| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yangliang Yang, Jing Yi, Mengzhi Pan, Baoji Hu, Hongwei Dua. Edaravone alleviated propofol-induced neural injury in developing rats by BDNF/TrkB pathway. Journal of cellular and molecular medicine. vol 25. issue 11. 2021-09-30. PMID:33932098. |
firstly, an observation was made of apoptosis and neuroinflammation in the hippocampus of developing under the influence of propofol. |
2021-09-30 |
2023-08-13 |
rat |
| Yangliang Yang, Jing Yi, Mengzhi Pan, Baoji Hu, Hongwei Dua. Edaravone alleviated propofol-induced neural injury in developing rats by BDNF/TrkB pathway. Journal of cellular and molecular medicine. vol 25. issue 11. 2021-09-30. PMID:33932098. |
additionally, the intraperitoneal injection of edaravone, the intraperitoneal injection of the brain-derived neurotrophic factor (bdnf)-mimicking small compound (7,8 dihydroxyflavone) and the intracranial injection of the exogenous bdnf were all respectively effective in alleviating the propofol-induced neural apoptosis and inflammation in the hippocampus. |
2021-09-30 |
2023-08-13 |
rat |
| Saifudeen Ismael, Wajidunnisa, Kazuko Sakata, Michael P McDonald, Francesca-Fang Liao, Tauheed Ishra. ER stress associated TXNIP-NLRP3 inflammasome activation in hippocampus of human Alzheimer's disease. Neurochemistry international. vol 148. 2021-09-30. PMID:34153352. |
further, elevated expression of effector molecules of nlrp3 inflammasome activation such as apoptosis associated speck-like protein (asc), cleaved caspase-1 and cleaved interleukin-1β were observed in the ad hippocampus. |
2021-09-30 |
2023-08-13 |
human |
| Jianhua Qin, Qingjun Ma, Dongmei M. Low-dose Sevoflurane Attenuates Cardiopulmonary Bypass (CPB)- induced Postoperative Cognitive Dysfunction (POCD) by Regulating Hippocampus Apoptosis via PI3K/AKT Pathway. Current neurovascular research. vol 17. issue 3. 2021-09-29. PMID:32400333. |
low-dose sevoflurane attenuates cardiopulmonary bypass (cpb)- induced postoperative cognitive dysfunction (pocd) by regulating hippocampus apoptosis via pi3k/akt pathway. |
2021-09-29 |
2023-08-13 |
Not clear |
| Jianhua Qin, Qingjun Ma, Dongmei M. Low-dose Sevoflurane Attenuates Cardiopulmonary Bypass (CPB)- induced Postoperative Cognitive Dysfunction (POCD) by Regulating Hippocampus Apoptosis via PI3K/AKT Pathway. Current neurovascular research. vol 17. issue 3. 2021-09-29. PMID:32400333. |
cardiopulmonary bypass (cpb) caused postoperative cognitive dysfunction (pocd) was characterized by hippocampus apoptosis, which seriously limited the therapeutic efficacy and utilization of cpb in clinic. |
2021-09-29 |
2023-08-13 |
Not clear |
| Zhiyin Tang, Fan Yang, Yunxia Dong, Chenguang Ma, Shiwei Sun, Yangyang Shan, Yongfang Zhang, Hongtao Li. Midazolam contributes to neuroprotection against hypoxia/reoxygenation-induced brain injury in neonatal rats via regulation of EAAT2. Brain research bulletin. vol 161. 2021-09-29. PMID:32433937. |
pretreatment with midazolam reversed h/r-induced apoptosis and downregulation of eaat2 mrna and protein expression in the hippocampus. |
2021-09-29 |
2023-08-13 |
rat |
| Yiyun Ding, Hongxia Zhang, Zhaojun Liu, Qiuping Li, Yujiao Guo, Ye Chen, Yue Chang, Hongyan Cu. Carnitine palmitoyltransferase 1 (CPT1) alleviates oxidative stress and apoptosis of hippocampal neuron in response to beta-Amyloid peptide fragment Aβ Bioengineered. vol 12. issue 1. 2021-09-27. PMID:34424821. |
carnitine palmitoyltransferase 1 (cpt1) alleviates oxidative stress and apoptosis of hippocampal neuron in response to beta-amyloid peptide fragment aβ cpt1c, which is expressed in hippocampus, influences ceramide level, endogenous cannabinoid and oxidation process, as well as plays an important role in various brain functions such as learning. |
2021-09-27 |
2023-08-13 |
Not clear |
| Yuqin Wu, Lin Fan, Yun Wang, Jing Ding, Rongfu Wan. Isorhamnetin Alleviates High Glucose-Aggravated Inflammatory Response and Apoptosis in Oxygen-Glucose Deprivation and Reoxygenation-Induced HT22 Hippocampal Neurons Through Akt/SIRT1/Nrf2/HO-1 Signaling Pathway. Inflammation. vol 44. issue 5. 2021-09-24. PMID:33999329. |
isorhamnetin alleviates high glucose-aggravated inflammatory response and apoptosis in oxygen-glucose deprivation and reoxygenation-induced ht22 hippocampal neurons through akt/sirt1/nrf2/ho-1 signaling pathway. |
2021-09-24 |
2023-08-13 |
Not clear |
| Wenqian Zhang, Jun Hong, Hanwen Zhang, Wencheng Zheng, Ying Yan. Astrocyte-derived exosomes protect hippocampal neurons after traumatic brain injury by suppressing mitochondrial oxidative stress and apoptosis. Aging. vol 13. issue 17. 2021-09-24. PMID:34516406. |
astrocyte-derived exosomes protect hippocampal neurons after traumatic brain injury by suppressing mitochondrial oxidative stress and apoptosis. |
2021-09-24 |
2023-08-13 |
mouse |
| Yanhui Yu, Linjun Du, Jinxu Zhan. Febrile Seizure-Related miR-148a-3p Exerts Neuroprotection by Promoting the Proliferation of Hippocampal Neurons in Children with Temporal Lobe Epilepsy. Developmental neuroscience. vol 43. issue 5. 2021-09-23. PMID:34348296. |
the effects of mir-148a-3p on hippocampal neuronal viability and apoptosis rate were detected by mtt and flow cytometry, respectively. |
2021-09-23 |
2023-08-13 |
Not clear |
| Yanhui Yu, Linjun Du, Jinxu Zhan. Febrile Seizure-Related miR-148a-3p Exerts Neuroprotection by Promoting the Proliferation of Hippocampal Neurons in Children with Temporal Lobe Epilepsy. Developmental neuroscience. vol 43. issue 5. 2021-09-23. PMID:34348296. |
hippocampal neurons treated with magnesium-free medium were used as an in vitro model of tle and showed significantly increased mir-148a-3p, decreased cell viability, and increased cell apoptosis, while these changes were eliminated markedly by mir-148a-3p knockdown. |
2021-09-23 |
2023-08-13 |
Not clear |
| Shweta Goyal, Saurabh Tiwari, Brashket Seth, Ankit Tandon, Jai Shankar, Meetali Sinha, Sangh Jyoti Singh, Smriti Priya, Rajnish Kumar Chaturved. Bisphenol-A inhibits mitochondrial biogenesis via impairment of GFER mediated mitochondrial protein import in the rat brain hippocampus. Neurotoxicology. vol 85. 2021-09-22. PMID:33878312. |
overall, our study implicates gfer as a potential target for impaired mitochondrial protein machinery, biogenesis, and apoptosis against bpa neurotoxicity in the rat hippocampus. |
2021-09-22 |
2023-08-13 |
rat |
| Bin Sun, Xiaoxian Liu, Han Peng, Xin Xiang, Hua Yan. Circular RNA _NLRP1 targets mouse microRNA-199b-3p to regulate apoptosis and pyroptosis of hippocampal neuron under oxygen-glucose deprivation exposure. Bioengineered. vol 12. issue 1. 2021-09-22. PMID:34227902. |
circular rna _nlrp1 targets mouse microrna-199b-3p to regulate apoptosis and pyroptosis of hippocampal neuron under oxygen-glucose deprivation exposure. |
2021-09-22 |
2023-08-13 |
mouse |
| Zhixiong Li, Guangxu Xiao, Huanyi Wang, Shuang He, Yan Zh. A preparation of Ginkgo biloba L. leaves extract inhibits the apoptosis of hippocampal neurons in post-stroke mice via regulating the expression of Bax/Bcl-2 and Caspase-3. Journal of ethnopharmacology. vol 280. 2021-09-20. PMID:34343651. |
a preparation of ginkgo biloba l. leaves extract inhibits the apoptosis of hippocampal neurons in post-stroke mice via regulating the expression of bax/bcl-2 and caspase-3. |
2021-09-20 |
2023-08-13 |
mouse |
| Hamid Soltani Zangbar, Tahereh Ghadiri, Manuchehr Seyedi Vafaee, Abbas Ebrahimi Kalan, Mohammad Karimipour, Solmaz Fallahi, Meysam Ghorbani, Parviz Shahab. A potential entanglement between the spinal cord and hippocampus: Theta rhythm correlates with neurogenesis deficiency following spinal cord injury in male rats. Journal of neuroscience research. vol 98. issue 12. 2021-09-17. PMID:32875652. |
our research revealed that sci could induce changes not only in the neurogenesis and apoptosis rate of the hippocampus but also in theta power as well as receptors involving in the generation of this rhythm. |
2021-09-17 |
2023-08-13 |
human |
| Serpil Ünver Saraydin, Berna Özdenoglu Kutlu, Dursun Saraydı. Effects of diabetes on apoptosis and mitosis in rat hippocampus. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 96. issue 6. 2021-09-17. PMID:32938250. |
effects of diabetes on apoptosis and mitosis in rat hippocampus. |
2021-09-17 |
2023-08-13 |
rat |
| Xibin Zhou, Yuxing Zhang, Yiqian Jiang, Chunxiang Zhou, Yun Lin. Poria cocos polysaccharide attenuates damage of nervus in Alzheimer's disease rat model induced by D-galactose and aluminum trichloride. Neuroreport. vol 32. issue 8. 2021-09-17. PMID:33913927. |
moreover, pcp could reduce neuronal apoptosis in hippocampus of alzheimer's disease rats. |
2021-09-17 |
2023-08-13 |
rat |
| Alam Khan, Talukdar Mohammad Fahad, Tanjima Akther, Tanjeena Zaman, Md Faruk Hasan, Md Rafiqual Islam Khan, Mohammad Saiful Islam, Shuji Kish. Carbofuran accelerates the cellular senescence and declines the life span of spns1 mutant zebrafish. Journal of cellular and molecular medicine. vol 25. issue 2. 2021-09-14. PMID:33277797. |
in mammals, carbofuran is known to cause several untoward effects, such as apoptosis in the hippocampal neuron, oxidative stress, loss of memory and chromosomal anomalies. |
2021-09-14 |
2023-08-13 |
zebrafish |
| Wenxiang Fan, Ying Zhang, Xiaomin Li, Chi X. S-oxiracetam Facilitates Cognitive Restoration after Ischemic Stroke by Activating α7nAChR and the PI3K-Mediated Pathway. Neurochemical research. vol 46. issue 4. 2021-09-14. PMID:33481205. |
by using y-maze test, morris water maze, triphenyl tetrazolium chloride (ttc) staining, terminal deoxynucleotidyl transferase-mediated 2'-deoxyuridine 5'-triphosphate (dutp) nick end labeling (tunel) assay, hematoxylin and eosin, immunohistochemical staining and western blot to evaluate the protective effect of s-orc on cognitive recovery, we were able to confirm that s-orc ameliorated spatial learning impairment, tissue loss, and hippocampal neuronal apoptosis and injury induced by mcao/r in rats. |
2021-09-14 |
2023-08-13 |
rat |
| Parul Gupta, Shubhangini Tiwari, Abhishek Singh, Amit Pal, Amit Mishra, Sarika Sing. Rivastigmine attenuates the Alzheimer's disease related protein degradation and apoptotic neuronal death signalling. The Biochemical journal. vol 478. issue 7. 2021-09-13. PMID:33660768. |
the known inhibitory effect of rivastigmine on cognition and acetylcholinesterase activity was observed in both cortex and hippocampus and further its effect on tau level, amyloid aggregation, biochemical alterations, endoplasmic reticulum (er) stress, calcium homeostasis, proteasome activity and apoptosis was estimated. |
2021-09-13 |
2023-08-13 |
rat |