| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cai-Hong Liu, Yuan-Zhi Tan, Dan-Dan Li, Su-Su Tang, Xiao-An Wen, Yan Long, Hong-Bin Sun, Hao Hong, Mei H. Zileuton ameliorates depressive-like behaviors, hippocampal neuroinflammation, apoptosis and synapse dysfunction in mice exposed to chronic mild stress. International immunopharmacology. vol 78. 2020-10-21. PMID:31796384. |
it also significantly ameliorated hippocampal apoptosis, indicated by deceased number of tunel-positive cells, deceased ratio of cleaved caspase-3/procaspase-3 and increased ratio of bcl-2/bax. |
2020-10-21 |
2023-08-13 |
mouse |
| Feng Liang, Xin Fu, Yunpengfei Li, Fanglei Ha. Desoxyrhapontigenin attenuates neuronal apoptosis in an isoflurane-induced neuronal injury model by modulating the TLR-4/cyclin B1/Sirt-1 pathway. AMB Express. vol 10. issue 1. 2020-10-20. PMID:32997222. |
neuronal apoptosis was assessed in the hippocampus using the tunel assay, and protein expression of caspase-3, bax, and bcl-2 was measured by western blotting. |
2020-10-20 |
2023-08-13 |
rat |
| Qi Guo, Jing Zhang, Zhaoshi Zheng, Xinxin Li, Fuli Wang, Songyan Li. Lentivirus-mediated microRNA-26a-modified neural stem cells improve brain injury in rats with cerebral palsy. Journal of cellular physiology. vol 235. issue 2. 2020-10-16. PMID:31264214. |
the neurobehavioral functions, morphology, and ultrastructure of cerebral cortex and hippocampus, apoptosis of brain cells, expression of apoptosis-related protein caspase-3 and bax, together with the expression of the glial fibrillary acidic protein (gfap) in cerebral cortex and hippocampus were determined. |
2020-10-16 |
2023-08-13 |
rat |
| Etrat Hooshmandi, Maryam Moosavi, Hermann Katinger, Shima Sardab, Rasoul Ghasemi, Nader Maghsoud. CEPO (carbamylated erythropoietin)-Fc protects hippocampal cells in culture against beta amyloid-induced apoptosis: considering Akt/GSK-3β and ERK signaling pathways. Molecular biology reports. vol 47. issue 3. 2020-10-14. PMID:32067159. |
cepo (carbamylated erythropoietin)-fc protects hippocampal cells in culture against beta amyloid-induced apoptosis: considering akt/gsk-3β and erk signaling pathways. |
2020-10-14 |
2023-08-13 |
Not clear |
| Jing-Ying Lin, Wei-Wen Kuo, Rathinasamy Baskaran, Chia-Hua Kuo, Yun-An Chen, William Shao-Tsu Chen, Tsung-Jung Ho, Cecilia Hsuan Day, B Mahalakshmi, Chih-Yang Huan. Correction for: Swimming exercise stimulates IGF1/PI3K/Akt and AMPK/SIRT1/PGC1α survival signaling to suppress apoptosis and inflammation in aging hippocampus. Aging. vol 12. issue 16. 2020-10-10. PMID:32889802. |
correction for: swimming exercise stimulates igf1/pi3k/akt and ampk/sirt1/pgc1α survival signaling to suppress apoptosis and inflammation in aging hippocampus. |
2020-10-10 |
2023-08-13 |
Not clear |
| Busarin Arunsak, Wasana Pratchayasakul, Patchareeya Amput, Kenneth Chattipakorn, Theetouch Tosukhowong, Sasiwan Kerdphoo, Thidarat Jaiwongkum, Chanisa Thonusin, Siripong Palee, Nipon Chattipakorn, Siriporn C Chattipakor. Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor exerts greater efficacy than atorvastatin on improvement of brain function and cognition in obese rats. Archives of biochemistry and biophysics. vol 689. 2020-10-09. PMID:32592802. |
oxidative stress, blood brain barrier breakdown, microglial hyperactivity, synaptic dysplasticity, apoptosis, amyloid proteins production in the hippocampus and cognitive decline were found in hfd-fed rats. |
2020-10-09 |
2023-08-13 |
rat |
| Busarin Arunsak, Wasana Pratchayasakul, Patchareeya Amput, Kenneth Chattipakorn, Theetouch Tosukhowong, Sasiwan Kerdphoo, Thidarat Jaiwongkum, Chanisa Thonusin, Siripong Palee, Nipon Chattipakorn, Siriporn C Chattipakor. Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor exerts greater efficacy than atorvastatin on improvement of brain function and cognition in obese rats. Archives of biochemistry and biophysics. vol 689. 2020-10-09. PMID:32592802. |
atorvastatin and pcsk9 inhibitor therapies equally attenuated hippocampal apoptosis and amyloid protein production in hfd-fed rats. |
2020-10-09 |
2023-08-13 |
rat |
| Song-Jiang Zhang, Shao-Hua Su, Jian-Feng Ga. [Electroacupuncture improves learning-memory ability possibly by suppressing apoptosis and down-regulating expression of apoptosis-related proteins in hippocampus and cerebral cortex in immature mice with Alzheimer's disease]. Zhen ci yan jiu = Acupuncture research. vol 45. issue 8. 2020-10-09. PMID:32869569. |
[electroacupuncture improves learning-memory ability possibly by suppressing apoptosis and down-regulating expression of apoptosis-related proteins in hippocampus and cerebral cortex in immature mice with alzheimer's disease]. |
2020-10-09 |
2023-08-13 |
mouse |
| Song-Jiang Zhang, Shao-Hua Su, Jian-Feng Ga. [Electroacupuncture improves learning-memory ability possibly by suppressing apoptosis and down-regulating expression of apoptosis-related proteins in hippocampus and cerebral cortex in immature mice with Alzheimer's disease]. Zhen ci yan jiu = Acupuncture research. vol 45. issue 8. 2020-10-09. PMID:32869569. |
to investigate the effect of electroacupuncture (ea) at "baihui"(gv20), "fengfu"(gv16) and bilateral "shenshu"(bl23) on learning-memory ability, apoptosis in the hippocampus and expression of aβ, caspase 3, bax and bcl-2 proteins in the hippocampus and cerebral cortex in immature mice with alzheimer's disease (ad), so as to explore its mechanism underlying improvement of ad. |
2020-10-09 |
2023-08-13 |
mouse |
| Masome Rashno, Shahab Ghaderi, Ali Nesari, Layasadat Khorsandi, Yaghoob Farbood, Alireza Sarkak. Chrysin attenuates traumatic brain injury-induced recognition memory decline, and anxiety/depression-like behaviors in rats: Insights into underlying mechanisms. Psychopharmacology. vol 237. issue 6. 2020-10-06. PMID:32088834. |
cortical and hippocampal neuronal apoptosis and neuroinflammation are associated with behavioral deficits following traumatic brain injury (tbi). |
2020-10-06 |
2023-08-13 |
rat |
| Ashutosh Kumar, Vikas Pareek, Muneeb A Faiq, Pavan Kumar, Chiman Kumari, Himanshu N Singh, Sanjib K Ghos. Transcriptomic analysis of the signature of neurogenesis in human hippocampus suggests restricted progenitor cell progression post-childhood. IBRO reports. vol 9. 2020-10-02. PMID:32995658. |
therefore, this study aimed to examine whether a comprehensive transcriptomic analysis of signature markers of neurogenesis, supplemented with markers of gliogenesis, vasculogenesis, cell proliferation, and apoptosis, may help discern essential aspects of adult hippocampal neurogenesis in humans. |
2020-10-02 |
2023-08-13 |
human |
| Xue Zhou, Wenda Li, Xiaohui Chen, Xiaoyu Yang, Zhibin Zhou, Dihan Lu, Xia Fen. Dose-dependent effects of sevoflurane exposure during early lifetime on apoptosis in hippocampus and neurocognitive outcomes in Sprague-Dawley rats. International journal of physiology, pathophysiology and pharmacology. vol 8. issue 3. 2020-10-01. PMID:27785338. |
dose-dependent effects of sevoflurane exposure during early lifetime on apoptosis in hippocampus and neurocognitive outcomes in sprague-dawley rats. |
2020-10-01 |
2023-08-13 |
rat |
| Xue Zhou, Wenda Li, Xiaohui Chen, Xiaoyu Yang, Zhibin Zhou, Dihan Lu, Xia Fen. Dose-dependent effects of sevoflurane exposure during early lifetime on apoptosis in hippocampus and neurocognitive outcomes in Sprague-Dawley rats. International journal of physiology, pathophysiology and pharmacology. vol 8. issue 3. 2020-10-01. PMID:27785338. |
only 2.3% sevoflurane induced hippocampal neural apoptosis via the mitochondrial-dependent pathway. |
2020-10-01 |
2023-08-13 |
rat |
| Xue Zhou, Wenda Li, Xiaohui Chen, Xiaoyu Yang, Zhibin Zhou, Dihan Lu, Xia Fen. Dose-dependent effects of sevoflurane exposure during early lifetime on apoptosis in hippocampus and neurocognitive outcomes in Sprague-Dawley rats. International journal of physiology, pathophysiology and pharmacology. vol 8. issue 3. 2020-10-01. PMID:27785338. |
in conclusions, higher dose of sevoflurane lead to histopathological changes and apoptosis in neonatal rat hippocampus, as well as temporal neurocognition deficits. |
2020-10-01 |
2023-08-13 |
rat |
| Je Hoon Park, Il Gyu Ko, Sung Eun Kim, Jun Jang Jin, Lakkyong Hwang, Chang Ju Kim, Soo Hwan Yoon, Jongki Hong, Jun Young Chung, Deok Won Le. Dexmedetomidine Oral Mucosa Patch for Sedation Suppresses Apoptosis in Hippocampus of Normal Rats. International neurourology journal. vol 21. issue Suppl 1. 2020-10-01. PMID:28446017. |
dexmedetomidine oral mucosa patch for sedation suppresses apoptosis in hippocampus of normal rats. |
2020-10-01 |
2023-08-13 |
rat |
| Je Hoon Park, Il Gyu Ko, Sung Eun Kim, Jun Jang Jin, Lakkyong Hwang, Chang Ju Kim, Soo Hwan Yoon, Jongki Hong, Jun Young Chung, Deok Won Le. Dexmedetomidine Oral Mucosa Patch for Sedation Suppresses Apoptosis in Hippocampus of Normal Rats. International neurourology journal. vol 21. issue Suppl 1. 2020-10-01. PMID:28446017. |
the effects of the dexmedetomidine oral mucosa patch on cell proliferation and apoptosis in the hippocampus were evaluated. |
2020-10-01 |
2023-08-13 |
rat |
| Jing Wu, Shuangying Hao, Xiao-Ru Sun, Hui Zhang, Huihui Li, Hongting Zhao, Mu-Huo Ji, Jian-Jun Yang, Kuanyu L. Elamipretide (SS-31) Ameliorates Isoflurane-Induced Long-Term Impairments of Mitochondrial Morphogenesis and Cognition in Developing Rats. Frontiers in cellular neuroscience. vol 11. 2020-10-01. PMID:28487636. |
we found that early exposure to isoflurane caused remarkable reactive oxygen species (ros) accumulation, mitochondrial deformation and neuronal apoptosis in hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Juan Lu, Yan Guo, Chang-Qing Guo, Xue-Min Shi, Ning-Yu Du, Rui-Li Zhao, Wen-Ping Du, Jing-Rong Liang, Shi-Peng Zhu, Huan Che. Acupuncture with reinforcing and reducing twirling manipulation inhibits hippocampal neuronal apoptosis in spontaneously hypertensive rats. Neural regeneration research. vol 12. issue 5. 2020-10-01. PMID:28616034. |
acupuncture with reinforcing and reducing twirling manipulation inhibits hippocampal neuronal apoptosis in spontaneously hypertensive rats. |
2020-10-01 |
2023-08-13 |
rat |
| Jihong Xing, Jian L. Effects of mTOR on Neurological Deficits after Transient Global Ischemia. Translational neuroscience. vol 8. 2020-10-01. PMID:28729914. |
blocking mtor using rapamycin attenuated upregulation of pro-inflammatory cytokines (namely il-1β, il-6 and tnf-α), and caspase-3, indicating cell apoptosis and also promoting the levels of vascular endothelial growth factor (vegf) and its subtype receptor vegfr-2 in the hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Ahmad Karkhah, Ramin Ataee, Amin Atai. Morphine pre- and post-conditioning exacerbates apoptosis in rat hippocampus cells in a model of homocysteine-induced oxidative stress. Biomedical reports. vol 7. issue 4. 2020-10-01. PMID:28928969. |
morphine pre- and post-conditioning exacerbates apoptosis in rat hippocampus cells in a model of homocysteine-induced oxidative stress. |
2020-10-01 |
2023-08-13 |
rat |