| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qing-Guo Xu, Ling Jiang, Jun Hou, Shu-Jun Wang, Chun Chen, Xiang H. [Effect of electroacupuncture on cognitive functions, hippocampal HIF-1α and neurons apoptosis in postoperative cognitive dysfunction rats]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 40. issue 3. 2020-07-22. PMID:32270642. |
to observe the effect of electroacupuncture (ea) on learning and memory ability, hippocampal hypoxia inducible factor-1α(hif-1α) and apoptosis in postoperative cognitive dysfunction(pocd) rats, and to investigate its mechanism underlying improvement of pocd. |
2020-07-22 |
2023-08-13 |
rat |
| Ki Yun Kim, Su-Kyeong Hwang, Shin Young Park, Min Ju Kim, Do Youn Jun, Young Ho Ki. l-Serine protects mouse hippocampal neuronal HT22 cells against oxidative stress-mediated mitochondrial damage and apoptotic cell death. Free radical biology & medicine. vol 141. 2020-07-21. PMID:31326607. |
the cytoprotective mechanism of l-serine against oxidative stress-mediated neuronal apoptosis was investigated in mouse hippocampal neuronal ht22 cells. |
2020-07-21 |
2023-08-13 |
mouse |
| Yu-Qing Li, Marianne Koritzinsky, C Shun Won. Metabolic Regulation of Hippocampal Neuroprogenitor Apoptosis After Irradiation. Journal of neuropathology and experimental neurology. vol 79. issue 3. 2020-07-21. PMID:31738417. |
metabolic regulation of hippocampal neuroprogenitor apoptosis after irradiation. |
2020-07-21 |
2023-08-13 |
mouse |
| Yu-Qing Li, Marianne Koritzinsky, C Shun Won. Metabolic Regulation of Hippocampal Neuroprogenitor Apoptosis After Irradiation. Journal of neuropathology and experimental neurology. vol 79. issue 3. 2020-07-21. PMID:31738417. |
in this study, we asked if 5'-adenosine monophosphate-activated protein kinase (ampk), the master sensor of cellular energy balance, played a role in p53-dependent apoptosis of neural progenitor cells (npcs) in the hippocampus after irradiation. |
2020-07-21 |
2023-08-13 |
mouse |
| Yu-Qing Li, Marianne Koritzinsky, C Shun Won. Metabolic Regulation of Hippocampal Neuroprogenitor Apoptosis After Irradiation. Journal of neuropathology and experimental neurology. vol 79. issue 3. 2020-07-21. PMID:31738417. |
adult mice with targeted disruption of p53 or prkaa2 (gene that encodes ampkα) in the brain were used to determine the role of p53 and ampk, respectively, in radiation-induced apoptosis of npcs in the hippocampus. |
2020-07-21 |
2023-08-13 |
mouse |
| Yu-Qing Li, Marianne Koritzinsky, C Shun Won. Metabolic Regulation of Hippocampal Neuroprogenitor Apoptosis After Irradiation. Journal of neuropathology and experimental neurology. vol 79. issue 3. 2020-07-21. PMID:31738417. |
we conclude that ampk may regulate apoptosis of hippocampal npcs after irradiation. |
2020-07-21 |
2023-08-13 |
mouse |
| Fatemeh Mohammadian, Maryam Arab Firouzjaei, Masoud Haghani, Mohammad Shabani, Seyed Mostafa Shid Moosavi, Fatemeh Mohammad. Inhibition of inflammation is not enough for recovery of cognitive impairment in hepatic encephalopathy: Effects of minocycline and ibuprofen. Brain research bulletin. vol 149. 2020-07-20. PMID:31005662. |
the bdl increased hippocampal apoptosis and bbb disruption, which were fully recovered by all three pharmacological interventions. |
2020-07-20 |
2023-08-13 |
rat |
| Yin Cao, Qinglin Li, Lulu Liu, Hui Wu, Fei Huang, Changhong Wang, Yunyi Lan, Fang Zheng, Faping Xing, Qiang Zhou, Qi Li, Hailian Shi, Beibei Zhang, Zhengtao Wang, Xiaojun W. Modafinil protects hippocampal neurons by suppressing excessive autophagy and apoptosis in mice with sleep deprivation. British journal of pharmacology. vol 176. issue 9. 2020-07-15. PMID:30767208. |
modafinil protects hippocampal neurons by suppressing excessive autophagy and apoptosis in mice with sleep deprivation. |
2020-07-15 |
2023-08-13 |
mouse |
| Minmin Yao, Zhimeng Zhao, Lan Wei, Di Zhou, Zhanggang Xue, Shengjin G. HSF1/HSP pathway in the hippocampus is involved in SIRT1-mediated caloric restriction-induced neuroprotection after surgery in aged mice. Experimental gerontology. vol 119. 2020-07-15. PMID:30772489. |
cr alleviated er-stress and neuronal apoptosis in the hippocampus induced by surgery. |
2020-07-15 |
2023-08-13 |
mouse |
| Xiaoyi Pang, Peigen Zhang, Yang Zhou, Jing Zhao, Hong Li. Dexmedetomidine pretreatment attenuates isoflurane-induced neurotoxicity via inhibiting the TLR2/NF-κB signaling pathway in neonatal rats. Experimental and molecular pathology. vol 112. 2020-07-15. PMID:31678237. |
ultrastructure of hippocampal neurons, neuronal apoptosis, and the levels of tlr2/nf-κb signaling pathway-related factors were determined. |
2020-07-15 |
2023-08-13 |
rat |
| Titikorn Chunchai, Puntarik Keawtep, Apiwan Arinno, Napatsorn Saiyasit, Dillon Prus, Nattayaporn Apaijai, Wasana Pratchayasakul, Nipon Chattipakorn, Siriporn C Chattipakor. N-acetyl cysteine, inulin and the two as a combined therapy ameliorate cognitive decline in testosterone-deprived rats. Aging. vol 11. issue 11. 2020-07-13. PMID:31160542. |
orx rats also demonstrated glia hyperactivation, resulting in hippocampal apoptosis, hippocampal dysplasticity, and cognitive decline. |
2020-07-13 |
2023-08-13 |
rat |
| Titikorn Chunchai, Puntarik Keawtep, Apiwan Arinno, Napatsorn Saiyasit, Dillon Prus, Nattayaporn Apaijai, Wasana Pratchayasakul, Nipon Chattipakorn, Siriporn C Chattipakor. N-acetyl cysteine, inulin and the two as a combined therapy ameliorate cognitive decline in testosterone-deprived rats. Aging. vol 11. issue 11. 2020-07-13. PMID:31160542. |
all treatments equally ameliorated cognitive decline by improving gut dysbiosis, alleviating bbb dysfunction, decreasing hippocampal ros production, decreasing hippocampal apoptosis, and reducing microglia and astrocyte activity. |
2020-07-13 |
2023-08-13 |
rat |
| Yahong Cheng, Qianting Mai, Xin Zeng, Huiling Wang, Yao Xiao, Liu Tang, Jing Li, Yiyuan Zhang, Hong Din. Propionate relieves pentylenetetrazol-induced seizures, consequent mitochondrial disruption, neuron necrosis and neurological deficits in mice. Biochemical pharmacology. vol 169. 2020-07-13. PMID:31491413. |
in conclusion, treatment with propionate attenuates mitochondrial disruption, hippocampal apoptosis and neurological deficits in a mouse model of epilepsy seizures. |
2020-07-13 |
2023-08-13 |
mouse |
| Rukmani Pandey, Pallavi Shukla, Baby Anjum, Himanshu Pawankumar Gupta, Subhashis Pal, Nidhi Arjaria, Keerti Gupta, Naibedya Chattopadhyay, Rohit A Sinha, Sanghamitra Bandyopadhya. Estrogen deficiency induces memory loss via altered hippocampal HB-EGF and autophagy. The Journal of endocrinology. vol 244. issue 1. 2020-07-13. PMID:31648182. |
estrogen deficiency reduces estrogen receptor-alpha (erα) and promotes apoptosis in the hippocampus, inducing learning-memory deficits; however, underlying mechanisms remain less understood. |
2020-07-13 |
2023-08-13 |
rat |
| Rukmani Pandey, Pallavi Shukla, Baby Anjum, Himanshu Pawankumar Gupta, Subhashis Pal, Nidhi Arjaria, Keerti Gupta, Naibedya Chattopadhyay, Rohit A Sinha, Sanghamitra Bandyopadhya. Estrogen deficiency induces memory loss via altered hippocampal HB-EGF and autophagy. The Journal of endocrinology. vol 244. issue 1. 2020-07-13. PMID:31648182. |
additionally, in vivo and in vitro studies suggested the participation of an attenuated hippocampal neuronal hb-egf and enhanced autophagy in apoptosis of hippocampal neurons in estrogen- and erα-deficient conditions. |
2020-07-13 |
2023-08-13 |
rat |
| Gaoyou Pei, Liguo Xu, Wenhao Huang, Jianjun Yi. The protective role of microRNA-133b in restricting hippocampal neurons apoptosis and inflammatory injury in rats with depression by suppressing CTGF. International immunopharmacology. vol 78. 2020-07-13. PMID:31830619. |
the protective role of microrna-133b in restricting hippocampal neurons apoptosis and inflammatory injury in rats with depression by suppressing ctgf. |
2020-07-13 |
2023-08-13 |
human |
| Xiaotong Wang, Xudan Liu, Yao Chen, Huanhuan Wang, Ruo Zhang, Qianhui Zhang, Yuting Wei, Sainan Shi, Xin L. Calreticulin regulated intrinsic apoptosis through mitochondria-dependent and independent pathways mediated by ER stress in arsenite exposed HT-22 cells. Chemosphere. vol 251. 2020-07-13. PMID:32443253. |
in this study, we found that crt expression as well as the cell apoptosis levels increased in a dose dependent manner upon arsenite exposure in ht-22 cells, a mouse hippocampal neural cell line. |
2020-07-13 |
2023-08-13 |
mouse |
| Lin-Juan Li, Jun-Chen Zheng, Rui Kang, Jian-Qun Ya. Targeting Trim69 alleviates high fat diet (HFD)-induced hippocampal injury in mice by inhibiting apoptosis and inflammation through ASK1 inactivation. Biochemical and biophysical research communications. vol 515. issue 4. 2020-07-06. PMID:31178136. |
targeting trim69 alleviates high fat diet (hfd)-induced hippocampal injury in mice by inhibiting apoptosis and inflammation through ask1 inactivation. |
2020-07-06 |
2023-08-13 |
mouse |
| Lin-Juan Li, Jun-Chen Zheng, Rui Kang, Jian-Qun Ya. Targeting Trim69 alleviates high fat diet (HFD)-induced hippocampal injury in mice by inhibiting apoptosis and inflammation through ASK1 inactivation. Biochemical and biophysical research communications. vol 515. issue 4. 2020-07-06. PMID:31178136. |
together, these results indicated that trim69 might be a functionally essential inhibitor of ask1 activation during the pathogenesis of hippocampal inflammation and apoptosis, and it could serve as a novel molecular target for obesity-associated brain damage. |
2020-07-06 |
2023-08-13 |
mouse |
| Bin Xu, Li-Min Lang, Shi-Ze Li, Jing-Ru Guo, Jian-Fa Wang, Huan-Min Yang, Shuai Lia. Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure. Biomolecules. vol 9. issue 9. 2020-07-06. PMID:31480279. |
cold stress can induce neuroinflammation in the hippocampal dentate gyrus (dg), but the mechanism underlying neuronal apoptosis induced by cold stress is not well-understood. |
2020-07-06 |
2023-08-13 |
mouse |