| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Yeşil, I Tuğl. The relation of oxidative stress and apoptosis to histopathologic alterations in the lungs as a result of global cerebral ischemia. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 94. issue 8. 2020-04-03. PMID:31373845. |
in the gi and ir groups, apoptosis and necrosis were observed in the hippocampus. |
2020-04-03 |
2023-08-13 |
rat |
| Haiyang Zhang, Mian Wei, Xiangyu Lu, Qinghong Sun, Chuqiao Wang, Jiuyan Zhang, Honggang Fa. Aluminum trichloride caused hippocampal neural cells death and subsequent depression-like behavior in rats via the activation of IL-1β/JNK signaling pathway. The Science of the total environment. vol 715. 2020-04-03. PMID:32007895. |
however, it remains unclear whether il-1β/jnk signaling pathway is involving in the regulation of al-induced hippocampal neural cells apoptosis and necroptosis. |
2020-04-03 |
2023-08-13 |
rat |
| Changliang Zhang, Jing Wang, Jinling Zhu, Yabing Chen, Xiaodong Ha. Microcystin-leucine-arginine induced neurotoxicity by initiating mitochondrial fission in hippocampal neurons. The Science of the total environment. vol 703. 2020-03-31. PMID:31753492. |
in this research, we observed that mc-lr induced oxidative stress, mitochondrial fission and apoptosis in ht-22 hippocampal neurons. |
2020-03-31 |
2023-08-13 |
mouse |
| Changliang Zhang, Jing Wang, Jinling Zhu, Yabing Chen, Xiaodong Ha. Microcystin-leucine-arginine induced neurotoxicity by initiating mitochondrial fission in hippocampal neurons. The Science of the total environment. vol 703. 2020-03-31. PMID:31753492. |
moreover, further studies identified that mc-lr induced mitochondrial fragmentation via activating dynamin-related protein 1 (drp1) and mitochondrial fission factor (mff), contributing to apoptosis of hippocampal neuronal cells. |
2020-03-31 |
2023-08-13 |
mouse |
| Yann Estornes, Yves Dondelinger, Kathrin Weber, Inge Bruggeman, Adam Peall, Marion MacFarlane, Serge Lebecque, Peter Vandenabeele, Mathieu J M Bertran. N-glycosylation of mouse TRAIL-R restrains TRAIL-induced apoptosis. Cell death & disease. vol 9. issue 5. 2020-03-30. PMID:29717117. |
we found that tunicamycin (tu), but no other er stress inducers, sensitized mouse fibroblasts and hippocampal neuronal cells to trail-induced apoptosis. |
2020-03-30 |
2023-08-13 |
mouse |
| Sara Chavoshinezhad, Homa Mohseni Kouchesfahani, Abolhassan Ahmadiani, Leila Dargah. Interferon beta ameliorates cognitive dysfunction in a rat model of Alzheimer's disease: Modulation of hippocampal neurogenesis and apoptosis as underlying mechanism. Progress in neuro-psychopharmacology & biological psychiatry. vol 94. 2020-03-30. PMID:31152860. |
interferon beta ameliorates cognitive dysfunction in a rat model of alzheimer's disease: modulation of hippocampal neurogenesis and apoptosis as underlying mechanism. |
2020-03-30 |
2023-08-13 |
rat |
| Sara Chavoshinezhad, Homa Mohseni Kouchesfahani, Abolhassan Ahmadiani, Leila Dargah. Interferon beta ameliorates cognitive dysfunction in a rat model of Alzheimer's disease: Modulation of hippocampal neurogenesis and apoptosis as underlying mechanism. Progress in neuro-psychopharmacology & biological psychiatry. vol 94. 2020-03-30. PMID:31152860. |
neuronal apoptosis and impaired hippocampal neurogenesis are major players in cognitive/memory dysfunctions including alzheimer's disease (ad). |
2020-03-30 |
2023-08-13 |
rat |
| Sara Chavoshinezhad, Homa Mohseni Kouchesfahani, Abolhassan Ahmadiani, Leila Dargah. Interferon beta ameliorates cognitive dysfunction in a rat model of Alzheimer's disease: Modulation of hippocampal neurogenesis and apoptosis as underlying mechanism. Progress in neuro-psychopharmacology & biological psychiatry. vol 94. 2020-03-30. PMID:31152860. |
in this study, we examined the effect of ifnβ on memory impairment as well as hippocampal neurogenesis and apoptosis in a rat model of ad. |
2020-03-30 |
2023-08-13 |
rat |
| Sara Chavoshinezhad, Homa Mohseni Kouchesfahani, Abolhassan Ahmadiani, Leila Dargah. Interferon beta ameliorates cognitive dysfunction in a rat model of Alzheimer's disease: Modulation of hippocampal neurogenesis and apoptosis as underlying mechanism. Progress in neuro-psychopharmacology & biological psychiatry. vol 94. 2020-03-30. PMID:31152860. |
moreover, in parallel with reducing apoptosis and neural loss in the hippocampal subfields, ifnβ decreased ectopic neurogenesis in the ca1 and ca3 regions of the ad rat hippocampus. |
2020-03-30 |
2023-08-13 |
rat |
| Franciele Martini, Suzan Gonçalves Rosa, Isabella Pregardier Klann, Bruna Cruz Weber Fulco, Fabiano Barbosa Carvalho, Francine Luciano Rahmeier, Marilda Cruz Fernandes, Cristina Wayne Nogueir. A multifunctional compound ebselen reverses memory impairment, apoptosis and oxidative stress in a mouse model of sporadic Alzheimer's disease. Journal of psychiatric research. vol 109. 2020-03-27. PMID:30521994. |
the aim of the present study was to investigate whether ebselen (1-10 mg/kg), a multifunctional selenoorganic compound, ameliorates memory impairment, hippocampal oxidative stress, apoptosis and cell proliferation in a mouse model of sporadic ad induced by icv stz (3 mg/kg, 1 μl/min). |
2020-03-27 |
2023-08-13 |
mouse |
| Franciele Martini, Suzan Gonçalves Rosa, Isabella Pregardier Klann, Bruna Cruz Weber Fulco, Fabiano Barbosa Carvalho, Francine Luciano Rahmeier, Marilda Cruz Fernandes, Cristina Wayne Nogueir. A multifunctional compound ebselen reverses memory impairment, apoptosis and oxidative stress in a mouse model of sporadic Alzheimer's disease. Journal of psychiatric research. vol 109. 2020-03-27. PMID:30521994. |
in conclusion, the multifunctional selenoorganic compound ebselen was effective to reverse memory impairment, hippocampal oxidative stress and apoptosis in a mouse model of sporadic ad induced by icv stz. |
2020-03-27 |
2023-08-13 |
mouse |
| Xuze Li, Lining Huang, Zhifang Zhao, Lijun Bo, Rongtian Kang, Jiaojiao Yang, Zhenming Don. The protective effect of the Rho-kinase inhibitor hydroxyfasudil on propofol-induced hippocampal neuron apoptosis in neonatal rats. International journal of clinical and experimental pathology. vol 11. issue 9. 2020-03-25. PMID:31949854. |
the protective effect of the rho-kinase inhibitor hydroxyfasudil on propofol-induced hippocampal neuron apoptosis in neonatal rats. |
2020-03-25 |
2023-08-13 |
rat |
| Jun Lu, Nina Zhou, Ping Yang, Lanqiuzi Deng, Ganzhe Li. MicroRNA-27a-3p Downregulation Inhibits Inflammatory Response and Hippocampal Neuronal Cell Apoptosis by Upregulating Mitogen-Activated Protein Kinase 4 (MAP2K4) Expression in Epilepsy: In Vivo and In Vitro Studies. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-03-23. PMID:31710596. |
microrna-27a-3p downregulation inhibits inflammatory response and hippocampal neuronal cell apoptosis by upregulating mitogen-activated protein kinase 4 (map2k4) expression in epilepsy: in vivo and in vitro studies. |
2020-03-23 |
2023-08-13 |
rat |
| Jun Lu, Nina Zhou, Ping Yang, Lanqiuzi Deng, Ganzhe Li. MicroRNA-27a-3p Downregulation Inhibits Inflammatory Response and Hippocampal Neuronal Cell Apoptosis by Upregulating Mitogen-Activated Protein Kinase 4 (MAP2K4) Expression in Epilepsy: In Vivo and In Vitro Studies. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-03-23. PMID:31710596. |
mir-27a-3p inhibitor also inhibited apoptosis of hippocampal neurons in epileptic rats, promoted bcl2 expression, and decreased bax and caspase3 expression. |
2020-03-23 |
2023-08-13 |
rat |
| Jun Lu, Nina Zhou, Ping Yang, Lanqiuzi Deng, Ganzhe Li. MicroRNA-27a-3p Downregulation Inhibits Inflammatory Response and Hippocampal Neuronal Cell Apoptosis by Upregulating Mitogen-Activated Protein Kinase 4 (MAP2K4) Expression in Epilepsy: In Vivo and In Vitro Studies. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-03-23. PMID:31710596. |
conclusions our preliminary findings indicated that mir-27a-3p inhibitor protected against epilepsy-induced inflammatory response and hippocampal neuronal apoptosis by targeting map2k4. |
2020-03-23 |
2023-08-13 |
rat |
| Bin Yan, Jingbo Wang, Guoqing Tian, Hong Zhang, Yuqin Li. Effect of icariin on apoptosis in hippocampal neurons cultured in high glucose. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. vol 38. issue 4. 2020-03-18. PMID:32186080. |
effect of icariin on apoptosis in hippocampal neurons cultured in high glucose. |
2020-03-18 |
2023-08-13 |
Not clear |
| Bin Yan, Jingbo Wang, Guoqing Tian, Hong Zhang, Yuqin Li. Effect of icariin on apoptosis in hippocampal neurons cultured in high glucose. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. vol 38. issue 4. 2020-03-18. PMID:32186080. |
to investigate effect of icariin on apoptosis in hippocampal neurons cultured in high glucose, and the possible mechanism behind the action. |
2020-03-18 |
2023-08-13 |
Not clear |
| Ji-Peng Shi, Wei Fu, Jing Li. -3 PUFA Attenuates LPS-Induced Neuro-Injury of Neonatal Rats through the PI3K/AKT Pathway. Neuroscience. vol 414. 2020-03-13. PMID:31260648. |
in this study, newborn sd rats were intraperitoneally injected with lps or < omega>-3 pufa, and the proliferation and apoptosis of neurocytes in the hippocampus were measured by tunel and brdu. |
2020-03-13 |
2023-08-13 |
rat |
| Fei Guo, Su Zhao Zhang, Shi Yu Chen, Chuang Zhang, Xiao Qi Zhang, Fei Gao, Ze Hui Wu, Wen Tao Yu, Yu Lei Liang, Hui Zhen Zhan. [Electroacupuncture improved learning-memory ability by reducing hippocampal apoptosis and suppressing JNK signaling in rats with vascular dementia]. Zhen ci yan jiu = Acupuncture research. vol 45. issue 1. 2020-03-12. PMID:32144904. |
[electroacupuncture improved learning-memory ability by reducing hippocampal apoptosis and suppressing jnk signaling in rats with vascular dementia]. |
2020-03-12 |
2023-08-13 |
rat |
| Solmaz Fallahi, Shirin Babri, Fereshteh Farajdokht, Rafighe Ghiasi, Hamid Soltani Zangbar, Pouran Karimi, Gisou Mohadde. Neuroprotective effect of ghrelin in methamphetamine-treated male rats. Neuroscience letters. vol 707. 2020-03-11. PMID:31152850. |
tunel assay was performed to detect hippocampal neuronal apoptosis. |
2020-03-11 |
2023-08-13 |
rat |