies to understand aneurysm disease. Drug news & perspectives. vol 21. issue 3. 2008-11-03. PMID:18560612. |
critical pathways involved in aaa pathogenesis include immunological processes, such as t-cell and natural killer cell pathways, oxidative stress, depletion of vascular smooth muscle cells through the process of apoptosis and the destruction of the extracellular matrix by matrix metalloproteinases. |
2008-11-03 |
2023-08-12 |
Not clear |
| David A Tuli. Rat carotid artery balloon injury model. Methods in molecular medicine. vol 139. 2008-10-27. PMID:18287662. |
this elicits a reproducible remodeling response characterized by vascular smooth muscle cell (smc) mitogenesis and migration (through phenotypic switching), smc apoptosis, partial vascular endothelial cell regeneration, enhanced matrix synthesis, and establishment of an invasive neointima in time-dependent fashion. |
2008-10-27 |
2023-08-12 |
human |
| David A Tuli. Histological and morphometric analyses for rat carotid balloon injury model. Methods in molecular medicine. vol 139. 2008-10-27. PMID:18287663. |
the adaptive response to this injury is typified by robust vascular smooth muscle cell (smc) replication and migration, smc apoptosis and necrosis, enhanced synthesis and deposition of extracellular matrix (ecm) components, partial vascular ec regeneration from the border zones, luminal narrowing, and establishment of a neointima in time-dependent fashion. |
2008-10-27 |
2023-08-12 |
rat |
| Q Zhong, Y-J Wen, H-S Yang, H Luo, A-F Fu, F Yang, L-J Chen, X Chen, X-R Qi, H-G Lin, Y Wan, X-C Chen, Y-Q Wei, X Zha. Efficient inhibition of cisplatin-resistant human ovarian cancer growth and prolonged survival by gene transferred vesicular stomatitis virus matrix protein in nude mice. Annals of oncology : official journal of the European Society for Medical Oncology. vol 19. issue 9. 2008-10-27. PMID:18436522. |
the vesicular stomatitis virus matrix protein (vsvmp) has been receiving attention as an anticancer agent because of its ability of inducing apoptosis. |
2008-10-27 |
2023-08-12 |
mouse |
| Yi-Ling Huang, Chun-Yu Chuang, Fung-Chang Sung, Chia-Yang Che. Thioredoxin overexpression modulates remodeling factors in stress responses to cigarette smoke. Journal of toxicology and environmental health. Part A. vol 71. issue 22. 2008-10-21. PMID:18836924. |
results showed that cs stimulated ros generation and apoptosis in normal human bronchial epithelial (beas-2b) cells, and interfered with gene expression of remodeling factors, such as activation of transforming growth factor (tgf)-beta1, epidermal growth factor receptor (egfr), and cyclin-dependent kinase inhibitor (p21), but repressed matrix metalloproteinases (mmp)-9. |
2008-10-21 |
2023-08-12 |
human |
| Wen-Jun Wu, Chin-Feng Lee, Chung-Han Hsin, Jyun-Yi Du, Tsai-Ching Hsu, Ting-Hui Lin, Tsung-You Yao, Cheng-Hsieh Huang, Yi-Ju Le. TGF-beta inhibits prolactin-induced expression of beta-casein by a Smad3-dependent mechanism. Journal of cellular biochemistry. vol 104. issue 5. 2008-10-17. PMID:18335503. |
transforming growth factor-beta (tgf-beta) is a multifunctional growth factor, affecting cell proliferation, apoptosis, and extracellular matrix homeostasis. |
2008-10-17 |
2023-08-12 |
mouse |
| Alix Gazel, Martin Rosdy, Carine Tornier, Anne De Brugerolle De Fraissinette, Miroslav Blumenber. Transcriptional profiling defines the effects of nickel in human epidermal keratinocytes. Journal of cellular physiology. vol 217. issue 3. 2008-10-16. PMID:18651567. |
functional categories of regulated genes suggest that ni inhibits apoptosis, promotes cell cycle and induces synthesis of extracellular matrix proteins and extracellular proteases. |
2008-10-16 |
2023-08-12 |
human |
| Vijay Alla, Anubha Kashyap, Sebastian Gregor, Matthias Theobald, Hans Heid, Peter R Galle, Dennis Strand, Susanne Stran. Human leukocyte elastase counteracts matrix metalloproteinase-7 induced apoptosis resistance of tumor cells. Cancer letters. vol 268. issue 2. 2008-10-14. PMID:18485588. |
human leukocyte elastase counteracts matrix metalloproteinase-7 induced apoptosis resistance of tumor cells. |
2008-10-14 |
2023-08-12 |
human |