| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stefanie Klenke, Christian Specking, Maike Stegen, Andrea Engler, Jürgen Peter. Methylation in HT22 cells and primary hippocampal neurons with and without isoflurane exposurewhether isoflurane causes. BMC anesthesiology. vol 20. issue 1. 2021-07-05. PMID:32171245. |
while isoflurane anesthesia can evoke neuroinflammation and neuroapoptosis in young animals, we investigated in a permanent hippocampal cell line (ht22) and in primary hippocampal neurons in an a priori in vitro analysis, whether isoflurane exposure 1) evokes dna methylation changes in genes involved in apoptosis and inflammation, and 2) results observed in a permanent hippocampal cell line are comparable to primary hippocampal neurons. |
2021-07-05 |
2023-08-13 |
Not clear |
| Zhenshu Li, Dezheng Zhou, Dalong Zhang, Jing Zhao, Wen Li, Yue Sun, Yongjie Chen, Huan Liu, John X Wilson, Zhiyong Qian, Guowei Huan. Folic Acid Inhibits Aging-Induced Telomere Attrition and Apoptosis in Astrocytes In Vivo and In Vitro. Cerebral cortex (New York, N.Y. : 1991). 2021-07-05. PMID:34223882. |
the results showed that fa supplementation inhibited aging-induced astrocytosis, astrocyte apoptosis, neurodegeneration, and prevented telomere attrition in hippocampus and cortex of samp8 mice. |
2021-07-05 |
2023-08-13 |
mouse |
| Shu Ye, Dao-Jun Xie, Peng Zhou, Hua-Wu Gao, Meng-Ting Zhang, Da-Bao Chen, Yun-Peng Qin, Xin Lei, Xin-Quan Li, Juan Liu, Ya-Xun Cheng, Yong-Chuan Yao, Biao Cai, Guo-Ming She. Huang-Pu-Tong-Qiao Formula Ameliorates the Hippocampus Apoptosis in Diabetic Cognitive Dysfunction Mice by Activating CREB/BDNF/TrkB Signaling Pathway. Evidence-based complementary and alternative medicine : eCAM. vol 2021. 2021-07-03. PMID:34211563. |
huang-pu-tong-qiao formula ameliorates the hippocampus apoptosis in diabetic cognitive dysfunction mice by activating creb/bdnf/trkb signaling pathway. |
2021-07-03 |
2023-08-13 |
mouse |
| Yanqiu Jia, Zhe Li, Tianjun Wang, Mingyue Fan, Jiaxi Song, Peiyuan Lv, Wei Ji. Shikonin Attenuates Chronic Cerebral Hypoperfusion-Induced Cognitive Impairment by Inhibiting Apoptosis via PTEN/Akt/CREB/BDNF Signaling. Evidence-based complementary and alternative medicine : eCAM. vol 2021. 2021-07-03. PMID:34211568. |
the effects of sk treatment on the pten/akt/creb/bdnf signaling pathway and apoptosis in hippocampal neurons were examined in a rat model of vad established via bilateral common carotid artery occlusion (bccao). |
2021-07-03 |
2023-08-13 |
rat |
| Yanqiu Jia, Zhe Li, Tianjun Wang, Mingyue Fan, Jiaxi Song, Peiyuan Lv, Wei Ji. Shikonin Attenuates Chronic Cerebral Hypoperfusion-Induced Cognitive Impairment by Inhibiting Apoptosis via PTEN/Akt/CREB/BDNF Signaling. Evidence-based complementary and alternative medicine : eCAM. vol 2021. 2021-07-03. PMID:34211568. |
in conclusion, sk inhibited hippocampal neuronal apoptosis to protect against cch-induced injury by regulating the pten/akt/creb/bdnf signaling pathway, consequently improving cognitive impairment. |
2021-07-03 |
2023-08-13 |
rat |
| Xiaojie Zhang, Xueling Guo, Xiaoxuan Kang, Hui Yang, Weiyi Guo, Lingmei Guan, Hai Wu, Libo D. Surface Functionalization of Pegylated Gold Nanoparticles with Antioxidants Suppresses Nanoparticle-Induced Oxidative Stress and Neurotoxicity. Chemical research in toxicology. vol 33. issue 5. 2021-07-02. PMID:32125152. |
more importantly, both the apoptosis of neurons and the activation of astrocytes were observed in the hippocampus of mice injected with au@peg. |
2021-07-02 |
2023-08-13 |
mouse |
| Yang Zhang, Xiao-Bo Zhu, Jin-Chuan Zhao, Xian-Feng Gao, Xiao-Na Zhang, Kun Ho. Neuroprotective effect of resveratrol against radiation after surgically induced brain injury by reducing oxidative stress, inflammation, and apoptosis through NRf2/HO-1/NF-κB signaling pathway. Journal of biochemical and molecular toxicology. vol 34. issue 12. 2021-07-02. PMID:32815255. |
also, an apoptosis marker, caspase-3-positive cells, was seen in the hippocampus. |
2021-07-02 |
2023-08-13 |
rat |
| Weiying Sun, Jun Zhao, Chunzhi L. Dexmedetomidine Provides Protection Against Hippocampal Neuron Apoptosis and Cognitive Impairment in Mice with Alzheimer's Disease by Mediating the miR-129/YAP1/JAG1 Axis. Molecular neurobiology. vol 57. issue 12. 2021-07-01. PMID:32839917. |
dexmedetomidine provides protection against hippocampal neuron apoptosis and cognitive impairment in mice with alzheimer's disease by mediating the mir-129/yap1/jag1 axis. |
2021-07-01 |
2023-08-13 |
mouse |
| Li Cao, Yunjing Jiang, Lei Zhu, Wei Xu, Xiaoyan Chu, Yafei Zhang, Sajid Ur Rahman, Shibin Feng, Yu Li, Jinjie Wu, Xichun Wan. Deoxynivalenol Induces Caspase-8-Mediated Apoptosis through the Mitochondrial Pathway in Hippocampal Nerve Cells of Piglet. Toxins. vol 13. issue 2. 2021-07-01. PMID:33498252. |
deoxynivalenol induces caspase-8-mediated apoptosis through the mitochondrial pathway in hippocampal nerve cells of piglet. |
2021-07-01 |
2023-08-13 |
Not clear |
| Li Cao, Yunjing Jiang, Lei Zhu, Wei Xu, Xiaoyan Chu, Yafei Zhang, Sajid Ur Rahman, Shibin Feng, Yu Li, Jinjie Wu, Xichun Wan. Deoxynivalenol Induces Caspase-8-Mediated Apoptosis through the Mitochondrial Pathway in Hippocampal Nerve Cells of Piglet. Toxins. vol 13. issue 2. 2021-07-01. PMID:33498252. |
using piglet hippocampal nerve cells (phncs), we evaluated the effects of different concentrations of don on typical indicators of apoptosis. |
2021-07-01 |
2023-08-13 |
Not clear |
| Meng-Yuan Diao, Jinhao Zheng, Yi Shan, Shaosong Xi, Ying Zhu, Wei Hu, Zhaofen Li. Hypothermia prevents hippocampal oxidative stress and apoptosis via the GSK-3β/Nrf2/HO-1 signaling pathway in a rat model of cardiac arrest-induced brain damage. Neurological research. vol 42. issue 9. 2021-06-30. PMID:32529954. |
hypothermia prevents hippocampal oxidative stress and apoptosis via the gsk-3β/nrf2/ho-1 signaling pathway in a rat model of cardiac arrest-induced brain damage. |
2021-06-30 |
2023-08-13 |
rat |
| Mohammad Fazelzadeh, Mohammad Esmaeil Afzalpour, Ziya Fallah Mohammadi, Hossein Falah Mohammad. The effects of voluntary complex and regular wheel running exercises on the levels of 8-oxoguanine DNA glycosylase, semaphorin 3B, H2O2, and apoptosis in the hippocampus of diabetic rats. Brain and behavior. vol 11. issue 3. 2021-06-30. PMID:33471970. |
the effects of voluntary complex and regular wheel running exercises on the levels of 8-oxoguanine dna glycosylase, semaphorin 3b, h2o2, and apoptosis in the hippocampus of diabetic rats. |
2021-06-30 |
2023-08-13 |
rat |
| Retraction. Journal of cellular physiology. 2021-06-30. PMID:34191275. |
retraction: "effects of microrna-10a on synapse remodeling in hippocampal neurons and neuronal cell proliferation and apoptosis through the bdnf-trkb signaling pathway in a rat model of alzheimer's disease," by bo-wen wu, mi-shan wu, jin-dong guo, j cell physiol. |
2021-06-30 |
2023-08-13 |
rat |
| Retraction. Journal of cellular physiology. 2021-06-30. PMID:34191281. |
retraction: "microrna-421 suppresses the apoptosis and autophagy of hippocampal neurons in epilepsy mice model by inhibition of the tlr/myd88 pathway," by xin wen, xin-rui han, yong-jian wang, shan wang, min shen, zi-feng zhang, shao-hua fan, qun shan, liang wang, meng-qiu li, bin hu, chun-hui sun, dong-mei wu, jun lu, yuan-lin zheng, j cell physiol. |
2021-06-30 |
2023-08-13 |
mouse |
| Retraction. Journal of cellular physiology. 2021-06-30. PMID:34191282. |
retraction: "downregulation of long noncoding rna h19 rescues hippocampal neurons from apoptosis and oxidative stress by inhibiting igf2 methylation in mice with streptozotocin-induced diabetes mellitus," by jin-lu yu, chao li, li-he che, yu-hao zhao, and yun-bao guo, j cell physiol. |
2021-06-30 |
2023-08-13 |
mouse |
| Retraction. Journal of cellular physiology. 2021-06-30. PMID:34191284. |
retraction: "effects of microrna-129 and its target gene c-fos on proliferation and apoptosis of hippocampal neurons in rats with epilepsy via the mapk signaling pathway," by dong-mei wu, yu-tong zhang, jun lu, yuan-lin zheng, j cell physiol. |
2021-06-30 |
2023-08-13 |
rat |
| Jing Wu, Zhen Fan, Yuxing Zhao, Qiunan Chen, Qian Xia. Inhibition of soluble epoxide hydrolase (sEH) protects hippocampal neurons and reduces cognitive decline in type 2 diabetic mice. The European journal of neuroscience. vol 53. issue 8. 2021-06-29. PMID:33595911. |
moreover, the seh inhibitor trans-4-[4-(3-adamantan-1-y1-ureido)-cyclohexyloxy]-benzoic acid (t-aucb) prevents cognitive dysfunction and decreased ros accumulation and apoptosis in the diabetic hippocampus. |
2021-06-29 |
2023-08-13 |
mouse |
| Hui Yao, Hui Shen, Hao Yu, Changliang Wang, Runtao Ding, Xinze Lan, Dilichati Tash, Xu Wu, Xiaolong Wang, Guohua Zhan. Chronic ethanol exposure induced depressive-like behavior in male C57BL/6 N mice by downregulating GluA1. Physiology & behavior. vol 234. 2021-06-25. PMID:33713693. |
we confirmed that 90- and 180-day ethanol exposure can lead to depressive-like mouse behavior, cell apoptosis, neuronal degeneration, a reduction in glua1 and brain-derived neurotrophic factor (bdnf) expression, and an increase in il-6 and il-1β in the mouse hippocampus. |
2021-06-25 |
2023-08-13 |
mouse |
| Chung-Min Tsai, Shwu-Fen Chang, Hsi Chan. Transcranial photobiomodulation attenuates pentylenetetrazole-induced status epilepticus in peripubertal rats. Journal of biophotonics. vol 13. issue 8. 2021-06-23. PMID:32362066. |
conclusively, tpbm attenuated ptz-induced seizures, se and mortality in peripubertal rats and reduced ptz-induced neuronal injury, apoptosis of pv-ins and preserved pv positive perisomatic inhibitory network in the hippocampus. |
2021-06-23 |
2023-08-13 |
rat |
| Run-Dong Ma, Gui-Juan Zhou, Miao Qu, Ji-Hong Yi, Ya-Ling Tang, Xiang-Yi Yang, Ya-Xiong Nie, Hong-Feng G. Corticosterone induces neurotoxicity in PC12 cells via disrupting autophagy flux mediated by AMPK/mTOR signaling. CNS neuroscience & therapeutics. vol 26. issue 2. 2021-06-22. PMID:31423743. |
our previous study indicated that chronic stress caused autophagy impairment and subsequent neuron apoptosis in hippocampus. |
2021-06-22 |
2023-08-13 |
Not clear |