| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Huan, J Jin, C-X Shi, T Li, Z Dai, X-J F. Overexpression of miR-146a inhibits the apoptosis of hippocampal neurons of rats with cerebral hemorrhage by regulating autophagy. Human & experimental toxicology. vol 39. issue 9. 2021-03-16. PMID:32090627. |
the apoptosis of hippocampal neurons was measured by tunel assay. |
2021-03-16 |
2023-08-13 |
rat |
| Summya Rashid, Adil Farooq Wali, Shahzada Mudasir Rashid, Rana M Alsaffar, Ajaz Ahmad, Basit L Jan, Bilal Ahmad Paray, Saeed M A Alqahtani, Azher Arafah, Muneeb U Rehma. Zingerone Targets Status Epilepticus by Blocking Hippocampal Neurodegeneration via Regulation of Redox Imbalance, Inflammation and Apoptosis. Pharmaceuticals (Basel, Switzerland). vol 14. issue 2. 2021-03-16. PMID:33670383. |
zingerone targets status epilepticus by blocking hippocampal neurodegeneration via regulation of redox imbalance, inflammation and apoptosis. |
2021-03-16 |
2023-08-13 |
mouse |
| Summya Rashid, Adil Farooq Wali, Shahzada Mudasir Rashid, Rana M Alsaffar, Ajaz Ahmad, Basit L Jan, Bilal Ahmad Paray, Saeed M A Alqahtani, Azher Arafah, Muneeb U Rehma. Zingerone Targets Status Epilepticus by Blocking Hippocampal Neurodegeneration via Regulation of Redox Imbalance, Inflammation and Apoptosis. Pharmaceuticals (Basel, Switzerland). vol 14. issue 2. 2021-03-16. PMID:33670383. |
however, zingerone treatment downregulated caspase-3 and upregulated bcl-2, increasing cell survival and decreasing hippocampal neural death, deciphering involvement of apoptosis in se. |
2021-03-16 |
2023-08-13 |
mouse |
| Yue Huang, Xiaolong Mei, Weishi Jiang, Hui Zhao, Zhenyu Yan, Haixia Zhang, Ying Liu, Xia Hu, Jingyi Zhang, Wenshuo Peng, Jing Zhang, Qingling Qi, Naiyao Che. Mesenchymal Stem Cell-Conditioned Medium Protects Hippocampal Neurons From Radiation Damage by Suppressing Oxidative Stress and Apoptosis. Dose-response : a publication of International Hormesis Society. vol 19. issue 1. 2021-03-16. PMID:33716588. |
mesenchymal stem cell-conditioned medium protects hippocampal neurons from radiation damage by suppressing oxidative stress and apoptosis. |
2021-03-16 |
2023-08-13 |
Not clear |
| Yue Huang, Xiaolong Mei, Weishi Jiang, Hui Zhao, Zhenyu Yan, Haixia Zhang, Ying Liu, Xia Hu, Jingyi Zhang, Wenshuo Peng, Jing Zhang, Qingling Qi, Naiyao Che. Mesenchymal Stem Cell-Conditioned Medium Protects Hippocampal Neurons From Radiation Damage by Suppressing Oxidative Stress and Apoptosis. Dose-response : a publication of International Hormesis Society. vol 19. issue 1. 2021-03-16. PMID:33716588. |
to investigate the effects of mesenchymal stem cell-conditioned medium (msc-cm) on radiation-induced oxidative stress, survival and apoptosis in hippocampal neurons. |
2021-03-16 |
2023-08-13 |
Not clear |
| EXPRESSION OF CONCERN: 'MicroRNA-132 protects hippocampal neurons against oxygen-glucose deprivation induced apoptosis'. International journal of immunopathology and pharmacology. vol 35. 2021-03-12. PMID:33631975. |
expression of concern: 'microrna-132 protects hippocampal neurons against oxygen-glucose deprivation induced apoptosis'. |
2021-03-12 |
2023-08-13 |
Not clear |
| Juanxian Cheng, Yan Wu, Liping Chen, Ying Li, Fengjiao Liu, Jingyuan Shao, Minghe Huang, Ming Fan, Haitao W. Loss of O-GlcNAc transferase in neural stem cells impairs corticogenesis. Biochemical and biophysical research communications. vol 532. issue 4. 2021-03-11. PMID:32896380. |
here we report that the selective deletion of o-glcnac transferase (ogt) in neural stem cells (nscs) in mice led to a series of severe brain developmental deficits, including dramatic shrinkage of cortical and hippocampal histoarchitecture, widespread neuronal apoptosis, decrease in cell proliferation, induction of endoplasmic reticulum (er) stress, and inhibition of neuronal dendritic and axonal differentiation. |
2021-03-11 |
2023-08-13 |
mouse |
| Anna O Giarratana, Cynthia Zheng, Sahithi Reddi, Shavonne L Teng, David Berger, Derek Adler, Patrick Sullivan, Smita Thakker-Varia, Janet Alde. APOE4 genetic polymorphism results in impaired recovery in a repeated mild traumatic brain injury model and treatment with Bryostatin-1 improves outcomes. Scientific reports. vol 10. issue 1. 2021-03-11. PMID:33199792. |
relative to injured apoe3 tr mice, injured apoe4 tr mice had more inflammation, neurodegeneration, apoptosis, p-tau, and activated microglia and less total brain-derived neurotrophic factor (bdnf) in the cortex and/or hippocampus at 1 and/or 21 days post-injury. |
2021-03-11 |
2023-08-13 |
mouse |
| Ruisan Zhang, Yongcai Zheng, Fengrui Hu, Xin Meng, Bosen Lv, Kejing Lao, Xingchun Gao, Xiaohua Zhang, Xingchun Go. Effect of (m)VD-hemopressin against Aβ1-42-induced oxidative stress and apoptosis in mouse hippocampal neurons. Peptides. vol 124. 2021-03-10. PMID:31730791. |
effect of (m)vd-hemopressin against aβ1-42-induced oxidative stress and apoptosis in mouse hippocampal neurons. |
2021-03-10 |
2023-08-13 |
mouse |
| Xichun Wang, Xiaoyan Chu, Li Cao, Jie Zhao, Lei Zhu, Sajid Ur Rahman, Zhen Hu, Yafei Zhang, Shibin Feng, Yu Li, Jinjie W. The role and regulatory mechanism of autophagy in hippocampal nerve cells of piglet damaged by deoxynivalenol. Toxicology in vitro : an international journal published in association with BIBRA. vol 66. 2021-03-10. PMID:32229166. |
this study aimed to determine the effects of pi3k/akt/mtor pathway on don-induced autophagy of piglet hippocampal nerve cells (phncs), and the relationship between autophagy and apoptosis. |
2021-03-10 |
2023-08-13 |
Not clear |
| Tsong-Hai Lee, Jen-Tsung Yang, Jr-Rung Lin, Chaur-Jong Hu, Wen-Hai Chou, Ching-Po Lin, Nai-Fang Ch. Protective effects of ischemic preconditioning against neuronal apoptosis and dendritic injury in the hippocampus are age-dependent. Journal of neurochemistry. vol 155. issue 4. 2021-03-10. PMID:32314365. |
protective effects of ischemic preconditioning against neuronal apoptosis and dendritic injury in the hippocampus are age-dependent. |
2021-03-10 |
2023-08-13 |
Not clear |
| Tsong-Hai Lee, Jen-Tsung Yang, Jr-Rung Lin, Chaur-Jong Hu, Wen-Hai Chou, Ching-Po Lin, Nai-Fang Ch. Protective effects of ischemic preconditioning against neuronal apoptosis and dendritic injury in the hippocampus are age-dependent. Journal of neurochemistry. vol 155. issue 4. 2021-03-10. PMID:32314365. |
this study thus suggests an age-dependent protective effect of ischemic preconditioning against both neuronal apoptosis and dendritic injury in hippocampus after forebrain ischemia. |
2021-03-10 |
2023-08-13 |
Not clear |
| Jianyun Ge, Yulin Huang, Yi Zhang, Lin Liu, Tianyu Gu, Xu Liu, Lei Yao, Mengmeng Cai, Jiafeng Sun, Jie Son. Metformin Inhibits Propofol-Induced Apoptosis of Mouse Hippocampal Neurons HT-22 Through Downregulating Cav-1. Drug design, development and therapy. vol 14. 2021-03-10. PMID:32368014. |
metformin inhibits propofol-induced apoptosis of mouse hippocampal neurons ht-22 through downregulating cav-1. |
2021-03-10 |
2023-08-13 |
mouse |
| Vikki Houghton, Andrea Du Preez, Sophie Lefèvre-Arbogast, Chiara de Lucia, Dorrain Y Low, Mireia Urpi-Sarda, Silvie R Ruigrok, Barbara Altendorfer, Raúl González-Domínguez, Cristina Andres-Lacueva, Ludwig Aigner, Paul J Lucassen, Aniko Korosi, Cécilia Samieri, Claudine Manach, Sandrine Thure. Caffeine Compromises Proliferation of Human Hippocampal Progenitor Cells. Frontiers in cell and developmental biology. vol 8. 2021-03-10. PMID:33015033. |
immunocytochemistry was used to quantify hippocampal progenitor integrity (i.e., sox2- and nestin-positive cells), proliferation (i.e., ki67-positive cells), cell count (i.e., dapi-positive cells), and apoptosis (i.e., cc3-positive cells). |
2021-03-10 |
2023-08-13 |
human |
| Junhua Li, Guiyun Wu, Wen Song, Yafang Liu, Zhixiao Han, Zhiwen Shen, Yujuan L. Prophylactic Melatonin Treatment Ameliorated Propofol-Induced Cognitive Dysfunction in Aged Rats. Neurotoxicity research. vol 39. issue 2. 2021-03-10. PMID:33159663. |
moreover, mitochondrial function (including reactive oxygen species, mitochondrial membrane potential and atp levels) and apoptosis were detected in the regions of hippocampus (hip) and prefrontal cortex (pfc). |
2021-03-10 |
2023-08-13 |
rat |
| Chih-Hung Wang, Wei-Tien Chang, Chien-Hua Huang, Min-Shan Tsai, Shing-Hwa Liu, Wen-Jone Che. Cerebral Blood Flow-Guided Manipulation of Arterial Blood Pressure Attenuates Hippocampal Apoptosis After Asphyxia-Induced Cardiac Arrest in Rats. Journal of the American Heart Association. vol 9. issue 13. 2021-03-09. PMID:32552439. |
cerebral blood flow-guided manipulation of arterial blood pressure attenuates hippocampal apoptosis after asphyxia-induced cardiac arrest in rats. |
2021-03-09 |
2023-08-13 |
rat |
| Xing Chen, Kewei Liu, Zhenzhou Lin, Kaibin Huang, Suyue Pa. Knockout of Transient Receptor Potential Melastatin 4 Channel Mitigates Cerebral Edema and Neuronal Injury After Status Epilepticus in Mice. Journal of neuropathology and experimental neurology. vol 79. issue 12. 2021-03-05. PMID:33186453. |
moreover, trpm4 deficiency significantly mitigated neuronal loss, cellular necrosis and apoptosis in the hippocampus and piriform cortex and mitigated astrocytosis and microgliosis. |
2021-03-05 |
2023-08-13 |
mouse |
| Shan Lei, Pan Lu, Yang Lu, Juan Zheng, Weisong Li, Ning Wang, Hong Zhang, Rong Li, Kui Wang, Jieqiong Wen, Haidong Wei, Yuanyuan Zhang, Zhengguo Qiu, Jing Xu, Haixia Lv, Xinlin Chen, Yong Liu, Pengbo Zhan. Dexmedetomidine Alleviates Neurogenesis Damage Following Neonatal Midazolam Exposure in Rats through JNK and P38 MAPK Pathways. ACS chemical neuroscience. vol 11. issue 4. 2021-03-03. PMID:31999428. |
midazolam decreased cell proliferation and increased cell apoptosis in the subventricular zone (svz), the subgranular zone (sgz) of the hippocampus, and cultured nscs. |
2021-03-03 |
2023-08-13 |
rat |
| Qin Sun, Tingxin Li, Yamei Li, Lingling Wei, Min Zhang, Shaoping Den. Bactericidal/Permeability-Increasing Protein Improves Cognitive Impairment in Diabetic Mice Frontiers in physiology. vol 11. 2021-03-03. PMID:33643054. |
next, hippocampal tissue injury and cell apoptosis were examined by hematoxylin-eosin (he) and terminal deoxynucleotidyl transferase-mediated dutp-biotin nick end labeling (tunel) staining. |
2021-03-03 |
2023-08-13 |
mouse |
| Qin Sun, Tingxin Li, Yamei Li, Lingling Wei, Min Zhang, Shaoping Den. Bactericidal/Permeability-Increasing Protein Improves Cognitive Impairment in Diabetic Mice Frontiers in physiology. vol 11. 2021-03-03. PMID:33643054. |
hfd mice following lps treatment showed significantly increased serum levels of tumor necrosis factor-α (tnf-α), interleukin (il)-1β, and il-6, and expressions of bcl-2-associated x protein (bax) and aβ but decreased expression of bcl-2 in hippocampal tissues, as well as enhanced fasting blood glucose, plasma insulin, glucose tolerance, insulin tolerance, cell apoptosis, aggravated hippocampal tissue injury and, ultimately, cognitive impairment. |
2021-03-03 |
2023-08-13 |
mouse |