| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xueqin Yan, Zheng Gong, Rui Pan, Huili Wang, Haijie Tang, Hanyang He, Saixian Wen, Yongmei Fu, Jun Don. Synergistic Effect and Mechanism of Apoptosis Induction by Morphine and the HIV-1gp120V3 Loop in Hippocampal Neurons. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2021-04-01. PMID:33791922. |
we found that morphine and gp120v3 loop synergistically induced hippocampal neuron apoptosis, mediated by activating the extracellular signal-regulated kinase (erk) pathway, increasing the intracellular ca2 + concentration and expression of caspase-, and reducing the mitochondrial membrane potential. |
2021-04-01 |
2023-08-13 |
rat |
| Xueqin Yan, Zheng Gong, Rui Pan, Huili Wang, Haijie Tang, Hanyang He, Saixian Wen, Yongmei Fu, Jun Don. Synergistic Effect and Mechanism of Apoptosis Induction by Morphine and the HIV-1gp120V3 Loop in Hippocampal Neurons. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2021-04-01. PMID:33791922. |
these results indicate that erk plays a crucial role in the apoptosis of hippocampal neurons in hand. |
2021-04-01 |
2023-08-13 |
rat |
| Bin Zhang, Xiaojian Xu, Fei Niu, Xiang Mao, Jinqian Dong, Mengshi Yang, Fei Gao, Baiyun Li. Corticosterone Replacement Alleviates Hippocampal Neuronal Apoptosis and Spatial Memory Impairment Induced by Dexamethasone via Promoting Brain Corticosteroid Receptor Rebalance after Traumatic Brain Injury. Journal of neurotrauma. vol 37. issue 2. 2021-03-31. PMID:31436134. |
corticosterone replacement alleviates hippocampal neuronal apoptosis and spatial memory impairment induced by dexamethasone via promoting brain corticosteroid receptor rebalance after traumatic brain injury. |
2021-03-31 |
2023-08-13 |
rat |
| Bin Zhang, Xiaojian Xu, Fei Niu, Xiang Mao, Jinqian Dong, Mengshi Yang, Fei Gao, Baiyun Li. Corticosterone Replacement Alleviates Hippocampal Neuronal Apoptosis and Spatial Memory Impairment Induced by Dexamethasone via Promoting Brain Corticosteroid Receptor Rebalance after Traumatic Brain Injury. Journal of neurotrauma. vol 37. issue 2. 2021-03-31. PMID:31436134. |
we hypothesize that the imbalance of gr/mr expression and activation caused by injury and irrational use of dexamethasone (dex) aggravates post-traumatic hippocampal apoptosis and spatial memory dysfunction, but that restoration by refilling mr and inhibiting gr promotes the survival of neurons. |
2021-03-31 |
2023-08-13 |
rat |
| Bin Zhang, Xiaojian Xu, Fei Niu, Xiang Mao, Jinqian Dong, Mengshi Yang, Fei Gao, Baiyun Li. Corticosterone Replacement Alleviates Hippocampal Neuronal Apoptosis and Spatial Memory Impairment Induced by Dexamethasone via Promoting Brain Corticosteroid Receptor Rebalance after Traumatic Brain Injury. Journal of neurotrauma. vol 37. issue 2. 2021-03-31. PMID:31436134. |
using rat controlled cortical impact model, we examined the plasma corticosterone (cort), corticosteroid receptor expression, apoptosis, and cell loss in the hippocampus, and, accordingly, the spatial memory after tbi and gc treatment within 7 days. |
2021-03-31 |
2023-08-13 |
rat |
| Jie Liu, Benke Liu, Ping Yuan, Li Cheng, Hong Sun, Jianxiong Gui, Yanan Pan, Dishu Huang, Hengsheng Chen, Li Jian. Role of PKA/CREB/BDNF signaling in PM2.5-induced neurodevelopmental damage to the hippocampal neurons of rats. Ecotoxicology and environmental safety. vol 214. 2021-03-30. PMID:33640725. |
our results indicate that pm2.5 exposure exerts neurodevelopmental toxicity as indicated by lower viability, apoptosis, and synaptic damage in primary cultured hippocampal neurons, and that the pka/creb/bdnf pathways could play a vital role in pm2.5-mediated neurodevelopmental toxicity. |
2021-03-30 |
2023-08-13 |
rat |
| Dalia G Mostafa, Huda H Satt. Resolvin D1 Prevents the Impairment in the Retention Memory and Hippocampal Damage in Rats Fed a Corn Oil-Based High Fat Diet by Upregulation of Nrf2 and Downregulation and Inactivation of p Neurochemical research. vol 45. issue 7. 2021-03-29. PMID:32253649. |
resolvin d1 prevents the impairment in the retention memory and hippocampal damage in rats fed a corn oil-based high fat diet by upregulation of nrf2 and downregulation and inactivation of p this study investigated the effect of a high-fat diet rich in corn oil (co-hfd) on the memory retention and hippocampal oxidative stress, inflammation, and apoptosis in rats, and examined if the underlying mechanisms involve modulating resolvin d1 (rvd1) levels and activation of p |
2021-03-29 |
2023-08-13 |
rat |
| Abbas Mohammadipour, Mahmoud Abudayya. Hippocampal toxicity of metal base nanoparticles. Is there a relationship between nanoparticles and psychiatric disorders? Reviews on environmental health. 2021-03-26. PMID:33770832. |
after entering the hippocampus, they induce oxidative stress, neuro-inflammation, mitochondrial dysfunction, and gene expression alteration in hippocampal cells, which finally lead to neuronal apoptosis. |
2021-03-26 |
2023-08-13 |
Not clear |
| Xiaosheng Fan, Ming Xiao, Qinghai Zhang, Na Li, Peili B. miR-195-Sirt3 Axis Regulates Angiotensin II-Induced Hippocampal Apoptosis and Learning Impairment in Mice. Psychology research and behavior management. vol 12. 2021-03-24. PMID:31827339. |
mir-195-sirt3 axis regulates angiotensin ii-induced hippocampal apoptosis and learning impairment in mice. |
2021-03-24 |
2023-08-13 |
mouse |
| Xiaosheng Fan, Ming Xiao, Qinghai Zhang, Na Li, Peili B. miR-195-Sirt3 Axis Regulates Angiotensin II-Induced Hippocampal Apoptosis and Learning Impairment in Mice. Psychology research and behavior management. vol 12. 2021-03-24. PMID:31827339. |
therefore, this study aimed to investigate the effects of mir-195-sirt3 axis on angiotensin ii (ang ii)-induced hippocampal apoptosis and behavioral influence. |
2021-03-24 |
2023-08-13 |
mouse |
| Yi Xu, Kun Cao, Bing Guo, Jie Xiang, Yang-Ting Dong, Xiao-Lan Qi, Wen-Feng Yu, Yan Xiao, Zhi-Zhong Gua. Lowered levels of nicotinic acetylcholine receptors and elevated apoptosis in the hippocampus of brains from patients with type 2 diabetes mellitus and Aging. vol 12. issue 14. 2021-03-24. PMID:32701482. |
lowered levels of nicotinic acetylcholine receptors and elevated apoptosis in the hippocampus of brains from patients with type 2 diabetes mellitus and cognitive impairment caused by diabetes has been gradually recognized. |
2021-03-24 |
2023-08-13 |
Not clear |
| Erratum: miR-195-Sirt3 Axis Regulates Angiotensin II-Induced Hippocampal Apoptosis and Learning Impairment in Mice [Corrigendum]. Psychology research and behavior management. vol 14. 2021-03-24. PMID:33758559. |
erratum: mir-195-sirt3 axis regulates angiotensin ii-induced hippocampal apoptosis and learning impairment in mice [corrigendum]. |
2021-03-24 |
2023-08-13 |
mouse |
| A González-Maciel, R M Romero-Velázquez, A Alfaro-Rodríguez, P Sanchez Aparicio, R Reynoso-Roble. Prenatal exposure to oxcarbazepine increases hippocampal apoptosis in rat offspring. Journal of chemical neuroanatomy. vol 103. 2021-03-23. PMID:31794794. |
prenatal exposure to oxcarbazepine increases hippocampal apoptosis in rat offspring. |
2021-03-23 |
2023-08-13 |
rat |
| A González-Maciel, R M Romero-Velázquez, A Alfaro-Rodríguez, P Sanchez Aparicio, R Reynoso-Roble. Prenatal exposure to oxcarbazepine increases hippocampal apoptosis in rat offspring. Journal of chemical neuroanatomy. vol 103. 2021-03-23. PMID:31794794. |
apoptosis was detected at three postnatal ages using the tunel technique in the ca1, and ca3 regions of the hippocampus and in the dentate gyrus (dg); neurogenesis was assessed in the dg using an antibody against doublecortin. |
2021-03-23 |
2023-08-13 |
rat |
| Yuexia Ding, Wei Zhu, Wei Kong, Tuo Li, Peng Zou, Hongguang Che. Edaravone attenuates neuronal apoptosis in hippocampus of rat traumatic brain injury model via activation of BDNF/TrkB signaling pathway. Archives of medical science : AMS. vol 17. issue 2. 2021-03-23. PMID:33747286. |
edaravone attenuates neuronal apoptosis in hippocampus of rat traumatic brain injury model via activation of bdnf/trkb signaling pathway. |
2021-03-23 |
2023-08-13 |
rat |
| Chun-Hua Fu, Fang-Fang Lai, Sai Chen, Cai-Xia Yan, Bing-Hong Zhang, Cheng-Zhi Fang, Gao-Hua Wan. Silencing of long non-coding RNA CRNDE promotes autophagy and alleviates neonatal hypoxic-ischemic brain damage in rats. Molecular and cellular biochemistry. vol 472. issue 1-2. 2021-03-17. PMID:32632609. |
administration with crnde shrna-expressing lentiviruses alleviated pathological injury and apoptosis in rat hippocampus, decreased infarct volume, and improved behavior performance of rats subjected to hibd. |
2021-03-17 |
2023-08-13 |
rat |
| S Huan, J Jin, C-X Shi, T Li, Z Dai, X-J F. Overexpression of miR-146a inhibits the apoptosis of hippocampal neurons of rats with cerebral hemorrhage by regulating autophagy. Human & experimental toxicology. vol 39. issue 9. 2021-03-16. PMID:32090627. |
overexpression of mir-146a inhibits the apoptosis of hippocampal neurons of rats with cerebral hemorrhage by regulating autophagy. |
2021-03-16 |
2023-08-13 |
rat |
| S Huan, J Jin, C-X Shi, T Li, Z Dai, X-J F. Overexpression of miR-146a inhibits the apoptosis of hippocampal neurons of rats with cerebral hemorrhage by regulating autophagy. Human & experimental toxicology. vol 39. issue 9. 2021-03-16. PMID:32090627. |
the apoptosis of hippocampal neurons was measured by tunel assay. |
2021-03-16 |
2023-08-13 |
rat |
| Summya Rashid, Adil Farooq Wali, Shahzada Mudasir Rashid, Rana M Alsaffar, Ajaz Ahmad, Basit L Jan, Bilal Ahmad Paray, Saeed M A Alqahtani, Azher Arafah, Muneeb U Rehma. Zingerone Targets Status Epilepticus by Blocking Hippocampal Neurodegeneration via Regulation of Redox Imbalance, Inflammation and Apoptosis. Pharmaceuticals (Basel, Switzerland). vol 14. issue 2. 2021-03-16. PMID:33670383. |
zingerone targets status epilepticus by blocking hippocampal neurodegeneration via regulation of redox imbalance, inflammation and apoptosis. |
2021-03-16 |
2023-08-13 |
mouse |
| Summya Rashid, Adil Farooq Wali, Shahzada Mudasir Rashid, Rana M Alsaffar, Ajaz Ahmad, Basit L Jan, Bilal Ahmad Paray, Saeed M A Alqahtani, Azher Arafah, Muneeb U Rehma. Zingerone Targets Status Epilepticus by Blocking Hippocampal Neurodegeneration via Regulation of Redox Imbalance, Inflammation and Apoptosis. Pharmaceuticals (Basel, Switzerland). vol 14. issue 2. 2021-03-16. PMID:33670383. |
however, zingerone treatment downregulated caspase-3 and upregulated bcl-2, increasing cell survival and decreasing hippocampal neural death, deciphering involvement of apoptosis in se. |
2021-03-16 |
2023-08-13 |
mouse |