| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cheng Zhu, Li Hui, Ke Zheng, Linjing Liu, Jiahong Liu, Wei L. Silencing of RGS2 enhances hippocampal neuron regeneration and rescues depression-like behavioral impairments through activation of cAMP pathway. Brain research. vol 1746. 2021-10-01. PMID:32679115. |
furthermore, regeneration was enhanced and apoptosis was repressed in mouse hippocampal neurons in the presence of rgs2 knockdown and forskolin. |
2021-10-01 |
2023-08-13 |
mouse |
| Tiyasha Sarkar, Nisha Patro, Ishan Kumar Patr. Neuronal changes and cognitive deficits in a multi-hit rat model following cumulative impact of early life stressors. Biology open. vol 9. issue 9. 2021-10-01. PMID:32878878. |
hippocampal cellular apoptosis, β iii tubulin catastrophe, altered neuronal profiling and spatial memory impairments were assessed at pnd 180, using specific immunohistochemical markers (active caspase 3, β iii tubulin, doublecortin), golgi studies and cognitive mazes (morris water maze and t maze). |
2021-10-01 |
2023-08-13 |
rat |
| Bruna Ferrary Deniz, Heloísa Deola Confortim, Patrícia Maidana Miguel, Loise Bronauth, Isabela R Fernandes, Alysson R Muotri, Lenir Orlandi Pereir. High gestational folic acid supplementation prevents hypoxia-ischemia-induced caspase-3 augmenting without changing synapsin and H3 methylation levels in the rat hippocampus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 81. issue 6. 2021-10-01. PMID:34021639. |
considering that fa supplementation is already used in pregnant women and that hi occurs in the peripartum period, this study was designated to evaluate how gestational fa supplementation and neonatal hi affect: apoptosis (caspase-3) and expression of synaptic proteins (synapsin and psd-95) and the methylation of histone h3 lysine (k) 4 and 27 in the rat hippocampus. |
2021-10-01 |
2023-08-13 |
rat |
| Manish Shukla, Kumar Vyonkesh Mani, Deepshikha, Sangeeta Shukla, Neeru Kapoo. Moderate noise associated oxidative stress with concomitant memory impairment, neuro-inflammation and neurodegeneration. Brain, behavior, & immunity - health. vol 5. 2021-10-01. PMID:34589861. |
further, the underlying mechanism pertaining to apoptosis was investigated by immuno-histological studies through assessment of caspase-3 and tunel assay as well as morphological parameters, namely nissl bodies in ca1, ca3 and dg regions of hippocampus. |
2021-10-01 |
2023-08-13 |
rat |
| Yangliang Yang, Jing Yi, Mengzhi Pan, Baoji Hu, Hongwei Dua. Edaravone alleviated propofol-induced neural injury in developing rats by BDNF/TrkB pathway. Journal of cellular and molecular medicine. vol 25. issue 11. 2021-09-30. PMID:33932098. |
firstly, an observation was made of apoptosis and neuroinflammation in the hippocampus of developing under the influence of propofol. |
2021-09-30 |
2023-08-13 |
rat |
| Yangliang Yang, Jing Yi, Mengzhi Pan, Baoji Hu, Hongwei Dua. Edaravone alleviated propofol-induced neural injury in developing rats by BDNF/TrkB pathway. Journal of cellular and molecular medicine. vol 25. issue 11. 2021-09-30. PMID:33932098. |
additionally, the intraperitoneal injection of edaravone, the intraperitoneal injection of the brain-derived neurotrophic factor (bdnf)-mimicking small compound (7,8 dihydroxyflavone) and the intracranial injection of the exogenous bdnf were all respectively effective in alleviating the propofol-induced neural apoptosis and inflammation in the hippocampus. |
2021-09-30 |
2023-08-13 |
rat |
| Saifudeen Ismael, Wajidunnisa, Kazuko Sakata, Michael P McDonald, Francesca-Fang Liao, Tauheed Ishra. ER stress associated TXNIP-NLRP3 inflammasome activation in hippocampus of human Alzheimer's disease. Neurochemistry international. vol 148. 2021-09-30. PMID:34153352. |
further, elevated expression of effector molecules of nlrp3 inflammasome activation such as apoptosis associated speck-like protein (asc), cleaved caspase-1 and cleaved interleukin-1β were observed in the ad hippocampus. |
2021-09-30 |
2023-08-13 |
human |
| Jianhua Qin, Qingjun Ma, Dongmei M. Low-dose Sevoflurane Attenuates Cardiopulmonary Bypass (CPB)- induced Postoperative Cognitive Dysfunction (POCD) by Regulating Hippocampus Apoptosis via PI3K/AKT Pathway. Current neurovascular research. vol 17. issue 3. 2021-09-29. PMID:32400333. |
low-dose sevoflurane attenuates cardiopulmonary bypass (cpb)- induced postoperative cognitive dysfunction (pocd) by regulating hippocampus apoptosis via pi3k/akt pathway. |
2021-09-29 |
2023-08-13 |
Not clear |
| Jianhua Qin, Qingjun Ma, Dongmei M. Low-dose Sevoflurane Attenuates Cardiopulmonary Bypass (CPB)- induced Postoperative Cognitive Dysfunction (POCD) by Regulating Hippocampus Apoptosis via PI3K/AKT Pathway. Current neurovascular research. vol 17. issue 3. 2021-09-29. PMID:32400333. |
cardiopulmonary bypass (cpb) caused postoperative cognitive dysfunction (pocd) was characterized by hippocampus apoptosis, which seriously limited the therapeutic efficacy and utilization of cpb in clinic. |
2021-09-29 |
2023-08-13 |
Not clear |
| Zhiyin Tang, Fan Yang, Yunxia Dong, Chenguang Ma, Shiwei Sun, Yangyang Shan, Yongfang Zhang, Hongtao Li. Midazolam contributes to neuroprotection against hypoxia/reoxygenation-induced brain injury in neonatal rats via regulation of EAAT2. Brain research bulletin. vol 161. 2021-09-29. PMID:32433937. |
pretreatment with midazolam reversed h/r-induced apoptosis and downregulation of eaat2 mrna and protein expression in the hippocampus. |
2021-09-29 |
2023-08-13 |
rat |
| Yiyun Ding, Hongxia Zhang, Zhaojun Liu, Qiuping Li, Yujiao Guo, Ye Chen, Yue Chang, Hongyan Cu. Carnitine palmitoyltransferase 1 (CPT1) alleviates oxidative stress and apoptosis of hippocampal neuron in response to beta-Amyloid peptide fragment Aβ Bioengineered. vol 12. issue 1. 2021-09-27. PMID:34424821. |
carnitine palmitoyltransferase 1 (cpt1) alleviates oxidative stress and apoptosis of hippocampal neuron in response to beta-amyloid peptide fragment aβ cpt1c, which is expressed in hippocampus, influences ceramide level, endogenous cannabinoid and oxidation process, as well as plays an important role in various brain functions such as learning. |
2021-09-27 |
2023-08-13 |
Not clear |
| Yuqin Wu, Lin Fan, Yun Wang, Jing Ding, Rongfu Wan. Isorhamnetin Alleviates High Glucose-Aggravated Inflammatory Response and Apoptosis in Oxygen-Glucose Deprivation and Reoxygenation-Induced HT22 Hippocampal Neurons Through Akt/SIRT1/Nrf2/HO-1 Signaling Pathway. Inflammation. vol 44. issue 5. 2021-09-24. PMID:33999329. |
isorhamnetin alleviates high glucose-aggravated inflammatory response and apoptosis in oxygen-glucose deprivation and reoxygenation-induced ht22 hippocampal neurons through akt/sirt1/nrf2/ho-1 signaling pathway. |
2021-09-24 |
2023-08-13 |
Not clear |
| Wenqian Zhang, Jun Hong, Hanwen Zhang, Wencheng Zheng, Ying Yan. Astrocyte-derived exosomes protect hippocampal neurons after traumatic brain injury by suppressing mitochondrial oxidative stress and apoptosis. Aging. vol 13. issue 17. 2021-09-24. PMID:34516406. |
astrocyte-derived exosomes protect hippocampal neurons after traumatic brain injury by suppressing mitochondrial oxidative stress and apoptosis. |
2021-09-24 |
2023-08-13 |
mouse |
| Yanhui Yu, Linjun Du, Jinxu Zhan. Febrile Seizure-Related miR-148a-3p Exerts Neuroprotection by Promoting the Proliferation of Hippocampal Neurons in Children with Temporal Lobe Epilepsy. Developmental neuroscience. vol 43. issue 5. 2021-09-23. PMID:34348296. |
the effects of mir-148a-3p on hippocampal neuronal viability and apoptosis rate were detected by mtt and flow cytometry, respectively. |
2021-09-23 |
2023-08-13 |
Not clear |
| Yanhui Yu, Linjun Du, Jinxu Zhan. Febrile Seizure-Related miR-148a-3p Exerts Neuroprotection by Promoting the Proliferation of Hippocampal Neurons in Children with Temporal Lobe Epilepsy. Developmental neuroscience. vol 43. issue 5. 2021-09-23. PMID:34348296. |
hippocampal neurons treated with magnesium-free medium were used as an in vitro model of tle and showed significantly increased mir-148a-3p, decreased cell viability, and increased cell apoptosis, while these changes were eliminated markedly by mir-148a-3p knockdown. |
2021-09-23 |
2023-08-13 |
Not clear |
| Shweta Goyal, Saurabh Tiwari, Brashket Seth, Ankit Tandon, Jai Shankar, Meetali Sinha, Sangh Jyoti Singh, Smriti Priya, Rajnish Kumar Chaturved. Bisphenol-A inhibits mitochondrial biogenesis via impairment of GFER mediated mitochondrial protein import in the rat brain hippocampus. Neurotoxicology. vol 85. 2021-09-22. PMID:33878312. |
overall, our study implicates gfer as a potential target for impaired mitochondrial protein machinery, biogenesis, and apoptosis against bpa neurotoxicity in the rat hippocampus. |
2021-09-22 |
2023-08-13 |
rat |
| Bin Sun, Xiaoxian Liu, Han Peng, Xin Xiang, Hua Yan. Circular RNA _NLRP1 targets mouse microRNA-199b-3p to regulate apoptosis and pyroptosis of hippocampal neuron under oxygen-glucose deprivation exposure. Bioengineered. vol 12. issue 1. 2021-09-22. PMID:34227902. |
circular rna _nlrp1 targets mouse microrna-199b-3p to regulate apoptosis and pyroptosis of hippocampal neuron under oxygen-glucose deprivation exposure. |
2021-09-22 |
2023-08-13 |
mouse |
| Zhixiong Li, Guangxu Xiao, Huanyi Wang, Shuang He, Yan Zh. A preparation of Ginkgo biloba L. leaves extract inhibits the apoptosis of hippocampal neurons in post-stroke mice via regulating the expression of Bax/Bcl-2 and Caspase-3. Journal of ethnopharmacology. vol 280. 2021-09-20. PMID:34343651. |
a preparation of ginkgo biloba l. leaves extract inhibits the apoptosis of hippocampal neurons in post-stroke mice via regulating the expression of bax/bcl-2 and caspase-3. |
2021-09-20 |
2023-08-13 |
mouse |
| Hamid Soltani Zangbar, Tahereh Ghadiri, Manuchehr Seyedi Vafaee, Abbas Ebrahimi Kalan, Mohammad Karimipour, Solmaz Fallahi, Meysam Ghorbani, Parviz Shahab. A potential entanglement between the spinal cord and hippocampus: Theta rhythm correlates with neurogenesis deficiency following spinal cord injury in male rats. Journal of neuroscience research. vol 98. issue 12. 2021-09-17. PMID:32875652. |
our research revealed that sci could induce changes not only in the neurogenesis and apoptosis rate of the hippocampus but also in theta power as well as receptors involving in the generation of this rhythm. |
2021-09-17 |
2023-08-13 |
human |
| Serpil Ünver Saraydin, Berna Özdenoglu Kutlu, Dursun Saraydı. Effects of diabetes on apoptosis and mitosis in rat hippocampus. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 96. issue 6. 2021-09-17. PMID:32938250. |
effects of diabetes on apoptosis and mitosis in rat hippocampus. |
2021-09-17 |
2023-08-13 |
rat |