| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qin Sun, Qing-Cui Zeng, Yan-Qiu Chen, Min Zhang, Ling-Ling Wei, Ping Che. Long intergenic noncoding RNA p21 suppresses the apoptosis of hippocampus neurons in streptozotocin-diabetic mice by sponging microRNA-221 through upregulation of FOS. Journal of cellular physiology. vol 234. issue 11. 2020-06-01. PMID:31081202. |
overexpression of lincrna p21 promotes fos expression by binding to mir-221, thereby, inhibiting hippocampal neuron apoptosis in diabetic mice. |
2020-06-01 |
2023-08-13 |
mouse |
| Hua Fang, Hua-Feng Li, Miao Yang, Ren Liao, Ru-Rong Wang, Quan-Yun Wang, Peng-Cheng Zheng, Fang-Xiang Zhang, Jian-Ping Zhan. NF-κB signaling pathway inhibition suppresses hippocampal neuronal apoptosis and cognitive impairment via RCAN1 in neonatal rats with hypoxic-ischemic brain damage. Cell cycle (Georgetown, Tex.). vol 18. issue 9. 2020-05-27. PMID:30990350. |
nf-κb signaling pathway inhibition suppresses hippocampal neuronal apoptosis and cognitive impairment via rcan1 in neonatal rats with hypoxic-ischemic brain damage. |
2020-05-27 |
2023-08-13 |
rat |
| Hua Fang, Hua-Feng Li, Miao Yang, Ren Liao, Ru-Rong Wang, Quan-Yun Wang, Peng-Cheng Zheng, Fang-Xiang Zhang, Jian-Ping Zhan. NF-κB signaling pathway inhibition suppresses hippocampal neuronal apoptosis and cognitive impairment via RCAN1 in neonatal rats with hypoxic-ischemic brain damage. Cell cycle (Georgetown, Tex.). vol 18. issue 9. 2020-05-27. PMID:30990350. |
this study aimed to explore the mechanism of nf-κb signaling pathway in hippocampal neuron apoptosis and cognitive impairment of neonatal rats with hibd in relation to rcan1. |
2020-05-27 |
2023-08-13 |
rat |
| Zohreh Zare, Sam Zarbakhsh, Mohsen Tehrani, Moslem Mohammad. Paraoxon-induced damage in rat hippocampus is associated with alterations in the expression of apoptosis-related proteins. Pesticide biochemistry and physiology. vol 166. 2020-05-26. PMID:32448426. |
to determine the possible role of apoptosis in the development of paraoxon-induced brain damage, we evaluated expression of apoptosis-related proteins, the extent of neuronal damage, and activation of astrocytes in rat hippocampus. |
2020-05-26 |
2023-08-13 |
rat |
| Zohreh Zare, Sam Zarbakhsh, Mohsen Tehrani, Moslem Mohammad. Paraoxon-induced damage in rat hippocampus is associated with alterations in the expression of apoptosis-related proteins. Pesticide biochemistry and physiology. vol 166. 2020-05-26. PMID:32448426. |
our results indicated that neuronal damage induced by convulsive doses of paraoxon in rat hippocampus is mediated in part through apoptosis mechanism. |
2020-05-26 |
2023-08-13 |
rat |
| Donal T Skelly, Éadaoin W Griffin, Carol L Murray, Sarah Harney, Conor O'Boyle, Edel Hennessy, Marc-Andre Dansereau, Arshed Nazmi, Lucas Tortorelli, J Nicholas Rawlins, David M Bannerman, Colm Cunningha. Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms. Molecular psychiatry. vol 24. issue 10. 2020-05-21. PMID:29875474. |
direct application of il-1β to ex vivo hippocampal slices induced non-synaptic depolarisation and irreversible loss of membrane potential in ca1 neurons from diseased animals and systemic lps increased apoptosis in the degenerating brain, in an il-1ri-dependent fashion. |
2020-05-21 |
2023-08-13 |
mouse |
| Qingfa Chen, Hongling Ma, Xuewen Guo, Jia Liu, Ting Gui, Zhibo Ga. Farnesoid X Receptor (FXR) Aggravates Amyloid-β-Triggered Apoptosis by Modulating the cAMP-Response Element-Binding Protein (CREB)/Brain-Derived Neurotrophic Factor (BDNF) Pathway In Vitro. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-05-21. PMID:31812977. |
results we found that the mrna and protein expression of fxr was enhanced in ab-triggered neuronal apoptosis in differentiated sh-sy5y cells and in mouse hippocampal neurons. |
2020-05-21 |
2023-08-13 |
mouse |
| Guoyu Zhou, Sha Tang, Lu Yang, Qiang Niu, Jingwen Chen, Tao Xia, Sumei Wang, Mengwei Wang, Qian Zhao, Ling Liu, Pei Li, Lixin Dong, Kedi Yang, Shun Zhang, Aiguo Wan. Effects of long-term fluoride exposure on cognitive ability and the underlying mechanisms: Role of autophagy and its association with apoptosis. Toxicology and applied pharmacology. vol 378. 2020-05-20. PMID:31173788. |
using sprague-dawley rats exposed to sodium fluoride from 60 days before pregnancy until 6 months post-delivery as in vivo model, we showed that fluoride impaired the learning and memory abilities of offspring rats, with decreased neuronal number, suppressed autophagy and enhanced apoptosis in hippocampus. |
2020-05-20 |
2023-08-13 |
human |
| Susana Castelo Branco Ramos Nakandakari, Vitor Rosetto Muñoz, Gabriel Keine Kuga, Rafael Calais Gaspar, Marcella Ramos Sant'Ana, Isadora Carolina Betim Pavan, Luiz Guilherme Salvino da Silva, Ana Paula Morelli, Fernando Moreira Simabuco, Adelino Sanchez Ramos da Silva, Leandro Pereira de Moura, Eduardo Rochete Ropelle, Dennys Esper Cintra, José Rodrigo Paul. Short-term high-fat diet modulates several inflammatory, ER stress, and apoptosis markers in the hippocampus of young mice. Brain, behavior, and immunity. vol 79. 2020-05-13. PMID:30797044. |
short-term high-fat diet modulates several inflammatory, er stress, and apoptosis markers in the hippocampus of young mice. |
2020-05-13 |
2023-08-13 |
mouse |
| Zhao Jin, Peipei Guo, Xinyi Li, Jianjuan Ke, Yanlin Wang, Huisheng W. Neuroprotective effects of irisin against cerebral ischemia/ reperfusion injury via Notch signaling pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 120. 2020-05-13. PMID:31561067. |
the apoptosis of hippocampal neurons reduced in the presence of irisin in vivo and in vitro. |
2020-05-13 |
2023-08-13 |
mouse |
| Qian Zhao, Qiang Niu, Jingwen Chen, Tao Xia, Guoyu Zhou, Pei Li, Lixin Dong, Chunyan Xu, Zhiyuan Tian, Chen Luo, Luming Liu, Shun Zhang, Aiguo Wan. Roles of mitochondrial fission inhibition in developmental fluoride neurotoxicity: mechanisms of action in vitro and associations with cognition in rats and children. Archives of toxicology. vol 93. issue 3. 2020-05-12. PMID:30659323. |
consistently, using sprague-dawley rats developmentally exposed to naf (10, 50, and 100 mg/l) from pre-pregnancy until 2 months of delivery to mimic human exposure, we showed that perinatal exposure to environmentally relevant levels of fluoride caused learning and memory impairments, accompanied by hippocampal mitochondrial morphological alterations manifested as fission suppression and fusion acceleration, along with defective autophagy, excessive apoptosis and neuronal loss. |
2020-05-12 |
2023-08-13 |
human |
| Jin-Lu Yu, Chao Li, Li-He Che, Yu-Hao Zhao, Yun-Bao Gu. Downregulation of long noncoding RNA H19 rescues hippocampal neurons from apoptosis and oxidative stress by inhibiting IGF2 methylation in mice with streptozotocin-induced diabetes mellitus. Journal of cellular physiology. vol 234. issue 7. 2020-05-11. PMID:30536889. |
downregulation of long noncoding rna h19 rescues hippocampal neurons from apoptosis and oxidative stress by inhibiting igf2 methylation in mice with streptozotocin-induced diabetes mellitus. |
2020-05-11 |
2023-08-13 |
mouse |
| Jin-Lu Yu, Chao Li, Li-He Che, Yu-Hao Zhao, Yun-Bao Gu. Downregulation of long noncoding RNA H19 rescues hippocampal neurons from apoptosis and oxidative stress by inhibiting IGF2 methylation in mice with streptozotocin-induced diabetes mellitus. Journal of cellular physiology. vol 234. issue 7. 2020-05-11. PMID:30536889. |
the present study set out to define the critical role played by long noncoding rna h19 (lncrna h19) in the apoptosis of hippocampal neurons, as well as oxidative stress (os) in streptozotocin (stz)-induced dm mice through regulation of insulin-like growth factor 2 (igf2) methylation. |
2020-05-11 |
2023-08-13 |
mouse |
| Jin-Lu Yu, Chao Li, Li-He Che, Yu-Hao Zhao, Yun-Bao Gu. Downregulation of long noncoding RNA H19 rescues hippocampal neurons from apoptosis and oxidative stress by inhibiting IGF2 methylation in mice with streptozotocin-induced diabetes mellitus. Journal of cellular physiology. vol 234. issue 7. 2020-05-11. PMID:30536889. |
upregulated lncrna h19 significantly increased the expression of bax and caspase-3 but decreased that of bcl-2, thus promoting the apoptosis of hippocampal neuron. |
2020-05-11 |
2023-08-13 |
mouse |
| Jin-Lu Yu, Chao Li, Li-He Che, Yu-Hao Zhao, Yun-Bao Gu. Downregulation of long noncoding RNA H19 rescues hippocampal neurons from apoptosis and oxidative stress by inhibiting IGF2 methylation in mice with streptozotocin-induced diabetes mellitus. Journal of cellular physiology. vol 234. issue 7. 2020-05-11. PMID:30536889. |
taken together, downregulated lncrna h19 reduces igf2 methylation and enhances its expression, thereby suppressing hippocampal neuron apoptosis and os in stz-induced (dm) mice. |
2020-05-11 |
2023-08-13 |
mouse |
| Donal T Skelly, Éadaoin W Griffin, Carol L Murray, Sarah Harney, Conor O'Boyle, Edel Hennessy, Marc-Andre Dansereau, Arshed Nazmi, Lucas Tortorelli, J Nicholas Rawlins, David M Bannerman, Colm Cunningha. Correction: Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms. Molecular psychiatry. vol 24. issue 10. 2020-05-11. PMID:30890763. |
following publication of this article, the authors noticed an error in the abstract, where they incorrectly stated that: "direct application of il-1β to ex vivo hippocampal slices induced non-synaptic depolarisation and irreversible loss of membrane potential in ca1 neurons from diseased animals and systemic lps increased apoptosis in the degenerating brain, in an il-1ri-/--dependent fashion". |
2020-05-11 |
2023-08-13 |
Not clear |
| Donal T Skelly, Éadaoin W Griffin, Carol L Murray, Sarah Harney, Conor O'Boyle, Edel Hennessy, Marc-Andre Dansereau, Arshed Nazmi, Lucas Tortorelli, J Nicholas Rawlins, David M Bannerman, Colm Cunningha. Correction: Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms. Molecular psychiatry. vol 24. issue 10. 2020-05-11. PMID:30890763. |
this has now been corrected to: "direct application of il-1β to ex vivo hippocampal slices induced non-synaptic depolarisation and irreversible loss of membrane potential in ca1 neurons from diseased animals and systemic lps increased apoptosis in the degenerating brain, in an il-1ri-dependent fashion". |
2020-05-11 |
2023-08-13 |
Not clear |
| Fernanda Huf, Solange Bandiera, Carolina B Müller, Luiza Gea, Fabiano B Carvalho, Francine L Rahmeier, Keli C Reiter, Lucas S Tortorelli, Rosane Gomez, Marilda da Cruz Fernande. Comparative study on the effects of cigarette smoke exposure, ethanol consumption and association: Behavioral parameters, apoptosis, glial fibrillary acid protein and S100β immunoreactivity in different regions of the rat hippocampus. Alcohol (Fayetteville, N.Y.). vol 77. 2020-05-06. PMID:30870710. |
comparative study on the effects of cigarette smoke exposure, ethanol consumption and association: behavioral parameters, apoptosis, glial fibrillary acid protein and s100β immunoreactivity in different regions of the rat hippocampus. |
2020-05-06 |
2023-08-13 |
rat |
| Fernanda Huf, Solange Bandiera, Carolina B Müller, Luiza Gea, Fabiano B Carvalho, Francine L Rahmeier, Keli C Reiter, Lucas S Tortorelli, Rosane Gomez, Marilda da Cruz Fernande. Comparative study on the effects of cigarette smoke exposure, ethanol consumption and association: Behavioral parameters, apoptosis, glial fibrillary acid protein and S100β immunoreactivity in different regions of the rat hippocampus. Alcohol (Fayetteville, N.Y.). vol 77. 2020-05-06. PMID:30870710. |
the present study investigated the chronic effects of exposure to cigarette smoke and/or ethanol on behavioral parameters, apoptosis, and alteration in immunoreactivity of glial fibrillary acid protein (gfap) and s100β in the ca1, ca3, and dentate gyrus (dg) of the rat hippocampus. |
2020-05-06 |
2023-08-13 |
rat |
| Sabrina Ceccariglia, Alessandra Alvino, Aurora Del Fà, Ornella Parolini, Fabrizio Michetti, Carlo Gangitan. Autophagy is Activated International journal of molecular sciences. vol 21. issue 1. 2020-05-06. PMID:31881802. |
this study aimed to investigate the autophagy and apoptosis signaling pathways in hippocampal neurons of tmt-treated (wistar) rats to explore molecular mechanisms involved in toxicant-induced neuronal injury. |
2020-05-06 |
2023-08-13 |
rat |