| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ferah Bulut, Muhammed Adam, Aslışah Özgen, Munevver Gizem Hekim, Sibel Ozcan, Sinan Canpolat, Mete Ozca. Protective Effects of Chronic Humanin Treatment in Mice with Diabetic Encephalopathy: A Focus on Oxidative Stress, Inflammation, and Apoptosis. Behavioural brain research. 2023-07-19. PMID:37467966. |
our results showed that in the prefrontal cortex and hippocampus of the diabetes group, oxidative stress parameters, pro-inflammatory cytokines, apoptosis and, blood glucose levels were increased, while antioxidant and anti-inflammatory cytokines were diminished compared to the control group. |
2023-07-19 |
2023-08-14 |
mouse |
| Kewarin Jinawong, Chanon Piamsiri, Nattayaporn Apaijai, Chayodom Maneechote, Hiranya Pintana, Titikorn Chunchai, Busarin Arunsak, Nipon Chattipakorn, Siriporn C Chattipakor. Treatment with apoptosis inhibitor restores cognitive impairment in rats with myocardial infarction. Biochimica et biophysica acta. Molecular basis of disease. 2023-07-15. PMID:37453581. |
moreover, z-vad provided greater efficacy than enalapril in enhancing mitophagy, neurogenesis, synaptic proteins and reducing apoptosis in hippocampus of mi rats. |
2023-07-15 |
2023-08-14 |
rat |
| Mina Gholami, A Wallace Hayes, Hamidreza Jamaati, Antoni Sureda, Majid Motaghineja. Role of apoptosis and autophagy in mediating tramadol-induced neurodegeneration in the rat hippocampus. Molecular biology reports. 2023-07-15. PMID:37453963. |
role of apoptosis and autophagy in mediating tramadol-induced neurodegeneration in the rat hippocampus. |
2023-07-15 |
2023-08-14 |
rat |
| Leila Chodari, Maedeh Ghasemi, Nasrin Mehranfar. Alterations in expression of α1-adrenergic receptors possibly are involved in prevention of age-associated apoptosis in rat hippocampus by treadmill exercise. Journal of complementary & integrative medicine. 2023-07-10. PMID:37428454. |
alterations in expression of α1-adrenergic receptors possibly are involved in prevention of age-associated apoptosis in rat hippocampus by treadmill exercise. |
2023-07-10 |
2023-08-14 |
rat |
| Leila Chodari, Maedeh Ghasemi, Nasrin Mehranfar. Alterations in expression of α1-adrenergic receptors possibly are involved in prevention of age-associated apoptosis in rat hippocampus by treadmill exercise. Journal of complementary & integrative medicine. 2023-07-10. PMID:37428454. |
α1-adrenergic receptors (ars) can either trigger or suppress apoptosis, therefore, here we determined the impact of treadmill exercise on the expression of the apoptosis regulatory proteins as well as α1-ar subtypes α1a- and α1b-ars, in order to elucidate a possible association between apoptosis and the hippocampal expression of α1-ars in aged male rats. |
2023-07-10 |
2023-08-14 |
rat |
| Yanfu Ding, Feifei Chen, Weitao Yang, Xiaobin Fu, Yuanyuan Xi. SENP5 deteriorates traumatic brain injury via SUMO2-dependent suppression of E2F1 SUMOylation. Acta biochimica et biophysica Sinica. 2023-07-05. PMID:37403456. |
senp5 is overexpressed in hippocampal tissues of tbi rats, and inhibition of senp5 reduces neurological function scores, decreases brain water content, inhibits apoptosis in hippocampal tissues, and attenuates brain injury caused in rats. |
2023-07-05 |
2023-08-14 |
rat |
| Liang Xing, Wei Wei, Cuina Zhang, Bingquan Gao, Jianke Feng, Leilei M. [Resveratrol improves cognitive function in severely burned rats by inhibiting hippocampal NF-κB/JNK pathway]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 39. issue 7. 2023-07-05. PMID:37403719. |
the apoptosis of hippocampal neurons was tested by terminal deoxynuclectidyl transferase-mediated dutp-biotin nick end labeling assay (tunel). |
2023-07-05 |
2023-08-14 |
rat |
| Liang Xing, Wei Wei, Cuina Zhang, Bingquan Gao, Jianke Feng, Leilei M. [Resveratrol improves cognitive function in severely burned rats by inhibiting hippocampal NF-κB/JNK pathway]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 39. issue 7. 2023-07-05. PMID:37403719. |
consistently, the rats in rsv group had a reduced concentration of tnf-α and il-6 in serum, decreased mrna and protein expressions of tnf-α and il-6 in hippocampus, and decreased apoptosis rate and relative expression of p-nf-κb p65/nf-κb p65 and p-jnk/jnk in hippocampal neurons. |
2023-07-05 |
2023-08-14 |
rat |
| Liang Xing, Wei Wei, Cuina Zhang, Bingquan Gao, Jianke Feng, Leilei M. [Resveratrol improves cognitive function in severely burned rats by inhibiting hippocampal NF-κB/JNK pathway]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 39. issue 7. 2023-07-05. PMID:37403719. |
conclusion rsv alleviates inflammatory response and hippocampal neuronal apoptosis by inhibiting nf-κb/jnk pathway, thereby improving cognitive function in severely burned rats. |
2023-07-05 |
2023-08-14 |
rat |
| Yadong Zhou, Xianjing Zhang, Hui Yang, Bo Chu, Maochuan Zhen, Junli Zhang, Lin Yan. Mechanism of cAMP response element-binding protein 1/death-associated protein kinase 1 axis-mediated hippocampal neuron apoptosis in rat brain injury after cardiopulmonary resuscitation. Neuroscience. 2023-07-05. PMID:37406926. |
mechanism of camp response element-binding protein 1/death-associated protein kinase 1 axis-mediated hippocampal neuron apoptosis in rat brain injury after cardiopulmonary resuscitation. |
2023-07-05 |
2023-08-14 |
rat |
| Yadong Zhou, Xianjing Zhang, Hui Yang, Bo Chu, Maochuan Zhen, Junli Zhang, Lin Yan. Mechanism of cAMP response element-binding protein 1/death-associated protein kinase 1 axis-mediated hippocampal neuron apoptosis in rat brain injury after cardiopulmonary resuscitation. Neuroscience. 2023-07-05. PMID:37406926. |
nissl and tunel staining evaluated the pathological condition of hippocampus and apoptosis of hippocampal neurons respectively. |
2023-07-05 |
2023-08-14 |
rat |
| Yadong Zhou, Xianjing Zhang, Hui Yang, Bo Chu, Maochuan Zhen, Junli Zhang, Lin Yan. Mechanism of cAMP response element-binding protein 1/death-associated protein kinase 1 axis-mediated hippocampal neuron apoptosis in rat brain injury after cardiopulmonary resuscitation. Neuroscience. 2023-07-05. PMID:37406926. |
to conclude, creb1 suppresses hippocampal neuron apoptosis and mitigates brain injury after cpr by inhibiting dapk1 expression. |
2023-07-05 |
2023-08-14 |
rat |
| Arshad Ghaffari-Nasab, Gonja Javani, Hadi Yousefi, Rahim Sharafkhani, Sajjad Taghizade. Prolonged stress-induced depression-like behaviors in aged rats are mediated by endoplasmic reticulum stress and apoptosis in the hippocampus. Neuroscience research. 2023-07-01. PMID:37392834. |
prolonged stress-induced depression-like behaviors in aged rats are mediated by endoplasmic reticulum stress and apoptosis in the hippocampus. |
2023-07-01 |
2023-08-14 |
rat |
| Arshad Ghaffari-Nasab, Gonja Javani, Hadi Yousefi, Rahim Sharafkhani, Sajjad Taghizade. Prolonged stress-induced depression-like behaviors in aged rats are mediated by endoplasmic reticulum stress and apoptosis in the hippocampus. Neuroscience research. 2023-07-01. PMID:37392834. |
since investigating the molecular substrates that facilitate behavioral recovery may have important implications for understanding brain plasticity and resilience of individuals, we studied depressive-like behaviors in young and aged rats 6 weeks after chronic stress exposure as a recovery period and examined the levels of tnf-α and il-6 inflammatory cytokines, nadh oxidase activity, nadph oxidase, endoplasmic reticulum (er) stress markers, and apoptosis in the hippocampus. |
2023-07-01 |
2023-08-14 |
rat |
| Arshad Ghaffari-Nasab, Gonja Javani, Hadi Yousefi, Rahim Sharafkhani, Sajjad Taghizade. Prolonged stress-induced depression-like behaviors in aged rats are mediated by endoplasmic reticulum stress and apoptosis in the hippocampus. Neuroscience research. 2023-07-01. PMID:37392834. |
these data suggested that oxidative and er stress-induced apoptosis in the aging hippocampus may affect the recovery-related outcomes after the stress paradigm. |
2023-07-01 |
2023-08-14 |
rat |
| Igor Henrique Rodrigues de Paiva, Rodrigo Soares da Silva, Ingrid Prata Mendonça, Eduardo Duarte-Silva, José Roberto Botelho de Souza, Christina Alves Peixot. Fructooligosaccharide (FOS) and Galactooligosaccharide (GOS) Improve Neuroinflammation and Cognition By Up-regulating IRS/PI3K/AKT Signaling Pathway in Diet-induced Obese Mice. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2023-06-29. PMID:37382830. |
prebiotics inhibit neuroinflammation, neuronal apoptosis, and reactive gliosis in the hippocampus but restore synaptic plasticity, neuronal proliferation, and neurogenesis. |
2023-06-29 |
2023-08-14 |
mouse |
| Ying-Cai Zhao, Cheng-Cheng Wang, Xiao-Yue Li, Dan-Dan Wang, Yu-Ming Wang, Chang-Hu Xue, Min Wen, Tian-Tian Zhan. Supplementation of n-3 PUFAs in Adulthood Attenuated Susceptibility to Pentylenetetrazol Induced Epilepsy in Mice Fed with n-3 PUFAs Deficient Diet in Early Life. Marine drugs. vol 21. issue 6. 2023-06-27. PMID:37367679. |
notably, nutritional supplementation with n-3 pufas in adulthood for 17 days could significantly recover the brain n-3 fatty acid and alleviate the epilepsy susceptibility as well as raise seizure threshold to different levels by mediating the neurotransmitter disturbance and mitochondria-dependent apoptosis, demyelination, and neuroinflammation status of the hippocampus. |
2023-06-27 |
2023-08-14 |
mouse |
| Hua Liu, Yang Du, Lian Lin Liu, Qing Shan Liu, Hehui Mao, Yong Chen. Anti-depression-like effect of Mogroside V is related to the inhibition of inflammatory and oxidative stress pathways. European journal of pharmacology. 2023-06-26. PMID:37364672. |
mgv also significantly reduced oxidative stress damage and reduced the levels of apoptosis in hippocampal nerve cells. |
2023-06-26 |
2023-08-14 |
Not clear |
| Paola Leone, Yaiza M Arenas, Tiziano Balzano, Gergana Mincheva, Mar Martinez-Garcia, Carmina Montoliu, Marta Llansola, Vicente Felip. Patients died with steatohepatitis or liver cirrhosis show neuroinflammation and neuronal loss in hippocampus. European journal of neurology. 2023-06-21. PMID:37340928. |
hippocampal neuroinflammation could contribute to cognitive decline in patients with liver disease, but this has yet to be studied.the aims were to assess if hippocampus from patients died with steatohepatitis or cirrhosis show: 1) glial activation; 2) altered cytokine content; 3) immune cells infiltration; 4) neuronal apoptosis and 5) neuronal loss. |
2023-06-21 |
2023-08-14 |
Not clear |
| Rita Chaaya, Joel R Steele, Brian G Oliver, Hui Chen, Rita Machaalan. Effects of e-vapour and high-fat diet on the immunohistochemical staining of nicotinic acetylcholine receptors, apoptosis, microglia and astrocytes in the adult male mouse hippocampus. Journal of chemical neuroanatomy. 2023-06-21. PMID:37343645. |
effects of e-vapour and high-fat diet on the immunohistochemical staining of nicotinic acetylcholine receptors, apoptosis, microglia and astrocytes in the adult male mouse hippocampus. |
2023-06-21 |
2023-08-14 |
mouse |