| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chenmeng Song, Yusen Zhang, Le Cheng, Luping Zhang, Xuemin Li, Mengqian Shi, Haifeng Zha. [Effects of resveratrol combined with soy isoflavones on apoptosis induced by oxidative stress in hippocampus of aging model rats]. Wei sheng yan jiu = Journal of hygiene research. vol 49. issue 6. 2021-01-11. PMID:33413768. |
[effects of resveratrol combined with soy isoflavones on apoptosis induced by oxidative stress in hippocampus of aging model rats]. |
2021-01-11 |
2023-08-13 |
rat |
| Jing Zhao, Ling He, Lingling Yi. lncRNA NEAT1 Binds to MiR-339-5p to Increase HOXA1 and Alleviate Ischemic Brain Damage in Neonatal Mice. Molecular therapy. Nucleic acids. vol 20. 2021-01-10. PMID:32163893. |
the overexpression or knockdown of long non-coding rna (lncrna) nuclear-enriched abundant transcript 1 (neat1) in hippocampal neurons was used to determine the effect of lncrna neat1 on the expression of mir-339-5p and homeobox a1 (hoxa1) and apoptosis. |
2021-01-10 |
2023-08-13 |
mouse |
| Narmin Mokarizadeh, Pouran Karimi, Marjan Erfani, Saeed Sadigh-Eteghad, Nazila Fathi Maroufi, Nadereh Rashtchizade. β-Lapachone attenuates cognitive impairment and neuroinflammation in beta-amyloid induced mouse model of Alzheimer's disease. International immunopharmacology. vol 81. 2021-01-06. PMID:32070922. |
β-lapachone (β-lap) is a natural activator of nad(p)h quinone oxidoreductase 1 (nqo1) which has antioxidant and anti-inflammatory properties.this study investigated the effect of β-lap administration on aβ-induced memory deficit, oxidative stress, neuroinflammation, and apoptosis cell death in the hippocampus. |
2021-01-06 |
2023-08-13 |
mouse |
| Sang Jin Kim, Min Jea Shin, Dae Won Kim, Hyeon Ji Yeo, Eun Ji Yeo, Yeon Joo Choi, Eun Jeong Sohn, Kyu Hyung Han, Jinseu Park, Keun Wook Lee, Jong Kook Park, Yong-Jun Cho, Duk-Soo Kim, Won Sik Eum, Soo Young Cho. Tat-Biliverdin Reductase A Exerts a Protective Role in Oxidative Stress-Induced Hippocampal Neuronal Cell Damage by Regulating the Apoptosis and MAPK Signaling. International journal of molecular sciences. vol 21. issue 8. 2021-01-05. PMID:32290442. |
tat-biliverdin reductase a exerts a protective role in oxidative stress-induced hippocampal neuronal cell damage by regulating the apoptosis and mapk signaling. |
2021-01-05 |
2023-08-13 |
Not clear |
| Oleg Vetrovoy, Kseniia Sarieva, Ekaterina Lomert, Peter Nimiritsky, Natalia Eschenko, Olga Galkina, Andrey Lyanguzov, Ekaterina Tyulkova, Elena Rybnikov. Pharmacological HIF1 Inhibition Eliminates Downregulation of the Pentose Phosphate Pathway and Prevents Neuronal Apoptosis in Rat Hippocampus Caused by Severe Hypoxia. Journal of molecular neuroscience : MN. vol 70. issue 5. 2021-01-04. PMID:31865524. |
pharmacological hif1 inhibition eliminates downregulation of the pentose phosphate pathway and prevents neuronal apoptosis in rat hippocampus caused by severe hypoxia. |
2021-01-04 |
2023-08-13 |
rat |
| Oleg Vetrovoy, Kseniia Sarieva, Ekaterina Lomert, Peter Nimiritsky, Natalia Eschenko, Olga Galkina, Andrey Lyanguzov, Ekaterina Tyulkova, Elena Rybnikov. Pharmacological HIF1 Inhibition Eliminates Downregulation of the Pentose Phosphate Pathway and Prevents Neuronal Apoptosis in Rat Hippocampus Caused by Severe Hypoxia. Journal of molecular neuroscience : MN. vol 70. issue 5. 2021-01-04. PMID:31865524. |
graphical abstract hif1-dependent down-regulation of the pentose phosphate pathway contributes to the hypoxia-induced oxidative stress and neuronal apoptosis in the rat hippocampus. |
2021-01-04 |
2023-08-13 |
rat |
| Sherif Mohamed Zaki, Waleed Ahmed Abd Algaleel, Reda Abdelnasser Imam, Ghada F Soliman, Fatma M Ghonei. Nano-curcumin versus curcumin in amelioration of deltamethrin-induced hippocampal damage. Histochemistry and cell biology. vol 154. issue 2. 2021-01-01. PMID:32227291. |
oxidative stress induced apoptosis of hippocampal neurons through increasing nrf2, gamma-glutamyl cysteine synthetase heavy subunit (gcs-hs) and light subunit (gcs-ls) and decreasing ache. |
2021-01-01 |
2023-08-13 |
rat |
| Sherif Mohamed Zaki, Waleed Ahmed Abd Algaleel, Reda Abdelnasser Imam, Ghada F Soliman, Fatma M Ghonei. Nano-curcumin versus curcumin in amelioration of deltamethrin-induced hippocampal damage. Histochemistry and cell biology. vol 154. issue 2. 2021-01-01. PMID:32227291. |
it exerts apoptosis of hippocampal neurons through increasing nrf2, hs-gcs, ls-gcs and decreasing ache. |
2021-01-01 |
2023-08-13 |
rat |
| Jing Wang, Yali Niu, Huaying Tao, Mina Xue, Chunxiao Wa. Knockdown of lncRNA TUG1 inhibits hippocampal neuronal apoptosis and participates in aerobic exercise-alleviated vascular cognitive impairment. Biological research. vol 53. issue 1. 2020-12-29. PMID:33213523. |
knockdown of lncrna tug1 inhibits hippocampal neuronal apoptosis and participates in aerobic exercise-alleviated vascular cognitive impairment. |
2020-12-29 |
2023-08-13 |
Not clear |
| Jianmei Tian, Yongjie Tai, Mengrao Shi, Chunxiu Zhao, Wenwen Xu, Xuhua Ge, Guoji Zh. Atorvastatin Relieves Cognitive Disorder After Sepsis Through Reverting Inflammatory Cytokines, Oxidative Stress, and Neuronal Apoptosis in Hippocampus. Cellular and molecular neurobiology. vol 40. issue 4. 2020-12-28. PMID:31696375. |
atorvastatin relieves cognitive disorder after sepsis through reverting inflammatory cytokines, oxidative stress, and neuronal apoptosis in hippocampus. |
2020-12-28 |
2023-08-13 |
mouse |
| Hongli Ma, Tao Jiang, Wenxin Tang, Zhi Ma, Kairui Pu, Fuxing Xu, Haiqing Chang, Ge Zhao, Wei Gao, Yansong Li, Qiang Wan. Transplantation of platelet-derived mitochondria alleviates cognitive impairment and mitochondrial dysfunction in db/db mice. Clinical science (London, England : 1979). vol 134. issue 16. 2020-12-28. PMID:32794577. |
importantly, one month following mito-plt transplantation, daci was alleviated in db/db mice and the effect was accompanied with increased mitochondrial number, restored mitochondrial function, attenuated oxidative stress and neuronal apoptosis, as well as decreased accumulation of aβ and tau in the hippocampus. |
2020-12-28 |
2023-08-13 |
mouse |
| Napatsorn Saiyasit, Titikorn Chunchai, Dillon Prus, Kanokphong Suparan, Pansa Pittayapong, Nattayaporn Apaijai, Wasana Pratchayasakul, Jirapas Sripetchwandee, Nipon Chattipakorn M D Ph D, Siriporn C Chattipakor. Gut dysbiosis develops before metabolic disturbance and cognitive decline in high-fat diet-induced obese condition. Nutrition (Burbank, Los Angeles County, Calif.). vol 69. 2020-12-23. PMID:31580986. |
therefore, the aim of this study was to test the hypothesis that gut dysbiosis, peripheral inflammation, and peripheral insulin resistance occur before the brain inflammatory response, hippocampal synaptic dysplasticity, oxidative stress, apoptosis, and cognitive impairment in hfd-fed rats. |
2020-12-23 |
2023-08-13 |
rat |
| Lingxue Meng, Jian Liu, Congcong Wang, Zedong Ouyang, Jiahua Kuang, Qihua Pang, Ruifang Fa. Sex-specific oxidative damage effects induced by BPA and its analogs on primary hippocampal neurons attenuated by EGCG. Chemosphere. vol 264. issue Pt 1. 2020-12-22. PMID:33007573. |
to investigate whether bpa and its analogs cause oxidative damage effects on primary hippocampal neurons of rats, reactive oxygen species (ros), malondialdehyde (mda), superoxide dismutase (sod), mitochondrial membrane potential (mmp), apoptosis and cell viability assays were conducted after hippocampal neurons exposure to different concentrations of bpa, bps, and bpb (1, 10, 100 nm and 1, 10, 100 μm). |
2020-12-22 |
2023-08-13 |
rat |
| Qing Tao, Xianhe Wang, Lei Liu, Yongsheng Ji, Qingli Luo, Jian Du, Li Yu, Jilong Shen, Deyong Ch. Toxoplasma gondii Chinese I genotype Wh6 strain infection induces tau phosphorylation via activating GSK3β and causes hippocampal neuron apoptosis. Acta tropica. vol 210. 2020-12-17. PMID:32492398. |
toxoplasma gondii chinese i genotype wh6 strain infection induces tau phosphorylation via activating gsk3β and causes hippocampal neuron apoptosis. |
2020-12-17 |
2023-08-13 |
mouse |
| Qing Tao, Xianhe Wang, Lei Liu, Yongsheng Ji, Qingli Luo, Jian Du, Li Yu, Jilong Shen, Deyong Ch. Toxoplasma gondii Chinese I genotype Wh6 strain infection induces tau phosphorylation via activating GSK3β and causes hippocampal neuron apoptosis. Acta tropica. vol 210. 2020-12-17. PMID:32492398. |
in all, our results indicated that tgctwh6 infection not only led to phosphorylation of tau via activating gsk3β but also promoted hippocampal neuron apoptosis. |
2020-12-17 |
2023-08-13 |
mouse |
| Linbao Wen, Jingwei Sun, Xionggao Chen, Ruili D. miR-135b-dependent downregulation of S100B promotes neural stem cell differentiation in a hypoxia/ischemia-induced cerebral palsy rat model. American journal of physiology. Cell physiology. vol 319. issue 6. 2020-12-15. PMID:32491925. |
mir-135b elevation or s100b silencing resulted in promoted nsc differentiation, alleviated brain injury, and inhibited nsc apoptosis in hippocampus tissues of cp rats. |
2020-12-15 |
2023-08-13 |
rat |
| Ola A Hussein, Asmaa Fathi Abdel Mola, Amal Rate. Tramadol administration induced hippocampal cells apoptosis, astrogliosis, and microgliosis in juvenile and adult male mice, histological and immunohistochemical study. Ultrastructural pathology. vol 44. issue 1. 2020-12-14. PMID:31924115. |
tramadol administration induced hippocampal cells apoptosis, astrogliosis, and microgliosis in juvenile and adult male mice, histological and immunohistochemical study. |
2020-12-14 |
2023-08-13 |
mouse |
| Leila Mohammadzadeh, Khalil Abnous, Bibi Marjan Razavi, Hossein Hosseinzade. Crocin-protected malathion-induced spatial memory deficits by inhibiting TAU protein hyperphosphorylation and antiapoptotic effects. Nutritional neuroscience. vol 23. issue 3. 2020-12-11. PMID:30789100. |
also, malathion-induced apoptosis in the hippocampus. |
2020-12-11 |
2023-08-13 |
rat |
| Izabela Bialuk, Magdalena Cieślińska, Oksana Kowalczuk, Tomasz A Bonda, Jacek Nikliński, Maria M Winnick. IL-6 deficiency attenuates p53 protein accumulation in aged male mouse hippocampus. Biogerontology. vol 21. issue 1. 2020-12-11. PMID:31598806. |
taken together, attenuated p53 protein build-up, absence of enhanced apoptosis, and transcriptional up-regulation of autophagy-associated genes imply that il-6 deficiency may protect hippocampus from age-related accumulation of cellular damages. |
2020-12-11 |
2023-08-13 |
mouse |
| Bin Zhang, Xueli Zhu, Liang Wang, Zonggang Hou, Shuyu Hao, Mengshi Yang, Fei Gao, Baiyun Li. Inadequate Expression and Activation of Mineralocorticoid Receptor Aggravates Spatial Memory Impairment after Traumatic Brain Injury. Neuroscience. vol 424. 2020-12-10. PMID:31734415. |
we hypothesized that inadequate mr expression and activation caused by tbi aggravates posttraumatic hippocampal apoptosis but that restoration by restoring mrs promotes the survival of neurons. |
2020-12-10 |
2023-08-13 |
rat |