| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bin Zhang, Xueli Zhu, Liang Wang, Zonggang Hou, Shuyu Hao, Mengshi Yang, Fei Gao, Baiyun Li. Inadequate Expression and Activation of Mineralocorticoid Receptor Aggravates Spatial Memory Impairment after Traumatic Brain Injury. Neuroscience. vol 424. 2020-12-10. PMID:31734415. |
using a rat controlled cortical impact model, we examined plasma corticosterone, mr expression and activation, neuronal apoptosis in the hippocampus, and spatial memory on day 3 after injury with and without fludrocortisone (1 mg/kg) treatment. |
2020-12-10 |
2023-08-13 |
rat |
| Etrat Hooshmandi, Maryam Moosavi, Hermann Katinger, Shima Sardab, Rasoul Ghasemi, Nader Maghsoud. Correction to: CEPO (carbamylated erythropoietin)-Fc protects hippocampal cells in culture against beta amyloid-induced apoptosis: considering Akt/GSK-3β and ERK signaling pathways. Molecular biology reports. vol 47. issue 12. 2020-12-09. PMID:32436043. |
correction to: cepo (carbamylated erythropoietin)-fc protects hippocampal cells in culture against beta amyloid-induced apoptosis: considering akt/gsk-3β and erk signaling pathways. |
2020-12-09 |
2023-08-13 |
Not clear |
| Jiao Xiao, Rumeng Yao, Bingtian Xu, Huizhen Wen, Jiahong Zhong, Dan Li, Zhongzhen Zhou, Jiangping Xu, Haitao Wan. Inhibition of PDE4 Attenuates TNF-α-Triggered Cell Death Through Suppressing NF-κB and JNK Activation in HT-22 Neuronal Cells. Cellular and molecular neurobiology. vol 40. issue 3. 2020-12-07. PMID:31659561. |
in this study, we investigated the protective effects of fcpr16, a novel pde4 inhibitor, against tnf-α-induced cellular apoptosis in ht-22 hippocampal neuronal cells. |
2020-12-07 |
2023-08-13 |
Not clear |
| Mansoureh Eslami, Leila Alizadeh, Parastoo Morteza-Zadeh, Mohammad Sayya. The effect of Lipopolysaccharide (LPS) pretreatment on hippocampal apoptosis in traumatic rats. Neurological research. vol 42. issue 2. 2020-12-07. PMID:31914902. |
the effect of lipopolysaccharide (lps) pretreatment on hippocampal apoptosis in traumatic rats. |
2020-12-07 |
2023-08-13 |
rat |
| Zhao-Jun Wang, Fang Zhao, Chen-Fang Wang, Xiu-Min Zhang, Yi Xiao, Fang Zhou, Mei-Na Wu, Jun Zhang, Jin-Shun Qi, Wei Yan. Xestospongin C, a Reversible IP3 Receptor Antagonist, Alleviates the Cognitive and Pathological Impairments in APP/PS1 Mice of Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 72. issue 4. 2020-12-04. PMID:31683484. |
in addition, in vitro experiments showed that xec effectively ameliorated aβ1 - 42-induced early neuronal apoptosis and intracellular ca2+ overload in the primary hippocampal neurons. |
2020-12-04 |
2023-08-13 |
mouse |
| Marzena Ułamek-Kozioł, Stanisław J Czuczwar, Janusz Kocki, Sławomir Januszewski, Jacek Bogucki, Anna Bogucka-Kocka, Ryszard Plut. Dysregulation of Autophagy, Mitophagy, and Apoptosis Genes in the CA3 Region of the Hippocampus in the Ischemic Model of Alzheimer's Disease in the Rat. Journal of Alzheimer's disease : JAD. vol 72. issue 4. 2020-12-04. PMID:31707369. |
dysregulation of autophagy, mitophagy, and apoptosis genes in the ca3 region of the hippocampus in the ischemic model of alzheimer's disease in the rat. |
2020-12-04 |
2023-08-13 |
rat |
| Marzena Ułamek-Kozioł, Stanisław J Czuczwar, Janusz Kocki, Sławomir Januszewski, Jacek Bogucki, Anna Bogucka-Kocka, Ryszard Plut. Dysregulation of Autophagy, Mitophagy, and Apoptosis Genes in the CA3 Region of the Hippocampus in the Ischemic Model of Alzheimer's Disease in the Rat. Journal of Alzheimer's disease : JAD. vol 72. issue 4. 2020-12-04. PMID:31707369. |
there is currently no knowledge about the expression profile of the autophagy (becn1), mitophagy (bnip3), and apoptosis (casp3) genes in the ca3 region of the hippocampus after cerebral ischemia. |
2020-12-04 |
2023-08-13 |
rat |
| Alicja Skórkowska, Alicja Maciejska, Bartosz Pomierny, Weronika Krzyżanowska, Beata Starek-Świechowicz, Beata Bystrowska, Żaneta Broniowska, Grzegorz Kazek, Bogusława Budziszewsk. Effect of Combined Prenatal and Adult Benzophenone-3 Dermal Exposure on Factors Regulating Neurodegenerative Processes, Blood Hormone Levels, and Hematological Parameters in Female Rats. Neurotoxicity research. vol 37. issue 3. 2020-12-04. PMID:31970650. |
although bp-3 did not induce apoptosis in the hippocampus and frontal cortex, the increased extracellular glutamate concentration and lipid peroxidation, as well as impaired spatial memory, suggested that this compound also had adverse effects in the female brain yet was weaker than in males. |
2020-12-04 |
2023-08-13 |
rat |
| Zhilan Peng, Cai Zhang, Ling Yan, Yongping Zhang, Zhiyou Yang, Jiajia Wang, Cai Son. EPA is More Effective than DHA to Improve Depression-Like Behavior, Glia Cell Dysfunction and Hippcampal Apoptosis Signaling in a Chronic Stress-Induced Rat Model of Depression. International journal of molecular sciences. vol 21. issue 5. 2020-12-01. PMID:32150824. |
after epa or dha feeding, depression-like behavior, brain n-3/n-6 pufas profile, serum corticosterone and cholesterol concentration, hippocampal neurotransmitters, microglial and astrocyte related function, as well as neuronal apoptosis and survival signaling pathways were studied. |
2020-12-01 |
2023-08-13 |
rat |
| Sherif Rashad, Daisuke Saigusa, Takahiro Yamazaki, Yotaro Matsumoto, Yoshihisa Tomioka, Ritsumi Saito, Akira Uruno, Kuniyasu Niizuma, Masayuki Yamamoto, Teiji Tominag. Metabolic basis of neuronal vulnerability to ischemia; an in vivo untargeted metabolomics approach. Scientific reports. vol 10. issue 1. 2020-11-30. PMID:32300196. |
using untargeted liquid chromatography-mass spectrometry, we analyzed temporal metabolomic changes in ca1 and ca3 hippocampal areas following tgci in rats till the setting of neuronal apoptosis. |
2020-11-30 |
2023-08-13 |
rat |
| Cindy Lee, Reiko Sakurai, Eugene Shin, Ying Wang, Jie Liu, Virender K Reha. Antenatal PPAR-γ agonist pioglitazone stimulates fetal lung maturation equally in males and females. American journal of physiology. Lung cellular and molecular physiology. vol 319. issue 3. 2020-11-30. PMID:32579381. |
additionally, unlike dex, antenatal pgz did not increase hippocampal apoptosis. |
2020-11-30 |
2023-08-13 |
rat |
| Saira Cancela, Lucía Canclini, Gustavo Mourglia-Ettlin, Paola Hernández, Alicia Merlin. Neuroprotective effects of novel nitrones: In vitro and in silico studies. European journal of pharmacology. vol 871. 2020-11-27. PMID:31958456. |
in the present work, we have assessed ten non-cytotoxic nitrones for their ability to inhibit apoptosis plus their potential to reduce active caspase-3 and oxidative stress in the hippocampal neuronal cell line ht22. |
2020-11-27 |
2023-08-13 |
Not clear |
| Chunyu Zhou, Ferdous Taslima, Mona Abdelhamid, Sung-Woo Kim, Hiroyasu Akatsu, Makoto Michikawa, Cha-Gyun Jun. Beta-Amyloid Increases the Expression Levels of Tid1 Responsible for Neuronal Cell Death and Amyloid Beta Production. Molecular neurobiology. vol 57. issue 2. 2020-11-25. PMID:31686372. |
taken together, our results suggest that upregulated tid1 levels in the hippocampus of patients with ad and tg2576 mice induce apoptosis and increase aβ production, and tid1 may therefore be a suitable target in therapeutic interventions for ad. |
2020-11-25 |
2023-08-13 |
mouse |
| Qing Li, Xia-Qing Qin, Lin Sun, De-Xiang Liu, Qian Zhang, Fang Pan, David Ye. Chronic sub-anesthetic ketamine induces permanent hypolocomotion and impairment of hippocampus in adolescent cynomolgus monkeys. Neuroscience letters. vol 717. 2020-11-24. PMID:31863811. |
meanwhile, the markers of apoptosis in the hippocampus were assessed using terminal deoxynucleotidyl transferase-mediated biotinylated dutp nick end labeling (tunel), electron microscopy and western blotting. |
2020-11-24 |
2023-08-13 |
monkey |
| Peng Liu, Xing Deng, Ying Peng, Fang Zhou, Zelan Zu. Effect of Neotype Rectal Mild Hypothermia Therapy on Intestinal Bacterial Translocation in Rats with Hypoxic-Ischemic Brain Damage. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2020-11-24. PMID:32017761. |
background previous studies have shown that a neotype rectal cooling device can induce mild hypothermia (mh) in sprague-dawley rats with ischemic-hypoxic brain damage (hibd) and inhibit cell apoptosis in the hippocampal cal region, and does not cause damage to rectal tissues. |
2020-11-24 |
2023-08-13 |
rat |
| Attalla Farag El-Kott, Mashael Mohammed Bin-Meferij, Samy M Eleawa, Majed M Alshehr. Kaempferol Protects Against Cadmium Chloride-Induced Memory Loss and Hippocampal Apoptosis by Increased Intracellular Glutathione Stores and Activation of PTEN/AMPK Induced Inhibition of Akt/mTOR Signaling. Neurochemical research. vol 45. issue 2. 2020-11-23. PMID:31768814. |
kaempferol protects against cadmium chloride-induced memory loss and hippocampal apoptosis by increased intracellular glutathione stores and activation of pten/ampk induced inhibition of akt/mtor signaling. |
2020-11-23 |
2023-08-13 |
Not clear |
| Hongxia Che, Lingyu Zhang, Lin Ding, Wancui Xie, Xiaoming Jiang, Changhu Xue, Tiantian Zhang, Yuming Wan. EPA-enriched ethanolamine plasmalogen and EPA-enriched phosphatidylethanolamine enhance BDNF/TrkB/CREB signaling and inhibit neuronal apoptosis in vitro and in vivo. Food & function. vol 11. issue 2. 2020-11-23. PMID:32043504. |
in the present study, primary cultured hippocampal neurons and cognitive deficiency rats were used to compare the effects of epa-ppe and epa-pe on brain-derived neurotrophic factor (bdnf)/tropomyosin receptor kinase b (trkb)/camp response element-binding protein (creb) signaling and neuronal apoptosis. |
2020-11-23 |
2023-08-13 |
rat |
| Huimin Kong, Huaili Wang, Zhihong Zhuo, Zhenbiao Li, Peichao Tian, Jing Wu, Jian Liu, Zheng Chen, Jiyao Zhang, Qiang Lu. Inhibition of miR-181a-5p reduces astrocyte and microglia activation and oxidative stress by activating SIRT1 in immature rats with epilepsy. Laboratory investigation; a journal of technical methods and pathology. vol 100. issue 9. 2020-11-23. PMID:32461588. |
inhibition of mir-181a-5p protected the hippocampus against epilepsy, including hippocampal insults, neuronal apoptosis, astrocyte and microglia activation, neuroinflammation, oxidative stress, mitochondrial function, and cognitive dysfunction. |
2020-11-23 |
2023-08-13 |
rat |
| Zhenjie Zhu, Min Ge, Chunlei Li, Liqiang Yu, Yudan Gu, Yuming Hu, Zhilong Ca. Effects of p38 MAPK signaling pathway on cognitive function and recovery of neuronal function after hypoxic-ischemic brain injury in newborn rats. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 78. 2020-11-17. PMID:32360159. |
twenty-four hours after modeling, the expression of p-p38 mapk protein and apoptosis related genes in rat hippocampal tissues was detected by tunel staining, qrt-pcr and western blot. |
2020-11-17 |
2023-08-13 |
rat |
| Zhenjie Zhu, Min Ge, Chunlei Li, Liqiang Yu, Yudan Gu, Yuming Hu, Zhilong Ca. Effects of p38 MAPK signaling pathway on cognitive function and recovery of neuronal function after hypoxic-ischemic brain injury in newborn rats. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 78. 2020-11-17. PMID:32360159. |
inhibition of p38 mapk signaling pathway can effectively improve the learning and memory ability and motor function of newborn rats with hibi, and reduce neuronal apoptosis in the hippocampal tissues, thereby promoting neuronal recovery. |
2020-11-17 |
2023-08-13 |
rat |