| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yingjie Li, Cankun Wang, Anjun Ma, Abdul Qawee Rani, Mingjue Luo, Jenny Li, Xuefeng Liu, Qin M. Identification of HPV oncogene and host cell differentiation associated cellular heterogeneity in cervical cancer via single-cell transcriptomic analysis. bioRxiv : the preprint server for biology. 2023-08-30. PMID:37645794. |
these hpv-positive cells, compared to hpv-negative, showed different gene expressions related to the extracellular matrix, cell adhesion, proliferation, and apoptosis. |
2023-08-30 |
2023-09-07 |
human |
| Kanna Xu, Haoran Wang, Zhongqing W. Genkwanin suppresses mitochondrial dysfunction to alleviate IL-1β-elicited inflammation, apoptosis, and degradation of extracellular matrix in chondrocytes through upregulating DUSP1. The Chinese journal of physiology. vol 66. issue 4. 2023-08-28. PMID:37635488. |
genkwanin suppresses mitochondrial dysfunction to alleviate il-1β-elicited inflammation, apoptosis, and degradation of extracellular matrix in chondrocytes through upregulating dusp1. |
2023-08-28 |
2023-09-07 |
Not clear |
| Yuelong Zhang, Huangming Zhuang, Xunshan Ren, Fuze Jiang, Panghu Zho. Therapeutic effects of different intervention forms of human umbilical cord mesenchymal stem cells in the treatment of osteoarthritis. Frontiers in cell and developmental biology. vol 11. 2023-08-28. PMID:37635870. |
huc-mscs secret extracellular vesicles and participates in oa treatment by transmitting bioactive molecules related to migration, proliferation, apoptosis, inflammatory reaction, extracellular matrix synthesis and cartilage repair. |
2023-08-28 |
2023-09-07 |
human |
| Yingjie Li, Cankun Wang, Anjun Ma, Abdul Qawee Rani, Mingjue Luo, Jenny Li, Xuefeng Liu, Qin M. Identification of HPV oncogene and host cell differentiation associated cellular heterogeneity in cervical cancer via single-cell transcriptomic analysis. Journal of medical virology. vol 95. issue 8. 2023-08-28. PMID:37638381. |
these hpv-positive cells, compared to hpv-negative, showed different gene expressions related to the extracellular matrix, cell adhesion, proliferation, and apoptosis. |
2023-08-28 |
2023-09-07 |
human |
| Fan Zhang, Liang Liu, Hui Wang, Liaobin Che. Effects of prenatal acetaminophen exposure at different stages, doses and courses on articular cartilage of offspring mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023-08-26. PMID:37633638. |
fetal knee joints were harvested on gd18 to analyze cartilage morphology, chondrocyte proliferation and apoptosis, and matrix content, synthesis and degradation. |
2023-08-26 |
2023-09-07 |
mouse |
| Fan Zhang, Liang Liu, Hui Wang, Liaobin Che. Effects of prenatal acetaminophen exposure at different stages, doses and courses on articular cartilage of offspring mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023-08-26. PMID:37633638. |
results showed that 400 mg/kg∙d acetaminophen exposure during gd10-12 decreased chondrocyte numbers, safranin o staining, proliferation and matrix synthesis, without elevating matrix degradation and apoptosis. |
2023-08-26 |
2023-09-07 |
mouse |
| Liyun Zhang, Wei Li, Xin Liu, Junhong Guo, Xueping Wu, Jiantao Wan. Niclosamide inhibits TGF-β1-induced fibrosis of human Tenon's fibroblasts by regulating the MAPK-ERK1/2 pathway. Experimental eye research. 2023-08-24. PMID:37619828. |
niclosamide also induced apoptosis and counteracted tgf-β1-induced cytoskeletal changes and extracellular matrix accumulation. |
2023-08-24 |
2023-09-07 |
human |
| Tianyou Kan, Zhaoyang Ran, Lin Sun, Xu Jiang, Lingli Hou, Yiqi Yang, Zhuoxuan Jia, Wenjie Zhang, Liao Wang, Mengning Yan, Kai Xi. Cell-free fat extract-loaded microneedles attenuate inflammation-induced apoptosis and mitochondrial damage in tendinopathy. Materials today. Bio. vol 22. 2023-08-21. PMID:37600349. |
we found that ceffe-loaded mns (ceffe-mns) had good biosafety and inhibited lipopolysaccharide (lps)-induced apoptosis and matrix degradation in achilles tendon cells of rats. |
2023-08-21 |
2023-09-07 |
rat |
| Jiaqi Chen, Jianan Shao, Yaoyao Wang, Kangxiang Wu, Mingyuan Huan. OPA1, a molecular regulator of dilated cardiomyopathy. Journal of cellular and molecular medicine. 2023-08-21. PMID:37603376. |
opa1 regulates apoptosis by regulating the release of cytochrome c from the mitochondrial matrix through cjs (crisp linkages, located in the inner mitochondrial membrane) and unbalances mitochondrial fusion and fission by affecting mitochondrial inner membrane (im) fusion. |
2023-08-21 |
2023-09-07 |
Not clear |
| Lu Zhang, Junsheng Gao, Zhentao Li, Jun Liu, Chong Zhang, Jie Liu, Hui Dong, Wei Me. Astragaloside IV relieves IL-1β-induced human nucleus pulposus cells degeneration through modulating PI3K/Akt signaling pathway. Medicine. vol 102. issue 33. 2023-08-21. PMID:37603510. |
intervertebral disc degeneration (idd) is a multifactorial disease that is associated with nucleus pulposus (np) apoptosis and extracellular matrix (ecm) degeneration and inflammation. |
2023-08-21 |
2023-09-07 |
human |
| Jin Xu, Xiaocheng Zhi, Yunhui Zhang, Ren Din. Tanshinone IIA alleviates chondrocyte apoptosis and extracellular matrix degeneration by inhibiting ferroptosis. Open life sciences. vol 18. issue 1. 2023-08-17. PMID:37589005. |
tanshinone iia alleviates chondrocyte apoptosis and extracellular matrix degeneration by inhibiting ferroptosis. |
2023-08-17 |
2023-09-07 |
Not clear |
| Lian Ren, Shi-Gao Cheng, Peng-Cheng Kang, Teng-Fei Li, Xun Li, Jiong-Zhe Xiao, Dong Jian. Silenced LASP1 interacts with DNMT1 to promote TJP2 expression and attenuate articular cartilage injury in mice by suppressing TJP2 methylation. The Kaohsiung journal of medical sciences. 2023-08-14. PMID:37578083. |
silencing of lasp1 promoted chondrocyte proliferation and expression of collagen ii and aggrecan and inhibited chondrocyte apoptosis, inflammatory factors, and matrix metalloprotein expression. |
2023-08-14 |
2023-08-16 |
mouse |
| Yan Chen, Xiankun Cao, Bin Pan, Han Du, Baixing Li, Xiao Yang, Xuzhuo Chen, Xin Wang, Tangjun Zhou, An Qin, Changqing Zhao, Jie Zha. Verapamil attenuates intervertebral disc degeneration by suppressing ROS overproduction and pyroptosis via targeting the Nrf2/TXNIP/NLRP3 axis in four-week puncture-induced rat models both in vivo and in vitro. International immunopharmacology. vol 123. 2023-08-14. PMID:37579541. |
administration of verapamil, a classic clinical drug, mitigated the tbhp-induced overproduction of reactive oxygen species and activation of the nlrp3 inflammasome, thus protecting cells from pyroptosis, apoptosis, and extracellular matrix degradation. |
2023-08-14 |
2023-09-07 |
rat |
| Zhaowei Lin, Tao Jiang, Wei Zheng, Jiayuan Zhang, Anan Li, Chao Lu, Wengang Li. N6-methyladenosine (m6A) methyltransferase WTAP-mediated miR-92b-5p accelerates osteoarthritis progression. Cell communication and signaling : CCS. vol 21. issue 1. 2023-08-10. PMID:37563688. |
functional studies have demonstrated that wtap knockdown enhances proliferation ability, suppresses apoptosis, and reduces extracellular matrix (ecm) degradation in an lps-induced oa chondrocyte injury model and ameliorates cartilage damage in a destabilizing the medial meniscus (dmm)-induced oa mice model. |
2023-08-10 |
2023-08-16 |
mouse |
| Aika Yamawaki-Ogata, Masato Mutsuga, Yuji Narit. A review of current status of cell-based therapies for aortic aneurysms. Inflammation and regeneration. vol 43. issue 1. 2023-08-06. PMID:37544997. |
the aneurysmal wall is a complex inflammatory environment characterized by endothelial dysfunction, macrophage activation, vascular smooth muscle cell (vsmc) apoptosis, and the production of proinflammatory molecules and matrix metalloproteases (mmps) secreted by infiltrated inflammatory cells such as macrophages, t and b cells, dendritic cells, neutrophils, mast cells, and natural killer cells. |
2023-08-06 |
2023-08-14 |
Not clear |
| Takahiro Suzuki, Fernanda Scala Dinelli, Dana-Lee Demetrius, Jennifer Gherardini, Jose Rodriguez-Feliz, Gorana Epstein-Kuka, Jérémy Chéret, Ralf Pau. IL-15 prolongs anagen, stimulates proliferation and suppresses apoptosis in the hair matrix of human scalp hair follicles. The Journal of investigative dermatology. 2023-08-05. PMID:37543243. |
il-15 prolongs anagen, stimulates proliferation and suppresses apoptosis in the hair matrix of human scalp hair follicles. |
2023-08-05 |
2023-08-14 |
human |
| Shanbo Qin, Peng Tan, Junjie Xie, Yongfeng Zhou, Junning Zha. A systematic review of the research progress of traditional Chinese medicine against pulmonary fibrosis: from a pharmacological perspective. Chinese medicine. vol 18. issue 1. 2023-08-03. PMID:37537605. |
the anti-fibrotic mechanisms of these traditional chinese medicine studies can be roughly categorized into 5 main aspects, including inhibition of epithelial-mesenchymal transition, anti-inflammatory and antioxidant effects, improvement of extracellular matrix deposition, mediation of apoptosis and autophagy, and inhibition of endoplasmic reticulum stress. |
2023-08-03 |
2023-08-14 |
human |
| Kadirvel Devi, Thukani Sathanantham Shanmugaraja. Therapeutic Potential of Plant Metabolites in Bone Apoptosis: A Review. Current drug targets. 2023-08-01. PMID:37526458. |
osteoblast apoptosis is governed by the factors like b cell lymphoma 2 (bcl-2) family proteins, extracellular signal-regulated kinase (erk), mitogen-activated protein kinases (mapk), phosphoinositide-3-kinase/ protein kinase b (pi3-k/akt), janus kinase 2 (jak2), bone morphogenetic protein (bmp), and bone matrix protein. |
2023-08-01 |
2023-08-14 |
Not clear |
| Francesca Veronesi, Viviana Costa, Daniele Bellavia, Valentina Basoli, Gianluca Giavares. Epigenetic Modifications of MiRNAs in Osteoarthritis: A Systematic Review on Their Methylation Levels and Effects on Chondrocytes, Extracellular Matrix and Joint Inflammation. Cells. vol 12. issue 14. 2023-07-29. PMID:37508486. |
osteoarthritis (oa) is a joint disorder characterized by progressive degeneration of cartilage extracellular matrix (ecm), chondrocyte hypertrophy and apoptosis and inflammation. |
2023-07-29 |
2023-08-14 |
Not clear |
| Liujie Zheng, Yunfeng Yao, Dasheng Luo, Zhiwei Han, Xin Zhang, Nanyu Pang, Mingyang Ding, Houlong Ye, Keyan Zhu, Wenkai Y. Iron regulates chondrocyte phenotype in haemophilic cartilage through the PTEN/PI3 K/AKT/FOXO1 pathway. Hematology (Amsterdam, Netherlands). vol 28. issue 1. 2023-07-26. PMID:37493406. |
this change was caused by iron's effect on chondrocyte expression of fgf23 and sox9, in addition to iron-induced chondrocyte apoptosis and cartilage extracellular matrix degradation. |
2023-07-26 |
2023-08-14 |
Not clear |