| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sathish Venkataramanappa, Dagmar Schütz, Friederike Saaber, Praveen Ashok Kumar, Philipp Abe, Stefan Schulz, Ralf Stum. The microcephaly gene Donson is essential for progenitors of cortical glutamatergic and GABAergic neurons. PLoS genetics. vol 17. issue 3. 2021-08-02. PMID:33739968. |
emx1-cre-mediated donson deletion in progenitors of cortical glutamatergic neurons caused extensive apoptosis in the early dorsomedial neuroepithelium, thus preventing formation of the neocortex and hippocampus. |
2021-08-02 |
2023-08-13 |
mouse |
| Dae-Myung Ju. Editorial Expression of Concern: Baicalein protects HT22 murine hippocampal neuronal cells against endoplasmic reticulum stress-induced apoptosis through inhibition of reactive oxygen species production and CHOP induction. Experimental & molecular medicine. vol 53. issue 4. 2021-07-31. PMID:33864027. |
editorial expression of concern: baicalein protects ht22 murine hippocampal neuronal cells against endoplasmic reticulum stress-induced apoptosis through inhibition of reactive oxygen species production and chop induction. |
2021-07-31 |
2023-08-13 |
Not clear |
| Xing Liu, Jiefeng Geng, Haiming Guo, Huaping Zhao, Yanqiu A. Propofol inhibited apoptosis of hippocampal neurons in status epilepticus through miR-15a-5p/NR2B/ERK1/2 pathway. Cell cycle (Georgetown, Tex.). vol 19. issue 9. 2021-07-30. PMID:32212891. |
propofol inhibited apoptosis of hippocampal neurons in status epilepticus through mir-15a-5p/nr2b/erk1/2 pathway. |
2021-07-30 |
2023-08-13 |
rat |
| Xing Liu, Jiefeng Geng, Haiming Guo, Huaping Zhao, Yanqiu A. Propofol inhibited apoptosis of hippocampal neurons in status epilepticus through miR-15a-5p/NR2B/ERK1/2 pathway. Cell cycle (Georgetown, Tex.). vol 19. issue 9. 2021-07-30. PMID:32212891. |
the interaction between mir-15a-5p and nr2b was assessed using a luciferase reporter assay.propofol inhibited cell apoptosis and increased mir-15a-5p expression both in hippocampal tissues of se rats and low mg |
2021-07-30 |
2023-08-13 |
rat |
| Xinzhao Chen, Yifan Jiang, Jiayu Wang, Yishu Liu, Menglei Xiao, Congshan Song, Yu Bai, Nancy Yinuo Han, Fang Ha. Synapse impairment associated with enhanced apoptosis in post-traumatic stress disorder. Synapse (New York, N.Y.). vol 74. issue 2. 2021-07-29. PMID:31562782. |
synapse impairment is associated with post-traumatic stress disorder (ptsd), which is characterized by enhanced apoptosis in the hippocampus, amygdala, and other brain regions. |
2021-07-29 |
2023-08-13 |
Not clear |
| Yilong Wang, Xiaohu An, Xiaoqing Zhang, Jianhui Liu, Jianwei Wang, Zeyong Yan. Lithium chloride ameliorates cognition dysfunction induced by sevoflurane anesthesia in rats. FEBS open bio. vol 10. issue 2. 2021-07-28. PMID:31867790. |
we report that anesthesia with sev significantly impaired memory performance, induced oxidative stress and hippocampal neuron apoptosis, and stimulated gsk-3β activity. |
2021-07-28 |
2023-08-13 |
rat |
| Yilong Wang, Xiaohu An, Xiaoqing Zhang, Jianhui Liu, Jianwei Wang, Zeyong Yan. Lithium chloride ameliorates cognition dysfunction induced by sevoflurane anesthesia in rats. FEBS open bio. vol 10. issue 2. 2021-07-28. PMID:31867790. |
in addition, licl reduced hippocampal neuron apoptosis and oxidative stress induced by sev anesthesia. |
2021-07-28 |
2023-08-13 |
rat |
| Ye Li, Cuiqin Fan, Rui Gao, Tian Lan, Wenjing Wang, Shu Yan Y. Hippocampal miR-211-5p regulates neurogenesis and depression-like behaviors in the rat. Neuropharmacology. vol 194. 2021-07-28. PMID:34062164. |
taken together, the results of our study reveal that altered levels of mir-211-5p in the hippocampal dg area exert a significant impact on neurogenesis, apoptosis and thus depression-like behaviors in rats. |
2021-07-28 |
2023-08-13 |
rat |
| Xudan Liu, Yao Chen, Huanhuan Wang, Yuting Wei, Ye Yuan, Qianqian Zhou, Fang Fang, Sainan Shi, Xiaojing Jiang, Yinqiao Dong, Xin L. Microglia-derived IL-1β promoted neuronal apoptosis through ER stress-mediated signaling pathway PERK/eIF2α/ATF4/CHOP upon arsenic exposure. Journal of hazardous materials. vol 417. 2021-07-28. PMID:34229406. |
microglia-derived il-1β promoted hippocampal neuronal apoptosis through er stress-mediated perk/eif2α/atf4/chop apoptotic pathway. |
2021-07-28 |
2023-08-13 |
Not clear |
| Mary E Dail, Meghan L M Brino, Janice E Chamber. Effects of novel brain-penetrating oxime acetylcholinesterase reactivators on sarin surrogate-induced changes in rat brain gene expression. Journal of biochemical and molecular toxicology. vol 35. issue 6. 2021-07-27. PMID:33682265. |
the hippocampus was examined via quantitative polymerase chain reaction for the expression of immediate-early genes involved in brain repair (bdnf), increasing neurotoxicity (fos), and apoptosis control (jdp2, bcl2l1, bcl2l11). |
2021-07-27 |
2023-08-13 |
rat |
| Xiaolin Wu, Yingjuan Liu, Lin Zhu, Yue Wang, Yuqian Ren, Baohe Cheng, Leiming Ren, Keli Ge, Hongyun L. Cerebroprotein Hydrolysate-I Inhibits Hippocampal Neuronal Apoptosis by Activating PI3K/Akt Signaling Pathway in Vascular Dementia Mice. Neuropsychiatric disease and treatment. vol 17. 2021-07-27. PMID:34305399. |
cerebroprotein hydrolysate-i inhibits hippocampal neuronal apoptosis by activating pi3k/akt signaling pathway in vascular dementia mice. |
2021-07-27 |
2023-08-13 |
mouse |
| Hao Zhu, Yu Yang, Min Zhu, Xiao Shi, Le Ye, Song Zhang, Hongwei Fang, Wenjuan Y. Alteration in the expression of inflammatory cytokines in primary hippocampal astrocytes in response to MK-801 through ERK1/2 and PI3K signals. Cytokine. vol 138. 2021-07-26. PMID:33187817. |
mk-801 treatment did not induce hippocampal astrocytes apoptosis or proliferation, however, mk-801 enhanced astrocytes viability. |
2021-07-26 |
2023-08-13 |
rat |
| Yu Xiao, Ying Dai, Li Li, Fang Geng, Yisha Xu, Jinqiu Wang, Shu Wang, Junning Zha. Tetrahydrocurcumin ameliorates Alzheimer's pathological phenotypes by inhibition of microglial cell cycle arrest and apoptosis via Ras/ERK signaling. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 139. 2021-07-26. PMID:34243602. |
by proteomic analysis of the hippocampus of mice, 157 differentially expressed proteins were identified in app/ps1 mice treated with thc (comparing with app/ps1 mice), which also suggested that the effects of thc on the cell cycle and apoptosis were mostly related to the "ras signaling pathway", etc. |
2021-07-26 |
2023-08-13 |
mouse |
| Ji Yun Baek, Kiwon Jung, Young-Mi Kim, Hyun-Young Kim, Ki Sung Kang, Young-Won Chi. Protective Effect of γ-mangostin Isolated from the Peel of Biomolecules. vol 11. issue 2. 2021-07-23. PMID:33514017. |
to investigate the effect of γ-mangostin on apoptosis, 5 mm of glutamate was used to induce apoptotic cell death in mouse hippocampal ht22 cells. |
2021-07-23 |
2023-08-13 |
mouse |
| Meiyue Wang, Yong Zuo, Xincheng Li, Yan Li, Anand Thirupathi, Peng Yu, Guofen Gao, Changhao Zhou, Yanzhong Chang, Zhenhua Sh. Effect of sevoflurane on iron homeostasis and toxicity in the brain of mice. Brain research. vol 1757. 2021-07-23. PMID:33539795. |
changes in the ratio of bcl2/bax and tau/p-tau intensified the cell apoptosis in hippocampus and cortex tissues. |
2021-07-23 |
2023-08-13 |
mouse |
| Xiao-Chen Yu, Zhen Li, Xin-Ran Liu, Jia-Ni Hu, Rui Liu, Na Zhu, Yong L. The Antioxidant Effects of Whey Protein Peptide on Learning and Memory Improvement in Aging Mice Models. Nutrients. vol 13. issue 6. 2021-07-23. PMID:34205338. |
its specific mechanism may be related to reducing the degeneration of hippocampal nerve cells, reducing the apoptosis of nerve cells, improving the activity of ache, reducing the expression of inflammatory factors (tnf-α and il-1β) in brain tissue, reducing oxidative stress injury, and improving the expression of p-camkⅡ and bdnf synaptic plasticity protein. |
2021-07-23 |
2023-08-13 |
mouse |
| Matthias Deutsch, Carina Stegmayr, Sabine Balfanz, Arnd Bauman. Loss of HCN2 in Dorsal Hippocampus of Young Adult Mice Induces Specific Apoptosis of the CA1 Pyramidal Neuron Layer. International journal of molecular sciences. vol 22. issue 13. 2021-07-23. PMID:34206649. |
loss of hcn2 in dorsal hippocampus of young adult mice induces specific apoptosis of the ca1 pyramidal neuron layer. |
2021-07-23 |
2023-08-13 |
mouse |
| Wei Chen, Lingfei Jiang, Yueqiang Hu, Nong Tang, Ni Liang, Xing-Feng Li, Ye-Wen Chen, Hongling Qin, Lin W. Ferritin reduction is essential for cerebral ischemia-induced hippocampal neuronal death through p53/SLC7A11-mediated ferroptosis. Brain research. vol 1752. 2021-07-22. PMID:33333054. |
pathogenic changes, impaired viability, increased apoptosis, and elevated caspase-9 cleavage in hippocampal neurons were clearly recovered by ferritin. |
2021-07-22 |
2023-08-13 |
rat |
| Ting Dong, Ming-Cai Wu, Lu-Lu Tang, Hai-Lin Jiang, Ping Zhou, Chun-Jun Kuang, Li-Wei Tian, Wen-Ming Yan. GanDouLing promotes proliferation and differentiation of neural stem cells in the mouse model of Wilson's disease. Bioscience reports. vol 41. issue 1. 2021-07-21. PMID:33300046. |
in vivo assays confirmed that gdl increased the ratio of ki67+, tuj1+, and map2+ cells and suppressed apoptosis in the hippocampal region in wd mice. |
2021-07-21 |
2023-08-13 |
mouse |
| Yanan Shen, Lihai Chen, Yuan Zhang, Jiayue Du, Jing Hu, Hongguang Bao, Yan Xing, Yanna S. Phosphatase and Tensin Homolog Deleted on Chromosome Ten Knockdown Attenuates Cognitive Deficits by Inhibiting Neuroinflammation in a Mouse Model of Perioperative Neurocognitive Disorder. Neuroscience. vol 468. 2021-07-21. PMID:34166762. |
surgically treated mice had increased expression of pten, ampk, bax, il-1β, and tnf-α, as well as increasing number of activated microglia and apoptosis neurons in the hippocampus. |
2021-07-21 |
2023-08-13 |
mouse |