| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaoying Gao, Mian Guo, Dawei Meng, Feixiang Sun, Lianyue Guan, Ying Cui, Yan Zhao, Xichun Wang, Xin Gu, Jiahang Sun, Sihua Q. Silencing MicroRNA-134 Alleviates Hippocampal Damage and Occurrence of Spontaneous Seizures After Intraventricular Kainic Acid-Induced Status Epilepticus in Rats. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31031600. |
western blot showed that a mir-134 antagonist suppressed lesion-induced endoplasmic reticulum (er) stress and apoptosis related expression of chop, bim and cytochrome c, while facilitated the expression of creb at 24 h post ka-induced lesion in the hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Hussein Allawi Hussein, Ali Moghimi, Ali Roohbakhs. Anticonvulsant and ameliorative effects of pioglitazone on cognitive deficits, inflammation and apoptosis in the hippocampus of rat pups exposed to febrile seizure. Iranian journal of basic medical sciences. vol 22. issue 3. 2020-10-01. PMID:31156787. |
anticonvulsant and ameliorative effects of pioglitazone on cognitive deficits, inflammation and apoptosis in the hippocampus of rat pups exposed to febrile seizure. |
2020-10-01 |
2023-08-13 |
rat |
| Zun-Wei Liu, Jun-Jie Zhao, Hong-Gang Pang, Jin-Ning Son. Vascular endothelial growth factor A promotes platelet adhesion to collagen IV and causes early brain injury after subarachnoid hemorrhage. Neural regeneration research. vol 14. issue 10. 2020-10-01. PMID:31169190. |
tunel was used to detect apoptosis in the hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Elahe Mirarab, Vida Hojati, Golamhassan Vaezi, Abdolhossein Shiravi, Mehdi Khaksar. Obestatin inhibits apoptosis and astrogliosis of hippocampal neurons following global cerebral ischemia reperfusion via antioxidant and anti-inflammatory mechanisms. Iranian journal of basic medical sciences. vol 22. issue 6. 2020-10-01. PMID:31231488. |
obestatin inhibits apoptosis and astrogliosis of hippocampal neurons following global cerebral ischemia reperfusion via antioxidant and anti-inflammatory mechanisms. |
2020-10-01 |
2023-08-13 |
rat |
| Cuicui Kong, Fangfang Miao, Yan Wu, Tianlong Wan. Oxycodone suppresses the apoptosis of hippocampal neurons induced by oxygen-glucose deprivation/recovery through caspase-dependent and caspase-independent pathways via κ- and δ-opioid receptors in rats. Brain research. vol 1721. 2020-10-01. PMID:31276638. |
oxycodone suppresses the apoptosis of hippocampal neurons induced by oxygen-glucose deprivation/recovery through caspase-dependent and caspase-independent pathways via κ- and δ-opioid receptors in rats. |
2020-10-01 |
2023-08-13 |
rat |
| Cuicui Kong, Fangfang Miao, Yan Wu, Tianlong Wan. Oxycodone suppresses the apoptosis of hippocampal neurons induced by oxygen-glucose deprivation/recovery through caspase-dependent and caspase-independent pathways via κ- and δ-opioid receptors in rats. Brain research. vol 1721. 2020-10-01. PMID:31276638. |
cerebral ischemia/reperfusion injury (ciri) can lead to perioperative neurocognitive disorders (pnd) during clinical recanalization procedures in cerebral vessels, principally due to neuronal apoptosis in the hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Ming Li, Chan Chen, Weiyi Zhang, Rui Gao, Qiao Wang, Hai Chen, Shu Zhang, Xiaobo Mao, Mathis Leblanc, Adam Behensky, Zheng Zhang, Lu Gan, Hai Yu, Tao Zhu, Jin Li. Identification of the Potential Key Long Non-coding RNAs in Aged Mice With Postoperative Cognitive Dysfunction. Frontiers in aging neuroscience. vol 11. 2020-10-01. PMID:31379560. |
surgery-induced inflammatory cytokines and apoptosis were significantly increased in hippocampal tissues of aged mice. |
2020-10-01 |
2023-08-13 |
mouse |
| Nan Wang, Jinting He, Chengliang Pan, Jiaoqi Wang, Ming Ma, Xinxiu Shi, Zhongxin X. Resveratrol Activates Autophagy via the AKT/mTOR Signaling Pathway to Improve Cognitive Dysfunction in Rats With Chronic Cerebral Hypoperfusion. Frontiers in neuroscience. vol 13. 2020-10-01. PMID:31481868. |
these findings suggest that resveratrol improves cognitive function in a rat model of cch and reduces oxidative stress-induced neuronal damage in the frontal cortex and hippocampus by activating autophagy and inhibiting neuronal apoptosis. |
2020-10-01 |
2023-08-13 |
rat |
| Alexander Bracke, Grazyna Domanska, Katharina Bracke, Steffen Harzsch, Jens van den Brandt, Barbara Bröker, Oliver von Bohlen Und Halbac. Obesity Impairs Mobility and Adult Hippocampal Neurogenesis. Journal of experimental neuroscience. vol 13. 2020-10-01. PMID:31765441. |
adult hippocampal neurogenesis was examined using specific markers for cell proliferation (phosphohistone h3), neuronal differentiation (doublecortin), and apoptosis (caspase 3). |
2020-10-01 |
2023-08-13 |
mouse |
| Mia Kim, Tae-Woon Kim, Chang-Ju Kim, Mal-Soon Shin, Minha Hong, Hye-Sang Park, Sang-Seo Par. Berberine Ameliorates Brain Inflammation in Poloxamer 407-Induced Hyperlipidemic Rats. International neurourology journal. vol 23. issue Suppl 2. 2020-10-01. PMID:31795609. |
this study investigated the effects of berberine on poloxamer-407-induced brain inflammation by evaluating its effects on short-term memory, cell proliferation, inflammation, and apoptosis in the hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Tingting Meng, Shiman Shen, Cheng Li, Xuehua Li. MicroRNA-1236-3p/translationally controlled tumor protein (TPT1) axis participates in congenital hypothyroidism progression by regulating neuronal apoptosis. Experimental and therapeutic medicine. vol 19. issue 1. 2020-10-01. PMID:31885695. |
mir-1236-3p inhibitor prevented hippocampal neuron apoptosis induced by ch induction, which was reversed by tpt1-sirna transfection. |
2020-10-01 |
2023-08-13 |
rat |
| Ning-Ning Ji, Liang Wu, Bo-Ming Shao, Qing-Xiang Meng, Jin-Nan Xu, Hao-Wen Zhu, Yong-Mei Zhan. CTL-Derived Granzyme B Participates in Hippocampal Neuronal Apoptosis Induced by Cardiac Arrest and Resuscitation in Rats. Frontiers in neurology. vol 10. 2020-10-01. PMID:31920929. |
ctl-derived granzyme b participates in hippocampal neuronal apoptosis induced by cardiac arrest and resuscitation in rats. |
2020-10-01 |
2023-08-13 |
rat |
| Ning-Ning Ji, Liang Wu, Bo-Ming Shao, Qing-Xiang Meng, Jin-Nan Xu, Hao-Wen Zhu, Yong-Mei Zhan. CTL-Derived Granzyme B Participates in Hippocampal Neuronal Apoptosis Induced by Cardiac Arrest and Resuscitation in Rats. Frontiers in neurology. vol 10. 2020-10-01. PMID:31920929. |
hippocampal neuronal apoptosis is a devastating consequence of cardiac arrest (ca) and subsequent cardiopulmonary resuscitation (cpr). |
2020-10-01 |
2023-08-13 |
rat |
| Ning-Ning Ji, Liang Wu, Bo-Ming Shao, Qing-Xiang Meng, Jin-Nan Xu, Hao-Wen Zhu, Yong-Mei Zhan. CTL-Derived Granzyme B Participates in Hippocampal Neuronal Apoptosis Induced by Cardiac Arrest and Resuscitation in Rats. Frontiers in neurology. vol 10. 2020-10-01. PMID:31920929. |
in this study, we assessed the contribution of cytotoxic t lymphocyte (ctl)-derived toxic mediator granzyme b (gra-b) to the hippocampal neuronal apoptosis following ca/cpr in rats. |
2020-10-01 |
2023-08-13 |
rat |
| Ning-Ning Ji, Liang Wu, Bo-Ming Shao, Qing-Xiang Meng, Jin-Nan Xu, Hao-Wen Zhu, Yong-Mei Zhan. CTL-Derived Granzyme B Participates in Hippocampal Neuronal Apoptosis Induced by Cardiac Arrest and Resuscitation in Rats. Frontiers in neurology. vol 10. 2020-10-01. PMID:31920929. |
pretreatment with gra-b inhibitor suppressed gra-b release, attenuated hippocampal neuronal apoptosis, as well as improved cognitive impairment. |
2020-10-01 |
2023-08-13 |
rat |
| Erika Rodríguez-Martínez, Concepcion Nava-Ruiz, Elsa Escamilla-Chimal, Gabino Borgonio-Perez, Selva Rivas-Arancibi. The Effect of Chronic Ozone Exposure on the Activation of Endoplasmic Reticulum Stress and Apoptosis in Rat Hippocampus. Frontiers in aging neuroscience. vol 8. 2020-09-30. PMID:27826237. |
the effect of chronic ozone exposure on the activation of endoplasmic reticulum stress and apoptosis in rat hippocampus. |
2020-09-30 |
2023-08-13 |
rat |
| Jing-Ning Yang, Jun Chen, Min Xia. A protease-activated receptor 1 antagonist protects against global cerebral ischemia/reperfusion injury after asphyxial cardiac arrest in rabbits. Neural regeneration research. vol 12. issue 2. 2020-09-30. PMID:28400806. |
additionally, in the hippocampus, cell apoptosis, polymorphonuclear cell infiltration, and c-jun levels were decreased, whereas extracellular signal-regulated kinase phosphorylation levels were increased. |
2020-09-30 |
2023-08-13 |
rabbit |
| Ya-Jie Zhang, Meng-Jun Wu, Hai Yu, Jin Li. Emulsified isoflurane postconditioning improves survival and neurological outcomes in a rat model of cardiac arrest. Experimental and therapeutic medicine. vol 14. issue 1. 2020-09-30. PMID:28672894. |
moreover, the neural deficit score and memory function were improved in the eiso-4ml group, and this treatment also ameliorated brain hippocampal cell injury and apoptosis. |
2020-09-30 |
2023-08-13 |
rat |
| Xinwu Huang, Guozhou Lu, Guochun Li, Hua Li, Beihua Li, Jiazhen Yin, Shousong Ca. Dynamic Changes in the Renin-Angiotensin-Aldosterone System and the Beneficial Effects of Renin-Angiotensin-Aldosterone Inhibitors on Spatial Learning and Memory in a Rat Model of Chronic Cerebral Ischemia. Frontiers in neuroscience. vol 11. 2020-09-30. PMID:28690496. |
therefore, we studied the dynamic changes in the raas in the blood, cerebral cortex, and hippocampus and the effects of raas inhibitors on spatial learning and memory and hippocampal apoptosis in a rat model of chronic cerebral ischemia (cci) established by bilateral ligation of the common carotid arteries of rats. |
2020-09-30 |
2023-08-13 |
rat |
| Xinwu Huang, Guozhou Lu, Guochun Li, Hua Li, Beihua Li, Jiazhen Yin, Shousong Ca. Dynamic Changes in the Renin-Angiotensin-Aldosterone System and the Beneficial Effects of Renin-Angiotensin-Aldosterone Inhibitors on Spatial Learning and Memory in a Rat Model of Chronic Cerebral Ischemia. Frontiers in neuroscience. vol 11. 2020-09-30. PMID:28690496. |
spatial learning and memory and hippocampal apoptosis were evaluated on day 30 by morris water maze test (navigation and space exploration tests) and terminal dexynucleotidyl transferase (tdt)-mediated dutp nick end labeling (tunel) assay, respectively, after rats were orally administered with distilled water (dw), renin inhibitor aliskiren (30 mg/kg), ang converting enzyme inhibitor enalapril (4 mg/kg), or ang ii receptor antagonist candesartan (2 mg/kg) daily for 30 days. |
2020-09-30 |
2023-08-13 |
rat |