| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xibin Zhou, Yuxing Zhang, Yiqian Jiang, Chunxiang Zhou, Yun Lin. Poria cocos polysaccharide attenuates damage of nervus in Alzheimer's disease rat model induced by D-galactose and aluminum trichloride. Neuroreport. vol 32. issue 8. 2021-09-17. PMID:33913927. |
moreover, pcp could reduce neuronal apoptosis in hippocampus of alzheimer's disease rats. |
2021-09-17 |
2023-08-13 |
rat |
| Alam Khan, Talukdar Mohammad Fahad, Tanjima Akther, Tanjeena Zaman, Md Faruk Hasan, Md Rafiqual Islam Khan, Mohammad Saiful Islam, Shuji Kish. Carbofuran accelerates the cellular senescence and declines the life span of spns1 mutant zebrafish. Journal of cellular and molecular medicine. vol 25. issue 2. 2021-09-14. PMID:33277797. |
in mammals, carbofuran is known to cause several untoward effects, such as apoptosis in the hippocampal neuron, oxidative stress, loss of memory and chromosomal anomalies. |
2021-09-14 |
2023-08-13 |
zebrafish |
| Wenxiang Fan, Ying Zhang, Xiaomin Li, Chi X. S-oxiracetam Facilitates Cognitive Restoration after Ischemic Stroke by Activating α7nAChR and the PI3K-Mediated Pathway. Neurochemical research. vol 46. issue 4. 2021-09-14. PMID:33481205. |
by using y-maze test, morris water maze, triphenyl tetrazolium chloride (ttc) staining, terminal deoxynucleotidyl transferase-mediated 2'-deoxyuridine 5'-triphosphate (dutp) nick end labeling (tunel) assay, hematoxylin and eosin, immunohistochemical staining and western blot to evaluate the protective effect of s-orc on cognitive recovery, we were able to confirm that s-orc ameliorated spatial learning impairment, tissue loss, and hippocampal neuronal apoptosis and injury induced by mcao/r in rats. |
2021-09-14 |
2023-08-13 |
rat |
| Parul Gupta, Shubhangini Tiwari, Abhishek Singh, Amit Pal, Amit Mishra, Sarika Sing. Rivastigmine attenuates the Alzheimer's disease related protein degradation and apoptotic neuronal death signalling. The Biochemical journal. vol 478. issue 7. 2021-09-13. PMID:33660768. |
the known inhibitory effect of rivastigmine on cognition and acetylcholinesterase activity was observed in both cortex and hippocampus and further its effect on tau level, amyloid aggregation, biochemical alterations, endoplasmic reticulum (er) stress, calcium homeostasis, proteasome activity and apoptosis was estimated. |
2021-09-13 |
2023-08-13 |
rat |
| Susan Jung, Klara Terörde, Helmuth-Günther Dörr, Regina Trollman. Recombinant Human Growth Hormone Activates Neuroprotective Growth Factors in Hypoxic Brain Injury in Neonatal Mice. Endocrinology. vol 162. issue 3. 2021-09-10. PMID:33545716. |
in the developing brain, rhgh treatment led to a notable reduction of apoptosis in the subventricular zone and hippocampus (p < .05), abolished hypoxia-induced downregulation of igf-1/igf-2 expression (p < .05), and led to a significant accumulation of endogenous epo protein and anti-inflammatory effects through modulation of interleukin-1β and tumor necrosis factor α signaling as well as upregulation of cerebral phosphorylated extracellularly regulated kinase 1/2 levels (erk1/2). |
2021-09-10 |
2023-08-13 |
mouse |
| Yahong Cheng, Xin Zeng, Qianting Mai, Xinying Bai, Yuan Jiang, Jinjin Li, Shiqi Fan, Hong Din. Insulin injections inhibits PTZ-induced mitochondrial dysfunction, oxidative stress and neurological deficits via the SIRT1/PGC-1α/SIRT3 pathway. Biochimica et biophysica acta. Molecular basis of disease. vol 1867. issue 6. 2021-09-10. PMID:33727197. |
additionally, insulin pretreatment upregulated bcl-2, downregulated bax, and then played a neuroprotective role against hippocampal neuron apoptosis. |
2021-09-10 |
2023-08-13 |
mouse |
| RETRACTION NOTICE: MicroRNA-132 protects hippocampal neurons against oxygen-glucose deprivation-induced apoptosis. International journal of immunopathology and pharmacology. vol 35. 2021-09-09. PMID:34474600. |
retraction notice: microrna-132 protects hippocampal neurons against oxygen-glucose deprivation-induced apoptosis. |
2021-09-09 |
2023-08-13 |
Not clear |
| Wei Tu, Weifeng Li, Xingen Zhu, Linlin X. Di-2-ethylhexyl phthalate (DEHP) induces apoptosis of mouse HT22 hippocampal neuronal cells via oxidative stress. Toxicology and industrial health. vol 36. issue 11. 2021-09-08. PMID:32909914. |
di-2-ethylhexyl phthalate (dehp) induces apoptosis of mouse ht22 hippocampal neuronal cells via oxidative stress. |
2021-09-08 |
2023-08-13 |
mouse |
| Yang Huang, Xuhui Gao, Xiang Zhou, Yu Zhang, ZhiTian Tan, ShuiBo Zh. Remote Ischemic Postconditioning Inhibited Mitophagy to Achieve Neuroprotective Effects in the Rat Model of Cardiac Arrest. Neurochemical research. vol 46. issue 3. 2021-09-07. PMID:33409854. |
the apoptosis of hippocampal neurons was detected by flow and tunel. |
2021-09-07 |
2023-08-13 |
rat |
| Yang Huang, Xuhui Gao, Xiang Zhou, Yu Zhang, ZhiTian Tan, ShuiBo Zh. Remote Ischemic Postconditioning Inhibited Mitophagy to Achieve Neuroprotective Effects in the Rat Model of Cardiac Arrest. Neurochemical research. vol 46. issue 3. 2021-09-07. PMID:33409854. |
furthermore, ri-postc could also reduce the rate of hippocampal nerve apoptosis and the damage of hippocampal neurons after cpr. |
2021-09-07 |
2023-08-13 |
rat |
| Congshan Jiang, Thiago Arzua, Yasheng Yan, Xiaowen Ba. Expression Signature of lncRNAs and mRNAs in Sevoflurane-Induced Mouse Brain Injury: Implication of Involvement of Wide Molecular Networks and Pathways. International journal of molecular sciences. vol 22. issue 3. 2021-09-07. PMID:33573239. |
these dysregulated lncrnas/mrnas form wide molecular networks that might contribute to various functional neurological disease pathways in the hippocampus, resulting in the observed acute apoptosis and impaired long-term memory. |
2021-09-07 |
2023-08-13 |
mouse |
| Zhujun Zhu, Sihong Wang, Qi Cao, Gang L. CircUBQLN1 Promotes Proliferation but Inhibits Apoptosis and Oxidative Stress of Hippocampal Neurons in Epilepsy via the miR-155-Mediated SOX7 Upregulation. Journal of molecular neuroscience : MN. vol 71. issue 9. 2021-09-07. PMID:33835399. |
circubqln1 promotes proliferation but inhibits apoptosis and oxidative stress of hippocampal neurons in epilepsy via the mir-155-mediated sox7 upregulation. |
2021-09-07 |
2023-08-13 |
Not clear |
| Yu Lei, Xiaoyuan Jin, Mingli Sun, Zhiyong J. miR-129-5p Ameliorates Ischemic Brain Injury by Binding to SIAH1 and Activating the mTOR Signaling Pathway. Journal of molecular neuroscience : MN. vol 71. issue 9. 2021-09-07. PMID:34355355. |
apoptosis of hippocampal neuronal cells was assessed by annexin v-fitc/pi staining and tunel staining. |
2021-09-07 |
2023-08-13 |
mouse |
| Yu Lei, Xiaoyuan Jin, Mingli Sun, Zhiyong J. miR-129-5p Ameliorates Ischemic Brain Injury by Binding to SIAH1 and Activating the mTOR Signaling Pathway. Journal of molecular neuroscience : MN. vol 71. issue 9. 2021-09-07. PMID:34355355. |
additionally, enforced mir-129-5p inhibited the apoptosis of ogd-induced cells and decreased the cerebral infarct area, neurological scores and apoptosis of hippocampal neuronal cells by downregulating siah1 and activating the mtor signaling pathway. |
2021-09-07 |
2023-08-13 |
mouse |
| Chunli Li, Haipeng Wang, Min Wang, Chunyun Chen, Fei Bai, Mengqi Ban, Chunfu W. Oxytocin Attenuates Methamphetamine-Induced Apoptosis Frontiers in pharmacology. vol 12. 2021-09-07. PMID:34483895. |
in conclusion, our study proved that pre-administration of ot could significantly attenuate hippocampal neuron apoptosis induced by meth. |
2021-09-07 |
2023-08-13 |
rat |
| Chunli Li, Haipeng Wang, Min Wang, Chunyun Chen, Fei Bai, Mengqi Ban, Chunfu W. Oxytocin Attenuates Methamphetamine-Induced Apoptosis Frontiers in pharmacology. vol 12. 2021-09-07. PMID:34483895. |
oxytocin receptor activation is involved in the preventive effect of ot on meth-induced apoptosis in rat hippocampal neurons. |
2021-09-07 |
2023-08-13 |
rat |
| Thiago G Bassi, Elizabeth C Rohrs, Karl C Fernandez, Marlena Ornoswska, Michelle Nicholas, Matt Gani, Doug Evans, Steven C Reynold. Transvenous Diaphragm Neurostimulation Mitigates Ventilation-associated Brain Injury. American journal of respiratory and critical care medicine. 2021-09-07. PMID:34491883. |
mechanical ventilation (mv) is associated with hippocampal apoptosis and inflammation, and it is important to study strategies to mitigate them. |
2021-09-07 |
2023-08-13 |
Not clear |
| Alireza Mirkheshti, Alireza Shakeri, Elham Memary, Mansoureh Baniasadi, Jalal Zaringhalam, Ardeshir Tajbakhsh, Marzieh Mirzaei, Elena La. Maternal sciatic nerve administered bupivacaine induces hippocampal cell apoptosis in offspring. BMC anesthesiology. vol 20. issue 1. 2021-09-06. PMID:32894054. |
maternal sciatic nerve administered bupivacaine induces hippocampal cell apoptosis in offspring. |
2021-09-06 |
2023-08-13 |
Not clear |
| Alireza Mirkheshti, Alireza Shakeri, Elham Memary, Mansoureh Baniasadi, Jalal Zaringhalam, Ardeshir Tajbakhsh, Marzieh Mirzaei, Elena La. Maternal sciatic nerve administered bupivacaine induces hippocampal cell apoptosis in offspring. BMC anesthesiology. vol 20. issue 1. 2021-09-06. PMID:32894054. |
hence, this study was design to investigate the effects of maternal bupivacaine use on fetus hippocampal cell apoptosis and the possible related mechanism. |
2021-09-06 |
2023-08-13 |
Not clear |
| Alireza Torfeh, Zohreh Abdolmaleki, Sepideh Nazarian, Seyed Hamed Shirazi Beheshtih. Modafinil-coated nanoparticle increases expressions of brain-derived neurotrophic factor, glial cell line-derived neurotrophic factor and neuronal nuclear protein, and protects against middle cerebral artery occlusion-induced neuron apoptosis in the rat hippocampus. Anatomical record (Hoboken, N.J. : 2007). vol 304. issue 9. 2021-09-03. PMID:33345406. |
modafinil-coated nanoparticle increases expressions of brain-derived neurotrophic factor, glial cell line-derived neurotrophic factor and neuronal nuclear protein, and protects against middle cerebral artery occlusion-induced neuron apoptosis in the rat hippocampus. |
2021-09-03 |
2023-08-13 |
human |