| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bingjie Yang, Guodong Luo, Chen Zhang, Luqiu Feng, Xianmei Luo, Ling Ga. Curcumin protects rat hippocampal neurons against pseudorabies virus by regulating the BDNF/TrkB pathway. Scientific reports. vol 10. issue 1. 2021-05-10. PMID:33335121. |
in the present study, for the first time, the protective effects of curcumin against prv-induced oxidative stress, apoptosis, and mitochondrial dysfunction in rat hippocampal neurons and the brain-derived neurotrophic factor (bdnf)/tropomyosin-related kinase b (trkb) pathway were investigated. |
2021-05-10 |
2023-08-13 |
rat |
| Chengqun Wei, Xiuzhi Xu, Hongyan Zhu, Xiuyan Zhang, Zhan Ga. Promotive role of microRNA‑150 in hippocampal neurons apoptosis in vascular dementia model rats. Molecular medicine reports. vol 23. issue 4. 2021-05-10. PMID:33576461. |
promotive role of microrna‑150 in hippocampal neurons apoptosis in vascular dementia model rats. |
2021-05-10 |
2023-08-13 |
rat |
| Ziwei Hu, Ke Hu, Rui Wang, Yueming Gu, Wei Ouyang, Junjie Zhou, Youliang We. Differentially expressed genes accompanying neurobehavioral deficits in a modified rat model of vascular dementia. Neuroscience letters. vol 750. 2021-05-10. PMID:33640362. |
erbb3, a gene mainly involved in cranial nervous system development, negative regulation of neuronal apoptosis, and signal transduction, was downregulated in the hippocampus of 2-vo rats compared to sham rats. |
2021-05-10 |
2023-08-13 |
rat |
| Hossein Khastar, Behzad Garmabi, Fatemeh Zare Mehrjerdi, Mohammad Taghi Rahimi, Nabi Shamsaei, Amir-Hossein Ali, Nilofar Khorsand, Mehdi Khaksar. Cyanocobalamin improves memory impairment via inhibition of necrosis and apoptosis of hippocampal cell death after transient global ischemia/reperfusion. Iranian journal of basic medical sciences. vol 24. issue 2. 2021-05-08. PMID:33953854. |
cyanocobalamin improves memory impairment via inhibition of necrosis and apoptosis of hippocampal cell death after transient global ischemia/reperfusion. |
2021-05-08 |
2023-08-13 |
rat |
| Xun-Hu Gu, Li-Jun Xu, Li-Li Zheng, Yuan-Jian Yang, Zhen-Yu Tang, Han-Jun Wu, Zhen-Zhen Chen, Wei Wan. Long non-coding RNA uc.80- overexpression promotes M2 polarization of microglias to ameliorate depression in rats. IUBMB life. vol 72. issue 10. 2021-04-30. PMID:32780551. |
uc.80- overexpression led to a decrease in apoptosis of hippocampal neurons in vivo and in vitro. |
2021-04-30 |
2023-08-13 |
rat |
| Eliana Cristina de Brito Toscano, Larissa Fonseca da Cunha Sousa, Graciela Kunrath Lima, Leonardo Antunes Mesquita, Márcia Carvalho Vilela, David Henrique Rodrigues, Rodrigo Novaes Ferreira, Frederico Marianetti Soriani, Marco Antônio Campos, Erna Geessien Kroon, Mauro Martins Teixeira, Aline Silva de Miranda, Milene Alvarenga Rachid, Antônio Lúcio Teixeir. Neuroinflammation is associated with reduced SOCS2 and SOCS3 expression during intracranial HSV-1 infection. Neuroscience letters. vol 736. 2021-04-30. PMID:32800922. |
the aim of the current study is to investigate the potential association between socs2, socs3, cytokines, and hippocampal damage, especially neuronal apoptosis, during acute intracranial hsv-1 infection in mice. |
2021-04-30 |
2023-08-13 |
mouse |
| Hongxuan Feng, Qian Gui, Guanhui Wu, Wei Zhu, Xiaofeng Dong, Mingqiang Shen, Xuetao Fu, Guomei Shi, Hailong Luo, Xiaoyan Yang, Shouru Xue, Qingzhang Chen. Long noncoding RNA Nespas inhibits apoptosis of epileptiform hippocampal neurons by inhibiting the PI3K/Akt/mTOR pathway. Experimental cell research. vol 398. issue 1. 2021-04-30. PMID:33212147. |
long noncoding rna nespas inhibits apoptosis of epileptiform hippocampal neurons by inhibiting the pi3k/akt/mtor pathway. |
2021-04-30 |
2023-08-13 |
Not clear |
| Hongxuan Feng, Qian Gui, Guanhui Wu, Wei Zhu, Xiaofeng Dong, Mingqiang Shen, Xuetao Fu, Guomei Shi, Hailong Luo, Xiaoyan Yang, Shouru Xue, Qingzhang Chen. Long noncoding RNA Nespas inhibits apoptosis of epileptiform hippocampal neurons by inhibiting the PI3K/Akt/mTOR pathway. Experimental cell research. vol 398. issue 1. 2021-04-30. PMID:33212147. |
furthermore, nespas promoted hippocampal neuron viability and proliferation, and inhibited hippocampal neuron apoptosis. |
2021-04-30 |
2023-08-13 |
Not clear |
| Hongxuan Feng, Qian Gui, Guanhui Wu, Wei Zhu, Xiaofeng Dong, Mingqiang Shen, Xuetao Fu, Guomei Shi, Hailong Luo, Xiaoyan Yang, Shouru Xue, Qingzhang Chen. Long noncoding RNA Nespas inhibits apoptosis of epileptiform hippocampal neurons by inhibiting the PI3K/Akt/mTOR pathway. Experimental cell research. vol 398. issue 1. 2021-04-30. PMID:33212147. |
in addition, rescue assays suggested that nespas promoted hippocampal neuron viability and proliferation, and suppressed hippocampal neuron apoptosis by upregulation of psmd11. |
2021-04-30 |
2023-08-13 |
Not clear |
| Hongxuan Feng, Qian Gui, Guanhui Wu, Wei Zhu, Xiaofeng Dong, Mingqiang Shen, Xuetao Fu, Guomei Shi, Hailong Luo, Xiaoyan Yang, Shouru Xue, Qingzhang Chen. Long noncoding RNA Nespas inhibits apoptosis of epileptiform hippocampal neurons by inhibiting the PI3K/Akt/mTOR pathway. Experimental cell research. vol 398. issue 1. 2021-04-30. PMID:33212147. |
our findings revealed that nespas suppressed the apoptosis of epileptiform hippocampal neurons by inhibiting the pi3k/akt/mtor pathway via upregulation of psmd11 at a mir-615-3p dependent way, indicating that nespas may offer a new direction for the treatment of epilepsy. |
2021-04-30 |
2023-08-13 |
Not clear |
| Jian Liu, Yuan-Shan Han, Lin Liu, Lin Tang, Hui Yang, Pan Meng, Hong-Qing Zhao, Yu-Hong Wan. Abnormal Glu/mGluR Neural regeneration research. vol 16. issue 4. 2021-04-29. PMID:33063735. |
abnormal glu/mglur our previous studies have shown that glutamate and hippocampal neuron apoptosis are key signals and direct factors associated with diabetes-related depression, and structural and functional damage to the hippocampal neurovascular unit has been associated with diabetes-related depression. |
2021-04-29 |
2023-08-13 |
Not clear |
| Pampa Saha, Sukanya Sarkar, Ramesh Kumar Paidi, Subhas C Biswa. TIMP-1: A key cytokine released from activated astrocytes protects neurons and ameliorates cognitive behaviours in a rodent model of Alzheimer's disease. Brain, behavior, and immunity. vol 87. 2021-04-27. PMID:32194232. |
in a well characterized aβ-infused rodent model of ad, intra-cerebroventricular administration of timp-1 revealed a reduction in aβ load and apoptosis in hippocampal and cortical regions. |
2021-04-27 |
2023-08-13 |
rat |
| Xiao W Mao, Nina C Nishiyama, Stephanie D Byrum, Seta Stanbouly, Tamako Jones, Jacob Holley, Vijayalakshmi Sridharan, Marjan Boerma, Alan J Tackett, Jeffrey S Willey, Michael J Pecaut, Michael D Del. Spaceflight induces oxidative damage to blood-brain barrier integrity in a mouse model. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 34. issue 11. 2021-04-27. PMID:32981077. |
quantitative assessment of brain tissue demonstrated that spaceflight caused an up to 2.2-fold increase in apoptosis in the hippocampus compared to the control group. |
2021-04-27 |
2023-08-13 |
mouse |
| Jun-Jie Tang, Shuang Feng, Xing-Dong Chen, Hua Huang, Min Mao, Hai-Yan Wang, Sen Li, Xiu-Min Lu, Yong-Tang Wan. The Effects of P75NTR on Learning Memory Mediated by Hippocampal Apoptosis and Synaptic Plasticity. Current pharmaceutical design. vol 27. issue 4. 2021-04-26. PMID:32938344. |
the effects of p75ntr on learning memory mediated by hippocampal apoptosis and synaptic plasticity. |
2021-04-26 |
2023-08-13 |
Not clear |
| Jun-Jie Tang, Shuang Feng, Xing-Dong Chen, Hua Huang, Min Mao, Hai-Yan Wang, Sen Li, Xiu-Min Lu, Yong-Tang Wan. The Effects of P75NTR on Learning Memory Mediated by Hippocampal Apoptosis and Synaptic Plasticity. Current pharmaceutical design. vol 27. issue 4. 2021-04-26. PMID:32938344. |
it can be inferred that p75ntr mediates apoptosis in the hippocampus and amygdale, which may affect learning and memory behavior. |
2021-04-26 |
2023-08-13 |
Not clear |
| Li Zhang, Dandan Li, Juan Zhang, Ping Yan, Xueqin Liu, Lei Wang, Ajab Khan, Zhizhen Liu, Jianbing Mu, Jun Xu, Bo Niu, Jun Xi. Excessive apoptosis and ROS induced by ethionine affect neural cell viability and differentiation. Acta biochimica et biophysica Sinica. vol 52. issue 10. 2021-04-26. PMID:33083831. |
we demonstrated that ethionine inhibited cell viability by disrupting the balance between proliferation and apoptosis, prevented nscs from differentiating into neurons and astrocytes, and blocked cell progression from g1 to s phase via reducing cyclin d1 function in nerve cells including nscs, a mouse hippocampal neuron cell line (ht-22), and a mouse brain neuroma cell line (neuro-2a). |
2021-04-26 |
2023-08-13 |
mouse |
| Md Sahab Uddin, Sharifa Hasana, Jamil Ahmad, Md Farhad Hossain, Md Mosiqur Rahman, Tapan Behl, Abdur Rauf, Ausaf Ahmad, Abdul Hafeez, Asma Perveen, Ghulam Md Ashra. Anti-Neuroinflammatory Potential of Polyphenols by Inhibiting NF-κB to Halt Alzheimer's Disease. Current pharmaceutical design. vol 27. issue 3. 2021-04-26. PMID:33213314. |
aβ can induce apoptosis, trigger an inflammatory response, and inhibit the synaptic plasticity of the hippocampus, which ultimately contributes to reducing cognitive functions and memory impairment. |
2021-04-26 |
2023-08-13 |
Not clear |
| Mingqian Ou, Weihao Fan, Furong Sun, Minhua Li, Meijun Lin, Yangsheng Yu, Shiyun Liang, Haojie Liao, Wanxin Jie, Yujie Cai, Feng Chen, Xiongjin Chen, Tian Zhao, Pei Tang, Lili Cui, Haihong Zho. Nasal Delivery of AntagomiR-741 Protects Against the Radiation-Induced Brain Injury in Mice. Radiation research. vol 195. issue 4. 2021-04-23. PMID:33544844. |
the delivery of antagomir-741 significantly reduced mir-741-3p levels in the hippocampus of rbi-modeled mice, and the cognitive dysfunction and neuronal apoptosis induced by radiation were also alleviated at 6 weeks postirradiation. |
2021-04-23 |
2023-08-13 |
mouse |
| J Jia, C Liu, Y Han, H Han, M Zhong, Y Ga. miR-146a alleviates the apoptosis of hippocampal neurons induced by microglia activation via targeting TRAF6. Human & experimental toxicology. vol 39. issue 12. 2021-04-22. PMID:32633138. |
mir-146a alleviates the apoptosis of hippocampal neurons induced by microglia activation via targeting traf6. |
2021-04-22 |
2023-08-13 |
Not clear |
| J Jia, C Liu, Y Han, H Han, M Zhong, Y Ga. miR-146a alleviates the apoptosis of hippocampal neurons induced by microglia activation via targeting TRAF6. Human & experimental toxicology. vol 39. issue 12. 2021-04-22. PMID:32633138. |
to identify the role of mir-146a and tumor necrosis factor receptor-associated factor 6 (traf6) for improving the apoptosis of hippocampal neurons induced by microglia activation. |
2021-04-22 |
2023-08-13 |
Not clear |