| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wenjun Wang, Jianshuang Li, Qinghua Zho. The biological function of cytoplasm-translocated ENDOG (endonuclease G). Autophagy. 2023-10-27. PMID:37889084. |
collectively, endog will be released from the mitochondrial intermembrane space, and translocated to the mitochondrial matrix, cytoplasm, and nucleus during different stress stimulation, where it digests dna or interacts with crucial proteins to regulate different biological functions, including apoptosis, autophagy, mitophagy, and lipid synthesis. |
2023-10-27 |
2023-11-08 |
Not clear |
| Albert Armoo, Tanner Diemer, Abigail Donkor, Jerrod Fedorchik, Severine Van Slambrouck, Rachel Willand-Charnley, Brian A Logu. Methimazole, an Effective Neutralizing Agent of the Sulfur Mustard Derivative 2-Chloroethyl Ethyl Sulfide. ACS bio & med chem Au. vol 3. issue 5. 2023-10-26. PMID:37876493. |
cell viability, relative loss of extracellular matrix adhesions, and apoptosis caused by cees were measured via mtt, cell-matrix adhesion (cma), and apoptosis protein marker assays, respectively. |
2023-10-26 |
2023-11-08 |
human |
| Xin Jin, Hainan Xu, Qing Hu, Yitong Yin, Meiying Qin, Zhijun Xi. Early growth response 2, a novel target of pelvic organ prolapse, is highly expressed in anterior vaginal wall tissues with pelvic organ prolapse. Histochemistry and cell biology. 2023-10-24. PMID:37874337. |
overall, our study illustrated that egr2 was highly expressed in pop tissues, and knockdown of egr2 alleviated apoptosis and reduced matrix degradation in pop fibroblasts. |
2023-10-24 |
2023-11-08 |
Not clear |
| Nan Meng, Lingwei Mao, Qinyi Jiang, Jishan Yuan, Linjuan Liu, Lei Wan. PLXNC1 interference alleviates the inflammatory injury, apoptosis and extracellular matrix degradation of IL-1β-exposed chondrocytes via suppressing GRP78 expression. Journal of orthopaedic surgery and research. vol 18. issue 1. 2023-10-20. PMID:37853395. |
plxnc1 interference alleviates the inflammatory injury, apoptosis and extracellular matrix degradation of il-1β-exposed chondrocytes via suppressing grp78 expression. |
2023-10-20 |
2023-11-08 |
human |
| Yanhui Ge, Zhan Wang, Xuelu Chen, Wen Wang, Zhenying Liu, Hongwen Sun, Lianying Zhan. Comparative Toxicological Effects of PFOS and its Alternative 6:2 Chlorinated Polyfluorinated Ether Sulfonate on Earthworms. Environmental toxicology and chemistry. 2023-10-20. PMID:37861387. |
compared to pfos, f-53b exhibited a weaker disruption of lipid metabolism, comparable potency for toxicity to the immune response, and a stronger potency in the extracellular matrix (ecm) destruction along with apoptosis and ferroptosis induction. |
2023-10-20 |
2023-11-08 |
cat |
| Dong Zheng, Kaiyuan Yang, Tong Chen, Songwei Lv, Liangliang Wang, Jianchao Gui, Chao X. Inhibition of LncRNA SNHG14 protects chondrocyte from injury in osteoarthritis via sponging miR-137. Autoimmunity. vol 56. issue 1. 2023-10-18. PMID:37849308. |
to measure the expression of the lncrnas snhg14 and mir-137, cell survival, inflammatory response, chondrocyte apoptosis, and extracellular matrix (ecm) levels, we subjected human chondrocytes to a variety of lipopolysaccharide (lps) concentrations. |
2023-10-18 |
2023-11-08 |
human |
| Dong Zheng, Kaiyuan Yang, Tong Chen, Songwei Lv, Liangliang Wang, Jianchao Gui, Chao X. Inhibition of LncRNA SNHG14 protects chondrocyte from injury in osteoarthritis via sponging miR-137. Autoimmunity. vol 56. issue 1. 2023-10-18. PMID:37849308. |
the results showed that chondrocyte viability was significantly inhibited with lps treatment and chondrocyte inflammatory response, apoptosis and extracellular matrix degradation were significantly increased. |
2023-10-18 |
2023-11-08 |
human |
| Dong Zheng, Kaiyuan Yang, Tong Chen, Songwei Lv, Liangliang Wang, Jianchao Gui, Chao X. Inhibition of LncRNA SNHG14 protects chondrocyte from injury in osteoarthritis via sponging miR-137. Autoimmunity. vol 56. issue 1. 2023-10-18. PMID:37849308. |
in conclusion, inhibition of lncrna snhg14 attenuates chondrocyte inflammatory response, apoptosis and extracellular matrix degradation by targeting mir-137 in lps induced chondrocytes. |
2023-10-18 |
2023-11-08 |
human |
| Saeedeh Keyvani-Ghamsari, Maryam Rahimi, Khatereh Khorsand. An update on the potential mechanism of gallic acid as an antibacterial and anticancer agent. Food science & nutrition. vol 11. issue 10. 2023-10-12. PMID:37823155. |
also, ga inhibits cancer cell growth by targeting different signaling pathways in apoptosis, increasing reactive oxygen species (ros) production, targeting the cell cycle, and inhibiting oncogenes and matrix metalloproteinases (mmps) expression. |
2023-10-12 |
2023-10-15 |
Not clear |
| Yan Liu, Yi-Hui Shao, Jun-Meng Zhang, Ying Wang, Mei Zhou, Hui-Qin Li, Cong-Cong Zhang, Pei-Jie Yu, Shi-Juan Gao, Xue-Rui Wang, Li-Xin Jia, Chun-Mei Piao, Jie Du, Yu-Lin L. Macrophage CARD9 mediates cardiac injury following myocardial infarction through regulation of lipocalin 2 expression. Signal transduction and targeted therapy. vol 8. issue 1. 2023-10-12. PMID:37828006. |
additionally, card9 ko suppressed cardiomyocyte apoptosis in the border region and attenuated matrix metalloproteinase (mmp) expression. |
2023-10-12 |
2023-10-15 |
mouse |
| Yuan Gao, Qinghua Huang, Yuling Qin, Xianhui Bao, You Pan, Jianlan Mo, Shipeng Nin. A prognostic model related to necrotizing apoptosis of breast cancer based on biorthogonal constrained depth semi-supervised nonnegative matrix decomposition and single-cell sequencing analysis. American journal of cancer research. vol 13. issue 9. 2023-10-11. PMID:37818066. |
a prognostic model related to necrotizing apoptosis of breast cancer based on biorthogonal constrained depth semi-supervised nonnegative matrix decomposition and single-cell sequencing analysis. |
2023-10-11 |
2023-10-15 |
Not clear |
| Hao-Wei Xu, Xin-Yue Fang, Xiao-Wei Liu, Shu-Bao Zhang, Yu-Yang Yi, Sheng-Jie Chang, Hao Chen, Shan-Jin Wan. α-Ketoglutaric acid ameliorates intervertebral disk degeneration by blocking the IL-6/JAK2/STAT3 pathway. American journal of physiology. Cell physiology. vol 325. issue 4. 2023-10-10. PMID:37661920. |
α-kg supplementation significantly attenuated senescence, apoptosis, and matrix metalloproteinase-13 (mmp-13) protein expression, and it increased the synthesis of aggrecan and collagen ii in il-1β-treated npcs. |
2023-10-10 |
2023-10-15 |
rat |
| Hongtao Li, Hongyu Pan, Changming Xiao, Hanyue Li, Longhai Long, Xiaoqiang Wang, Shengyu Luo, Kexin Lyu, Yixuan Chen, Li Jiang, Jingwei Lu, Huarui Shen, Sen L. IL-1β-mediated inflammatory responses in intervertebral disc degeneration: Mechanisms, signaling pathways, and therapeutic potential. Heliyon. vol 9. issue 9. 2023-10-09. PMID:37809657. |
current studies have found that il-1β is mainly involved in idd by affecting the metabolism of the extracellular matrix and regulating cell death (rcd), such as apoptosis, pyroptosis, and ferroptosis (a new form of rcd). |
2023-10-09 |
2023-10-15 |
Not clear |
| Wen Li, Xing-Hua Li, Yang Gao, Cheng-Jie Xiong, Zhong-Zhi Tan. Emerging roles of RNA binding proteins in intervertebral disc degeneration and osteoarthritis. Orthopaedic surgery. 2023-10-07. PMID:37803912. |
dysregulated phenotypes of nucleus pulposus (np) cells and oa chondrocytes, including apoptosis, extracellular matrix disruption, inflammation, and angiogenesis, are involved at all developmental stages of idd and oa. |
2023-10-07 |
2023-10-15 |
Not clear |
| Georgia Atkinson, Rosaria Bianco, Karina Di Gregoli, Jason L Johnso. The contribution of matrix metalloproteinases and their inhibitors to the development, progression, and rupture of abdominal aortic aneurysms. Frontiers in cardiovascular medicine. vol 10. 2023-10-06. PMID:37799778. |
matrix metalloproteinases (mmps) and their regulation by tissue inhibitors metalloproteinases (timps) can orchestrate not only ecm remodelling, but also moderate the proliferation, migration, and apoptosis of resident aortic cells, alongside the recruitment and subsequent behaviour of inflammatory cells. |
2023-10-06 |
2023-10-07 |
human |
| Wen-Peng Xie, Teng Ma, Yan-Chen Liang, Xiang-Peng Wang, Rong-Xiu Bi, Wei-Guo Wang, Yong-Kui Zhan. [Cangxi Tongbi Capsules promote chondrocyte autophagy by regulating circRNA＿0008365/miR-1271/p38 MAPK pathway to inhibit development of knee osteoarthritis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 18. 2023-10-06. PMID:37802826. |
the chondrocytes treated with il-1β showed down-regulated expression of circrna＿0008365, up-regulated expression of mir-1271 and p38 mapk, lowered autophagy level, increased apoptosis rate, and accelerated catabolism of extracellular matrix. |
2023-10-06 |
2023-10-15 |
rat |
| Wen-Peng Xie, Teng Ma, Yan-Chen Liang, Xiang-Peng Wang, Rong-Xiu Bi, Wei-Guo Wang, Yong-Kui Zhan. [Cangxi Tongbi Capsules promote chondrocyte autophagy by regulating circRNA＿0008365/miR-1271/p38 MAPK pathway to inhibit development of knee osteoarthritis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 18. 2023-10-06. PMID:37802826. |
the intervention with cangxi tongbi capsules up-regulated the expression of circrna＿0008365, down-regulated the expression of mir-1271 and p38 mapk, increased the autophagy level, decreased the apoptosis rate, and weakened the catabolism of extracellular matrix. |
2023-10-06 |
2023-10-15 |
rat |
| Yunfei Qu, Ning Zhang, Yu Zha. Resveratrol Inhibits Abdominal Aortic Aneurysm Progression by Reducing Extracellular Matrix Degradation, Apoptosis, Autophagy, and Inflammation of Vascular Smooth Muscle Cells via Upregulation of HMOX1. Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists. 2023-10-04. PMID:37789605. |
resveratrol inhibits abdominal aortic aneurysm progression by reducing extracellular matrix degradation, apoptosis, autophagy, and inflammation of vascular smooth muscle cells via upregulation of hmox1. |
2023-10-04 |
2023-10-07 |
Not clear |
| Huan Deng, Xuedong Shu, Yao Wang, Junwei Zhang, Yue Yin, Fang Wu, Jing H. Matrix Stiffness Regulated Endoplasmic Reticulum Stress-mediated Apoptosis of Osteosarcoma Cell through Ras Signal Cascades. Cell biochemistry and biophysics. 2023-10-03. PMID:37789235. |
matrix stiffness regulated endoplasmic reticulum stress-mediated apoptosis of osteosarcoma cell through ras signal cascades. |
2023-10-03 |
2023-10-07 |
Not clear |
| Huan Deng, Xuedong Shu, Yao Wang, Junwei Zhang, Yue Yin, Fang Wu, Jing H. Matrix Stiffness Regulated Endoplasmic Reticulum Stress-mediated Apoptosis of Osteosarcoma Cell through Ras Signal Cascades. Cell biochemistry and biophysics. 2023-10-03. PMID:37789235. |
the modulating effects of matrix stiffness on spreading and apoptosis of tumor cells have been well recognized. |
2023-10-03 |
2023-10-07 |
Not clear |