| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ji-Eun Kim, Hye-Won Hyun, Su-Ji Min, Tae-Cheon Kan. Sustained HSP25 Expression Induces Clasmatodendrosis via ER Stress in the Rat Hippocampus. Frontiers in cellular neuroscience. vol 11. 2020-09-29. PMID:28275338. |
in the present study, we investigated whether hsp25 is involved in astroglial apoptosis or clasmatodendrosis (autophagic astroglial death) in the rat hippocampus induced by status epilepticus (se). |
2020-09-29 |
2023-08-13 |
human |
| Feixiao Xue, Cai Shi, Qingjie Chen, Weijian Hang, Liangtao Xia, Yue Wu, Sophia Z Tao, Jie Zhou, Anbing Shi, Juan Che. Melatonin Mediates Protective Effects against Kainic Acid-Induced Neuronal Death through Safeguarding ER Stress and Mitochondrial Disturbance. Frontiers in molecular neuroscience. vol 10. 2020-09-29. PMID:28293167. |
melatonin is known to protect hippocampal neurons from ka-induced apoptosis, but the exact mechanisms underlying melatonin protective effects against neuronal mitochondria disorder and er stress remain uncertain. |
2020-09-29 |
2023-08-13 |
Not clear |
| Xin He, Jiankui Sun, Xiaoyu Huan. Expression of caspase-3, Bax and Bcl-2 in hippocampus of rats with diabetes and subarachnoid hemorrhage. Experimental and therapeutic medicine. vol 15. issue 1. 2020-09-29. PMID:29399092. |
tunel method was used to detect cell apoptosis of hippocampus. |
2020-09-29 |
2023-08-13 |
rat |
| Xin He, Jiankui Sun, Xiaoyu Huan. Expression of caspase-3, Bax and Bcl-2 in hippocampus of rats with diabetes and subarachnoid hemorrhage. Experimental and therapeutic medicine. vol 15. issue 1. 2020-09-29. PMID:29399092. |
in conclusion, hippocampal neuron apoptosis was induced by diabetes + sah and expression levels of caspase-3, bax and bcl-2 were also increased. |
2020-09-29 |
2023-08-13 |
rat |
| Yuan Zhou, Hao-Kang Zhang, Fei Liu, Gang Lei, Peng Liu, Tong Jiao, Yong-Hui Dan. Altered Light Conditions Contribute to Abnormalities in Emotion and Cognition Through HINT1 Dysfunction in C57BL/6 Mice. Frontiers in behavioral neuroscience. vol 12. 2020-09-29. PMID:29937721. |
based on the potential links between histidine triad nucleotide binding protein 1 (hint1) and mood disorders, we also examined the expression of hint1 and related apoptosis factors in the suprachiasmatic nucleus (scn), prefrontal cortex (pfc), nucleus accumbens (nac) and hippocampus (hip). |
2020-09-29 |
2023-08-13 |
mouse |
| Lili Zhong, Hong Liu, Weijia Zhang, Xu Liu, Bo Jiang, Hongxin Fei, Zhongren Su. Ellagic acid ameliorates learning and memory impairment in APP/PS1 transgenic mice via inhibition of β-amyloid production and tau hyperphosphorylation. Experimental and therapeutic medicine. vol 16. issue 6. 2020-09-29. PMID:30542451. |
hippocampal regions were examined for the presence of amyloid plaques, neuronal apoptosis and tau phosphorylation. |
2020-09-29 |
2023-08-13 |
mouse |
| Lili Zhong, Hong Liu, Weijia Zhang, Xu Liu, Bo Jiang, Hongxin Fei, Zhongren Su. Ellagic acid ameliorates learning and memory impairment in APP/PS1 transgenic mice via inhibition of β-amyloid production and tau hyperphosphorylation. Experimental and therapeutic medicine. vol 16. issue 6. 2020-09-29. PMID:30542451. |
the results demonstrated that ea treatment ameliorated spatial learning and memory impairment in app/ps1 mice and significantly reduced neuronal apoptosis and aβ deposition in the hippocampus (p<0.05 and p<0.01). |
2020-09-29 |
2023-08-13 |
mouse |
| Siamak Shahidi, Nasrin Hashemi-Firouzi, Simin Afshar, Sara Soleimani Asl, Alireza Komak. Protective Effects of 5-HT1A Receptor Inhibition and 5-HT2A Receptor Stimulation Against Streptozotocin-Induced Apoptosis in the Hippocampus. The Malaysian journal of medical sciences : MJMS. vol 26. issue 2. 2020-09-29. PMID:31447607. |
protective effects of 5-ht1a receptor inhibition and 5-ht2a receptor stimulation against streptozotocin-induced apoptosis in the hippocampus. |
2020-09-29 |
2023-08-13 |
rat |
| Wenxian Li, Di Wei, Jiaxing Lin, Jianye Liang, Xiaomei Xie, Kangping Song, Li'an Huan. Dl-3-n-Butylphthalide Reduces Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion Through GDNF/GFRα1/Ret Signaling Preventing Hippocampal Neuron Apoptosis. Frontiers in cellular neuroscience. vol 13. 2020-09-29. PMID:31456664. |
dl-3-n-butylphthalide reduces cognitive impairment induced by chronic cerebral hypoperfusion through gdnf/gfrα1/ret signaling preventing hippocampal neuron apoptosis. |
2020-09-29 |
2023-08-13 |
rat |
| Wenxian Li, Di Wei, Jiaxing Lin, Jianye Liang, Xiaomei Xie, Kangping Song, Li'an Huan. Dl-3-n-Butylphthalide Reduces Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion Through GDNF/GFRα1/Ret Signaling Preventing Hippocampal Neuron Apoptosis. Frontiers in cellular neuroscience. vol 13. 2020-09-29. PMID:31456664. |
glial cell line-derived neurotrophic factor (gdnf)/gdnf family receptor alpha-1 (gfrα1)/receptor tyrosine kinase (ret) signaling is altered in the hippocampus of cch rats; however, nbp treatment improved cognitive function, protected against hippocampal neuron apoptosis |
2020-09-29 |
2023-08-13 |
rat |
| Jun Xiong, Huijun Wang, Feng Mu, Zhanxue Liu, Yin Bao, Yongxing Su. MiR-125b-5p Inhibitor Might Protect Against Sevoflurane-induced Cognitive Impairments by Targeting LIMK1. Current neurovascular research. vol 16. issue 4. 2020-09-29. PMID:31490755. |
mir-125b-5p contributed to anesthesia-induced hippocampal apoptosis. |
2020-09-29 |
2023-08-13 |
Not clear |
| He-Ying Zhong, Zhou Yang, Zhen Qiu, Shao-Qing Lei, Zhong-Yuan Xi. The neuroprotective mechanism of 2-arachidonoylglycerol 2-AG against non-caspase-dependent apoptosis in mice hippocampal neurons following MCAO. Neuropsychiatric disease and treatment. vol 15. 2020-09-29. PMID:31692526. |
the neuroprotective mechanism of 2-arachidonoylglycerol 2-ag against non-caspase-dependent apoptosis in mice hippocampal neurons following mcao. |
2020-09-29 |
2023-08-13 |
mouse |
| He-Ying Zhong, Zhou Yang, Zhen Qiu, Shao-Qing Lei, Zhong-Yuan Xi. The neuroprotective mechanism of 2-arachidonoylglycerol 2-AG against non-caspase-dependent apoptosis in mice hippocampal neurons following MCAO. Neuropsychiatric disease and treatment. vol 15. 2020-09-29. PMID:31692526. |
in this study, the neuroprotective mechanism of 2-arachidonoylglycerol 2-ag against non-caspase-dependent apoptosis in mice hippocampal neurons following mcao was investigated. |
2020-09-29 |
2023-08-13 |
mouse |
| Jian-Hua Qin, Xue-Rong Zhang, Liang He, Jun Zhu, Qing-Jun M. Effect of sevoflurane and halothane anesthesia on cognitive function and immune function in young rats. Saudi journal of biological sciences. vol 25. issue 1. 2020-09-28. PMID:29379356. |
we also scrutinized the serum proinflammatory cytokines including il-10, il-4 and il-2; brain level il-1β; hippocampal neuronal apoptosis concentration were estimated. |
2020-09-28 |
2023-08-13 |
rat |
| Jian-Hua Qin, Xue-Rong Zhang, Liang He, Jun Zhu, Qing-Jun M. Effect of sevoflurane and halothane anesthesia on cognitive function and immune function in young rats. Saudi journal of biological sciences. vol 25. issue 1. 2020-09-28. PMID:29379356. |
the hippocampal neuron apoptosis was significantly increased in halothane and sevoflurane + halothane group as compared to control group rats, respectively. |
2020-09-28 |
2023-08-13 |
rat |
| Bin Xu, Li-Min Lang, Shuai Lian, Jing-Ru Guo, Jian-Fa Wang, Huan-Min Yang, Shi-Ze L. Oxidation Stress-Mediated MAPK Signaling Pathway Activation Induces Neuronal Loss in the CA1 and CA3 Regions of the Hippocampus of Mice Following Chronic Cold Exposure. Brain sciences. vol 9. issue 10. 2020-09-28. PMID:31614701. |
male c57bl/6 mice were exposed to an environment of 4 °c, 3 h per day for 1, 2, and 3 weeks and homeostasis in the hippocampus and neuronal apoptosis were evaluated by western blotting, immunohistochemistry, tdt-mediated dutp nick-end labeling (tunel) staining, and immunofluorescence. |
2020-09-28 |
2023-08-13 |
mouse |
| Bin Xu, Li-Min Lang, Shuai Lian, Jing-Ru Guo, Jian-Fa Wang, Huan-Min Yang, Shi-Ze L. Oxidation Stress-Mediated MAPK Signaling Pathway Activation Induces Neuronal Loss in the CA1 and CA3 Regions of the Hippocampus of Mice Following Chronic Cold Exposure. Brain sciences. vol 9. issue 10. 2020-09-28. PMID:31614701. |
the phenomena of oxidation stress, mapk signaling pathway activation, anti-oxidation protein release, neuronal apoptosis increases, and neuronal proliferation inhibition were demonstrated in the ca1 and ca3 regions of mouse hippocampal tissues following cold exposure. |
2020-09-28 |
2023-08-13 |
mouse |
| Dong-Qi Lin, Xin-Ying Cai, Chun-Hua Wang, Bin Yang, Ri-Sheng Lian. Optimal concentration of necrostatin-1 for protecting against hippocampal neuronal damage in mice with status epilepticus. Neural regeneration research. vol 15. issue 5. 2020-09-28. PMID:31719260. |
therefore, in this study, we investigated the effects of necrostatin-1 on hippocampal neurons in mice with status epilepticus, and, furthermore, we tested different amounts of the compound to identify the optimal concentration for inhibiting necroptosis and apoptosis. |
2020-09-28 |
2023-08-13 |
mouse |
| Anna O Giarratana, Shavonne Teng, Sahithi Reddi, Cynthia Zheng, Derek Adler, Smita Thakker-Varia, Janet Alde. BDNF Val66Met Genetic Polymorphism Results in Poor Recovery Following Repeated Mild Traumatic Brain Injury in a Mouse Model and Treatment With AAV-BDNF Improves Outcomes. Frontiers in neurology. vol 10. 2020-09-28. PMID:31787925. |
we found that relative to injured val66val carriers, injured val66met carriers had a larger inflammation volume and increased levels of neurodegeneration, apoptosis, p-tau, activated microglia, and gliosis in the cortex and/or hippocampus at 1 and/or 21 days post-injury (dpi). |
2020-09-28 |
2023-08-13 |
mouse |
| Bo Dam Lee, Jae-Myung Yoo, Seong Yeon Baek, Fu Yi Li, Dai-Eun Sok, Mee Ree Ki. 3,3'-Diindolylmethane Promotes BDNF and Antioxidant Enzyme Formation via TrkB/Akt Pathway Activation for Neuroprotection against Oxidative Stress-Induced Apoptosis in Hippocampal Neuronal Cells. Antioxidants (Basel, Switzerland). vol 9. issue 1. 2020-09-28. PMID:31861353. |
3,3'-diindolylmethane promotes bdnf and antioxidant enzyme formation via trkb/akt pathway activation for neuroprotection against oxidative stress-induced apoptosis in hippocampal neuronal cells. |
2020-09-28 |
2023-08-13 |
mouse |