| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yueying Liu, Jieru Chen, Meifang Jin, Zhenhong Li, Tian Tian, Lili Li, Hong N. Relationship between changes in mitochondrial function and hippocampal neuronal apoptosis after recurrent convulsion during developmental stage. Experimental and therapeutic medicine. vol 16. issue 1. 2020-09-30. PMID:29896232. |
the aim of the present study was to establish a recurrent convulsion model during the developmental stage using inhalation of flurothyl, and to observe the relationship between the changes in mitochondrial function in hippocampal neurons and hippocampal neuronal apoptosis after recurrent convulsion. |
2020-09-30 |
2023-08-13 |
rat |
| Yingjun Zhou, Fashui Hong, Yusheng Tian, Xiangyu Zhao, Jie Hong, Yuguan Ze, Ling Wan. Nanoparticulate titanium dioxide-inhibited dendritic development is involved in apoptosis and autophagy of hippocampal neurons in offspring mice. Toxicology research. vol 6. issue 6. 2020-09-30. PMID:30090551. |
nanoparticulate titanium dioxide-inhibited dendritic development is involved in apoptosis and autophagy of hippocampal neurons in offspring mice. |
2020-09-30 |
2023-08-13 |
mouse |
| Xian-Jun Wang, Mei-Hong Wang, Xiao-Ting Fu, Ya-Jun Hou, Wang Chen, Da-Chen Tian, Su-Yun Bai, Xiao-Yan F. Selenocysteine antagonizes oxygen glucose deprivation-induced damage to hippocampal neurons. Neural regeneration research. vol 13. issue 8. 2020-09-30. PMID:30106056. |
in this study, the in vitro protective potential and mechanism of action of sec against ogd-induced apoptosis and neurotoxicity were evaluated in ht22 mouse hippocampal neurons. |
2020-09-30 |
2023-08-13 |
mouse |
| Jianghua Yu, Zhiqin Shi, Xudong Su, Yi Zhou, Bin Li, Shan Wang, Lijing Jia, Bo Zhao, Mengchu Zhu, Xiaohong Feng, Kuochang Yin, Weiping Wan. Expression of Bcl-2 and Bad in hippocampus of status epileptic rats and molecular mechanism of intervened recombinant human erythropoietin. Experimental and therapeutic medicine. vol 16. issue 2. 2020-09-30. PMID:30116338. |
injury of hippocampal neurons in status epilepticus (se) sd rats kindled by pentylenetetrazol (ptz) were studied, and the changes of apoptosis neurons, protein expression of bad and bcl-2 alone and combined application of phosphatidyl inositol 3-kinase (pi3k) inhibitor ly294002 and recombinant human erythropoietin (rhuepo) were evaluated for the possible mechanisms of rhuepo. |
2020-09-30 |
2023-08-13 |
human |
| Jianghua Yu, Zhiqin Shi, Xudong Su, Yi Zhou, Bin Li, Shan Wang, Lijing Jia, Bo Zhao, Mengchu Zhu, Xiaohong Feng, Kuochang Yin, Weiping Wan. Expression of Bcl-2 and Bad in hippocampus of status epileptic rats and molecular mechanism of intervened recombinant human erythropoietin. Experimental and therapeutic medicine. vol 16. issue 2. 2020-09-30. PMID:30116338. |
apoptosis of hippocampal neurons was detected by tunel method; expression of phosphorylation protein kinase b (p-pkb/p-akt), bcl-2 and bad were detected by immunohistochemistry; the expression of bcl-2 mrna, bad mrna in hippocampal neurons of rats were detected through reverse transcription polymerase chain reaction (rt-pcr); the expression of akt, p-akt and bcl-2, bad protein in hippocampal neurons of rats were detected by western blotting. |
2020-09-30 |
2023-08-13 |
human |
| Juan Ding, Yu Shao, Hui-Hui Zhou, Quan-Rui Ma, Yi-Wei Zhang, Yin-Xiu Ding, Yu-Qing He, Juan Li. Effect of NMDA on proliferation and apoptosis in hippocampal neural stem cells treated with MK-801. Experimental and therapeutic medicine. vol 16. issue 2. 2020-09-30. PMID:30116364. |
effect of nmda on proliferation and apoptosis in hippocampal neural stem cells treated with mk-801. |
2020-09-30 |
2023-08-13 |
Not clear |
| Xiao Li, Rui-Zhen Liu, Qi Zeng, Zhi-Hua Huang, Jian-Dong Zhang, Zong-Liang Liu, Jing Zeng, Hai Xia. 3'-Daidzein sulfonate sodium protects against memory impairment and hippocampal damage caused by chronic cerebral hypoperfusion. Neural regeneration research. vol 13. issue 9. 2020-09-30. PMID:30127116. |
results showed that dss treatment greatly improved the learning and memory deficits of rats with cch, reduced apoptosis of neurons in the hippocampal ca1, ca3 regions and dentate gyrus, and increased the phosphorylation of pka, erk1/2, and creb in the hippocampus. |
2020-09-30 |
2023-08-13 |
rat |
| Somayeh Kouhestani, Adele Jafari, Parvin Babae. Kaempferol attenuates cognitive deficit Neural regeneration research. vol 13. issue 10. 2020-09-30. PMID:30136699. |
the present study investigated the effects of kaempferol (kmp) isolated from the extract of mespilus germanica l. (medlar) leaves on cognitive impairment, hippocampal antioxidants, apoptosis, lipid peroxidation and neuro-inflammation markers in ovariectomized (ovx) rat models of sporadic ad. |
2020-09-30 |
2023-08-13 |
rat |
| Fangping Bao, Xianhui Kang, Qing Xie, Jian W. HIF-α/PKM2 and PI3K-AKT pathways involved in the protection by dexmedetomidine against isoflurane or bupivacaine-induced apoptosis in hippocampal neuronal HT22 cells. Experimental and therapeutic medicine. vol 17. issue 1. 2020-09-30. PMID:30651766. |
hif-α/pkm2 and pi3k-akt pathways involved in the protection by dexmedetomidine against isoflurane or bupivacaine-induced apoptosis in hippocampal neuronal ht22 cells. |
2020-09-30 |
2023-08-13 |
Not clear |
| Fangping Bao, Xianhui Kang, Qing Xie, Jian W. HIF-α/PKM2 and PI3K-AKT pathways involved in the protection by dexmedetomidine against isoflurane or bupivacaine-induced apoptosis in hippocampal neuronal HT22 cells. Experimental and therapeutic medicine. vol 17. issue 1. 2020-09-30. PMID:30651766. |
the present study investigated the mechanism underlying the protective effect of dexmedetomidine (dex) on hippocampal neuronal ht22 cell apoptosis induced by the anesthetics isoflurane and bupivacaine. |
2020-09-30 |
2023-08-13 |
Not clear |
| Hannah C Leeson, Tailoi Chan-Ling, Michael D Lovelace, Jeremy C Brownlie, Ben J Gu, Michael W Weibl. P2X7 receptor signaling during adult hippocampal neurogenesis. Neural regeneration research. vol 14. issue 10. 2020-09-30. PMID:31169175. |
regulation of hippocampal neurogenesis is complex and multifaceted, and numerous signaling pathways converge to modulate cell proliferation, apoptosis, and clearance of cellular debris, as well as synaptic integration of newborn immature neurons. |
2020-09-30 |
2023-08-13 |
Not clear |
| Zhuo Liu, Yuanshan Han, Hongqing Zhao, Weixu Luo, Ling Jia, Yuhong Wan. Glu-mGluR2/3-ERK Signaling Regulates Apoptosis of Hippocampal Neurons in Diabetic-Depression Model Rats. Evidence-based complementary and alternative medicine : eCAM. vol 2019. 2020-09-30. PMID:31281399. |
glu-mglur2/3-erk signaling regulates apoptosis of hippocampal neurons in diabetic-depression model rats. |
2020-09-30 |
2023-08-13 |
rat |
| Zhuo Liu, Yuanshan Han, Hongqing Zhao, Weixu Luo, Ling Jia, Yuhong Wan. Glu-mGluR2/3-ERK Signaling Regulates Apoptosis of Hippocampal Neurons in Diabetic-Depression Model Rats. Evidence-based complementary and alternative medicine : eCAM. vol 2019. 2020-09-30. PMID:31281399. |
here, we investigated the contribution of the glu-mglur2/3-erk signaling pathway to apoptosis of hippocampal neurons in dd model rats. |
2020-09-30 |
2023-08-13 |
rat |
| Riguang Zhao, Kun Zhao, Hongjun Su, Peng Zhang, Na Zha. Resveratrol ameliorates brain injury via the TGF-β-mediated ERK signaling pathway in a rat model of cerebral hemorrhage. Experimental and therapeutic medicine. vol 18. issue 5. 2020-09-30. PMID:31602214. |
the results demonstrated that treatment with resveratrol (10 mg/kg/day) decreased cerebral water content, hippocampal cell apoptosis and cerebral infarct volume compared with the pbs-treated group. |
2020-09-30 |
2023-08-13 |
human |
| Haiying Dong, Weiliang Cong, Xiwen Guo, Yuhua Wang, Shengju Tong, Qiang Li, Chengchong L. β-asarone relieves chronic unpredictable mild stress induced depression by regulating the extracellular signal-regulated kinase signaling pathway. Experimental and therapeutic medicine. vol 18. issue 5. 2020-09-30. PMID:31616508. |
in addition, the apoptosis of hippocampal neuronal cells was determined by flow cytometry, gene expression levels were detected by reverse transcription-quantitative polymerase chain reaction and protein levels were determined by western blot assay. |
2020-09-30 |
2023-08-13 |
rat |
| Haiying Dong, Weiliang Cong, Xiwen Guo, Yuhua Wang, Shengju Tong, Qiang Li, Chengchong L. β-asarone relieves chronic unpredictable mild stress induced depression by regulating the extracellular signal-regulated kinase signaling pathway. Experimental and therapeutic medicine. vol 18. issue 5. 2020-09-30. PMID:31616508. |
furthermore, β-asarone significantly decreased the apoptosis rate of hippocampal neuronal cells in rats subjected to cums. |
2020-09-30 |
2023-08-13 |
rat |
| F Edward Dude. Does Hippocampal Neurogenesis after Kainate-induced Apoptosis In Neonatal Rats Replace Lost Neurons? Epilepsy currents. vol 3. issue 6. 2020-09-29. PMID:15346162. |
does hippocampal neurogenesis after kainate-induced apoptosis in neonatal rats replace lost neurons? |
2020-09-29 |
2023-08-12 |
rat |
| Zhuangzhi Meng, Jianguo Li, Honglin Zhao, Haiying Liu, Guowei Zhang, Lingzhan Wang, H E Hu, D I Li, Mingjing Liu, Fulong Bi, Xiaoping Wang, Geng Tian, Qiang Liu, Batu Bure. Resveratrol relieves ischemia-induced oxidative stress in the hippocampus by activating SIRT1. Experimental and therapeutic medicine. vol 10. issue 2. 2020-09-29. PMID:26622348. |
the results demonstrate the neuroprotective and antioxidant effects of resveratrol against ischemia-induced apoptosis in the rat hippocampus. |
2020-09-29 |
2023-08-13 |
rat |
| Zheng-Jian Liao, Ri-Sheng Liang, Song-Sheng Shi, Chun-Hua Wang, Wei-Zhong Yan. Effect of baicalin on hippocampal damage in kainic acid-induced epileptic mice. Experimental and therapeutic medicine. vol 12. issue 3. 2020-09-29. PMID:27588062. |
the results showed that baicalin significantly attenuated neuronal damage and apoptosis in the hippocampus 72 h after se. |
2020-09-29 |
2023-08-13 |
mouse |
| Jian Sun, Xiao-Ling Chen, Jin-Yu Zheng, Jian-Wei Zhou, Zheng-Liang M. Astragaloside IV protects new born rats from anesthesia-induced apoptosis in the developing brain. Experimental and therapeutic medicine. vol 12. issue 3. 2020-09-29. PMID:27588101. |
the results showed that pre-treatment of as iv significantly inhibited isoflurane-induced neural apoptosis in the hippocampus of new born rats, and such protection was accompanied by reduced levels of caspase-3, nuclear factor-κb activation and phosphorylated c-jun n-terminal kinase, extracellular signal-regulated kinase and increased levels of b-cell lymphoma-2, glycogen synthase kinase-3β, klotho and phosphorylated protein kinase b. |
2020-09-29 |
2023-08-13 |
rat |