| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sayan Ghosh, Sreetama Choudhury, Olivia Chowdhury, Sudeshna Mukherjee, Ankur Das, Arindam Sain, Payal Gupta, Arghya Adhikary, Sreya Chattopadhya. Inflammation-induced behavioral changes is driven by alterations in Nrf2-dependent apoptosis and autophagy in mouse hippocampus: Role of fluoxetine. Cellular signalling. vol 68. 2021-06-09. PMID:31881324. |
significant alterations in nrf2-dependent cellular redox status, coupled with altered autophagy and increased apoptosis were noticed in the hippocampus of lps-exposed mice. |
2021-06-09 |
2023-08-13 |
mouse |
| Wenbin Kang, Dihan Lu, Xiaoyu Yang, Wudi Ma, Xi Chen, Keyu Chen, Xuanxian Xu, Xue Zhou, Lihua Zhou, Xia Fen. Sevoflurane Induces Hippocampal Neuronal Apoptosis by Altering the Level of Neuropeptide Y in Neonatal Rats. Neurochemical research. vol 45. issue 9. 2021-06-08. PMID:32378074. |
sevoflurane induces hippocampal neuronal apoptosis by altering the level of neuropeptide y in neonatal rats. |
2021-06-08 |
2023-08-13 |
rat |
| Wenbin Kang, Dihan Lu, Xiaoyu Yang, Wudi Ma, Xi Chen, Keyu Chen, Xuanxian Xu, Xue Zhou, Lihua Zhou, Xia Fen. Sevoflurane Induces Hippocampal Neuronal Apoptosis by Altering the Level of Neuropeptide Y in Neonatal Rats. Neurochemical research. vol 45. issue 9. 2021-06-08. PMID:32378074. |
however, the effects of npy on sevoflurane-induced hippocampal neuronal apoptosis have not been investigated. |
2021-06-08 |
2023-08-13 |
rat |
| Wenbin Kang, Dihan Lu, Xiaoyu Yang, Wudi Ma, Xi Chen, Keyu Chen, Xuanxian Xu, Xue Zhou, Lihua Zhou, Xia Fen. Sevoflurane Induces Hippocampal Neuronal Apoptosis by Altering the Level of Neuropeptide Y in Neonatal Rats. Neurochemical research. vol 45. issue 9. 2021-06-08. PMID:32378074. |
furthermore, neuronal apoptosis assay was conducted via immunofluorescence staining of cleaved caspase-3 and flow cytometry after exogenous npy administration to pnd7 rats as well as cultured hippocampal neurons to elucidate the role of npy in sevoflurane-induced neurotoxicity. |
2021-06-08 |
2023-08-13 |
rat |
| Wenbin Kang, Dihan Lu, Xiaoyu Yang, Wudi Ma, Xi Chen, Keyu Chen, Xuanxian Xu, Xue Zhou, Lihua Zhou, Xia Fen. Sevoflurane Induces Hippocampal Neuronal Apoptosis by Altering the Level of Neuropeptide Y in Neonatal Rats. Neurochemical research. vol 45. issue 9. 2021-06-08. PMID:32378074. |
herein, our results showed that sevoflurane caused a significant decrease in npy expression, whereas exogenous npy supplementation could reduce sevoflurane-induced hippocampal neuronal apoptosis both in vivo and in vitro. |
2021-06-08 |
2023-08-13 |
rat |
| Zhijun He, Menghuan Wang, Qionghui Zhao, Xiaoqian Li, Pengan Liu, Bingyu Ren, Chong Wu, Xiubo Du, Nan Li, Qiong Li. Bis(ethylmaltolato)oxidovanadium (IV) mitigates neuronal apoptosis resulted from amyloid-beta induced endoplasmic reticulum stress through activating peroxisome proliferator-activated receptor γ. Journal of inorganic biochemistry. vol 208. 2021-06-08. PMID:32466853. |
moreover, by adopting gw9662 and salubrinal, the inhibitor of pparγ and hyperphosphorylated eukaryotic translation initiation factor 2α, respectively, we further confirmed that beov alleviated aβ-induced er stress and neuronal apoptosis in primary hippocampal neurons by activating pparγ. |
2021-06-08 |
2023-08-13 |
mouse |
| Dianxun Liu, Dongqing D. Mulberry Fruit Extract Alleviates Cognitive Impairment by Promoting the Clearance of Amyloid-β and Inhibiting Neuroinflammation in Alzheimer's Disease Mice. Neurochemical research. vol 45. issue 9. 2021-06-08. PMID:32488469. |
in histological, we observed that mfe reduced aβ plaques and neuron apoptosis both in the cortex and hippocampus tissues of app/ps1 mice. |
2021-06-08 |
2023-08-13 |
mouse |
| Guoying Lv, Chuangang Li, Weiwei Wang, Ning Li, Kai Wan. Silencing SP1 Alleviated Sevoflurane-Induced POCD Development via Cholinergic Anti-inflammatory Pathway. Neurochemical research. vol 45. issue 9. 2021-06-08. PMID:32594292. |
loss-of-function assay indicated that sp1 knockdown rescued the deactivation of cap and alleviated the sevoflurane-induced neuro-inflammation and apoptosis in rat hippocampus. |
2021-06-08 |
2023-08-13 |
rat |
| Guangchan Jing, Huanyuan Wang, Fengwei Nan, Yuqin Liu, Mengren Zhan. Naofucong Ameliorates High Glucose Induced Hippocampal Neuron Injury Through Suppressing P2X7/NLRP1/Caspase-1 Pathway. Frontiers in pharmacology. vol 12. 2021-06-08. PMID:34093185. |
naofucong decreased apoptosis, il-1β and il-18 levels in high glucose-induced ht22 hippocampal neuron cells. |
2021-06-08 |
2023-08-13 |
Not clear |
| Lili Xu, Qi Xu, Shaobing Dai, Cuicui Jiao, Yingying Tang, Jiaqian Xie, Hui Wu, Xinzhong Che. lncRNA Xist regulates sevoflurane-induced social and emotional impairment by modulating miR-98-5p/EDEM1 signaling axis in neonatal mice. Molecular therapy. Nucleic acids. vol 24. 2021-06-08. PMID:34094712. |
this study aimed to assess the role of lncrna xist in sevoflurane-induced social and emotional impairment and neuronal apoptosis in neonatal mice and hippocampal neuronal cells. |
2021-06-08 |
2023-08-13 |
mouse |
| Naomi Lomeli, Kaijun Di, Diana C Pearre, Tzu-Feng Chung, Daniela A Bot. Mitochondrial-associated impairments of temozolomide on neural stem/progenitor cells and hippocampal neurons. Mitochondrion. vol 52. 2021-06-07. PMID:32045717. |
longer tmz exposure impaired mitochondrial respiratory activity, increased oxidative stress, and induced apoptosis in hippocampal neurons. |
2021-06-07 |
2023-08-13 |
rat |
| Liujiu Tang, Xiang Ren, Ying Han, Le Chen, Xianyi Meng, Chenghong Zhang, Haiying Chu, Li Kong, Haiying M. Sulforaphane attenuates apoptosis of hippocampal neurons induced by high glucose via regulating endoplasmic reticulum. Neurochemistry international. vol 136. 2021-06-07. PMID:32199985. |
sulforaphane attenuates apoptosis of hippocampal neurons induced by high glucose via regulating endoplasmic reticulum. |
2021-06-07 |
2023-08-13 |
mouse |
| Liujiu Tang, Xiang Ren, Ying Han, Le Chen, Xianyi Meng, Chenghong Zhang, Haiying Chu, Li Kong, Haiying M. Sulforaphane attenuates apoptosis of hippocampal neurons induced by high glucose via regulating endoplasmic reticulum. Neurochemistry international. vol 136. 2021-06-07. PMID:32199985. |
we conclude that hg induced the development of endoplasmic reticulum stress (ers) in hippocampal neurons, eventually leading to the apoptosis of neurons. |
2021-06-07 |
2023-08-13 |
mouse |
| Liujiu Tang, Xiang Ren, Ying Han, Le Chen, Xianyi Meng, Chenghong Zhang, Haiying Chu, Li Kong, Haiying M. Sulforaphane attenuates apoptosis of hippocampal neurons induced by high glucose via regulating endoplasmic reticulum. Neurochemistry international. vol 136. 2021-06-07. PMID:32199985. |
sf prevented the ers and attenuates the hippocampal neuron apoptosis induced by hg both in vitro and in vivo. |
2021-06-07 |
2023-08-13 |
mouse |
| Haci Ömer Osmanlıoğlu, Mustafa Kemal Yıldırım, Yener Akyuva, Kenan Yıldızhan, Mustafa Nazıroğl. Morphine Induces Apoptosis, Inflammation, and Mitochondrial Oxidative Stress via Activation of TRPM2 Channel and Nitric Oxide Signaling Pathways in the Hippocampus. Molecular neurobiology. vol 57. issue 8. 2021-06-07. PMID:32524520. |
morphine induces apoptosis, inflammation, and mitochondrial oxidative stress via activation of trpm2 channel and nitric oxide signaling pathways in the hippocampus. |
2021-06-07 |
2023-08-13 |
Not clear |
| Yu Guo, Chenghong Zhang, Chunyang Wang, Yufei Huang, Jingyun Liu, Haiying Chu, Xiang Ren, Li Kong, Haiying M. Thioredoxin-1 Is a Target to Attenuate Alzheimer-Like Pathology in Diabetic Encephalopathy by Alleviating Endoplasmic Reticulum Stress and Oxidative Stress. Frontiers in physiology. vol 12. 2021-06-05. PMID:34079471. |
the immunocontent of the ad-related protein tau and the levels of cell apoptosis, β-amyloid (aβ) plaque formation and neuronal degeneration in the hippocampus of the diabetic group were increased. |
2021-06-05 |
2023-08-13 |
mouse |
| Peili Hu, Dan Wang, Yaru Zhang, Zixuan Cai, Ting Ye, Lijuan Tong, Xing Xu, Jiashu Lu, Fengguo Liu, Xu Lu, Chao Huan. Apoptosis-triggered decline in hippocampal microglia mediates adolescent intermittent alcohol exposure-induced depression-like behaviors in mice. Neuropharmacology. vol 170. 2021-06-03. PMID:32217088. |
we found that this aie-induced decline in hippocampal microglia was mediated by both microglial activation and apoptosis, as (i) 1 day of alcohol exposure induced a distinct activation of hippocampal microglia followed by their apoptosis, and (ii) blocking the initial activation of hippocampal microglia by pretreatment with minocycline suppressed the aie-induced apoptosis and loss of hippocampal microglia as well as the aie-induced depression-like symptoms. |
2021-06-03 |
2023-08-13 |
mouse |
| L L M Luijerink, A Vivekanandarajah, K A Waters, R Machaalan. The α7 and β2 nicotinic acetylcholine receptor subunits regulate apoptosis in the infant hippocampus, and in sudden infant death syndrome (SIDS). Apoptosis : an international journal on programmed cell death. vol 25. issue 7-8. 2021-06-03. PMID:32577853. |
the α7 and β2 nicotinic acetylcholine receptor subunits regulate apoptosis in the infant hippocampus, and in sudden infant death syndrome (sids). |
2021-06-03 |
2023-08-13 |
Not clear |
| L L M Luijerink, A Vivekanandarajah, K A Waters, R Machaalan. The α7 and β2 nicotinic acetylcholine receptor subunits regulate apoptosis in the infant hippocampus, and in sudden infant death syndrome (SIDS). Apoptosis : an international journal on programmed cell death. vol 25. issue 7-8. 2021-06-03. PMID:32577853. |
apoptosis is increased in the hippocampus of infants who died of sudden infant death syndrome (sids), yet it is not known via which mechanism this has occurred. |
2021-06-03 |
2023-08-13 |
Not clear |
| L L M Luijerink, A Vivekanandarajah, K A Waters, R Machaalan. The α7 and β2 nicotinic acetylcholine receptor subunits regulate apoptosis in the infant hippocampus, and in sudden infant death syndrome (SIDS). Apoptosis : an international journal on programmed cell death. vol 25. issue 7-8. 2021-06-03. PMID:32577853. |
our findings support the role of nachrs in regulating apoptosis in the sids hippocampus, and highlight the need for separate analysis according to risk factors. |
2021-06-03 |
2023-08-13 |
Not clear |